Frontiers in Medicine | Precision Medicine

Opinion

Published on 24 Sep 2021

Obesity and Dose of Anti-cancer Therapy: Are We Sure to Be on the Right Track in the Precision Medicine Era?

in Precision Medicine

Tania Rossi
Erika Bandini
William Balzi
Francesco Fabbri
Ilaria Massa
Roberta Maltoni

Frontiers in Medicine

doi 10.3389/fmed.2021.725346

3,479 views
7 citations

Original Research

Published on 16 Sep 2021

The Concentration of Large Extracellular Vesicles Differentiates Early Septic Shock From Infection

in Precision Medicine

Latthawan Monnamorn
Chutima Seree-aphinan
Piyatida Molika
Polathep Vichitkunakorn
Kovit Pattanapanyasat
Bodin Khwannimit
Raphatphorn Navakanitworakul

Frontiers in Medicine

doi 10.3389/fmed.2021.724371

4,240 views
7 citations

Original Research

Published on 14 Sep 2021

Non-invasive Urine Test for Molecular Classification of Clinical Significance in Newly Diagnosed Prostate Cancer Patients

in Precision Medicine

Jinan Guo
Xuhui Zhang
Taolin Xia
Heather Johnson
Xiaoyan Feng
Athanasios Simoulis
Alan H. B. Wu
Fei Li
Wanlong Tan
Allan Johnson

Frontiers in Medicine

doi 10.3389/fmed.2021.721554

4,608 views
2 citations

Original Research

Published on 13 Sep 2021

Novel MYO1D Missense Variant Identified Through Whole Exome Sequencing and Computational Biology Analysis Expands the Spectrum of Causal Genes of Laterality Defects

in Precision Medicine

Rabab Said Alsafwani
Khalidah K. Nasser
Thoraia Shinawi
Babajan Banaganapalli
Hanan Abdelhalim ElSokary
Zhaher F. Zaher
Noor Ahmad Shaik
Gaser Abdelmohsen
Jumana Yousuf Al-Aama
Adam J. Shapiro

Frontiers in Medicine

doi 10.3389/fmed.2021.724826

5,343 views
14 citations

Original Research

Published on 13 Sep 2021

Molecular Characteristics, Clinical Implication, and Cancer Immunity Interactions of Pyroptosis-Related Genes in Breast Cancer

in Precision Medicine

Dandan Xu
Zhipeng Ji
Ling Qiang

Frontiers in Medicine

doi 10.3389/fmed.2021.702638

11,439 views
54 citations

Original Research

Published on 09 Sep 2021

Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

in Precision Medicine

Sze Wa Chan
Tanya T. W. Chu
Chung Shun Ho
Alice P. S. Kong
Brian Tomlinson
Weiwei Zeng

Frontiers in Medicine

doi 10.3389/fmed.2021.683498

9,019 views
11 citations

Original Research

Published on 08 Sep 2021

Multi-Trait Genomic Risk Stratification for Type 2 Diabetes

in Precision Medicine

Palle Duun Rohde
Mette Nyegaard
Mads Kjolby
Peter Sørensen

Frontiers in Medicine

doi 10.3389/fmed.2021.711208

4,288 views
14 citations

Original Research

Published on 26 Aug 2021

Role of Immune Cell-Specific Hypermethylation Signatures in Classification and Risk Stratification of Breast Cancer

in Precision Medicine

Yong Chen
Fada Xia
Bo Jiang
Wenlong Wang
Xinying Li

Frontiers in Medicine

doi 10.3389/fmed.2021.674338

2,745 views
4 citations

Original Research

Published on 13 Aug 2021

Identification of Key Genes and Pathways in Persistent Hyperplastic Primary Vitreous of the Eye Using Bioinformatic Analysis

in Precision Medicine

Derin M. Thomas
Chitra Kannabiran
D. Balasubramanian

Frontiers in Medicine

doi 10.3389/fmed.2021.690594

7,898 views
22 citations

Original Research

Published on 11 Aug 2021

Isoflurane Suppresses Proliferation, Migration, and Invasion and Facilitates Apoptosis in Colorectal Cancer Cells Through Targeting miR-216

in Precision Medicine

Zhe Cai
Liangyuan Suo
Zeqing Huang

Frontiers in Medicine

doi 10.3389/fmed.2021.658926

3,881 views
12 citations

Original Research

Published on 09 Aug 2021

m6A RNA Methylation Regulator YTHDF1 Correlated With Immune Microenvironment Predicts Clinical Outcomes and Therapeutic Efficacy in Breast Cancer

in Precision Medicine

Ying Hu
Qinwen Pan
Minghao Wang
Xiang Ai
Yuzhao Yan
Yuan Tian
Yuting Jing
Peng Tang
Jun Jiang

Frontiers in Medicine

doi 10.3389/fmed.2021.667543

5,665 views
16 citations

Original Research

Published on 30 Jul 2021

Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss

in Precision Medicine

Nourah H. Al Qahtani
Sayed AbdulAzeez
Noor B. Almandil
Norah Fahad Alhur
Hind Saleh Alsuwat
Hatoon Ahmed Al Taifi
Ahlam A. Al-Ghamdi
B. Rabindran Jermy
Mohamed Abouelhoda
Shazia Subhani

Frontiers in Medicine

doi 10.3389/fmed.2021.699672

6,992 views
16 citations

Original Research

Published on 28 Jul 2021

rs12537 Is a Novel Susceptibility SNP Associated With Estrogen Receptor Positive Breast Cancer in Chinese Han Population

in Precision Medicine

Jingkai Xu
Guozheng Li
Mengyun Chen
Wenjing Li
Yaxing Wu
Xuejun Zhang
Yong Cui
Bo Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.708644

3,404 views
6 citations

Perspective

Published on 26 Jul 2021

Legal Challenges in Precision Medicine: What Duties Arising From Genetic and Genomic Testing Does a Physician Owe to Patients?

in Precision Medicine

Scott P. McGrath
Arthur E. Peabody
Derek Walton
Nephi Walton

Frontiers in Medicine

doi 10.3389/fmed.2021.663014

10,330 views
19 citations

Mini Review

Published on 23 Jul 2021

Extracellular Vesicles: A Novel Opportunity for Precision Medicine in Respiratory Diseases

in Precision Medicine

Jonathan M. Carnino
Zhi Hao Kwok
Yang Jin

Frontiers in Medicine

doi 10.3389/fmed.2021.661679

7,370 views
23 citations

Original Research

Published on 15 Jul 2021

A Novel RNA-Binding Protein Signature to Predict Clinical Outcomes and Guide Clinical Therapy in Gastric Cancer

in Precision Medicine

Zhigang Qiu
Haitao Jiang
Kun Ju
Xichun Liu

Frontiers in Medicine

doi 10.3389/fmed.2021.670141

4,135 views
5 citations

Review

Published on 08 Jul 2021

The “Slow Horse Racing Effect” on Lung Function in Adult Life in Chronic Obstructive Pulmonary Disease Associated to Biomass Exposure

in Precision Medicine

Alejandra Ramírez-Venegas
Francisco Montiel-Lopez
Ramces Falfan-Valencia
Gloria Pérez-Rubio
Raúl H Sansores

Frontiers in Medicine

doi 10.3389/fmed.2021.700836

5,199 views
20 citations

Original Research

Published on 25 Jun 2021

Saudi Familial Hypercholesterolemia Patients With Rare LDLR Stop Gain Variant Showed Variable Clinical Phenotype and Resistance to Multiple Drug Regimen

in Precision Medicine

Zuhier Ahmed Awan
Omran M. Rashidi
Bandar Ali Al-Shehri
Kaiser Jamil
Ramu Elango
Jumana Y. Al-Aama
Robert A. Hegele
Babajan Banaganapalli
Noor A. Shaik

Frontiers in Medicine

doi 10.3389/fmed.2021.694668

6,016 views
15 citations

Original Research

Published on 24 Jun 2021

FABP5, a Novel Immune-Related mRNA Prognostic Marker and a Target of Immunotherapy for Multiple Myeloma

in Precision Medicine

Haipeng Jia
Xiaofen Zhang
Xinxin Liu
Ruifang Qiao
Yan Liu
Sulong Lv
Hongbo Zhu
Jie Wang
Qiuhong Kong
Hong Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.667525

6,969 views
13 citations

Original Research

Published on 22 Jun 2021

Long Non-coding RNA SNHG12, a New Therapeutic Target, Regulates miR-199a-5p/Klotho to Promote the Growth and Metastasis of Intrahepatic Cholangiocarcinoma Cells

in Precision Medicine

Hong-Guo Yang
Tian-peng Wang
Sheng-an Hu
Chao-zhou Hu
Cheng-hang Jiang
Qiang He

Frontiers in Medicine

doi 10.3389/fmed.2021.680378

3,813 views
7 citations

Original Research

Published on 31 May 2021

Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2

in Precision Medicine

Vijay Kumar Bhardwaj
Rahul Singh
Jatin Sharma
Vidya Rajendran
Rituraj Purohit
Sanjay Kumar

Frontiers in Medicine

doi 10.3389/fmed.2021.684020

7,020 views
56 citations

Original Research

Published on 26 May 2021

MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy

in Precision Medicine

Xing Niu
Biying Huang
Xue Qiao
Jinwen Liu
Lijie Chen
Ming Zhong

Frontiers in Medicine

doi 10.3389/fmed.2021.670188

3,622 views
21 citations

Original Research

Published on 24 May 2021

Potential Prognostic Immune Biomarkers of Overall Survival in Ovarian Cancer Through Comprehensive Bioinformatics Analysis: A Novel Artificial Intelligence Survival Prediction System

in Precision Medicine

Tingshan He
Liwen Huang
Jing Li
Peng Wang
Zhiqiao Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.587496

6,241 views
12 citations

Original Research

Published on 24 May 2021

Exosomal Circular RNA RNA-seq Profiling and the Carcinogenic Role of Exosomal circ-CYP24A1 in Cutaneous Squamous Cell Carcinoma

in Precision Medicine

Zheng Zhang
Hao Guo
Wenjia Yang
Jiuhong Li

Frontiers in Medicine

doi 10.3389/fmed.2021.675842

5,216 views
21 citations

795 articles

articles

Obesity and Dose of Anti-cancer Therapy: Are We Sure to Be on the Right Track in the Precision Medicine Era?

The Concentration of Large Extracellular Vesicles Differentiates Early Septic Shock From Infection

Non-invasive Urine Test for Molecular Classification of Clinical Significance in Newly Diagnosed Prostate Cancer Patients

Novel MYO1D Missense Variant Identified Through Whole Exome Sequencing and Computational Biology Analysis Expands the Spectrum of Causal Genes of Laterality Defects

Molecular Characteristics, Clinical Implication, and Cancer Immunity Interactions of Pyroptosis-Related Genes in Breast Cancer

Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

Multi-Trait Genomic Risk Stratification for Type 2 Diabetes

Role of Immune Cell-Specific Hypermethylation Signatures in Classification and Risk Stratification of Breast Cancer

Identification of Key Genes and Pathways in Persistent Hyperplastic Primary Vitreous of the Eye Using Bioinformatic Analysis

Isoflurane Suppresses Proliferation, Migration, and Invasion and Facilitates Apoptosis in Colorectal Cancer Cells Through Targeting miR-216

m6A RNA Methylation Regulator YTHDF1 Correlated With Immune Microenvironment Predicts Clinical Outcomes and Therapeutic Efficacy in Breast Cancer

Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss

rs12537 Is a Novel Susceptibility SNP Associated With Estrogen Receptor Positive Breast Cancer in Chinese Han Population

Legal Challenges in Precision Medicine: What Duties Arising From Genetic and Genomic Testing Does a Physician Owe to Patients?

Extracellular Vesicles: A Novel Opportunity for Precision Medicine in Respiratory Diseases

A Novel RNA-Binding Protein Signature to Predict Clinical Outcomes and Guide Clinical Therapy in Gastric Cancer

The “Slow Horse Racing Effect” on Lung Function in Adult Life in Chronic Obstructive Pulmonary Disease Associated to Biomass Exposure

Saudi Familial Hypercholesterolemia Patients With Rare LDLR Stop Gain Variant Showed Variable Clinical Phenotype and Resistance to Multiple Drug Regimen

FABP5, a Novel Immune-Related mRNA Prognostic Marker and a Target of Immunotherapy for Multiple Myeloma

Long Non-coding RNA SNHG12, a New Therapeutic Target, Regulates miR-199a-5p/Klotho to Promote the Growth and Metastasis of Intrahepatic Cholangiocarcinoma Cells

Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2

MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy

Potential Prognostic Immune Biomarkers of Overall Survival in Ovarian Cancer Through Comprehensive Bioinformatics Analysis: A Novel Artificial Intelligence Survival Prediction System

Exosomal Circular RNA RNA-seq Profiling and the Carcinogenic Role of Exosomal circ-CYP24A1 in Cutaneous Squamous Cell Carcinoma