Frontiers in Medicine | Translational Medicine

Original Research

Published on 06 Dec 2021

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways

in Translational Medicine

Lin Hu
Yuyang Wang
Yuzhou Wan
Liang Ma
Tingting Zhao
Ping Li

Frontiers in Medicine

doi 10.3389/fmed.2021.732042

5,693 views
18 citations

Original Research

Published on 03 Dec 2021

A Deep-Learning Pipeline for TSS Coverage Imputation From Shallow Cell-Free DNA Sequencing

in Translational Medicine

Bo-Wei Han
Xu Yang
Shou-Fang Qu
Zhi-Wei Guo
Li-Min Huang
Kun Li
Guo-Jun Ouyang
Geng-Xi Cai
Wei-Wei Xiao
Rong-Tao Weng

Frontiers in Medicine

doi 10.3389/fmed.2021.684238

5,644 views
4 citations

Opinion

Published on 01 Dec 2021

The Striking Need for Age Diverse Pulse Oximeter Databases

in Translational Medicine

Mohamed Elgendi
Richard Ribon Fletcher
Harshit Tomar
John Allen
Rabab Ward
Carlo Menon

Frontiers in Medicine

doi 10.3389/fmed.2021.782422

4,222 views
10 citations

Systematic Review

Published on 01 Dec 2021

ATMP Environmental Exposure Assessment in European Healthcare Settings: A Systematic Review of the Literature

in Translational Medicine

Margaux Damerval
Christine Fagnoni-Legat
Aurélien Louvrier
Sarah Fischer
Samuel Limat
Anne-Laure Clairet
Virginie Nerich
Isabelle Madelaine
Marie Kroemer

Frontiers in Medicine

doi 10.3389/fmed.2021.713047

6,456 views
8 citations

Original Research

Published on 01 Dec 2021

Increase in Plasma Oxidized Phosphatidylcholines (OxPCs) in Patients Presenting With ST-Elevation Myocardial Infarction (STEMI)

in Translational Medicine

Zahra Solati
Arun Surendran
Andrea Edel
Marynia Roznik
David Allen
Amir Ravandi

Frontiers in Medicine

doi 10.3389/fmed.2021.716944

4,471 views
13 citations

Original Research

Published on 29 Nov 2021

Development and Validation of a Deep Learning Algorithm to Automatic Detection of Pituitary Microadenoma From MRI

in Translational Medicine

Qingling Li
Yanhua Zhu
Minglin Chen
Ruomi Guo
Qingyong Hu
Yaxin Lu
Zhenghui Deng
Songqing Deng
Tiecheng Zhang
Huiquan Wen

Frontiers in Medicine

doi 10.3389/fmed.2021.758690

5,528 views
9 citations

Original Research

Published on 26 Nov 2021

Elevated Serum Tenascin-C Predicts Mortality in Critically Ill Patients With Multiple Organ Dysfunction

in Translational Medicine

Yunyu Xu
Nanyang Li
Jiamin Gao
Da Shang
Min Zhang
Xiaoyi Mao
Ruiying Chen
Jianming Zheng
Ying Shan
Mingquan Chen

Frontiers in Medicine

doi 10.3389/fmed.2021.759273

4,016 views
6 citations

Review

Published on 25 Nov 2021

Recent Progress on the Synergistic Antitumor Effect of a Borneol-Modified Nanocarrier Drug Delivery System

in Translational Medicine

Jinxiu Li
Qian Xie
Rong Ma
Yong Li
Jianmei Yuan
Mihong Ren
Hongyan Li
Jiajun Wang
Danni Lu
Zhuo Xu

Frontiers in Medicine

doi 10.3389/fmed.2021.750170

9,421 views
25 citations

Original Research

Published on 25 Nov 2021

Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?

in Translational Medicine

Daniel Gussarow
Agnes Bonifacius
Anne Cossmann
Metodi V. Stankov
Philip Mausberg
Sabine Tischer-Zimmermann
Nina Gödecke
Ulrich Kalinke
Georg M. N. Behrens
Rainer Blasczyk

Frontiers in Medicine

doi 10.3389/fmed.2021.770381

14,248 views
18 citations

Original Research

Published on 25 Nov 2021

β-Hydroxybutyrate Oxidation in Exercise Is Impaired by Low-Carbohydrate and High-Fat Availability

in Translational Medicine

David J. Dearlove
David Holdsworth
Tom Kirk
Leanne Hodson
Evelina Charidemou
Eline Kvalheim
Brianna Stubbs
Andrew Beevers
Julian L. Griffin
Rhys Evans

Frontiers in Medicine

doi 10.3389/fmed.2021.721673

7,102 views
17 citations

Original Research

Published on 25 Nov 2021

Segmentation of Cerebral Small Vessel Diseases-White Matter Hyperintensities Based on a Deep Learning System

in Translational Medicine

Wei Shan
Yunyun Duan
Yu Zheng
Zhenzhou Wu
Shang Wei Chan
Qun Wang
Peiyi Gao
Yaou Liu
Kunlun He
Yongjun Wang

Frontiers in Medicine

doi 10.3389/fmed.2021.681183

4,758 views
7 citations

Original Research

Published on 23 Nov 2021

Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model

in Translational Medicine

Florian Flenkenthaler
Erik Ländström
Bachuki Shashikadze
Mattias Backman
Andreas Blutke
Julia Philippou-Massier
Simone Renner
Martin Hrabe de Angelis
Rüdiger Wanke
Helmut Blum

Frontiers in Medicine

doi 10.3389/fmed.2021.751277

5,811 views
20 citations

Original Research

Published on 23 Nov 2021

Perspectives, Expectations, and Concerns of European Patient Advocates on Advanced Therapy Medicinal Products

in Translational Medicine

Stefano Benvenuti
Chiuhui Mary Wang
Simona Borroni

Frontiers in Medicine

doi 10.3389/fmed.2021.728529

5,080 views
10 citations

Original Research

Published on 19 Nov 2021

MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function

in Translational Medicine

Wei Yan
Yingchun Shen
Jinny Huang
Ling Lu
Qian Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.752223

6,108 views
11 citations

Original Research

Published on 11 Nov 2021

Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification

in Translational Medicine

Yulian Zhang
Qi Wang
Zai Wang
Chuanpeng Zhang
Xiaoli Xu
Jun Xu
Hongxiang Ren
Xu Shao
Xueke Zhen
Li Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.739624

5,609 views
6 citations

Original Research

Published on 08 Nov 2021

Deep Learning-Based Speech Enhancement With a Loss Trading Off the Speech Distortion and the Noise Residue for Cochlear Implants

in Translational Medicine

Yuyong Kang
Nengheng Zheng
Qinglin Meng

Frontiers in Medicine

doi 10.3389/fmed.2021.740123

7,715 views
12 citations

Original Research

Published on 08 Nov 2021

Pre-Consultation System Based on the Artificial Intelligence Has a Better Diagnostic Performance Than the Physicians in the Outpatient Department of Pediatrics

in Translational Medicine

Han Qian
Bin Dong
Jia-jun Yuan
Fan Yin
Zhao Wang
Hai-ning Wang
Han-song Wang
Dan Tian
Wei-hua Li
Bin Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.695185

8,905 views
13 citations

Mini Review

Published on 05 Nov 2021

Crosstalk Between ER Stress, Autophagy and Inflammation

in Translational Medicine

Sandhya Chipurupalli
Unni Samavedam
Nirmal Robinson

Frontiers in Medicine

doi 10.3389/fmed.2021.758311

22,430 views
151 citations

Original Research

Published on 03 Nov 2021

A Clinically-Compatible Workflow for Computer-Aided Assessment of Brain Disease Activity in Multiple Sclerosis Patients

in Translational Medicine

Benoit Combès
Anne Kerbrat
Guillaume Pasquier
Olivier Commowick
Brandon Le Bon
Francesca Galassi
Philippe L'Hostis
Nora El Graoui
Raphael Chouteau
Emmanuel Cordonnier

Frontiers in Medicine

doi 10.3389/fmed.2021.740248

3,668 views
17 citations

Original Research

Published on 03 Nov 2021

Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics

in Translational Medicine

Xiang Xu
Hanlu Li
Qingxia Wei
Xin Li
Yanying Shen
Ge Guo
Yibing Chen
Kunlun He
Chunlei Liu

Frontiers in Medicine

doi 10.3389/fmed.2021.742436

7,429 views
13 citations

Systematic Review

Published on 02 Nov 2021

Analysis of the Status and Trends of Chinese Clinical Practice Guideline Development Between 2010 and 2020: A Systematic Review

in Translational Medicine

Rong Zhang
Si-yu Yan
Yun-yun Wang
Qiao Huang
Xiang-ying Ren
Ran Tan
Yu-qing Deng
Lin-xia Su
Yong-bo Wang
Zheng-rong Zhao

Frontiers in Medicine

doi 10.3389/fmed.2021.758617

7,013 views
14 citations

Original Research

Published on 28 Oct 2021

Preclinical Assessment of Paclitaxel- and Trastuzumab-Delivering Magnetic Nanoparticles Fe3O4 for Treatment and Imaging of HER2-Positive Breast Cancer

in Translational Medicine

Liting Guo
Hongming Zhang
Ping Liu
Tianai Mi
Da Ha
Li Su
Lei Huang
Yan Shi
Jun Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.738775

4,952 views
13 citations

Original Research

Published on 28 Oct 2021

Angiogenesis Pathway in Kidney Renal Clear Cell Carcinoma and Its Prognostic Value for Cancer Risk Prediction

in Translational Medicine

Xiangyu Che
Wenyan Su
Xiaowei Li
Nana Liu
Qifei Wang
Guangzhen Wu

Frontiers in Medicine

doi 10.3389/fmed.2021.731214

4,363 views
9 citations

Original Research

Published on 26 Oct 2021

RESTORE Survey on the Public Perception of Advanced Therapies and ATMPs in Europe—Why the European Union Should Invest More!

in Translational Medicine

Gady Goldsobel
Christoph von Herrath
Stephan Schlickeiser
Nicola Brindle
Frauke Stähler
Petra Reinke
Zami Aberman
Racheli Ofir
Gabriella Dessole
Stefano Benvenuti

Frontiers in Medicine

doi 10.3389/fmed.2021.739987

5,850 views
13 citations