Frontiers in Microbiology | Systems Microbiology

Systematic Review

Published on 01 Oct 2025

Beyond just correlation: causal machine learning for the microbiome, from prediction to health policy with econometric tools

in Systems Microbiology

Issam Khelfaoui
Wenxin Wang
Hicham Meskher
Akram Ismael Shehata
Mohammed F. El Basuini
Mohamed F. Abouelenein
Houssem Eddine Degha
Mayada Alhoshy
Islam I. Teiba
Seedahmed S. Mahmoud

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1691503

320 views

Review

Published on 30 Sep 2025

Potential and application of Fusobacterium nucleatum in the diagnosis and treatment of colorectal cancer

in Systems Microbiology

Xin He
Qing Zhao
Jianhong Zhang
Jing Shi
Ningyi Wan
Bin Tang
Bo Tian
Pu Li

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1652702

1,200 views

Original Research

Published on 30 Sep 2025

Parkin overexpression modulates gut-microbiota composition during aging in Drosophila melanogaster

in Systems Microbiology

Larisa Sarghie
Paula Istvan
Ricardo Aparicio
David W. Walker
Robi Tacutu
Marius Surleac

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1672083

924 views

Original Research

Accepted on 29 Sep 2025

Spatiotemporal Dynamics of Bacillus anthracis Under Climate Change: A Machine Learning Approach

in Systems Microbiology

Sameh M.H. Khalaf
Monerah S M Alqahtani
Yousef A Selim
Kenoz O Elsayed
Hager A Bendary

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1659876

354 views

Original Research

Published on 26 Sep 2025

Exploring the gut microbiota-Parkinson’s disease link: preliminary insights from metagenomics and Mendelian randomization

in Systems Microbiology

Jiaji Liu
Le Wang
Ling Su
Jiayi Chen
Ruijun Su

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1654418

2,182 views

Original Research

Published on 24 Sep 2025

Multi-cohort metagenomics reveals strain functional heterogeneity and demonstrates fecal microbial load correction improves colorectal cancer diagnostic models

in Systems Microbiology

Qiucheng Li
Fang Liu
Jianfeng Zhong
Xiaoling Fang
Xinyi Zhang
Huizhen Xiong
Guangyi Li
Honglei Chen

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1656016

2,331 views

Original Research

Published on 19 Sep 2025

Taxonomic and functional profiling of the vulvar microbiome indicates variations related to ecological signatures, aging, and health status

in Systems Microbiology

Arnout Mieremet
Michelle van der Wurff
Lisa Pagan
Edgar Ferrer-González
Jin Seo
Frank H. J. Schuren

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1633147

3,015 views

Original Research

Published on 19 Sep 2025

Enhancing pathogen identification through AI-assisted metagenomic sequencing

in Systems Microbiology

Xiayu Peng
Yong Wei
Xue Zhou

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1634194

2,170 views

Original Research

Accepted on 18 Sep 2025

Exploring the fungal community structure and assembly in different tissues of Gymnadenia conopsea

in Systems Microbiology

Xiu Yin
Yazhou Lu
Hong Quan
Erhao Zhang
Zhongbin Wang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1640133

179 views

Original Research

Accepted on 18 Sep 2025

Microbial-driven valorization of tannery sludge for fatty acids production: unraveling microbiome activity and functional redundancy

in Systems Microbiology

Barbara Tonanzi
Alessio Massimi
Francesco Valentino
Giulia Adele Tuci
Marco Gottardo
Simona Rossetti
Simona Crognale

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1675618

1,134 views

Original Research

Published on 18 Sep 2025

Preliminary exploration of the ability of HUC-MSCs to restore the lung microbiota and related metabolite disorders in IPF treatment: combining 16S sequencing and metabolite analysis

in Systems Microbiology

Shuang Zhou
Yukai Luo
Jun Liu
Jishui Huang
Xiaojing Zhang
Qing-chun Jia
Yijian Lin
Zhenyong Huang
Yiming Zeng
Wenzhao Cheng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1645577

879 views

Original Research

Published on 17 Sep 2025

Structure-guided integrative soft deep clustering analysis of scRNA-seq and scATAC-seq data

in Systems Microbiology

Jiang Xingzuo
Wang Chenyuan
Yao Jiaxi
Wang Chengyuan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1678891

1,549 views

Systematic Review

Published on 16 Sep 2025

Bibliometric analysis of the application of artificial intelligence techniques in bacteriology: a PRISMA-guided research agenda

in Systems Microbiology

Diana Carolina Velasco Cardona
Sebastián Cardona-Acevedo
Alejandro Valencia-Arias
Orlando Pérez-Delgado
Melissa Pinella Vega

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1641967

2,456 views

Original Research

Published on 16 Sep 2025

Computational microbiome pharmacology analysis elucidates the anti-cancer potential of vaginal microbes and metabolites

in Systems Microbiology

Damilola C. Lawore
Smrutiti Jena
Alicia R. Berard
Kenzie Birse
Alana Lamont
Romel D. Mackelprang
Laura Noel-Romas
Michelle Perner
Xuanlin Hou
Elizabeth Irungu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1602217

1,786 views

Review

Published on 16 Sep 2025

The human microbiome in clinical translation: from bench to bedside

in Systems Microbiology

Jhommara Bautista
Carolina E. Echeverría
Iván Maldonado-Noboa
Sofía Ojeda-Mosquera
Camila Hidalgo-Tinoco
Andrés López-Cortés

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1632435

2,553 views

Original Research

Accepted on 15 Sep 2025

Stage-Specific Fecal and Salivary Microbiota Signatures for Non-Invasive Detection of Colorectal Cancer

in Systems Microbiology

Zhenzhen Wu
Zhenzheng Zhu
Chenxi Zhou
Zhenyi Lin
Hujia Yang
Guanjun Jiang
Shuning Ding
Jieru Yu
Leitao Sun

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1658693

216 views