Frontiers in Medicine | Precision Medicine

Original Research

Published on 26 Sep 2025

Comparative analysis of deep learning and radiomics models in predicting hepatocellular carcinoma differentiation via ultrasound

in Precision Medicine

Luohang Xu
Yanhua Huang
Hong Fu
Jianhua Yu
Baochun Lu
Yalan Zheng
Jiaxuan Qian
Hongwei Qian

Frontiers in Medicine

doi 10.3389/fmed.2025.1685725

1,455 views

Original Research

Published on 26 Sep 2025

Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients

in Precision Medicine

Hadiah Bassam Al Mahdi
Noor Ahmad Shaik
Zuhier Awan
Hussam Daghistani
Faisal Alandejani
Kawthar Saad Alghamdi
Ahmad A. Obaid
Rawabi Zahed
Reem Nabil Hassan
Sherif Edris

Frontiers in Medicine

doi 10.3389/fmed.2025.1670282

1,883 views

Brief Research Report

Published on 24 Sep 2025

Exploring the binding sites of VRT534 at Cx26 as a putative chemical chaperone for targeted treatment of hereditary hearing disorders

in Precision Medicine

Jennifer Harre
Dahua Wang
Athanasia Warnecke
Carsten Zeilinger

Frontiers in Medicine

doi 10.3389/fmed.2025.1607598

1,132 views

Original Research

Published on 22 Sep 2025

Cyclobenzaprine-related adverse events: a comprehensive pharmacovigilance analysis using the FDA Adverse Event Reporting System

in Precision Medicine

Jiakuan Tu
Chaoxiang Zhang
Shuihua Xie
Jianhua He
Hao Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1574395

2,852 views

Original Research

Published on 22 Sep 2025

TP53 expression in PCAT in coronary artery disease combined with type 2 diabetes mellitus and its correlation with CCTA radiomic features: novel imaging biomarkers

in Precision Medicine

Haicheng Qi
Yahui Hu
Yan Li
Xiumei Li
Yan Xing

Frontiers in Medicine

doi 10.3389/fmed.2025.1626390

1,320 views

Original Research

Published on 18 Sep 2025

A cascaded clinical-ultrasound-biochemical model for precise prediction before thyroid nodule fine-needle aspiration biopsy

in Precision Medicine

Shuhang Gao
Bojia Liu
Mengying Tong
Yalin Zhu
Lina Wang
Linyao Du
Chang Shi
Mei Han
Ying Che

Frontiers in Medicine

doi 10.3389/fmed.2025.1641266

1,055 views

Original Research

Published on 16 Sep 2025

Effectiveness and safety of electroacupuncture in female overactive bladder: a randomized controlled trial investigating sacral and tibial nerve modulation

in Precision Medicine

Zilong Tan
Mengdi Ding
Junru Li
Ran Luo
Jianwu Shen

Frontiers in Medicine

doi 10.3389/fmed.2025.1579276

1,922 views

Review

Published on 15 Sep 2025

The microbiome as a therapeutic co-driver in melanoma immuno-oncology

in Precision Medicine

Jhommara Bautista
Jaime Andrés Villegas-Chávez
Doménica Bunces-Larco
Rafael Martín-Aguilera
Andrés López-Cortés

Frontiers in Medicine

doi 10.3389/fmed.2025.1673880

3,468 views
3 citations

Original Research

Published on 11 Sep 2025

Machine learning prediction of post-CABG atrial fibrillation using clinical and pharmacogenomic biomarkers

in Precision Medicine

Lei Hua
Jingxian Han
Siqi Zhang
Zhiying Li
Hui Qiao
Bin Yang
Xiangguang Meng

Frontiers in Medicine

doi 10.3389/fmed.2025.1650700

2,033 views
1 citation

Original Research

Published on 11 Sep 2025

Prognostic assessment and intelligent prediction system for breast reduction surgery using improved swarm intelligence optimization

in Precision Medicine

Zhiwei Cui
Zhen Liang
Chaohua Liu
Yongjun Chen
Na Wang
Bingyang Liu
Lei Guo
Baoqiang Song

Frontiers in Medicine

doi 10.3389/fmed.2025.1653201

1,379 views

Original Research

Published on 10 Sep 2025

MPVT+: a noise-robust training framework for automatic liver tumor segmentation with noisy labels

in Precision Medicine

Xuan Cheng
Haoxiang Tian
Jiajun Zhou
Tianshu Xie
HaiGang Gong
Ming Liu
Yi Wei
Wei Lu

Frontiers in Medicine

doi 10.3389/fmed.2025.1653865

1,952 views

Original Research

Published on 10 Sep 2025

Advanced supervised machine learning methods for precise diabetes mellitus prediction using feature selection

in Precision Medicine

Gufran Ahmad Ansari
Salliah Shafi
Mohd Dilshad Ansari
Azhar Shadab

Frontiers in Medicine

doi 10.3389/fmed.2025.1620268

2,942 views

Original Research

Published on 09 Sep 2025

Development and internal validation of a mammography-based model fusing clinical, radiomics, and deep learning models for sentinel lymph node metastasis prediction in breast cancer

in Precision Medicine

Xingyuan Liu
Ye Ruan
Siwei Cao
Mingming Zhao
Zhongxing Shi
Yantong Jin
Yang Wang
Bo Gao

Frontiers in Medicine

doi 10.3389/fmed.2025.1659422

1,564 views

Original Research

Published on 09 Sep 2025

An MRI based histogram oriented gradient and deep learning approach for accurate classification of mild cognitive impairment and Alzheimer’s disease

in Precision Medicine

Arunnehru J.
Shakir Khan
Anwar Basha H.
Abdullah M. Albarrak
Aleem Ali

Frontiers in Medicine

doi 10.3389/fmed.2025.1529761

1,762 views

Original Research

Published on 09 Sep 2025

The clinical value of CT and MRI in preoperative TNM staging of esophageal cancer

in Precision Medicine

Weijun Zhao
Jing Huang
Yukun Chen
Jingjing Lu
Wentao Hu

Frontiers in Medicine

doi 10.3389/fmed.2025.1637764

1,509 views

Original Research

Published on 09 Sep 2025

Detecting HER2-positive circulating tumor cells in gastric cancer using a flow cytometry-based approach

in Precision Medicine

Jan-Mou Lee
Chia-Chun Tu
Chih-Hao Fang
Shian-Ren Lin
Shiu-Lan Wang
Wan-Yu Lai
Po-Wei Tseng
Wan-En Liao
Li-Yun Huang
Yee Chao

Frontiers in Medicine

doi 10.3389/fmed.2025.1672955

1,601 views

Original Research

Published on 09 Sep 2025

Severity assessment of COVID-19 disease: radiological visual score versus automated quantitative CT parameters using a pneumonia analysis algorithm

in Precision Medicine

Dario Baldi
Bruna Punzo
Andrea Colacino
Marco Aiello
Monica Franzese
Ludovico La Grutta
Luca Saba
Eduardo Bossone
Emanuela Passaro
Cesare Mantini

Frontiers in Medicine

doi 10.3389/fmed.2025.1606771

1,104 views

Original Research

Published on 08 Sep 2025

The 6-min walk test in transthyretin cardiac amyloidosis: prognostic utility put to the real-world test

in Precision Medicine

Michael Poledniczek
Anna Grubmüller
Christina Kronberger
Robin Willixhofer
Nikita Ermolaev
René Rettl
Christina Binder
Luciana Camuz Ligios
Mahshid Eslami
Bernhard Gregshammer

Frontiers in Medicine

doi 10.3389/fmed.2025.1639586

1,534 views

Opinion

Published on 08 Sep 2025

The promise of artificial intelligence-assisted radiotherapy for prostate cancer in Morocco: a transformational opportunity

in Precision Medicine

Fadila Kouhen
Meryem Naciri
Hanae El Gouache
Nadia Errafiy
Abdelhak Maghous

Frontiers in Medicine

doi 10.3389/fmed.2025.1577034

1,956 views
1 citation

Original Research

Published on 08 Sep 2025

AI-based integration of ECG biomarkers for assessing cardiac risk in type 2 diabetes mellitus with comorbid conditions for patient stratification

in Precision Medicine

Symeon Savvopoulos
Haralampos Hatzikirou
Herbert F. Jelinek

Frontiers in Medicine

doi 10.3389/fmed.2025.1646495

1,656 views

Review

Published on 08 Sep 2025

The association of artificial sweeteners intake and risk of cancer: an umbrella meta-analysis

in Precision Medicine

Ahmed Abu-Zaid
Emad Kutbi
Nawal Alshammari
Abdullah Nasser AlJurayyan
Heba M. Adly
Saleh A. K. Saleh
Saeed Baradwan
Madiha Jamal
Feham Peer-Zada
Shaimaa Mohamed

Frontiers in Medicine

doi 10.3389/fmed.2025.1647178

6,361 views

Review

Published on 04 Sep 2025

The impact of Panx1 on inflammation, immunity, and cancer: a comprehensive review

in Precision Medicine

Francisco J. Bravo
Javier Mena
Ángel Mejía Reyes
Carolina Schäfer
Nelly Núñez-Rojas
Cristopher Blamey-Fredes
Claudio Acuña-Castillo
Carlos Barrera-Avalos

Frontiers in Medicine

doi 10.3389/fmed.2025.1572418

2,167 views

Original Research

Published on 03 Sep 2025

Combining PCR to detect junction fragments and deleted exons in the prenatal diagnosis of BMD can effectively identify maternal cell contamination

in Precision Medicine

Lidan Cai
Wei Li
Min Zhong

Frontiers in Medicine

doi 10.3389/fmed.2025.1599498

1,001 views

Original Research

Published on 02 Sep 2025

Intelligent Alzheimer's diagnosis and disability assessment: robust medical imaging analysis using ensemble learning with ResNet-50 and EfficientNet-B3

in Precision Medicine

Arpanpreet Kaur
Fehaid Salem Alshammari
Ateeq Ur Rehman
Salil Bharany

Frontiers in Medicine

doi 10.3389/fmed.2025.1619228

1,674 views

739 articles

articles

Comparative analysis of deep learning and radiomics models in predicting hepatocellular carcinoma differentiation via ultrasound

Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients

Exploring the binding sites of VRT534 at Cx26 as a putative chemical chaperone for targeted treatment of hereditary hearing disorders

Cyclobenzaprine-related adverse events: a comprehensive pharmacovigilance analysis using the FDA Adverse Event Reporting System

TP53 expression in PCAT in coronary artery disease combined with type 2 diabetes mellitus and its correlation with CCTA radiomic features: novel imaging biomarkers

A cascaded clinical-ultrasound-biochemical model for precise prediction before thyroid nodule fine-needle aspiration biopsy

Effectiveness and safety of electroacupuncture in female overactive bladder: a randomized controlled trial investigating sacral and tibial nerve modulation

The microbiome as a therapeutic co-driver in melanoma immuno-oncology

Machine learning prediction of post-CABG atrial fibrillation using clinical and pharmacogenomic biomarkers

Prognostic assessment and intelligent prediction system for breast reduction surgery using improved swarm intelligence optimization

MPVT+: a noise-robust training framework for automatic liver tumor segmentation with noisy labels

Advanced supervised machine learning methods for precise diabetes mellitus prediction using feature selection

Development and internal validation of a mammography-based model fusing clinical, radiomics, and deep learning models for sentinel lymph node metastasis prediction in breast cancer

An MRI based histogram oriented gradient and deep learning approach for accurate classification of mild cognitive impairment and Alzheimer’s disease

The clinical value of CT and MRI in preoperative TNM staging of esophageal cancer

Detecting HER2-positive circulating tumor cells in gastric cancer using a flow cytometry-based approach

Severity assessment of COVID-19 disease: radiological visual score versus automated quantitative CT parameters using a pneumonia analysis algorithm

The 6-min walk test in transthyretin cardiac amyloidosis: prognostic utility put to the real-world test

The promise of artificial intelligence-assisted radiotherapy for prostate cancer in Morocco: a transformational opportunity

AI-based integration of ECG biomarkers for assessing cardiac risk in type 2 diabetes mellitus with comorbid conditions for patient stratification

The association of artificial sweeteners intake and risk of cancer: an umbrella meta-analysis

The impact of Panx1 on inflammation, immunity, and cancer: a comprehensive review

Combining PCR to detect junction fragments and deleted exons in the prenatal diagnosis of BMD can effectively identify maternal cell contamination

Intelligent Alzheimer's diagnosis and disability assessment: robust medical imaging analysis using ensemble learning with ResNet-50 and EfficientNet-B3