Frontiers in Molecular Biosciences

Original Research

Published on 14 Feb 2025

An unfolded protein response (UPR)-signature regulated by the NFKB–miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer

in Molecular Diagnostics and Therapeutics

Jian Zhang
Xiaosong Fan
Yu Chen
Yichao Han
Weixing Yu
Shaolin Zhang
Bicheng Yang
Junlong Zhang
Yanling Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542650

1,564 views

Original Research

Published on 14 Feb 2025

Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics

in Biological Modeling and Simulation

Peetha Vanaja
N. S. Hari Narayana Moorthy
Vivek Singh Rajpoot
Harshawardhan Rao
Rohit Kumar Goswami
Paranthaman Subash
Sulekha Khute
Kareti Srinivasa Rao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1543939

2,880 views
3 citations

Original Research

Published on 14 Feb 2025

A CRISPR-Cas-based recombinase polymerase amplification assay for ultra-sensitive detection of active Trypanosoma brucei evansi infections

in Molecular Diagnostics and Therapeutics

Andrés Álvarez-Rodríguez
Zeng Li
Bo-Kyung Jin
Benoit Stijlemans
Peter Geldhof
Stefan Magez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1512970

2,003 views

Editorial

Published on 13 Feb 2025

Editorial: Omics in endocrinology: from biomarker discovery to targeting therapeutic strategies

in Metabolomics

Michele Costanzo
Shereen M. Aleidi
Anas Abdel Rahman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567250

1,061 views

Original Research

Published on 13 Feb 2025

Blood pressure improvement after resection of non-functioning adrenal adenomas: influencing factors and serum metabolic features

in Metabolomics

Jianlei Zhang
Peiqiang Wu
Yule Chen
Min Wang
Wenbin Song

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524121

1,244 views

Original Research

Published on 13 Feb 2025

Long-term iron supplementation in four patients with X-linked erythropoietic protoporphyria: associations with serum proteins and erythrocyte protoporphyrin levels—a single-centre retrospective study

in Protein Biochemistry for Basic and Applied Sciences

Anna-Elisabeth Minder
Francesca Granata
Franziska van Breemen
Xiaoye Schneider-Yin
Elisabeth I. Minder
Lanja Saleh
Jasmin Barman-Aksözen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1509803

1,146 views

Original Research

Published on 13 Feb 2025

Calcium-dependent adhesion protein CDH18, a potential biomarker for prognosis in uterine corpus endometrial carcinoma

in Molecular Diagnostics and Therapeutics

Xiaoxuan Tang
Shanxing Dang
Jie Qiu
Ruilan Zhou
Jing Ling
Limei Zhang
Xiaopeng Peng
Qingyun Li
Jin Liu
Wei Liao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530253

2,070 views

Original Research

Published on 11 Feb 2025

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

in Molecular Diagnostics and Therapeutics

Hongshuang Su
Xiaoxi Lin
Ayinuer Paredong
Congcong Yao
Yan Zhang
Mengke Geng
Yuqian Guan
Lichao Gong
Feng Jiang
Qi Lv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538526

2,474 views
2 citations

Original Research

Published on 11 Feb 2025

Simulations of pH and thermal effects on SARS-CoV-2 spike glycoprotein

in Biological Modeling and Simulation

Ziyuan Niu
Georgios Kementzidis
Miriam Rafailovich
Marcia Simon
Evangelos Papadopoulos
Bertal H. Aktas
Yuefan Deng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1545041

1,149 views
1 citation

Original Research

Published on 11 Feb 2025

Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer

in Molecular Diagnostics and Therapeutics

Angelica Nogueira Rodrigues
Andreza Karine de Barros Almeida Souto
Diocésio Alves Pinto de Andrade
Larissa Müller Gomes
Sandra Satie Koide
Renata de Godoy e Silva
Bruno Batista de Souza
Juliana Doblas Massaro
Andréia Cristina de Melo
Andrea Morais Borges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524594

1,756 views

Editorial

Published on 10 Feb 2025

Editorial: The emerging role of protein methylation/demethylation modification in disease and homeostasis

in Cellular Biochemistry

Yan-Jun Liu
Jian-Fei Lu
Xin Peng
Guan-Jun Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1565598

891 views

Original Research

Published on 07 Feb 2025

Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling

in Molecular Diagnostics and Therapeutics

Oleksandr Dudin
Ozar Mintser
Vitalii Gurianov
Nazarii Kobyliak
Denys Kozakov
Sofiia Livshun
Oksana Sulaieva

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1543148

1,513 views

Original Research

Published on 07 Feb 2025

Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models

in Cellular Biochemistry

Sébastien Soubeyrand
Paulina Lau
Ruth McPherson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548582

1,463 views

Original Research

Published on 07 Feb 2025

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

in Molecular Diagnostics and Therapeutics

Jihye Chung
Jang Woo Ha
Yong-Beom Park
Sang-Won Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549454

1,403 views

Original Research

Published on 06 Feb 2025

Construction of a circadian rhythm-related gene signature for predicting the prognosis and immune infiltration of breast cancer

in Cellular Biochemistry

Lin Ni
He Li
Yanqi Cui
Wanqiu Xiong
Shuming Chen
Hancong Huang
Zhiwei Wang
Hu Zhao
Bing Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1540672

1,835 views

Original Research

Published on 06 Feb 2025

Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage

in Molecular Diagnostics and Therapeutics

Xiang Chu
Xiyan Zhu
Honghao Xu
Wenbing Zhao
Debin Guo
Xing Chen
Jinze Wu
Lei Li
Hao Wang
Jun Fei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1492729

1,419 views