Frontiers in Medicine | Translational Medicine

Original Research

Published on 12 Nov 2025

Identification and validation of novel risk genes for intervertebral disc disorder by integrating large-scale multi-omics analyses and experimental studies

in Translational Medicine

Zhe Zhang
Yu Chen
Qianjin Wang
Zheng Li
Bingyang Dai
Cheng Dong
Zhengya Zhu

Frontiers in Medicine

doi 10.3389/fmed.2025.1698050

1,110 views

Clinical Trial

Published on 11 Nov 2025

Efficacy of Fu’s Subcutaneous Needling for chronic non-specific neck pain and its effect on muscle elasticity: a randomized controlled trial

in Translational Medicine

Zhilin Gu
Ting Zhou
Chunyan Liu
Jiebin Zhu
Yingying Liao

Frontiers in Medicine

doi 10.3389/fmed.2025.1701076

934 views

Original Research

Published on 11 Nov 2025

A Dual-input deep learning architecture for classification and latency estimation in ABR signals

in Translational Medicine

Youssef Darahem
Oguz Yilmaz
Halil B. Saldirim
Berna Mutlu
Hasan F. Ates
Bahadir K. Gunturk

Frontiers in Medicine

doi 10.3389/fmed.2025.1693921

1,130 views

Original Research

Accepted on 10 Nov 2025

Diagnostic Prediction Model for Acute Ischemic Stroke Using Stress Hyperglycemia and Neutrophil-to-Lymphocyte Ratios

in Translational Medicine

Yi Jiang
Chenran Zhang
Chaoping Wang

Frontiers in Medicine

175 views

Original Research

Published on 07 Nov 2025

Influence of different urine preservation methods and addition of preservatives on quantitative detection of 24-h urinary protein

in Translational Medicine

Xinxin Bao
Xiaoye Sun
Haiying Geng
Xiaohua Yuan

Frontiers in Medicine

doi 10.3389/fmed.2025.1661339

1,407 views

Systematic Review

Published on 06 Nov 2025

Mechanical stress-mediated immune and inflammatory regulation: a bibliometric and visualization analysis of mechanoimmunology based on two databases

in Translational Medicine

Jiayuecheng Pang
Yicheng Ma
Hongchao Huang
Jiqing Ma
Yongjun Zheng
Shichu Xiao
Zhaofan Xia

Frontiers in Medicine

doi 10.3389/fmed.2025.1698177

1,800 views

Case Report

Published on 06 Nov 2025

Digit salvage therapy with integrated Chinese and Western medicine: report of case series

in Translational Medicine

Jiaming Cui
Hanbo Wang
Yanlong Yao
Junwei Zong
Ying Gong
Ran Sun
Mingzhi Song

Frontiers in Medicine

doi 10.3389/fmed.2025.1656640

958 views

Case Report

Accepted on 05 Nov 2025

Cold Agglutinin Syndrome in a Patient with Metastatic Breast Cancer: A Case Report

in Translational Medicine

Daniel Bandarra
Beatriz Gosalbez
José Ferreira
Nidia Maltez Cunha
Sara Carvalhal

Frontiers in Medicine

151 views

Original Research

Published on 04 Nov 2025

Biomechanical comparison of five fixation methods in minimally invasive hallux valgus osteotomy: a three-dimensional finite element analysis

in Translational Medicine

Xiaomei Li
Lan Zhang
Jiandong Wang
Yongjun Wang
Guangming Dai
Wei Jiang
Haoyan Zheng
Bo Feng
Weiqing Tian

Frontiers in Medicine

doi 10.3389/fmed.2025.1701147

903 views

Review

Published on 03 Nov 2025

The role of reactive oxygen species-mitophagy regulation in the treatment of osteoarthritis by active Chinese herbal medicine monomers: a review

in Translational Medicine

Runjia Lei
Chaoqing Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1686190

1,115 views

Original Research

Accepted on 30 Oct 2025

A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysisAssociation between smoking, periodontal inflammation, and alveolar bone resorption in chronic periodontitis: a meta-analysis

in Translational Medicine

Bing Li
Li Xia
Cui Liu
Qingqing Zhu
Zhe Chen

Frontiers in Medicine

144 views

Original Research

Published on 30 Oct 2025

Application of composite layered repair system using titanium mesh, bone cement and vacuum sealing drainage for chest wall defect

in Translational Medicine

Gaofeng Liu
Xiaoyong Ding
Qingyuan Li
Xia Chu
Yingbiao Deng
Sujuan Cui
Li Zhou
Chaofeng Xing
Xiaohang Sun
Jie Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1681418

737 views

Original Research

Published on 30 Oct 2025

Targeted metabolomic profiling reveals inflammation–associated longitudinal changes in plasma metabolites following on-pump coronary bypass surgery

in Translational Medicine

Frieder Neu
Max Wacker
Sven Schuchardt
Sam Varghese
George Awad
Fakhar H. Waqas
Jens Wippermann
Frank Pessler
Priya Veluswamy

Frontiers in Medicine

doi 10.3389/fmed.2025.1673132

1,262 views

Original Research

Accepted on 28 Oct 2025

Longitudinal Impact of Radiotherapy on Cardiac Function in Cancer Patients: A Retrospective Cohort Study of Risk Factors and Clinical Outcome

in Translational Medicine

Haiyan Qin
Jianfeng Li
Bo Yang
Rong Li
Rui Wu
Maoying Lan
Yongdong Zhuang

Frontiers in Medicine

294 views

Original Research

Published on 27 Oct 2025

Unraveling the genetic links between obesity or insulin resistance and breast cancer through the impact of CD295 and ITLN1 SNPs with DNA damage in a case-controlled study with bioinformatics analysis

in Translational Medicine

Nadia M. Hamdy
Yasser O. Mosaad
Reham Elshimy
Ahmad A. Hady
Queran Lin
Zayd Jastaniah
Razan Amjad
Huda Altoukhi
Hatim Almarzouki
Ahmed Abdelsamad

Frontiers in Medicine

doi 10.3389/fmed.2025.1703759

1,211 views

Original Research

Published on 27 Oct 2025

Effect of inflammation on neurovascular coupling, microperfusion, and clinical outcomes in ischemic stroke patients: a case series report

in Translational Medicine

Astrid Cancino
Pablo Muñoz
Pablo Cox
Lilian Acevedo
Sebastián Castillo
Aldo Letelier
Alejandro Veloz
Maria Rodriguez-Fernandez
Steren Chabert

Frontiers in Medicine

doi 10.3389/fmed.2025.1665396

948 views

Original Research

Published on 24 Oct 2025

Comprehensive genetic screening of 70 severe adolescent idiopathic scoliosis probands reveals novel pathogenic variants and syndromic associations

in Translational Medicine

Monika Horbacz
Magdalena Koczkowska
Marek Rocławski
Marcin Ceynowa
Piotr Madanecki
Daniil Sarkisyan
Jakub Mieczkowski
Karolina Śledzińska
Jan P. Dumanski
Rafał Pankowski

Frontiers in Medicine

doi 10.3389/fmed.2025.1646415

1,636 views

Original Research

Published on 23 Oct 2025

Automatic measurement of mesenteric vascular and portal vein parameters via PE-NET in the diagnosis of Crohn’s disease

in Translational Medicine

Weize Xu
Liangfang Zheng
Kun Zhang
Bosheng He

Frontiers in Medicine

doi 10.3389/fmed.2025.1634056

1,082 views

Review

Published on 22 Oct 2025

Sinomenine in cerebral ischemia: mechanisms, delivery strategies, and the emerging multifunctional biomaterials of the bone–brain axis

in Translational Medicine

Xiang Li
Xinyi Zhang
Tingyu Wang
Hangyu Li
Yuxuan Li
Jianchun Liu
Yuqi Bai

Frontiers in Medicine

doi 10.3389/fmed.2025.1677685

1,692 views

Original Research

Published on 20 Oct 2025

Imaging of human airways by endoscope-compatible dynamic microscopic optical coherence tomography

in Translational Medicine

Cornelia Holzhausen
Hinnerk Schulz-Hildebrandt
Martin Ahrens
Noah Heldt
Mario Pieper
Heike Biller
Sönke von Weihe
David Ellebrecht
Mustafa Abdo
Stefan Steurer

Frontiers in Medicine

doi 10.3389/fmed.2025.1658890

1,575 views

Systematic Review

Published on 17 Oct 2025

Neuroimaging evidence for central mechanisms of acupuncture in non-specific low back pain: a systematic review and meta-analysis

in Translational Medicine

Frank Fan Huang
Jiajun Liu
Manqi Lu
Yixun Wu
Shanshan Zhen
Yihui Cai
Zhaoxue Liu
Mingwang Qiu
Wenwu Xiao
Yuxi Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1657241

2,417 views

Original Research

Published on 16 Oct 2025

An experimental study on the pollen particle blocking efficacy of a barrier nasal mask

in Translational Medicine

Yan Zhang
Na Lu
Yuxiang Zhao
Jinping Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1681440

1,065 views

Original Research

Published on 16 Oct 2025

Clinical impact of collagen sponge combined with substance P on maxillofacial trauma repair in rats

in Translational Medicine

Qian Wang
Yong Zhang
Yan Guo
Xiaolan Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1631988

1,005 views

Original Research

Published on 15 Oct 2025

A six-gene expression signature in peripheral blood mononuclear cells effectively diagnoses osteoarthritis

in Translational Medicine

Dong Yu
Wei Ding
Xiuru Xue
Zheng Zhang
Jinchang Meng
Bin Yang
Chunlin Liang
Guanghui Zhao
Xiangmao Bu
Wei Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1632348

1,299 views

651 articles

articles

Identification and validation of novel risk genes for intervertebral disc disorder by integrating large-scale multi-omics analyses and experimental studies

Efficacy of Fu’s Subcutaneous Needling for chronic non-specific neck pain and its effect on muscle elasticity: a randomized controlled trial

A Dual-input deep learning architecture for classification and latency estimation in ABR signals

Diagnostic Prediction Model for Acute Ischemic Stroke Using Stress Hyperglycemia and Neutrophil-to-Lymphocyte Ratios

Influence of different urine preservation methods and addition of preservatives on quantitative detection of 24-h urinary protein

Mechanical stress-mediated immune and inflammatory regulation: a bibliometric and visualization analysis of mechanoimmunology based on two databases

Digit salvage therapy with integrated Chinese and Western medicine: report of case series

Cold Agglutinin Syndrome in a Patient with Metastatic Breast Cancer: A Case Report

Biomechanical comparison of five fixation methods in minimally invasive hallux valgus osteotomy: a three-dimensional finite element analysis

The role of reactive oxygen species-mitophagy regulation in the treatment of osteoarthritis by active Chinese herbal medicine monomers: a review

A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysisAssociation between smoking, periodontal inflammation, and alveolar bone resorption in chronic periodontitis: a meta-analysis

Application of composite layered repair system using titanium mesh, bone cement and vacuum sealing drainage for chest wall defect

Targeted metabolomic profiling reveals inflammation–associated longitudinal changes in plasma metabolites following on-pump coronary bypass surgery

Longitudinal Impact of Radiotherapy on Cardiac Function in Cancer Patients: A Retrospective Cohort Study of Risk Factors and Clinical Outcome

Unraveling the genetic links between obesity or insulin resistance and breast cancer through the impact of CD295 and ITLN1 SNPs with DNA damage in a case-controlled study with bioinformatics analysis

Effect of inflammation on neurovascular coupling, microperfusion, and clinical outcomes in ischemic stroke patients: a case series report

Comprehensive genetic screening of 70 severe adolescent idiopathic scoliosis probands reveals novel pathogenic variants and syndromic associations

Automatic measurement of mesenteric vascular and portal vein parameters via PE-NET in the diagnosis of Crohn’s disease

Sinomenine in cerebral ischemia: mechanisms, delivery strategies, and the emerging multifunctional biomaterials of the bone–brain axis

Imaging of human airways by endoscope-compatible dynamic microscopic optical coherence tomography

Neuroimaging evidence for central mechanisms of acupuncture in non-specific low back pain: a systematic review and meta-analysis

An experimental study on the pollen particle blocking efficacy of a barrier nasal mask

Clinical impact of collagen sponge combined with substance P on maxillofacial trauma repair in rats

A six-gene expression signature in peripheral blood mononuclear cells effectively diagnoses osteoarthritis