Frontiers in Medicine

Original Research

Published on 20 Feb 2026

Integrating network pharmacology, molecular docking and dynamics simulation to decipher the antipyretic mechanisms of Xiaochaihu granules

in Pathology

Minghe Gu
Hong Liu
Cong Bi
Wenhui Situ
Haiyong Du
Aihua Lin
Junhua Zhang
Yiming Liu

Frontiers in Medicine

doi 10.3389/fmed.2026.1772991

Case Report

Accepted on 19 Feb 2026

A Rare Case of Clear Cell Sarcoma-like/Malignant Gastrointestinal Neuroectodermal Tumor in the Pancreas: Case Report and Literature Review

in Pathology

Jing Huang
Lu Zhou
Xiaoyu Chen
Yuzhen Huang
Ruwei Mo
Lixia Zeng
Shengming Wu
Wenqi Luo

Frontiers in Medicine

Case Report

Published on 18 Feb 2026

Penile pseudomyogenic hemangioendothelioma: a rare case report with clinicopathologic features and multidisciplinary management

in Pathology

Cecilia Carrión
Paola Sánchez
Daniel Moreira
Marlon Arias-Intriago
Juan S. Izquierdo-Condoy

Frontiers in Medicine

doi 10.3389/fmed.2026.1777602

138 views

Review

Published on 18 Feb 2026

Dynamic dual regulation of amphiregulin in liver pathophysiology: balancing regeneration and disease progression via the EGFR axis

in Pathology

Yi-Li Wang
De-Jiang Zhou
Qiong-Wan Wang
Ye Zhang
Wen-Jing Yang
Wen-Jie Tan
Hao-Yu Wang
Xiao-Wan Chen
San-Qiang Li

Frontiers in Medicine

doi 10.3389/fmed.2026.1697954

106 views

Original Research

Published on 16 Feb 2026

Efficient and explainable histopathology for cancer detection using dual-teacher distillation and integrated gradients

in Pathology

Khubab Ahmad
Saad Arif
Muhammad Hanif
Nazik Alturki
Muhammad Nabeel Asghar
Munam Ali Shah

Frontiers in Medicine

doi 10.3389/fmed.2026.1724419

233 views

Case Report

Published on 16 Feb 2026

Case Report: Membranous/cytoplasmic Ki-67 staining and PAX8-GLIS3 fusion: defining the clinicopathological spectrum of hyalinizing trabecular tumor to optimize patient management

in Pathology

Haining Huang
Ran Zhao
Liman Zhang
Shujun Ren
Jianli Liu
Dandan Yang
Junjun Zhang
Renya Zhang
Shuai Chen
Lei Li

Frontiers in Medicine

doi 10.3389/fmed.2026.1764079

201 views

Original Research

Published on 13 Feb 2026

Development and validation of a predictive model for pathological upgrading in colorectal polyps based on endoscopic forceps biopsy

in Pathology

Ziyao Cheng
Chang Zhang
Feng Yu

Frontiers in Medicine

doi 10.3389/fmed.2026.1748424

204 views

Original Research

Accepted on 12 Feb 2026

Lower Limb Edema Detection and Grading Classification Using Deep Learning and Image Enhancement Technologies

in Pathology

Ting-Wei Hu
Chao-Hung Wang
Min-Hui Liu
Hui-Huang Hsu
Tun-Wen Pai

Frontiers in Medicine

123 views

Original Research

Published on 12 Feb 2026

Dynamic C-reactive protein trajectories predict prolonged healing time in diabetic wounds: a machine learning model based on a single-center cohort with standardized wound size

in Pathology

Sichao Jiang
Qixuan Song
Junhuan Wang
Xiaohong Sun
Zhen Zhang
Shouyu Wang
Junwei Zong

Frontiers in Medicine

doi 10.3389/fmed.2026.1778003

289 views

Systematic Review

Accepted on 11 Feb 2026

MAPPING THE DEGENERATING INTERVERTEBRAL DISC: A SYSTEMATIC REVIEW OF HISTOLOGICAL EVIDENCE

in Pathology

Francesca Veronesi
Francesca Salamanna
Giuseppe Tedesco
Alberto Ruffilli
Francesco Rosa
Cesare Faldini
Gianluca Giavaresi

Frontiers in Medicine

Original Research

Accepted on 10 Feb 2026

Neuroendocrine-Vascular Interaction is Associated with Thalamocortical Disorganization and Cognitive Decline in Perimenopausal Hypertension

in Pathology

Taipeng Zeng
Xiaoyang Wang
Yuhang Zhang
Minghui Mao
Chengkun Hong
Zhen Yu
Hao Huang
Jianfeng Chu
Liyuan Fu

Frontiers in Medicine

112 views

Case Report

Published on 10 Feb 2026

Case Report: A rare case of Epstein–Barr virus mucocutaneous ulcers occurring in the eyeball and literature review

in Pathology

Xiaokang Ke
Qingping Zhang
Wenxian Huang
Jie Rao
Jiacai Ren
Juan Wu
Honglin Yan
Jing Yuan
Jingping Yuan
Huihua He

Frontiers in Medicine

doi 10.3389/fmed.2026.1749739

386 views

Original Research

Published on 09 Feb 2026

LBMNet: a hybrid multi-scale CNN–Mamba framework for enhanced 3D stroke lesion segmentation in MRI

in Pathology

Zhejun Kuang
Xingxue Yan
Jiaxuan Yu
Dawen Sun
Jian Zhao
Lei Sun

Frontiers in Medicine

doi 10.3389/fmed.2026.1759114

311 views

Correction

Accepted on 06 Feb 2026

Correction: Parameter-optimized generative adversarial network framework for synthetic MRI generation: fine-tuning critical variables for enhanced image fidelity

in Pathology

Anto Lourdu Xavier Raj Arockia Selvarathinam
Naveenkumar Anbalagan
Parvathaneni Naga Srinivasu
Jaeyoung Choi
Muhammad Fazal Ijaz

Frontiers in Medicine

244 views

Original Research

Accepted on 05 Feb 2026

Toxicokinetics and postmortem redistribution of amantadine in rats

in Pathology

Lingxiao Wang
Xiaomeng Sun
Chenxu Gao
Jinkai Wang
Jianbin Gong
Chen Zhe
Zhiwen Wei
Chao Zhang
Yun Keming

Frontiers in Medicine

109 views

Case Report

Accepted on 03 Feb 2026

Right ureterovesical junction cyst associated with ipsilateral renal agenesis: a case report of a possible Wolffian duct maldevelopment

in Pathology

Hao Lin
Junpeng Liu
Xinyao Sun
Jiaxi He
Jinhuan Yang
Derong Zhou
Yutong Fang
Bin Huang
Zeke Zhang

Frontiers in Medicine

109 views

Perspective

Published on 03 Feb 2026

Advancing the diagnosis of cardiac electrophysiological disorders in diabetes: integrating clinical, imaging, and molecular insights

in Pathology

Venkata Nagaraj Kakaraparthi
Paul Silvian Samuel
Lalitha Kakaraparthi
Vamsi Krishna Gannamaneni
Kumar Gular

Frontiers in Medicine

doi 10.3389/fmed.2026.1777638

300 views

Editorial

Published on 03 Feb 2026

Editorial: Paleoradiology and mummy studies for disease identification

in Pathology

Sahar N. Saleem
Dario Piombino-Mascali

Frontiers in Medicine

doi 10.3389/fmed.2026.1783130

452 views

Original Research

Published on 03 Feb 2026

Parameter-optimized generative adversarial network framework for synthetic MRI generation: fine-tuning critical variables for enhanced image fidelity

in Pathology

Anto Lourdu Xavier Raj Arockia Selvarathinam
Naveenkumar Anbalagan
Parvathaneni Naga Srinivasu
Jaeyoung Choi
Muhammad Fazal Ijaz

Frontiers in Medicine

doi 10.3389/fmed.2025.1731370

838 views

Original Research

Published on 02 Feb 2026

Deep learning and firearm wound classification: a pilot study

in Pathology

Giuseppe Delogu
Nicola Di Fazio
Gabriele Licciardello
Paola Frati
Cristoforo Pomara
Francesco Sessa

Frontiers in Medicine

doi 10.3389/fmed.2025.1646656

609 views

Original Research

Published on 02 Feb 2026

Integration of gut microbiota, Stroke Dysbiosis Index, and inflammatory biomarkers in assessing prognosis of acute ischemic stroke

in Pathology

Weny Rinawati
Aryati Aryati
Abdulloh Machin
Stefan Kiechl
Gregor Broessner

Frontiers in Medicine

doi 10.3389/fmed.2025.1707253

469 views

Original Research

Published on 02 Feb 2026

Automated tumor regression grade assessment and survival prediction in esophageal cancer via weakly supervised multiple instance learning

in Pathology

Zhengjin Liu
Lin Zhao
Ziqing Zhao
Wenjuan Qin
Jun Zhong
Fenglian Lin
Meizhen Lu
Ruixiang Guo
Qunhuang Guo
Hui Xu

Frontiers in Medicine

doi 10.3389/fmed.2026.1751768

506 views

Original Research

Published on 30 Jan 2026

A scalable and reliable deep learning framework for enhanced brain tumor detection and diagnosis using AI-based medical imaging

in Pathology

Sultan Ahmad
Stephen Neal Joshua Eali
Thirupathi Rao Nakka
Naceur Chihaoui
Tahani Alsubait
Humaira Khanam

Frontiers in Medicine

doi 10.3389/fmed.2026.1738796

508 views

Original Research

Published on 27 Jan 2026

Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway

in Pathology

Yubo Liu
Hansen Yang
Hongying Li
Shan Zhang
Han Yang
Yu Luo
Ting Hu
Zhenting Zhang
Xiaobo Peng
Yuanhe Wang

Frontiers in Medicine

doi 10.3389/fmed.2026.1768944

485 views

562 articles

articles

Integrating network pharmacology, molecular docking and dynamics simulation to decipher the antipyretic mechanisms of Xiaochaihu granules

A Rare Case of Clear Cell Sarcoma-like/Malignant Gastrointestinal Neuroectodermal Tumor in the Pancreas: Case Report and Literature Review

Penile pseudomyogenic hemangioendothelioma: a rare case report with clinicopathologic features and multidisciplinary management

Dynamic dual regulation of amphiregulin in liver pathophysiology: balancing regeneration and disease progression via the EGFR axis

Efficient and explainable histopathology for cancer detection using dual-teacher distillation and integrated gradients

Case Report: Membranous/cytoplasmic Ki-67 staining and PAX8-GLIS3 fusion: defining the clinicopathological spectrum of hyalinizing trabecular tumor to optimize patient management

Development and validation of a predictive model for pathological upgrading in colorectal polyps based on endoscopic forceps biopsy

Lower Limb Edema Detection and Grading Classification Using Deep Learning and Image Enhancement Technologies

Dynamic C-reactive protein trajectories predict prolonged healing time in diabetic wounds: a machine learning model based on a single-center cohort with standardized wound size

MAPPING THE DEGENERATING INTERVERTEBRAL DISC: A SYSTEMATIC REVIEW OF HISTOLOGICAL EVIDENCE

Neuroendocrine-Vascular Interaction is Associated with Thalamocortical Disorganization and Cognitive Decline in Perimenopausal Hypertension

Case Report: A rare case of Epstein–Barr virus mucocutaneous ulcers occurring in the eyeball and literature review

LBMNet: a hybrid multi-scale CNN–Mamba framework for enhanced 3D stroke lesion segmentation in MRI

Correction: Parameter-optimized generative adversarial network framework for synthetic MRI generation: fine-tuning critical variables for enhanced image fidelity

Toxicokinetics and postmortem redistribution of amantadine in rats

Right ureterovesical junction cyst associated with ipsilateral renal agenesis: a case report of a possible Wolffian duct maldevelopment

Advancing the diagnosis of cardiac electrophysiological disorders in diabetes: integrating clinical, imaging, and molecular insights

Editorial: Paleoradiology and mummy studies for disease identification

Parameter-optimized generative adversarial network framework for synthetic MRI generation: fine-tuning critical variables for enhanced image fidelity

Deep learning and firearm wound classification: a pilot study

Integration of gut microbiota, Stroke Dysbiosis Index, and inflammatory biomarkers in assessing prognosis of acute ischemic stroke

Automated tumor regression grade assessment and survival prediction in esophageal cancer via weakly supervised multiple instance learning

A scalable and reliable deep learning framework for enhanced brain tumor detection and diagnosis using AI-based medical imaging

Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway