Frontiers in Microbiology | Microbial Physiology and Metabolism

Original Research

Published on 12 Nov 2025

Lactobacillus reuteri-derived HDCA suppresses PEDV replication while alleviating virus-triggered inflammation in piglets

in Microbial Physiology and Metabolism

Zhibiao Bian
Qianqian Li
Hongchao Gou
Yan Li
Zhiyong Jiang
Pinpin Chu
Shaolun Zhai
Huahua Kang
Chunling Li
Guanghui Zhao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1669658

1,600 views

Original Research

Accepted on 11 Nov 2025

Magnesium modulates the stress response of oral streptococci to environmental and antibiotic challenges by altering cell envelope and nutrient transport pathways

in Microbial Physiology and Metabolism

Surabhi Mishra

Frontiers in Microbiology

304 views

Original Research

Published on 07 Nov 2025

Requirement of ClpX for CtsR dissociation from its operator elements upon heat stress in Bacillus subtilis

in Microbial Physiology and Metabolism

Marco Harms
Chelsea Kaden
Larissa M. Busch
Vishnu M. Dhople
Ulf Gerth
Manuela Gesell Salazar
Stephan Michalik
Zhanetta Zhatarova
Uwe Völker
Alexander Reder

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699655

1,677 views

Original Research

Published on 07 Nov 2025

Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in Inonotus glomeratus

in Microbial Physiology and Metabolism

Chengbo Peng
Meng Meng
Xiaolong Yuan
Jiaojun Yu
Boyi Wang
Li Zhong
Yi Wang
Lu Li
Tingwen He
Yuan Zheng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1658730

1,801 views

Original Research

Published on 31 Oct 2025

Screening of microbial consortium with high efficiency of lignin-degrading and its synergistic metabolic mechanism

in Microbial Physiology and Metabolism

Jinchuang Ru
Zhiyang Jiang
Jiayu Li
Xiang Li
Zhencheng Su
Tong Li
Mingkai Xu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1709019

2,081 views

Original Research

Published on 31 Oct 2025

A two-component system MechNtrB/MechNtrC related to nitrogen metabolism regulation in Micromonospora echinospora DSM43816

in Microbial Physiology and Metabolism

Yuxin Long
Jiayi Lu
Siyi Leng
Congsi Li
Haiyan Ni
Long Zou
Zhiming Wu
Zhong-er Long

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1678324

1,148 views

Original Research

Published on 31 Oct 2025

A two-stage strategy for methanogenesis suppression and rapid acetogenic biofilm formation in microbial electrosynthesis

in Microbial Physiology and Metabolism

Jacopo Ferretti
Marika A. J. Zegers
Marco Zeppilli
Ludovic Jourdin

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1655259

1,681 views

Original Research

Published on 31 Oct 2025

Type IV minor pilin ComN predicted the USS-receptor in Pasteurellaceae

in Microbial Physiology and Metabolism

Stian Aleksander Helsem
Kristian Alfsnes
Stephan A. Frye
Alexander Hesselberg Løvestad
Ole Herman Ambur

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1647523

1,814 views

Original Research

Published on 30 Oct 2025

Pig-L mediates virulence, biofilm formation, and oxidative stress tolerance in Clostridioides difficile

in Microbial Physiology and Metabolism

Yumei Cheng
Huilin Hu
Tingyu Huang
Xiang Luo
Fahui Chen
Peng Shi
Weihao Ma
Yingjun Lu
Siyu Lan
Guzhen Cui

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1691769

1,303 views

Review

Published on 27 Oct 2025

Stereospecific lactylation in bacteriology: L/D-lactate partitioning shapes host metabolic-disease axis

in Microbial Physiology and Metabolism

Sirui Wang
Leiliang Zhang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1693700

1,664 views

Original Research

Published on 23 Oct 2025

Acetylation of the histone-like protein HBsu at specific sites alters gene expression during sporulation in Bacillus subtilis

in Microbial Physiology and Metabolism

Liya Popova
Hritisha Pandey
Olivia R. Schreiber
Charalampos Papachristou
Valerie J. Carabetta

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1629989

1,477 views

Original Research

Published on 22 Oct 2025

Prevalence, sequence diversity, and amplification of an IS-associated enterotoxin gene, astA, in Escherichia coli

in Microbial Physiology and Metabolism

Tadasuke Ooka
Sakura Arai
Kenichi Lee
Yasuhiro Gotoh
Akiko Kubomura
Naoko Imuta
Yukiko Hara-Kudo
Sunao Iyoda
Tetsuya Hayashi
Junichiro Nishi

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1635769

1,621 views

Original Research

Published on 20 Oct 2025

Integrated morphological, proteomic and metabolomic analyses reveal response mechanisms of microalgae under uranium exposure

in Microbial Physiology and Metabolism

Mengwei Han
Xu Yang
Bin Dong
Jinlong Lai
Hailing Xi
Sanping Zhao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1679056

1,649 views

Original Research

Published on 17 Oct 2025

Mfd deficiency decreases the abundance of complete transcripts of sporulation genes and alters sporogenesis and the structure of dormant Bacillus subtilis spores

in Microbial Physiology and Metabolism

Holly Anne Martin
Robert Heron
Hilda Leyva-Sanchez
Ryan King Perez
Amber Callaway
Tatiana Ermi
Aude Picard
Jessica Grifaldo
Jesse L. Barnes
Mario Pedraza-Reyes

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1680580

2,168 views

Original Research

Published on 15 Oct 2025

Proteomic analyses of the regulatory mechanisms underlying Pochonia chlamydosporia infection in Parascaris equorum eggs

in Microbial Physiology and Metabolism

Yuan Ma
Jinbao Lv
Luyao Hao
Zhengyi Li
Chengyu Ma
Rui Wang
Lili Jiang
Zhaobin Fan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1644912

2,462 views

Review

Published on 13 Oct 2025

From mechanisms to precision medicine: the role of organoids in studying the gut microbiota-tumor microenvironment axis

in Microbial Physiology and Metabolism

Si-yang Zheng
You-yu Su
Fu-liang Cai
Da-fang Xu
Yong-qiang Xu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1669482

2,606 views
1 citation

Original Research

Published on 10 Oct 2025

Whole genome sequence of Penicillium kloeckeri and insight into its growth-promoting, saline alkaline tolerance properties

in Microbial Physiology and Metabolism

Wenxiao Cui
Yafen Wu
Bin Ni
Jia Cao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1675497

2,887 views

Original Research

Published on 29 Sep 2025

Transcriptomic and metabolomic analysis of a non-cyp51A mutant azole-resistant Aspergillus fumigatus isolated from Ningxia, China

in Microbial Physiology and Metabolism

Wanting Ma
Yuting Kang
Qiujie Li
Pengtao Wang
Wei Jia

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1666905

3,426 views

Original Research

Published on 26 Sep 2025

Bacillus amyloliquefaciens G02 enhances selenium uptake in lettuce (Lactuca sativa) by improving soil selenium availability and rhizosphere microbiome regulation

in Microbial Physiology and Metabolism

Bingzhi Huang
Bei Li
Guofei Pan
Danni Huang
Guoming Yang
Yanmin Ma
Fengshuo Ya
Mingliang Rao
Yanyan Wei

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1656037

2,915 views

Original Research

Published on 24 Sep 2025

Fermentation-driven microbial and metabolic shifts in filler tobacco leaves of different grades

in Microbial Physiology and Metabolism

Chen He
Shaoxin Yang
Shengnan Dong
Shengxiao Wang
Pengfei Zhang
Yang Yang
Delong Xu
Rongchao Yang
Bo Zeng
Yanqi Hu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1651289

3,100 views
1 citation

Original Research

Published on 24 Sep 2025

GerAB residues predicted to interfere with water passage based on steered molecular dynamics are key to germinosome functionality

in Microbial Physiology and Metabolism

Longjiao Chen
Houdijn Beekhuis
Christina van den Bosch
Gianni Vinay
George Korza
Jocelyne Vreede
Peter Setlow
Stanley Brul

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1656964

3,353 views

Original Research

Published on 19 Sep 2025

Anaerobic gut fungi as biocatalysts: metabolic and physiological analysis of anaerobic gut fungi under diverse cultivation conditions

in Microbial Physiology and Metabolism

Kevin Edward Schulz
Dominik Scholz
Anto Rafael Sikirić
Daniela Rambow
Anke Neumann
Katrin Ochsenreither

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1662047

3,542 views

Original Research

Published on 16 Sep 2025

Coordinated regulation of propionyl-CoA carboxylase subunits drives precursor flux optimization in spinosad production

in Microbial Physiology and Metabolism

Ziyuan Xia
Xiaomin Li
Xirong Liu
Li Cao
Duo Jin
Zirui Dai
Baolong Bai
Qian Liu
Jie Rang
Zirong Zhu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1643527

2,733 views

Original Research

Published on 16 Sep 2025

The effect of cCMP and cUMP on growth of Pseudomonas aeruginosa

in Microbial Physiology and Metabolism

Christoph Risser
Justin Rothschuh
Heike Bähre
Detlef Neumann
Roland Seifert
Bastian Schirmer

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1675794

3,219 views

2,809 articles

articles

Lactobacillus reuteri-derived HDCA suppresses PEDV replication while alleviating virus-triggered inflammation in piglets

Magnesium modulates the stress response of oral streptococci to environmental and antibiotic challenges by altering cell envelope and nutrient transport pathways

Requirement of ClpX for CtsR dissociation from its operator elements upon heat stress in Bacillus subtilis

Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in Inonotus glomeratus

Screening of microbial consortium with high efficiency of lignin-degrading and its synergistic metabolic mechanism

A two-component system MechNtrB/MechNtrC related to nitrogen metabolism regulation in Micromonospora echinospora DSM43816

A two-stage strategy for methanogenesis suppression and rapid acetogenic biofilm formation in microbial electrosynthesis

Type IV minor pilin ComN predicted the USS-receptor in Pasteurellaceae

Pig-L mediates virulence, biofilm formation, and oxidative stress tolerance in Clostridioides difficile

Stereospecific lactylation in bacteriology: L/D-lactate partitioning shapes host metabolic-disease axis

Acetylation of the histone-like protein HBsu at specific sites alters gene expression during sporulation in Bacillus subtilis

Prevalence, sequence diversity, and amplification of an IS-associated enterotoxin gene, astA, in Escherichia coli

Integrated morphological, proteomic and metabolomic analyses reveal response mechanisms of microalgae under uranium exposure

Mfd deficiency decreases the abundance of complete transcripts of sporulation genes and alters sporogenesis and the structure of dormant Bacillus subtilis spores

Proteomic analyses of the regulatory mechanisms underlying Pochonia chlamydosporia infection in Parascaris equorum eggs

From mechanisms to precision medicine: the role of organoids in studying the gut microbiota-tumor microenvironment axis

Whole genome sequence of Penicillium kloeckeri and insight into its growth-promoting, saline alkaline tolerance properties

Transcriptomic and metabolomic analysis of a non-cyp51A mutant azole-resistant Aspergillus fumigatus isolated from Ningxia, China

Bacillus amyloliquefaciens G02 enhances selenium uptake in lettuce (Lactuca sativa) by improving soil selenium availability and rhizosphere microbiome regulation

Fermentation-driven microbial and metabolic shifts in filler tobacco leaves of different grades

GerAB residues predicted to interfere with water passage based on steered molecular dynamics are key to germinosome functionality

Anaerobic gut fungi as biocatalysts: metabolic and physiological analysis of anaerobic gut fungi under diverse cultivation conditions

Coordinated regulation of propionyl-CoA carboxylase subunits drives precursor flux optimization in spinosad production

The effect of cCMP and cUMP on growth of Pseudomonas aeruginosa