Frontiers in Molecular Biosciences

Original Research

Published on 09 Apr 2025

Identification of metabolomics-based biomarker discovery in individuals with down syndrome utilizing kernel-tree model-enhanced explainable artificial intelligence methodology

in Molecular Diagnostics and Therapeutics

Cemil Colak
Fatma Hilal Yagin
Burak Yagin
Abedalrhman Alkhateeb
Mahmood Basil A. Al-Rawi
Moulay A. Akhloufi
Mohammadreza Aghaei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567199

1,332 views

Original Research

Published on 09 Apr 2025

Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome

in Metabolomics

Jiaqi Liu
Aiwei Wang
Feng Qi
Xiaoyan Liu
Zhengguang Guo
Haidan Sun
Mindi Zhao
Tingmiao Li
Fei Xue
Hai Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547476

1,250 views

Review

Published on 08 Apr 2025

Use of AI-methods over MD simulations in the sampling of conformational ensembles in IDPs

in Biological Modeling and Simulation

Souradeep Sil
Ishita Datta
Sankar Basu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542267

2,848 views

Editorial

Published on 08 Apr 2025

Editorial: Metabolomics in personalized cancer medicine

in Metabolomics

Joana Pinto
Jacopo Troisi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593877

927 views

Original Research

Published on 08 Apr 2025

Differential expression and correlation analysis of global transcriptome for obstructive sleep apnea hypopnea syndrome

in RNA Networks and Biology

Ziyi Chen
Guihua Wang
Lichen Song
Yuanyuan Zhang
Guangming Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1529386

1,684 views

Editorial

Published on 08 Apr 2025

Editorial: Therapeutic mechanism of osteosarcoma

in Molecular Diagnostics and Therapeutics

Siyi Chen
Yang Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597144

1,077 views

Original Research

Published on 07 Apr 2025

Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy

in Metabolomics

Ilona Dudka
João Figueira
Pernilla Wikström
Anders Bergh
Gerhard Gröbner

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1426949

1,369 views

Review

Published on 07 Apr 2025

FOXOs and their roles in acute and chronic neurological disorders

in Molecular Diagnostics and Therapeutics

Yasin Asadi
Rozenn K. Moundounga
Anand Chakroborty
Augustina Pokokiri
Hongmin Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538472

2,389 views

Original Research

Published on 07 Apr 2025

Influence of expression and purification protocols on Gα biochemical activity: kinetics of plant and mammalian G protein cycles

in Protein Biochemistry for Basic and Applied Sciences

Timothy E. Gookin
David Chakravorty
Sarah M. Assmann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1513660

932 views

Original Research

Published on 07 Apr 2025

UPLC-Q-TOF-MS-based unbiased serum metabolomics investigation of cholangiocarcinoma

in Molecular Diagnostics and Therapeutics

Xiaowei Wang
Xuefeng Xu
Ran Jia
Yuanhong Xu
Ping Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549223

1,256 views

Original Research

Published on 04 Apr 2025

Integrated multi-omics analysis reveals the functional and prognostic significance of lactylation-related gene PRDX1 in breast cancer

in Molecular Diagnostics and Therapeutics

Qinqing Wu
Heng Cao
Jiangdong Jin
Dongxu Ma
Yixiao Niu
Yanping Yu
Xiang Wang
Yiqin Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580622

4,125 views

Original Research

Published on 03 Apr 2025

Live cell optical super-resolution microscopy of dystroglycan mutants as a model for dystroglycanopathies in multiple cell lines

in Protein Biochemistry for Basic and Applied Sciences

Francesca Sciandra
Manuela Bozzi
Alina Witt
Paul Goffing
Sonia Covaceuszach
Sandra Blaess
Alberto Cassetta
Maria Giulia Bigotti
Thomas Huser
Andrea Brancaccio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558170

1,186 views

Editorial

Published on 03 Apr 2025

Editorial: Crosstalk between metabolism and immunity

in Molecular Diagnostics and Therapeutics

Jie Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599219

717 views

Brief Research Report

Published on 03 Apr 2025

Determination of sample stability for a broad panel of coagulation parameters and factor assays on the Cobas t 711 analyzer starting from fresh-never-frozen plasma

in Molecular Diagnostics and Therapeutics

Michael Hoffmann
Norbert Gottschalk
Philipp Huber
Vanessa Scheling
Nicole von Allmen
J. Kolja Hegel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1491239

922 views

Original Research

Published on 03 Apr 2025

Paritaprevir as a pan-antiviral against different flaviviruses

in Molecular Biophysics

R. P. Yadav
N. R. Jena

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524951

1,758 views

Original Research

Published on 02 Apr 2025

LT-YOLO: long-term temporal enhanced YOLO for stenosis detection on invasive coronary angiography

in Molecular Diagnostics and Therapeutics

Jiaxin Li
Xiang Tang
Xuesong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558495

1,020 views