Frontiers in Medicine | Regulatory Science

Perspective

Published on 05 Nov 2025

Herbal medicines adulteration with erectile dysfunction pharmaceuticals in sub-Saharan Africa: call to strengthen regulatory measures

in Regulatory Science

Kampadilemba Ouoba
Daniel Dori
Adela Ashie
Issiaka Soulama
Rasmané Semdé

Frontiers in Medicine

doi 10.3389/fmed.2025.1694833

1,414 views

Original Research

Published on 31 Oct 2025

Considerations on the implementation of DCT: a SCAT-based analysis of fact-finding interviews in Europe and the United States, with implications for regions newly adopting DCT, including Japan

in Regulatory Science

Hiroyuki Taruno
Koji Ikeda
Marika Oikawa
Takahiro Sato
Yuka Suzuki
Mayumi Shikano

Frontiers in Medicine

doi 10.3389/fmed.2025.1521135

1,404 views

Original Research

Published on 31 Oct 2025

Reducing misdiagnosis in AI-driven medical diagnostics: a multidimensional framework for technical, ethical, and policy solutions

in Regulatory Science

Yue Li
Xin Yi
Jia Fu
Yujing Yang
ChuJie Duan
Jun Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1594450

2,880 views

Policy and Practice Reviews

Published on 23 Oct 2025

Early access disparities in innovative therapies across the US, EU, China, and Japan

in Regulatory Science

Sanae Akodad
Michel Goldman
Hilde Stevens

Frontiers in Medicine

doi 10.3389/fmed.2025.1642882

3,014 views

Editorial

Published on 20 Oct 2025

Editorial: Reviews in: regulatory science 2024-2025

in Regulatory Science

Mette Due Theilade Thomsen
Lisbeth Ehlert Knudsen

Frontiers in Medicine

doi 10.3389/fmed.2025.1705977

2,603 views

Correction

Published on 17 Oct 2025

Correction: Harnessing the promises of cell therapy, gene therapy, and regenerative medicine in Québec, Canada

in Regulatory Science

Jean-Sébastien Delisle
Diane Fournier
Kim Santerre
Samuel Rochette
Ma'n H. Zawati
Maude Dumont-Lagacé
Simon Turcotte
Jason Robert Guertin
Patrick Vermette
Jacques P. Tremblay

Frontiers in Medicine

doi 10.3389/fmed.2025.1710876

1,056 views

Policy and Practice Reviews

Published on 16 Oct 2025

Reimagining drug regulation in the age of AI: a framework for the AI-enabled Ecosystem for Therapeutics

in Regulatory Science

Rominder Singh
Karen Zhou
Jared R. Auclair

Frontiers in Medicine

doi 10.3389/fmed.2025.1679611

3,339 views
1 citation

Original Research

Published on 15 Oct 2025

A model structure for describing uncertainties in benefit-risk assessment of oncology drug applications

in Regulatory Science

Nikolaos Zafiropoulos
Francesco Pignatti
Andreas Kouroumalis
Lorenzo Guizzaro
Dominik Karres
Pierre Demolis
Olli Tenhunen
Rosanne Janssens
Anne Taams
Lourens T. Bloem

Frontiers in Medicine

doi 10.3389/fmed.2025.1589578

2,855 views

Original Research

Published on 10 Oct 2025

A real-world data analysis of piroxicam in the FDA Adverse Event Reporting System (FAERS) database

in Regulatory Science

Yanhe Wang
Qiuhong Kong

Frontiers in Medicine

doi 10.3389/fmed.2025.1687088

1,359 views

Perspective

Published on 09 Oct 2025

The regulatory and scientific context in the study of the medicinal use of cannabis in Peru

in Regulatory Science

Pedro Wong-Salgado
Jeel Moya-Salazar
Hans Contreras-Pulache
Claudio Pardo-Villarroel

Frontiers in Medicine

doi 10.3389/fmed.2025.1598227

1,659 views

Systematic Review

Published on 02 Oct 2025

Concentration of propolis as a storage medium for avulsed teeth: a systematic review

in Regulatory Science

Chaya Chhabra
Kumar Gaurav Chhabra
Seemadevi Thangeswaran
Shraddha Shere

Frontiers in Medicine

doi 10.3389/fmed.2025.1583113

1,581 views

Original Research

Published on 26 Sep 2025

Scientific and regulatory progress in advancing paediatric oncology drug development in the EU and in the US

in Regulatory Science

Giorgio Reggiardo
Alessandra Natale
Nicola Santoro
Viviana Giannuzzi
Claudia Pansieri
Mariagrazia Felisi
Donato Bonifazi
Adriana Ceci

Frontiers in Medicine

doi 10.3389/fmed.2025.1642279

1,713 views

Original Research

Published on 23 Sep 2025

Harmonizing health: a global analysis of pharmaceutical regulatory activities by international regulatory organizations

in Regulatory Science

Agnes Dangy-Caye
Alice Mousset
Adem Kermad
Louise Bouché-Bazerolle
Magda Bujar
Maria-Lucia De Lucia
Neil McAuslane
Rebecca Lumsden

Frontiers in Medicine

doi 10.3389/fmed.2025.1636269

8,834 views
1 citation

Original Research

Published on 22 Sep 2025

Barriers and determinants of over-the-counter antibiotic sales de-escalation: perspectives of community pharmacists in Aseer, Saudi Arabia

in Regulatory Science

Sultan M. Alshahrani
Sirajudeen Shaik Alavudeen

Frontiers in Medicine

doi 10.3389/fmed.2025.1677246

1,942 views

Original Research

Published on 17 Sep 2025

Performance analysis of EAC joint GMP inspections (2016–2022): a pathway to strengthening regulatory systems and building capacity in Africa’s less resourced authorities

in Regulatory Science

Jane Mashingia
Noel Aineplan
Kari Clase
Steven Bryn
Zita Ekeocha

Frontiers in Medicine

doi 10.3389/fmed.2025.1644446

1,571 views

Review

Published on 15 Sep 2025

Transforming the interrelated nature of human psychoneuroendocrine health and endocrine disrupting compounds in our planet’s water: from Wilhelm Waldeyer’s neuron theory to an artificial intelligence extension of the human body?

in Regulatory Science

Sophie Schweizer-Schubert
Götz von Waldeyer-Hartz
Susann-Elisabeth Schütze
Daniel Mahringer
Aki Sebastian Ruhl
Markus Graf
Jochen Kuckelkorn

Frontiers in Medicine

doi 10.3389/fmed.2025.1583203

1,732 views

Systematic Review

Published on 11 Sep 2025

Visual analysis of quality management in Chinese drug clinical trials based on CiteSpace and COOC

in Regulatory Science

Jiayan Xia
Xuemei Ning
Lamei Jiang
Peipei Li
Jie Huang
Wenxiu Jiang
Wen Li
Cheng Wang
Linsha Zheng
Ting Jiang

Frontiers in Medicine

doi 10.3389/fmed.2025.1600915

1,899 views

Original Research

Published on 11 Sep 2025

Preparing for the European Health Data Space: an open-source compiler for fast, transparent, and portable health data transformations

in Regulatory Science

Stefan Beyer
Nikola Tanjga
Gabriel Kleinoscheg
Dieter Hayn
Klaus Donsa
Karl Kreiner
Günter Schreier

Frontiers in Medicine

doi 10.3389/fmed.2025.1661091

1,684 views

Systematic Review

Published on 10 Sep 2025

Societal participation in the development of orphan drugs: a systematic review

in Regulatory Science

Sanae Akodad
Delphine De Smedt
Hilde Stevens

Frontiers in Medicine

doi 10.3389/fmed.2025.1653304

1,953 views

Policy Brief

Published on 09 Sep 2025

Accelerating European electronic health record exchange format (EEHRxF) implementation across Europe: a policy perspective

in Regulatory Science

Nathan da Silva Carvalho
Alexia Papadimitriou
Robert Stegwee
Hans Gille
Michael Strübin
Christophe Maes
Giorgio Cangioli
Catherine Chronaki

Frontiers in Medicine

doi 10.3389/fmed.2025.1648170

2,154 views

Correction

Published on 05 Sep 2025

Correction: Summary of the best evidence for the use of antiseptics at various surgical sites to prevent postoperative infections

in Regulatory Science

Frontiers Production Office

Frontiers in Medicine

doi 10.3389/fmed.2025.1698325

901 views

Original Research

Published on 04 Sep 2025

Lessons from Ethiopian pharmaceutical regulation: a risk-based approach to overcome challenges and unlock opportunities

in Regulatory Science

Hassen Kebede Hassen
Yesuneh Tefera Mekasha
Addisu Afrassa Tegegne
Yildiz Ozalp

Frontiers in Medicine

doi 10.3389/fmed.2025.1484649

3,313 views

Perspective

Published on 02 Sep 2025

How life-cycle real-world evidence can bridge evidentiary gaps in precision oncology

in Regulatory Science

Emanuel Krebs
Deirdre Weymann
Tania Bubela
Dean A. Regier

Frontiers in Medicine

doi 10.3389/fmed.2025.1563950

2,058 views

Editorial

Published on 29 Aug 2025

Editorial: Errors and biases in modern healthcare: public health, medico-legal and risk management aspects

in Regulatory Science

Simone Grassi
Francesco Ausania
Davide Ferorelli
Francesco De Micco

Frontiers in Medicine

doi 10.3389/fmed.2025.1676522

1,139 views

504 articles

articles

Herbal medicines adulteration with erectile dysfunction pharmaceuticals in sub-Saharan Africa: call to strengthen regulatory measures

Considerations on the implementation of DCT: a SCAT-based analysis of fact-finding interviews in Europe and the United States, with implications for regions newly adopting DCT, including Japan

Reducing misdiagnosis in AI-driven medical diagnostics: a multidimensional framework for technical, ethical, and policy solutions

Early access disparities in innovative therapies across the US, EU, China, and Japan

Editorial: Reviews in: regulatory science 2024-2025

Correction: Harnessing the promises of cell therapy, gene therapy, and regenerative medicine in Québec, Canada

Reimagining drug regulation in the age of AI: a framework for the AI-enabled Ecosystem for Therapeutics

A model structure for describing uncertainties in benefit-risk assessment of oncology drug applications

A real-world data analysis of piroxicam in the FDA Adverse Event Reporting System (FAERS) database

The regulatory and scientific context in the study of the medicinal use of cannabis in Peru

Concentration of propolis as a storage medium for avulsed teeth: a systematic review

Scientific and regulatory progress in advancing paediatric oncology drug development in the EU and in the US

Harmonizing health: a global analysis of pharmaceutical regulatory activities by international regulatory organizations

Barriers and determinants of over-the-counter antibiotic sales de-escalation: perspectives of community pharmacists in Aseer, Saudi Arabia

Performance analysis of EAC joint GMP inspections (2016–2022): a pathway to strengthening regulatory systems and building capacity in Africa’s less resourced authorities

Transforming the interrelated nature of human psychoneuroendocrine health and endocrine disrupting compounds in our planet’s water: from Wilhelm Waldeyer’s neuron theory to an artificial intelligence extension of the human body?

Visual analysis of quality management in Chinese drug clinical trials based on CiteSpace and COOC

Preparing for the European Health Data Space: an open-source compiler for fast, transparent, and portable health data transformations

Societal participation in the development of orphan drugs: a systematic review

Accelerating European electronic health record exchange format (EEHRxF) implementation across Europe: a policy perspective

Correction: Summary of the best evidence for the use of antiseptics at various surgical sites to prevent postoperative infections

Lessons from Ethiopian pharmaceutical regulation: a risk-based approach to overcome challenges and unlock opportunities

How life-cycle real-world evidence can bridge evidentiary gaps in precision oncology

Editorial: Errors and biases in modern healthcare: public health, medico-legal and risk management aspects