Frontiers in Molecular Biosciences

Original Research

Published on 03 Sep 2025

Increased serum anti-ceramide antibodies and decreased sphingosine-1-phosphate levels in patients with obstructive sleep apnea syndrome as potential markers of endothelial dysfunction

in Molecular Diagnostics and Therapeutics

Andrzej Wiśniewski
Elżbieta Wiśniewska
Łukasz Lewandowski
Izabela Nowak
Monika Kosacka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644828

2,377 views
1 citation

Original Research

Published on 03 Sep 2025

Local sequence context at KRAS codons modulates DNA repair efficiency: insights from molecular dynamics simulations

in Biological Modeling and Simulation

James Davies
Georgina E. Menzies

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1654434

2,166 views

Review

Published on 02 Sep 2025

Phytonutrients and their neuroprotective role in brain disorders

in Micronutrient Biology

Krishnendu Adhikary
Krishnendu Ganguly
Riya Sarkar
Md. Abubakar
Pradipta Banerjee
Prithviraj Karak

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607330

6,142 views
8 citations

Original Research

Published on 02 Sep 2025

The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

in Molecular Diagnostics and Therapeutics

Li-Yuan Yang
Li-Peng Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1660379

1,986 views

Correction

Published on 01 Sep 2025

Correction: Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Roberta Marongiu
Jimcy Platholi
Laibaik Park
Fangmin Yu
Garrett Sommer
Clara Woods
Teresa A. Milner
Michael J. Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1684511

1,504 views

Original Research

Published on 01 Sep 2025

Gut microbiota-metabolome remodeling associated with low bone mass: an integrated multi-omics study in fracture patients

in Molecular Diagnostics and Therapeutics

Xian Zhao
Bin Wu
Pengli Han
Zhongyu Wang
Renwei Cao
Shuo Chen
Cheng Cheng
Hongkai Lian
Yejun Zha
Minjuan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1646361

2,732 views
1 citation

Review

Published on 29 Aug 2025

The emerging role of exosomal LncRNAs in chronic fatigue syndrome: from intercellular communication to disease biomarkers

in Molecular Diagnostics and Therapeutics

Lei Wang
Yujia Xu
Xiang Zhong
Guiping Wang
Zijun Shi
Can Mei
Linwanyue Chen
Jianbo Zhan
Jing Cheng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1653627

3,813 views
2 citations

Original Research

Published on 29 Aug 2025

Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol

in Metabolomics

Jiali Liu
Xiaowen Song
Xinni Song
Xinyue Fu
Shufang Niu
Hong Chang
Songli Shi
Meiqing Yang
Ruiqi Zhao
Peng Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607103

3,344 views

Original Research

Published on 29 Aug 2025

LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition

in Metabolomics

Cristina Olivaro
Nerea Núñez
Patricia Basile
América Mederos
Rafael Reyno
Javier Saurina
Oscar Núñez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1646758

1,937 views

Original Research

Published on 29 Aug 2025

Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics

in Metabolomics

Yan-Song Liu
Yu-Yan Long
Jie Liu
Yu-Chen Liu
Shuang Zhang
Yi-Jia Xu
Shu-Yue Fu
Hua Li
Wang-Hua Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1609227

2,677 views

Original Research

Published on 28 Aug 2025

Effects of chemical modifications on hemoglobin’s toxicity towards human cardiac myocytes

in Bioenergetics

Sirsendu Jana
Haley Garbus-Grant
Tigist Kassa
Abdu I. Alayash

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648209

4,040 views

Editorial

Published on 28 Aug 2025

Editorial: Plasticity of the haematopoietic niche: from embryonic development to aging and disease

in Cellular Biochemistry

Rio Sugimura
Antonella Fidanza
Emanuele Azzoni
Giovanni Canu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683902

2,644 views
2 citations

Original Research

Published on 26 Aug 2025

Insights into the protein ubiquitinome in the host‒pathogen interplay during Mycobacterium tuberculosis infection

in Cellular Biochemistry

Qishun Feng
Qiao Lin
Guoxin Huang
Siqi Li
Yating Xu
Taosheng Ye
Guoliang Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1613454

2,917 views

Original Research

Published on 22 Aug 2025

The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

in Molecular Diagnostics and Therapeutics

Zixiang Liu
Pengpeng Li
Yuanhai Zhang
Shidi Zhao
Wei Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1635795

2,254 views

Original Research

Published on 22 Aug 2025

Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach

in Metabolomics

Christian Ayala-Ortiz
Moira Hough
Elizabeth K. Eder
David W. Hoyt
Rosalie K. Chu
Jason Toyoda
Steven J. Blazewicz
Patrick M. Crill
Ruth Varner
Scott R. Saleska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621357

2,679 views
1 citation

Original Research

Published on 22 Aug 2025

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

in Metabolomics

Siyin Li
Juan Shi
Xiaofang Shu
Xuemin Jian
Jinmei Zou
Jing Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1632244

2,459 views

Review

Published on 21 Aug 2025

Artificial intelligence in primary aldosteronism: current achievements and future challenges

in Molecular Diagnostics and Therapeutics

Yisi Xu
Benjin Liu
Xuqi Huang
Xudong Guo
Ning Suo
Shaobo Jiang
Hanbo Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1660588

6,973 views

Review

Published on 20 Aug 2025

Molecular mechanisms and therapeutic advances of peritubular capillary neogenesis in acute kidney injury

in Molecular Diagnostics and Therapeutics

Yuming Ding
Linmei Gao
Yi Chen
Yanheng Qiao
Bo Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643838

3,354 views
1 citation

Original Research

Published on 20 Aug 2025

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

in Molecular Diagnostics and Therapeutics

Claudia Desireé Norzagaray-Valenzuela
Marco Antonio Valdez-Flores
Josue Camberos-Barraza
Alberto Kousuke De la Herrán-Arita
Juan Fidel Osuna-Ramos
Javier Magaña-Gómez
Carla Angulo-Rojo
Alma Marlene Guadrón-Llanos
Katia Aviña-Padilla
Loranda Calderón-Zamora

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621413

3,032 views

Original Research

Published on 20 Aug 2025

Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases

in Molecular Diagnostics and Therapeutics

Haimei Qi
Haijun Chen
Zhuling Zhang
Jinhui Gan
Huifeng Liu
Xianping Yuan
Fuyu Luo
Junkun Chen
Shichun Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1645223

3,347 views
1 citation

Review

Published on 20 Aug 2025

The role of USP36 in ribosome biogenesis and other pathophysiological processes

in Cellular Biochemistry

Linxin Shao
Mengqi Guo
Qianrui Kou
Ya Guo
Xin Li
Fang Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1650908

2,697 views

Original Research

Published on 20 Aug 2025

Identification of kidney renal clear cell carcinoma prognosis based on gene expression and clinical information

in Molecular Diagnostics and Therapeutics

Xiong Zou
Xi Chen
Jianjun Yang
Yanfeng Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1630250

1,951 views

Review

Published on 20 Aug 2025

Pioneering contribution of Professor Bruce Ames to early development in biochemical aspects of oxidatively generated damage to DNA

in Cellular Biochemistry

Jean Cadet
J. Richard Wagner

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1636255

2,225 views
1 citation

Correction

Published on 18 Aug 2025

Correction: Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin

in Protein Biochemistry for Basic and Applied Sciences

Eman Ibrahem
Ali Osman
Hefnawy Taha
Mohamed F. Abo El-Maati
Basel Sitohy
Mahmoud Sitohy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1660539

1,365 views

5,873 articles

articles

Increased serum anti-ceramide antibodies and decreased sphingosine-1-phosphate levels in patients with obstructive sleep apnea syndrome as potential markers of endothelial dysfunction

Local sequence context at KRAS codons modulates DNA repair efficiency: insights from molecular dynamics simulations

Phytonutrients and their neuroprotective role in brain disorders

The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

Correction: Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

Gut microbiota-metabolome remodeling associated with low bone mass: an integrated multi-omics study in fracture patients

The emerging role of exosomal LncRNAs in chronic fatigue syndrome: from intercellular communication to disease biomarkers

Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol

LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition

Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics

Effects of chemical modifications on hemoglobin’s toxicity towards human cardiac myocytes

Editorial: Plasticity of the haematopoietic niche: from embryonic development to aging and disease

Insights into the protein ubiquitinome in the host‒pathogen interplay during Mycobacterium tuberculosis infection

The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

Artificial intelligence in primary aldosteronism: current achievements and future challenges

Molecular mechanisms and therapeutic advances of peritubular capillary neogenesis in acute kidney injury

Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension

Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases

The role of USP36 in ribosome biogenesis and other pathophysiological processes

Identification of kidney renal clear cell carcinoma prognosis based on gene expression and clinical information

Pioneering contribution of Professor Bruce Ames to early development in biochemical aspects of oxidatively generated damage to DNA

Correction: Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin