Frontiers in Microbiology | Microorganisms in Vertebrate Digestive Systems

Review

Published on 20 Nov 2025

Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies

in Microorganisms in Vertebrate Digestive Systems

Bingbing Bai
Jianing Ma
Wenlong Xu
Xiaomin Chen
Xu Chen
Chao Lv
Wei Su
Yaoxu Li
Hongyin Sun
Baoyin Zhang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699893

3,412 views

Original Research

Published on 20 Nov 2025

Exploring the characteristics of gut microbiota in the development and progression of early-stage colorectal cancer based on metagenomic sequencing

in Microorganisms in Vertebrate Digestive Systems

Qianqian Chen
Jing Guan
Lu Yang
Jie Lv
Gen Gui
Jianhua Xu
Zhaoyun Yang
Xu Wang
Bin Sun

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1658160

1,757 views

Original Research

Published on 18 Nov 2025

Chewable tablets containing rape bee pollen and maca attenuate testosterone propionate–induced benign prostatic hyperplasia in Sprague–Dawley rats by regulating the gut microbiota and modulating the IL-6/JAK2/STAT3 signaling pathway

in Microorganisms in Vertebrate Digestive Systems

Xiaoqiang Huang
Guohua Ru
Hengyun Tian
Pengbo Zhang
Hongchang Zhao
Shouren Zhang
Sijie Wang
An Jia
Wanli Zhao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1547724

2,301 views

Original Research

Published on 18 Nov 2025

Gut microbiota-based biomarkers for precision subtype classification and mechanistic understanding of biliary and hyperlipidemic acute pancreatitis

in Microorganisms in Vertebrate Digestive Systems

Xinyu Deng
Xueqian Wu
Ruobing Wang
Xiaohan Qiao
Ting Cao
Yao Xu
Qun Jin
Lingling Jia
Wei Liang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1695811

1,725 views

Original Research

Published on 14 Nov 2025

Alpha-linolenic acid reshapes the gastrointestinal ecology to enhance immune function in dairy cows: insights from microbiome and metabolome profiling

in Microorganisms in Vertebrate Digestive Systems

Hongjin Ji
Zhantao Yang
Yangyi Hao
Yajing Wang
Zhijun Cao
Hongjian Yang
Wei Wang
Shengli Li

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1687786

1,819 views

Review

Published on 13 Nov 2025

Deciphering the urinary microbiome and urological cancers: from correlation to mechanisms and treatment

in Microorganisms in Vertebrate Digestive Systems

Zunwen Zheng
Deqian Xie
Yongzheng Han
Guandu Li
Shijin Wang
Xiaoman Zhang
Tao Huang
Wenfei Xu
Guangzhen Wu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699308

2,305 views
1 citation

Original Research

Published on 13 Nov 2025

Characterizing probiotic profiles using genomic and metabolomic insights into chicken cecum-derived Bacillus subtilis YB-114246

in Microorganisms in Vertebrate Digestive Systems

Jiajun Yang
Ying Li
Jing Wang
Bo Zhang
Hao Zhang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1706551

1,365 views

Original Research

Published on 13 Nov 2025

Diet-microbiome coevolution: the core mechanism for semi-aquatic adaptation and cross-habitat niche coexistence of the web-footed shrew (Nectogale elegans)

in Microorganisms in Vertebrate Digestive Systems

Jiayi Jiang
Sibei Zhou
Jia Song
Chongxie Xia
Xuexiang Yang
Kun Yang
Fengjun Li

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1711143

1,826 views
1 citation

Original Research

Published on 13 Nov 2025

Integrated analysis of fecal microbiota and metabolomics reveals unique characteristics of asymptomatic and classic celiac disease

in Microorganisms in Vertebrate Digestive Systems

Shanxia Yao
Shenglong Xue
Na Li
Tian Shi
Yan Feng
Munila Maimaiti
Ayinuer Maimaitireyimu
Halina Halike
Feng Gao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1636007

1,740 views

Original Research

Published on 12 Nov 2025

Integrated gut microbiome and metabolomics analysis reveals microbial-metabolic cross-talk in allergic rhinitis

in Microorganisms in Vertebrate Digestive Systems

Guangchen Sun
Shouyan Zhao
Hehua Huang
Wenchao Guan
Xinzhuo Wang
Hong Zhang
Min Zhang
Denghan Hou
Chong Xu
Ruonan Chai

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1652915

3,425 views

Original Research

Published on 12 Nov 2025

Age-related gut microbiota succession in Neijiang pigs: insights for precision feeding and productivity

in Microorganisms in Vertebrate Digestive Systems

Qihang Wu
Shijie Hu
Yan Wang
Yuanyuan Wu
Ye Zhao
Lili Niu
Xiaofeng Zhou
Linyuan Shen
Yihui Liu
Ying Chen

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1698169

1,679 views

Original Research

Published on 12 Nov 2025

Sishen Pill treats spleen-kidney yang deficiency IBS-D by influencing ATPase activity and intestinal microbiota

in Microorganisms in Vertebrate Digestive Systems

Qi Long
Liwen Li
Zhoujin Tan
Na Deng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1610928

1,499 views

Systematic Review

Published on 12 Nov 2025

Short-chain fatty acids and type 2 diabetes: a bibliometric analysis of knowledge structure, research hotspots, and future directions

in Microorganisms in Vertebrate Digestive Systems

Likun Zheng
Rongsheng Jiang
Jinxu Fang
Yi Tan
Yan Wang
Lian Li
Mingjun Liu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1697421

2,858 views

Original Research

Published on 12 Nov 2025

Clinical features and gut microbiota alterations in hypertensive individuals with left ventricular hypertrophy

in Microorganisms in Vertebrate Digestive Systems

Liang Cai
Guo-Qiang Liu
Chun-Mei Zeng
Wen-Feng Xu
Ri-Na Jiang
Hai-Yan Chen

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1647668

1,327 views

Original Research

Published on 12 Nov 2025

Regulatory effects of berberine on intestinal microecology in mice with ulcerative colitis

in Microorganisms in Vertebrate Digestive Systems

Xinyi Xu
Bin Zhao
Pingyu Liu
Xiaohui Tang
Zonglang Lai
Na Song
Jun Cheng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1649947

2,432 views

Review

Published on 11 Nov 2025

Washed microbiota transplantation: candidates for a novel strategy for ameliorating autism spectrum disorder

in Microorganisms in Vertebrate Digestive Systems

Shuo Feng
Jiangyan Wang
Xinyu Si
Shenghua Lu
Caimei Lu
Zheng Gao
Juan Yang
Jiali Wu
Xingxiang He
Lei Wu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1688325

2,529 views

Original Research

Published on 10 Nov 2025

Sustained hyperuricemia disrupts enterohepatic circulation through 12α-hydroxy BA and gut microbiota

in Microorganisms in Vertebrate Digestive Systems

Tong Zou
Ruixiao Zhang
Zeqing Chen
Haiping Duan
Zhaoguo Wang
Ruipeng Gao
Xin Chen
Hongqiang Wang
Yue Zhao
Xiaofeng Wang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1671409

1,629 views

Original Research

Published on 10 Nov 2025

Effects of the monolaurin based feed additive MGOsyn on methane production, rumen fermentation, and microbial communities using rumen fluid from Hanwoo steers in an in vitro study

in Microorganisms in Vertebrate Digestive Systems

Mi Ae Park
Seoyun Son
Da Jung Lim
Hee Seop Yu
Yong Hee Yoon
Seon-Ho Kim
Sang-Suk Lee
Dae-Hyuk Kim
Yangseon Kim

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699688

1,986 views

Original Research

Published on 10 Nov 2025

Acetate-based syntrophy enhances methane production potential of ruminant feces

in Microorganisms in Vertebrate Digestive Systems

Jian Liu
Yujie Sha
Run Dang
Lifeng Zhou
Meng Zhou
Yang Tan
Jinming Wang
Ge Ran
Wei Xie
Dong Xia

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1706620

1,570 views

Original Research

Published on 07 Nov 2025

Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota

in Microorganisms in Vertebrate Digestive Systems

Jiangsong Cao
Ziyu Zhang
Xiongwei Liu
Ying Zhou
Jiaxin Li
Xinyue Wang
Chang Liu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1701829

2,045 views

Original Research

Published on 06 Nov 2025

BCAA supplementation enhances milk fat synthesis in Yili mares and promotes foal growth through remodeling of intestinal amino acid metabolism

in Microorganisms in Vertebrate Digestive Systems

Chen Meng
Yaqi Zeng
Jianwen Wang
Xinkui Yao
Jun Meng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699614

1,955 views

Original Research

Published on 06 Nov 2025

Evaluating the rumen microbial community of genetically divergent spring-calving dairy cows grazing grass-only or grass-clover swards at different stages of the grazing season

in Microorganisms in Vertebrate Digestive Systems

Charles Dwan
Anubhav Das
Paul W. O’Toole
Tom F. O’Callaghan
Dara Meehan
Deirdre Hennessy
Hannah Irish
Frank Buckley
Ben Lahart

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1642486

1,838 views

Original Research

Published on 06 Nov 2025

Multi-omics analysis reveals gut microbial and metabolic signatures in metabolic dysfunction-associated steatotic liver disease

in Microorganisms in Vertebrate Digestive Systems

Muyesaier Maimaitiyiming
Sulitanguli Maihemuti
Tangnuer Aierken
Gulizhati Abulimiti
Tuersinayi Aibaidula
Yaru Guan
Abudoukeyoumu Simayi
Maiwulan Aimaiti
Xingfu Wang
Abula Abuduaini

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1666110

2,307 views

Mini Review

Published on 06 Nov 2025

Gut microbiota on cardiovascular diseases-a mini review on current evidence

in Microorganisms in Vertebrate Digestive Systems

Shouhong Zhang
Jing Li
Liping Li
Xingxing Yuan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1690411

3,261 views
2 citations

1,621 articles

articles

Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies

Exploring the characteristics of gut microbiota in the development and progression of early-stage colorectal cancer based on metagenomic sequencing

Chewable tablets containing rape bee pollen and maca attenuate testosterone propionate–induced benign prostatic hyperplasia in Sprague–Dawley rats by regulating the gut microbiota and modulating the IL-6/JAK2/STAT3 signaling pathway

Gut microbiota-based biomarkers for precision subtype classification and mechanistic understanding of biliary and hyperlipidemic acute pancreatitis

Alpha-linolenic acid reshapes the gastrointestinal ecology to enhance immune function in dairy cows: insights from microbiome and metabolome profiling

Deciphering the urinary microbiome and urological cancers: from correlation to mechanisms and treatment

Characterizing probiotic profiles using genomic and metabolomic insights into chicken cecum-derived Bacillus subtilis YB-114246

Diet-microbiome coevolution: the core mechanism for semi-aquatic adaptation and cross-habitat niche coexistence of the web-footed shrew (Nectogale elegans)

Integrated analysis of fecal microbiota and metabolomics reveals unique characteristics of asymptomatic and classic celiac disease

Integrated gut microbiome and metabolomics analysis reveals microbial-metabolic cross-talk in allergic rhinitis

Age-related gut microbiota succession in Neijiang pigs: insights for precision feeding and productivity

Sishen Pill treats spleen-kidney yang deficiency IBS-D by influencing ATPase activity and intestinal microbiota

Short-chain fatty acids and type 2 diabetes: a bibliometric analysis of knowledge structure, research hotspots, and future directions

Clinical features and gut microbiota alterations in hypertensive individuals with left ventricular hypertrophy

Regulatory effects of berberine on intestinal microecology in mice with ulcerative colitis

Washed microbiota transplantation: candidates for a novel strategy for ameliorating autism spectrum disorder

Sustained hyperuricemia disrupts enterohepatic circulation through 12α-hydroxy BA and gut microbiota

Effects of the monolaurin based feed additive MGOsyn on methane production, rumen fermentation, and microbial communities using rumen fluid from Hanwoo steers in an in vitro study

Acetate-based syntrophy enhances methane production potential of ruminant feces

Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota

BCAA supplementation enhances milk fat synthesis in Yili mares and promotes foal growth through remodeling of intestinal amino acid metabolism

Evaluating the rumen microbial community of genetically divergent spring-calving dairy cows grazing grass-only or grass-clover swards at different stages of the grazing season

Multi-omics analysis reveals gut microbial and metabolic signatures in metabolic dysfunction-associated steatotic liver disease

Gut microbiota on cardiovascular diseases-a mini review on current evidence