Frontiers in Medicine

Original Research

Published on 13 Jan 2026

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

Mohammad Sami El Muhtaseb
Layan Nidal Ismail
Tala A. Haddad
Huthifa Ghanayem
Shrouq Qudah
Daoud O. Al Aruri
Mohammad Abufaraj

Frontiers in Medicine

doi 10.3389/fmed.2025.1630125

662 views

Review

Published on 13 Jan 2026

The novel antidiabetic medications on diabetic retinopathy: relevant molecular mechanisms, advancing diagnostic innovations, and therapeutic implications

Song Wen
Chenglin Xu
Yue Yuan
Lijiao Chen
Yishu Ren
Zhimin Xu
Jianlan Jin
Jiyu Li
Ligang Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1670643

1,504 views

Original Research

Published on 13 Jan 2026

Risk factors associated with knee osteoarthritis severity and their correlation with Kellgren–Lawrence grade

Taiya Chen
Jie Ma
Bi Liu
Shelei Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1744478

582 views

Review

Published on 13 Jan 2026

Artificial intelligence for precision management of epithelial ovarian cancer: a comprehensive review

Qing Liu
Chunhua Zhang
Peiquan Li
Ruiyi Jing
Lei Bi
Weiping Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1713629

765 views

Review

Published on 13 Jan 2026

Advances in the application of artificial intelligence in ophthalmic education and clinical training

Mingsi Chi
Ying Cui
Lei Xi

Frontiers in Medicine

doi 10.3389/fmed.2025.1753411

1,095 views

Original Research

Published on 13 Jan 2026

Efficacy evaluation and predictive value of IL-20 and Apelin-13 after cataract surgery by phacoemulsification combined with IOL implantation

Shuang Liu
Min Yang
Shengwei Wu
Dawei Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1737194

557 views

Review

Published on 13 Jan 2026

Advancements in understanding neuropsychiatric lupus: deciphering immune heterogeneity with single-cell resolution

Zhou Fan
Wang Hai
Zeng Xianyi
Xie Baozhao
Yan Jichun

Frontiers in Medicine

doi 10.3389/fmed.2025.1732805

1,206 views

Original Research

Published on 13 Jan 2026

The relationship between axial length and anterior segment biometry in high axial myopic Chinese students aged 7 to 18 years

Zengrui Zhang
Jingyu Mu
Yanrong Yang
Yun Dai
Junguo Duan

Frontiers in Medicine

doi 10.3389/fmed.2025.1671451

656 views

Original Research

Published on 13 Jan 2026

Differences in the aging of the spine according to physical activity levels in older women

Jessica Brusa
Valerio Giustino
Giuseppe Messina
Ligia Juliana Dominguez
Dorota Kostrzewa-Nowak
Mario Barbagallo
Robert Nowak
Ignazio Leale
Antonino Patti
Antonino Bianco

Frontiers in Medicine

doi 10.3389/fmed.2025.1730935

854 views

Original Research

Published on 13 Jan 2026

CAR-T cell therapy in TP53-mutated CNS lymphoma: overcoming a high-risk genetic barrier

Danyang Li
Rui Liu
Zhonghua Fu
Fan Yang
Lixia Ma
Miaomiao Cao
Yuelu Guo
Biping Deng
Alex H. Chang
Qinlong Zheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1731589

852 views

Review

Published on 13 Jan 2026

Update of the sequential organ failure assessment score: current status and challenges?

Jiafei Yu
Kangwei Sun
Yiping Zhou
Yushi Fan
Xinyun Zhang
Heyu Chen
Lanxin Cao
Kai Zhang
Gensheng Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1733090

1,287 views

Systematic Review

Published on 13 Jan 2026

Inspiratory muscle training in weaning from prolonged mechanical ventilation: a systematic review and meta-analysis

Francisca A. Andrade-Rebolledo
Guillermo Villagra-Morales
Leonardo A. Pérez

Frontiers in Medicine

doi 10.3389/fmed.2025.1719837

2,214 views

Original Research

Published on 13 Jan 2026

A radiomic model leveraging conventional and Hessian matrix-based radiomic features from DCE-MRI for predicting efficacy of neoadjuvant chemotherapy in patients with HER2-low breast cancer

Yuwei Zou
Bingxin Zhao
Yan Mao
Meng Lv
Yongmei Wang
Xiaohui Su
Zaixian Zhang
Jie Wu
Qi Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1639977

496 views

Original Research

Published on 13 Jan 2026

Comparative effectiveness of FAST combined with MRI and CT in wound evaluation of blunt abdominal trauma

Fugang Chen
Yu Wang
Xiaoqiang Liu
Zhaoyun Wang
Xin Li
Xueshuang Tang
Jun Gao

Frontiers in Medicine

doi 10.3389/fmed.2025.1702765

576 views

Original Research

Published on 13 Jan 2026

A novel homozygous splice-site variant in the FOCAD gene causing infantile liver cirrhosis and neutropenia: expanding disease phenotype and successful surgical treatment

Ekaterina Nuzhnaya
Elena Zaklyazminskaya
Viktoriia Zabnenkova
Darya Akimova
Evgeny Tatarsky
Lana Dzik
Andrey Surkov
Natalia Zhurkova
Andrey Filin
Aleksej Metelin

Frontiers in Medicine

doi 10.3389/fmed.2025.1680857

737 views

Review

Published on 13 Jan 2026

Necrotic pancreatitis: modern approaches to the prevention of infected necrosis

Murat K. Jakanov
Gulnur G. Gainollina
Bazylbek S. Zhakiev
Mikhail A. Topchiev
Bulat A. Kurmanbayev

Frontiers in Medicine

doi 10.3389/fmed.2025.1695035

1,802 views

Original Research

Published on 13 Jan 2026

Construction and application of an evidence-based prevention and management protocol for postoperative hypoxemia in elderly patients with hip fractures

Yu Zhang
Xi Chen
Yingqi Zhang
Zhirong Ma
Lili Zhao
Haijiao Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1667172

585 views

Original Research

Published on 13 Jan 2026

The role of epithelial membrane-associated mucin 4 in ocular surface health and corneal wound healing

Sara A. Adelman
Erin A. Hisey
Sangwan Park
Nayone Lantyer-Araujo
Melinda M. Quan
Kathryn Sandberg
Sabina Khan
Meher Khan
Courtney A. Dreyer
Sara M. Thomasy

Frontiers in Medicine

doi 10.3389/fmed.2025.1720986

691 views

Original Research

Published on 13 Jan 2026

Prevalence and prognostic value of baseline and post-treatment renal insufficiency in colorectal cancer patients: a large retrospective cohort study of 10,581 patients in Shanghai, China (2019–2023)

Juan Li
Chen Guang Bai
Baoshuai Liu
Shouyu Pan
Lianjie Liu
Jianjun Jiang
Jian Lu
Guangwen Cao
Wei Zhang
Xian Hua Gao

Frontiers in Medicine

doi 10.3389/fmed.2025.1671990

730 views

Original Research

Published on 13 Jan 2026

The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke

Yuping Huang
Xiaoxiong Huang
Kun He
Weikun Zhang
Yuxi Liu
Luqiang Li
Lu Yuan
Fei Yang
Wen Zeng

Frontiers in Medicine

doi 10.3389/fmed.2025.1720646

751 views

Original Research

Published on 13 Jan 2026

Open- and closed-source LLMs in medical and engineering education

Liping Sun
Ya Li
Hongxing Kan
Jianhua Shu
Huanqing Xu
Chengle Li
Guokun Shi
Ziyang Wang
Xueqi Wang
Li Jin

Frontiers in Medicine

doi 10.3389/fmed.2025.1751813

1,025 views

Original Research

Published on 13 Jan 2026

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

Xuetong Zhang
Wenjun Cui
Min Chen
Min Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1742480

841 views

Original Research

Published on 13 Jan 2026

Lower bioelectrical impedance phase angle is associated with COPD and is a marker for increased risks in elderly COPD patients

JinHua Qian
Min Xu
ZhaoXi Zhang
YuJie Wu
GuoQing Wang
XiaoYun Fan

Frontiers in Medicine

doi 10.3389/fmed.2025.1703621

581 views

Case Report

Published on 13 Jan 2026

Case Report: Nebulized platelet-rich plasma facilitates resolution of post-infective pulmonary consolidation and cavitation in a lung cancer survivor

Zane Sherif
Kirralee Sherif

Frontiers in Medicine

doi 10.3389/fmed.2025.1738044

1,250 views

21,205 Publications

volumes

Volume 12 - 2025

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

The novel antidiabetic medications on diabetic retinopathy: relevant molecular mechanisms, advancing diagnostic innovations, and therapeutic implications

Risk factors associated with knee osteoarthritis severity and their correlation with Kellgren–Lawrence grade

Artificial intelligence for precision management of epithelial ovarian cancer: a comprehensive review

Advances in the application of artificial intelligence in ophthalmic education and clinical training

Efficacy evaluation and predictive value of IL-20 and Apelin-13 after cataract surgery by phacoemulsification combined with IOL implantation

Advancements in understanding neuropsychiatric lupus: deciphering immune heterogeneity with single-cell resolution

The relationship between axial length and anterior segment biometry in high axial myopic Chinese students aged 7 to 18 years

Differences in the aging of the spine according to physical activity levels in older women

CAR-T cell therapy in TP53-mutated CNS lymphoma: overcoming a high-risk genetic barrier

Update of the sequential organ failure assessment score: current status and challenges?

Inspiratory muscle training in weaning from prolonged mechanical ventilation: a systematic review and meta-analysis

A radiomic model leveraging conventional and Hessian matrix-based radiomic features from DCE-MRI for predicting efficacy of neoadjuvant chemotherapy in patients with HER2-low breast cancer

Comparative effectiveness of FAST combined with MRI and CT in wound evaluation of blunt abdominal trauma

A novel homozygous splice-site variant in the FOCAD gene causing infantile liver cirrhosis and neutropenia: expanding disease phenotype and successful surgical treatment

Necrotic pancreatitis: modern approaches to the prevention of infected necrosis

Construction and application of an evidence-based prevention and management protocol for postoperative hypoxemia in elderly patients with hip fractures

The role of epithelial membrane-associated mucin 4 in ocular surface health and corneal wound healing

Prevalence and prognostic value of baseline and post-treatment renal insufficiency in colorectal cancer patients: a large retrospective cohort study of 10,581 patients in Shanghai, China (2019–2023)

The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke

Open- and closed-source LLMs in medical and engineering education

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

Lower bioelectrical impedance phase angle is associated with COPD and is a marker for increased risks in elderly COPD patients

Case Report: Nebulized platelet-rich plasma facilitates resolution of post-infective pulmonary consolidation and cavitation in a lung cancer survivor

volumes

Volume 12 - 2025

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in patients with colorectal cancer: a retrospective study

The novel antidiabetic medications on diabetic retinopathy: relevant molecular mechanisms, advancing diagnostic innovations, and therapeutic implications

Risk factors associated with knee osteoarthritis severity and their correlation with Kellgren–Lawrence grade

Artificial intelligence for precision management of epithelial ovarian cancer: a comprehensive review

Advances in the application of artificial intelligence in ophthalmic education and clinical training

Efficacy evaluation and predictive value of IL-20 and Apelin-13 after cataract surgery by phacoemulsification combined with IOL implantation

Advancements in understanding neuropsychiatric lupus: deciphering immune heterogeneity with single-cell resolution

The relationship between axial length and anterior segment biometry in high axial myopic Chinese students aged 7 to 18 years

Differences in the aging of the spine according to physical activity levels in older women

CAR-T cell therapy in TP53-mutated CNS lymphoma: overcoming a high-risk genetic barrier

Update of the sequential organ failure assessment score: current status and challenges?

Inspiratory muscle training in weaning from prolonged mechanical ventilation: a systematic review and meta-analysis

A radiomic model leveraging conventional and Hessian matrix-based radiomic features from DCE-MRI for predicting efficacy of neoadjuvant chemotherapy in patients with HER2-low breast cancer

Comparative effectiveness of FAST combined with MRI and CT in wound evaluation of blunt abdominal trauma

A novel homozygous splice-site variant in the FOCAD gene causing infantile liver cirrhosis and neutropenia: expanding disease phenotype and successful surgical treatment

Necrotic pancreatitis: modern approaches to the prevention of infected necrosis

Construction and application of an evidence-based prevention and management protocol for postoperative hypoxemia in elderly patients with hip fractures

The role of epithelial membrane-associated mucin 4 in ocular surface health and corneal wound healing

Prevalence and prognostic value of baseline and post-treatment renal insufficiency in colorectal cancer patients: a large retrospective cohort study of 10,581 patients in Shanghai, China (2019–2023)

The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke

Open- and closed-source LLMs in medical and engineering education

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

Lower bioelectrical impedance phase angle is associated with COPD and is a marker for increased risks in elderly COPD patients

Case Report: Nebulized platelet-rich plasma facilitates resolution of post-infective pulmonary consolidation and cavitation in a lung cancer survivor

The relationship between axial length and anterior segment biometry in high axial myopic Chinese students aged 7 to 18 years