Frontiers in Molecular Biosciences

Original Research

Published on 01 Aug 2025

Prognostic value of positive lymph node ratio, tumor deposit, and perineural invasion in advanced colorectal signet-ring cell carcinoma

in Molecular Diagnostics and Therapeutics

Liang Chu
Han Wang
Tao Ling
Shuhan Feng
Yucheng Ding
Yan Zhang
Ying Pan
Cenzhu Wang
Xiaohong Wang
Lei Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1617787

1,830 views

Original Research

Published on 01 Aug 2025

Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification

in Glycoscience

Frania J. Zuniga-Banuelos
Greta Lemke
Marcus Hoffmann
Udo Reichl
Erdmann Rapp

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595173

3,514 views
1 citation

Review

Published on 31 Jul 2025

Arfs on the Golgi: four conductors, one orchestra

in Molecular Recognition

Selma Yilmaz Dejgaard
John F. Presley

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1612531

3,335 views
3 citations

Review

Published on 30 Jul 2025

Tools to study microbial iron homeostasis and oxidative stress: current techniques and methodological gaps

in Metabolomics

Patryk Strzelecki
Dariusz Nowicki

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1628725

4,638 views
5 citations

Original Research

Published on 30 Jul 2025

DFusMol: predicting molecular properties based on dual-channel attention

in Molecular Biophysics

Xuan Liu
Wei Du
Haibao Tang
Yingjian Gu
Zhibang Li
Xiaoyang Fu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1623620

2,190 views

Original Research

Published on 30 Jul 2025

Inhibition of BRD4 prevents peribronchial fibrosis in mice with cutaneous lewisite exposure

in Molecular Diagnostics and Therapeutics

Huaxiu Zeng
Pooja Singh
Rajesh Sinha
Crystal T. Stephens
Aftab Ahmad
Mohammad Athar
Veena B. Antony

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644792

2,349 views

Original Research

Published on 29 Jul 2025

Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation

in Molecular Diagnostics and Therapeutics

Xicheng Hu
Zhen Wang
Liyan Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1647796

3,383 views
1 citation

Brief Research Report

Published on 28 Jul 2025

AvaII senses m6A and inosine sites and enables targeted nanopore direct RNA-sequencing

in RNA Networks and Biology

Isabel S. Naarmann-De Vries
Tim Preissendörfer
Julian König
Christoph Dieterich

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593637

2,449 views

Original Research

Published on 28 Jul 2025

Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence

in Molecular Diagnostics and Therapeutics

Juan Chen
Lili Fu
Mengjin Li
Kun Xie
Xinming Li
Xu-jie Zhou
Li Yang
Liming Zhang
Cheng Xue
Zhiguo Mao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1627534

2,722 views
2 citations

Editorial

Published on 25 Jul 2025

Editorial: Understanding the mechanism of dynamic cell communications: a much needed angle for cell motility and barrier functions

in Cellular Biochemistry

Virag Vas
Zhen Xu
Pasquale Cervero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1663453

1,656 views

Opinion

Published on 25 Jul 2025

Immune surveillance as a pharmacological target in the early stages of cancer

in Molecular Diagnostics and Therapeutics

Hongfei Jiang
Zhun Wei
Haibo Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643024

3,871 views
1 citation

Correction

Published on 25 Jul 2025

Correction: Neural stem cell-derived extracellular vesicles: mini players with key roles in neurogenesis, immunomodulation, neuroprotection and aging

in Cellular Biochemistry

Valentina Bonetto
Mariagrazia Grilli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1667664

920 views

Original Research

Published on 23 Jul 2025

Cerium oxide nanoparticles attenuates fibrosis and inflammation in thyroid-associated ophthalmopathy via JNK pathway

in Nanobiotechnology

Bo-Wen Wang
Ru Zhu
Ying Jin
Xuan Ouyang
Fa-Gang Jiang
Xing-Hua Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580062

2,262 views

Original Research

Published on 23 Jul 2025

Maternal plasma microRNA profiles in twin-twin transfusion syndrome and normal monochorionic twin pregnancies

in Molecular Diagnostics and Therapeutics

Steven T. Papastefan
Morgan M. Langereis
Catherine R. Redden
Daniel R. Liesman
Cassandra B. Huerta
Lucas E. Turner
Hee Kap Kang
Bethany T. Stetson
Katherine C. Ott
William S. Marriott

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597215

1,942 views
1 citation

Original Research

Published on 22 Jul 2025

TOP2A as a prognostic biomarker in small cell carcinoma of the esophagus: an integrated bioinformatics and immunohistochemical study

in Molecular Diagnostics and Therapeutics

Xiaolei Yin
Xiaopeng Li
Lili Mi
Jiaojiao Hou
Fei Yin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1640881

1,706 views

Review

Published on 22 Jul 2025

Deuterium trafficking, mitochondrial dysfunction, copper homeostasis, and neurodegenerative disease

in Cellular Biochemistry

Stephanie Seneff
Anthony M. Kyriakopoulos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1639327

4,637 views
2 citations

Original Research

Published on 21 Jul 2025

RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study

in RNA Networks and Biology

Nurul Iffah Mohd Isa
Aslah Nabilah Abdull Sukor
Saiful Effendi Syafruddin
Mohd Faizal Ahmad
Shahidee Zainal Abidin
Mohd Helmy Mokhtar
Azizah Ugusman
Adila A. Hamid

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1520101

2,863 views

Original Research

Published on 18 Jul 2025

Dynamic contrast-enhanced MRI-based radiomics model of intra-tumoral kinetic heterogeneity for predicting breast cancer molecular subtypes

in Molecular Diagnostics and Therapeutics

Yue Cheng
Ran Ren
Yu Xu
Shaofeng Duan
Jilei Zhang
Zhongyuan Bao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1635296

2,355 views
1 citation

Review

Published on 17 Jul 2025

The role of epigenetics in pulmonary fibrosis: recent advances in mechanistic insights and therapeutic implications

in Molecular Diagnostics and Therapeutics

Jingru Huang
Jianfeng Qin
Yuguang Zhu
Ao Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1647300

3,461 views
2 citations

Original Research

Published on 17 Jul 2025

Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics

in Molecular Diagnostics and Therapeutics

Xi Chen
Elizabeth A. Grimm
Yong Qin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1637230

1,867 views

Original Research

Published on 17 Jul 2025

Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect

in Cellular Biochemistry

Charlotte de Ceuninck van Capelle
Leo Luo
Alexander Leitner
Stefan A. Tschanz
Philipp Latzin
Sebastian Ott
Tobias Herren
Loretta Müller
Takashi Ishikawa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593810

3,190 views
3 citations

Review

Published on 16 Jul 2025

An overview of current research on the modulation of NLRP3 inflammasome by traditional Chinese medicine to combat acute pancreatitis

in Cellular Biochemistry

Xiongjie He
Jia Xia
Qi Chen
Zhaozhao Huang
Juanjuan Lu
Yisong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1634132

2,706 views

Original Research

Published on 16 Jul 2025

Identification and validation of integrated stress-response-related genes as biomarkers for age-related macular degeneration

in Molecular Diagnostics and Therapeutics

Jingyi Niu
Ling Jin
Yijun Hu
Yiting Wang
Xiaoning Hao
Wenwen Geng
Ruirui Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583237

2,344 views
1 citation

Brief Research Report

Published on 15 Jul 2025

An integrated approach for analyzing spatially resolved multi-omics datasets from the same tissue section

in Molecular Diagnostics and Therapeutics

Thao Tran
Felicia Wee
Craig Ryan Joseph
Wanqiu Zhang
Jeffrey Chun Tatt Lim
Zhen Wei Neo
Li Yen Chong
Francis Hong Xin Yap
Nathan Heath Patterson
Marc Claesen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614288

7,798 views
1 citation