Frontiers in Medicine | Translational Medicine

Review

Published on 04 Dec 2025

Beyond the hype: re-evaluating efficacy metrics and modeling rigor for MSC-EVs-based therapy in acute brain injury

in Translational Medicine

Fating Zhou
Hongxia Wang
Xiaodan Zhu
Rui Huang
Xuemei Jiang
Haizhen Duan
Yu Ma
Shanmu Ai

Frontiers in Medicine

doi 10.3389/fmed.2025.1654429

854 views

Original Research

Accepted on 03 Dec 2025

Effects and underlying mechanism of platelet-rich plasma gel on vaginal microecology and stump healing

in Translational Medicine

Mingyang Wang
Yunbi Peng
Li Zhou
Hong Liu
Xiaofeng Zou
Zhiliang Wang

Frontiers in Medicine

Original Research

Accepted on 03 Dec 2025

Genotype-phenotype correlations in 18 European patients with heterozygous KIF1A variants; Key Considerations for Assessing KIF1A Variant Causality

in Translational Medicine

Anna Uhrova Meszarosova
Elea Galiart
Petra Lassutova
Konstantinos Kolokotronis
Benjamin Seidl
Alena Musilova
Anna Peckova
Alena Takacsova
Emilie Vyhnalkova
Dagmar Grecmalova

Frontiers in Medicine

131 views

Original Research

Accepted on 02 Dec 2025

Distinct Clinical and Inflammatory Signatures in Anterior vs. Posterior Circulation Strokes

in Translational Medicine

Chen Hanna Ryder
Carmit Gal
Gili Barkay
Michael Zagorodniuk
Dan Paz
Galina Keigler
Einav Levy
Yori Gidron
Mohammad Ebrahim Naffaa
Samih Badarny

Frontiers in Medicine

111 views

Original Research

Published on 02 Dec 2025

Preliminary study on the influencing factors of Young’s modulus of viscoelastic model detected by shear wave elasticity

in Translational Medicine

Aifen Wu
Maosheng Xu
Shijia Wang
Xiu Chen
Yi Zhou
Bin Zhou
Chunpeng Zou
Yanhua Huang
Ying Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1684745

501 views

Mini Review

Accepted on 01 Dec 2025

The potential of antimicrobial peptides to treat oral infections and cancer

in Translational Medicine

Ana Emilia Carvalho de Paula
Carla Silva Siqueira
Esteban Nicolás Lorenzón

Frontiers in Medicine

154 views

Systematic Review

Published on 01 Dec 2025

Impact of different endocrine therapies on bone mineral density and fracture risk in postmenopausal breast cancer patients: a meta-analysis

in Translational Medicine

Haoran Qu
Juntao Wang
Zhekun Wang
Bingjie Guan
Yuling Zheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1665389

804 views

Original Research

Published on 28 Nov 2025

Recovery efficiency and functional characterization of T cells and NK cells from leukocyte filters

in Translational Medicine

Liyan Sun
Ran Li
Siqi Cai
Songxing Wang
Jinfeng Zeng

Frontiers in Medicine

doi 10.3389/fmed.2025.1681146

527 views

Review

Published on 28 Nov 2025

Recent advancements in smart responsive tissue adhesives for medical applications

in Translational Medicine

Shiqi Lin
Qiang Jin
Ji Wang
Sufan Wu
Yi Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1696667

784 views

Perspective

Published on 28 Nov 2025

Restoring trust in vaccination: listening to patients and acknowledging Post-Acute COVID Vaccine Syndrome

in Translational Medicine

Matthew Halma
Joseph Varon

Frontiers in Medicine

doi 10.3389/fmed.2025.1688170

4,460 views

Hypothesis and Theory

Published on 26 Nov 2025

How exosomal platelet-derived miRNAs can lead to spontaneous osteoclastogenesis in osteoporosis: a new mechanistic viewpoint

in Translational Medicine

Francesca Salamanna
Gianluca Giavaresi
Alberto Di Martino
Agostino Gaudio
Fabiana Nucera
Cesare Faldini
Milena Fini

Frontiers in Medicine

doi 10.3389/fmed.2025.1720672

746 views

Original Research

Published on 26 Nov 2025

Compare the prognosis of pancreatic cancer patients with different treatment modalities and use machine learning methods to build predictive models

in Translational Medicine

Lingling Fan
Shujing Kong
Yizhou Deng
Yunfan Wang
Xiancheng Yan
Chao Jiang
Li Tao
Weimin Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1629324

782 views

Review

Published on 26 Nov 2025

Reprogramming prostate cancer through the microbiome

in Translational Medicine

Jhommara Bautista
Walter D. Cardona-Maya
Kelly Gancino-Guevara
Andrés López-Cortés

Frontiers in Medicine

doi 10.3389/fmed.2025.1690498

1,321 views

Original Research

Accepted on 25 Nov 2025

Multi-Targeted Inhibition of NF-κB Signaling Underlies the Anti-Osteoarthritic Effects of BGJXF and Its Key Component Dehydrocorydaline

in Translational Medicine

Jingyu Shen
Zhenpeng Bin
Yunfu Shen
Fang Xie
Xincheng Zhang
Xuyi Tan
Hui Xu

Frontiers in Medicine

113 views

Original Research

Published on 24 Nov 2025

Interferon-induced transmembrane proteins as biomarkers for assessing the diagnosis and severity of coronary artery disease and acute myocardial infarction

in Translational Medicine

Qingyan Huang
Xiaoqi Zheng
Yuhong Gan
Shaobin Zhi
Junxing Zhu
Xiaoyan Tang
Mingfeng Huang
Qionghui Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1645725

685 views

Opinion

Published on 24 Nov 2025

Can dogs sniff out cancer? Exploring the role of medical detection dogs in Hong Kong's early diagnosis strategies

in Translational Medicine

Timothy Quan Lo
Bryden Chung Bun Tsui
Kei Shing Ng
Simon Ching Lam

Frontiers in Medicine

doi 10.3389/fmed.2025.1644112

949 views

Review

Published on 24 Nov 2025

Lung cancer and the Gut-microbiota-lung Axis: emerging evidence and potential clinical implications

in Translational Medicine

Li Liu
Li Yang
Hongdu Zhang
Hongmin Li
Tianlu Shang
Lihan Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1655780

1,226 views

Original Research

Published on 21 Nov 2025

Exploring the role of febuxostat’s drug target XOR in erectile dysfunction: insights from human genetics and rat models

in Translational Medicine

Zhibin Chen
Yuqi Li
Chunyang Meng
Xiaorong Li
Huan Liao
Xiong Li
Yang Zeng
Xu Li
Tao Zhou
Qingfu Deng

Frontiers in Medicine

doi 10.3389/fmed.2025.1674086

835 views

Original Research

Accepted on 19 Nov 2025

Towards Brain-Computer Interface Motor Rehabilitation for People with Multiple Sclerosis

in Translational Medicine

Marc Sebastián-Romagosa
Woosang Cho
Rupert Ortner
Sebastian Sieghartsleitner
Michael Guger
Tim J Von Oertzen
Sven Guenther Meuth
Steven Laureys
Brendan Z Allison
Christoph Guger

Frontiers in Medicine

236 views

Brief Research Report

Published on 19 Nov 2025

Optimization of concentration-directed blood purification therapy in the management of diquat poisoning

in Translational Medicine

Weiwei Qian
Xuxin Xie
Bofu Liu
Chengtong He
Yu Cao

Frontiers in Medicine

doi 10.3389/fmed.2025.1713595

529 views

Original Research

Accepted on 18 Nov 2025

A clinical prediction model for schizophrenia based on machine learning algorithms

in Translational Medicine

Weifeng Jin
Shuzi Chen
Qiong Gao
Dan Li
Wei Lu
Mengxia Wang
Qing Chen
Ping Lin

Frontiers in Medicine

133 views

Editorial

Published on 18 Nov 2025

Editorial: Advancements in translational models: bridging basic infection research and clinical applications

in Translational Medicine

Artur Schmidtchen
Aftab Nadeem
Haris Mirza
Karl Wallblom
Deepak Bushan Raina
Oonagh Shannon
Jitka Petrlova
Manoj Puthia

Frontiers in Medicine

doi 10.3389/fmed.2025.1730195

749 views

Review

Published on 17 Nov 2025

Recent advances in metal-organic frameworks for therapeutic applications in periodontitis

in Translational Medicine

Jiaqi Chen
Yang Bai
Yude Ding
Linhong Wang
Wentao Zhang
Fan Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1706849

893 views

Original Research

Accepted on 12 Nov 2025

Factors Influencing Therapeutic Efficacy of Non-Lactational Mastitis Based on Hematological Inflammatory Markers and Establishment of a Predictive Model

in Translational Medicine

Jinjuan Peng
Li Li
Lili Fan
Qun Lu

Frontiers in Medicine

181 views

651 articles

articles

Beyond the hype: re-evaluating efficacy metrics and modeling rigor for MSC-EVs-based therapy in acute brain injury

Effects and underlying mechanism of platelet-rich plasma gel on vaginal microecology and stump healing

Genotype-phenotype correlations in 18 European patients with heterozygous KIF1A variants; Key Considerations for Assessing KIF1A Variant Causality

Distinct Clinical and Inflammatory Signatures in Anterior vs. Posterior Circulation Strokes

Preliminary study on the influencing factors of Young’s modulus of viscoelastic model detected by shear wave elasticity

The potential of antimicrobial peptides to treat oral infections and cancer

Impact of different endocrine therapies on bone mineral density and fracture risk in postmenopausal breast cancer patients: a meta-analysis

Recovery efficiency and functional characterization of T cells and NK cells from leukocyte filters

Recent advancements in smart responsive tissue adhesives for medical applications

Restoring trust in vaccination: listening to patients and acknowledging Post-Acute COVID Vaccine Syndrome

How exosomal platelet-derived miRNAs can lead to spontaneous osteoclastogenesis in osteoporosis: a new mechanistic viewpoint

Compare the prognosis of pancreatic cancer patients with different treatment modalities and use machine learning methods to build predictive models

Reprogramming prostate cancer through the microbiome

Multi-Targeted Inhibition of NF-κB Signaling Underlies the Anti-Osteoarthritic Effects of BGJXF and Its Key Component Dehydrocorydaline

Interferon-induced transmembrane proteins as biomarkers for assessing the diagnosis and severity of coronary artery disease and acute myocardial infarction

Can dogs sniff out cancer? Exploring the role of medical detection dogs in Hong Kong's early diagnosis strategies

Lung cancer and the Gut-microbiota-lung Axis: emerging evidence and potential clinical implications

Exploring the role of febuxostat’s drug target XOR in erectile dysfunction: insights from human genetics and rat models

Towards Brain-Computer Interface Motor Rehabilitation for People with Multiple Sclerosis

Optimization of concentration-directed blood purification therapy in the management of diquat poisoning

A clinical prediction model for schizophrenia based on machine learning algorithms

Editorial: Advancements in translational models: bridging basic infection research and clinical applications

Recent advances in metal-organic frameworks for therapeutic applications in periodontitis

Factors Influencing Therapeutic Efficacy of Non-Lactational Mastitis Based on Hematological Inflammatory Markers and Establishment of a Predictive Model