Frontiers in Medicine

Original Research

Published on 27 Jan 2026

Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway

in Pathology

Yubo Liu
Hansen Yang
Hongying Li
Shan Zhang
Han Yang
Yu Luo
Ting Hu
Zhenting Zhang
Xiaobo Peng
Yuanhe Wang

Frontiers in Medicine

doi 10.3389/fmed.2026.1768944

485 views

Original Research

Accepted on 26 Jan 2026

Vertebrae and Intervertebral Discs Segmentation using Deep Learning-Based Model in Disability Analysis

in Pathology

Nizar Alsharif
Rajit Nair
Theyazn H.H Aldhyani
Nesren Farhah
Sultan Ahmad
Abdullah H. Al-Nefaie

Frontiers in Medicine

167 views

Review

Published on 20 Jan 2026

From tradition to healing: the promise of acupuncture in managing chronic fatigue syndrome

in Pathology

Delong Wang
Tiansong Yang
Yang Cui
Yuanyuan Qu
Chuwen Feng
Zhongren Sun
Miao Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1724290

938 views

Case Report

Published on 20 Jan 2026

Autoimmune GAD-positive rhombencephalitis with rare manifestation: a case report and literature review

in Pathology

Anas Khaled Zurayqi
Anas R. Tuqan
Anas M. Barabrah
Basel A. Zaben
Ruba Saadeh

Frontiers in Medicine

doi 10.3389/fmed.2025.1721582

668 views

Original Research

Published on 15 Jan 2026

Explainable AI for classifying vertebral fracture histology in digital spine pathology

in Pathology

Panyi Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1726453

754 views

Case Report

Published on 14 Jan 2026

Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma

in Pathology

Rui Xu
Wei Wang
Zhen Wang
Kun Lian
Yongchao Gao
Pengyan Guo
Pengyu Qiao
Yongjun Gao

Frontiers in Medicine

doi 10.3389/fmed.2025.1715197

744 views

Original Research

Published on 14 Jan 2026

Prognostic biomarkers for overall survival in patients undergoing surgery for bone metastases: a pan-cancer study

in Pathology

Elisa Belluzzi
Assunta Pozzuoli
Pietro Belloni
Maria Grazia Rodà
Andrea Angelini
Pietro Ruggieri

Frontiers in Medicine

doi 10.3389/fmed.2025.1655245

863 views

Case Report

Published on 12 Jan 2026

New mutation of CACNA1H p.Tyr613Phe in hyperaldosteronism: a case report

in Pathology

Qing Yan
Xinyi Qu
Rong Wang
Wenxuan Ji
Li Li
Qingqing Bi

Frontiers in Medicine

doi 10.3389/fmed.2025.1715935

515 views

Case Report

Published on 12 Jan 2026

Case Report: Concurrent autoimmune gastritis and high-grade dysplasia in a gastric hyperplastic polyp

in Pathology

Tianwa Wang
Jinfeng Luo
Yajing Han
Qiu Yang
Shusong Peng

Frontiers in Medicine

doi 10.3389/fmed.2025.1716969

655 views

Original Research

Published on 09 Jan 2026

Early prediction of diabetic retinopathy using a multimodal deep learning framework integrating fundus and OCT imaging

in Pathology

Abdel-Hamid M. Emara
Jawad Hasan Alkhateeb
Ghada Atteia
Aiman Turani
Jamal Zraqou
Zeinab Elsawaf
Abid Jameel

Frontiers in Medicine

doi 10.3389/fmed.2025.1741146

1,331 views

Systematic Review

Published on 09 Jan 2026

From radiomics to transformers in pancreatic cancer detection and prognosis

in Pathology

Maram Fahaad Almufareh
Samabia Tehsin
Mamoona Humayun
Sumaira Kausar
Asad Farooq
Haya Aldossary
Abeer Aljohani

Frontiers in Medicine

doi 10.3389/fmed.2025.1731922

1,163 views

Review

Published on 08 Jan 2026

Ginsenoside potential targeting hypoxia-inducible factor-1α as promising therapeutics for cancer: a review

in Pathology

Xindan Ai
Anning Li
Ruixue Feng
Hongkang Xu
Hao Yue
Zhe Wang
Yulin Dai

Frontiers in Medicine

doi 10.3389/fmed.2025.1703982

632 views

Case Report

Published on 07 Jan 2026

Splenic B-cell lymphoma/leukemia with prominent nucleoli and spontaneous splenic rupture: a case report and literature review

in Pathology

Riwei Wang
Yun Xia
Haoru Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1693164

929 views

Original Research

Accepted on 30 Dec 2025

Integrative Multi-Stage Deep Learning Framework for Ovarian Tumor Ultrasound Classification with Explainability and Confidence Estimation

in Pathology

Shtwai Alsubai
Ahmad Almadhor
Abdullah Al Hejaili

Frontiers in Medicine

301 views

Original Research

Published on 18 Dec 2025

Petrified child mummies by Paolo Gorini (19th century CE, Lodi, Lombardy, Italy): anthropological, pathological, and conservation perspectives

in Pathology

Omar Larentis
Ilaria Gorini
Michele Campus
Stefano Vanin
Enrica Tonina
Giuseppina Carta
Alberto Carli
Lisa De Luca
Dario Piombino-Mascali

Frontiers in Medicine

doi 10.3389/fmed.2025.1692282

2,277 views

Case Report

Published on 18 Dec 2025

Fibromatosis-like metaplastic carcinoma with aggressive metastasis and a TERT promoter mutation: a case report and literature review

in Pathology

Jie Chen
Yan Li
Xue Bing
Ting Wang
Wei Wang
Lei Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1722451

908 views

Original Research

Published on 18 Dec 2025

Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings

in Pathology

Molly Walkenhorst
Malay K. Basu
Wei Cui
Manish Kumar
Anusha Vallurupalli
Andrea Sitek
Xinyang Zhao
X. Long Zheng
Da Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1679484

1,233 views

Original Research

Published on 17 Dec 2025

Solute carrier family 1 member 1 in renal interstitial fibrosis: evaluating its influence on glutamate uptake and extracellular ion levels

in Pathology

Chun Yan Lv
Xian Kui Cheng
Sen Fang Luo
Wen Xuan Yang
Geng Lin Liu
Ting Ting Huang
Shi Gao Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1694428

1,049 views

Original Research

Published on 17 Dec 2025

Evaluation of the zinc-fingers and homeoboxes 3 as a potential biomarker for prognosis prediction in lung adenocarcinoma

in Pathology

Yanjie You
Wenmei Li
Ling Gao
Tiantian Li
Xiaoli Zhang
Xiaomei Luo

Frontiers in Medicine

doi 10.3389/fmed.2025.1728286

764 views

Original Research

Published on 16 Dec 2025

An explainable deep learning-based feature fusion model for acute lymphoblastic leukemia diagnosis and severity assessment

in Pathology

Hajra Khan
Muhammad Zaheer Sajid
Nauman Ali Khan
Muhammad Fareed Hamid
Ayman Youssef
Areesha Rehman
Nour Aburaed

Frontiers in Medicine

doi 10.3389/fmed.2025.1694024

1,441 views

Case Report

Published on 16 Dec 2025

Case Report: Experience in the diagnosis and treatment of a male patient with plasma cell mastitis in the lump stage and review of the literature

in Pathology

Li-Juan Chen
Zheng Dang

Frontiers in Medicine

doi 10.3389/fmed.2025.1595042

1,035 views

Case Report

Published on 12 Dec 2025

Dendritic fibromyxolipoma of the male breast: case report and literary review

in Pathology

Xiaolan Li
Demian Wu
Xiaoxue Tian
Ting Xu
Qiyao Ge
Shuai Luo
Jinjing Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1653754

613 views

Editorial

Published on 10 Dec 2025

Editorial: The impact of lipid metabolism on cancer progression and metastasis

in Pathology

Duygu Aydemir
Miguel Martin-Perez
Yoshiaki Sunami

Frontiers in Medicine

doi 10.3389/fmed.2025.1755140

745 views

Original Research

Published on 09 Dec 2025

Qiling decoction enhances the anti-tumor activity of abiraterone acetate by up-regulating miR-143 expression in abiraterone acetate-resistant prostate cancer cells

in Pathology

Lizhi Chen
Hongwen Cao
Peng Sun
Yigeng Feng
Lei Chen
Renjie Gao

Frontiers in Medicine

doi 10.3389/fmed.2025.1643506

811 views

563 articles

articles

Gastrodia elata fermentation alleviates methamphetamine-induced neuroinflammation and anxiety- and depression-like behaviors by regulating the PI3K-AKT signaling pathway

Vertebrae and Intervertebral Discs Segmentation using Deep Learning-Based Model in Disability Analysis

From tradition to healing: the promise of acupuncture in managing chronic fatigue syndrome

Autoimmune GAD-positive rhombencephalitis with rare manifestation: a case report and literature review

Explainable AI for classifying vertebral fracture histology in digital spine pathology

Case Report: Pathological confirmation and aggressive postoperative recurrence of WHO grade III rhabdoid meningioma

Prognostic biomarkers for overall survival in patients undergoing surgery for bone metastases: a pan-cancer study

New mutation of CACNA1H p.Tyr613Phe in hyperaldosteronism: a case report

Case Report: Concurrent autoimmune gastritis and high-grade dysplasia in a gastric hyperplastic polyp

Early prediction of diabetic retinopathy using a multimodal deep learning framework integrating fundus and OCT imaging

From radiomics to transformers in pancreatic cancer detection and prognosis

Ginsenoside potential targeting hypoxia-inducible factor-1α as promising therapeutics for cancer: a review

Splenic B-cell lymphoma/leukemia with prominent nucleoli and spontaneous splenic rupture: a case report and literature review

Integrative Multi-Stage Deep Learning Framework for Ovarian Tumor Ultrasound Classification with Explainability and Confidence Estimation

Petrified child mummies by Paolo Gorini (19th century CE, Lodi, Lombardy, Italy): anthropological, pathological, and conservation perspectives

Fibromatosis-like metaplastic carcinoma with aggressive metastasis and a TERT promoter mutation: a case report and literature review

Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings

Solute carrier family 1 member 1 in renal interstitial fibrosis: evaluating its influence on glutamate uptake and extracellular ion levels

Evaluation of the zinc-fingers and homeoboxes 3 as a potential biomarker for prognosis prediction in lung adenocarcinoma

An explainable deep learning-based feature fusion model for acute lymphoblastic leukemia diagnosis and severity assessment

Case Report: Experience in the diagnosis and treatment of a male patient with plasma cell mastitis in the lump stage and review of the literature

Dendritic fibromyxolipoma of the male breast: case report and literary review

Editorial: The impact of lipid metabolism on cancer progression and metastasis

Qiling decoction enhances the anti-tumor activity of abiraterone acetate by up-regulating miR-143 expression in abiraterone acetate-resistant prostate cancer cells