Frontiers in Molecular Biosciences

Review

Published on 23 Jan 2026

S100A12 drives inflammatory and metabolic reprogramming in sepsis-associated acute kidney injury

in Molecular Diagnostics and Therapeutics

Huanqin Liu
Yanan Lv
Qingjie Xue
Jikui Shi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1741799

774 views

Review

Published on 23 Jan 2026

Advances in protein dot blot: principles, technical specifics, applications, and future perspectives

in Protein Biochemistry for Basic and Applied Sciences

Juan Lu
Feng-yi Mai
Xin-yu Li
Wen-tao Yang
Jing-rong Liang
Xing-long Li
Jie Guo
Chen-guang Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1768231

1,021 views

Original Research

Published on 23 Jan 2026

Investigating circulating expression profile for H19, MEG3, and MIAT long noncoding RNAs with miR-135a and miR-29a in chronic kidney disease and renal hemodialysis patients: interrelations with serum sclerostin

in RNA Networks and Biology

Marwa A. Dahpy
Marwa K. Khairallah
Rania Naguib
Mona A. Khalil
Salwa Seif Eldin
Marwa A. Sabet
Amira A. Kamel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1703108

648 views

Original Research

Accepted on 22 Jan 2026

Genetic Constraints on Protein Loop Evolution: Out-of-Frame Stop Codons limit Bacillus subtilis Stationary-phase mutagenesis

in Genome Organization and Dynamics

Carmen Vallin
Mario Pedraza-Reyes
Eduardo A Robleto

Frontiers in Molecular Biosciences

189 views

Original Research

Accepted on 22 Jan 2026

Deciphering Skeletal Muscle Trait Differences Between Chinese a nd Western Pig Breeds Based on 4D-label Ubiquitin-Proteomics

in Protein Biochemistry for Basic and Applied Sciences

Yunlei Li
Zikai AI
Yun Zhang
Mingfu Xiong
Jingyang DONG
Yilong YAO
Yaxing LIU
Jian LI
Yongjin ZHANG
Xinhao FAN

Frontiers in Molecular Biosciences

152 views

Methods

Accepted on 21 Jan 2026

Quantum Chemical Profiling of Protein Mutations via Fragment-Based DFT

in Biological Modeling and Simulation

Alejandro Leyva
Muhammed Khalid Khan Niazi

Frontiers in Molecular Biosciences

251 views

Review

Accepted on 21 Jan 2026

Heterogeneous Regulation of Fibroblast Growth Factor 23 in Acute Kidney Injury, Chronic Kidney Disease, and Polycystic Kidney Disease: Mechanisms, Diagnostic Utility, and Clinical Implications

in Molecular Diagnostics and Therapeutics

Xiaohua Hu
Bo Yang
Nanmei Liu
Haimin Chen
Min Min
Cheng Xue

Frontiers in Molecular Biosciences

182 views

Original Research

Accepted on 20 Jan 2026

Predicting Drug–Drug Interactions Between Ayahuasca Alkaloids and SSRIs Using Physiologically Based Pharmacokinetic Modeling

in Biological Modeling and Simulation

Gabriella de Souza Gomes Ribeiro
Beatriz Aparecida Passos Bismara Paranhos
Fabiane Dörr
Mauricio Yonamine
Bianca Villanova
Lorena Terene Lopes Guerra
Adrieli Oliveira Raminelli
Jose Augusto Silva Reis
Caio Cesar de Paula
Anna Beatriz Vicentini Zacharias

Frontiers in Molecular Biosciences

442 views

Original Research

Published on 20 Jan 2026

Gene expression profiling identifies ferroptosis-related genes and pathways in human colon cancers cell lines

in Molecular Diagnostics and Therapeutics

M. Balik-Meisner
D. Phadke
D. Mav
R. Shah
K. R. Shockley
Carri Murphy
Erik J. Tokar
Birandra K. Sinha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1680206

917 views

Original Research

Accepted on 19 Jan 2026

Spinal cord injury–induced overflow incontinence reshapes the activin–follistatin–inhibin axis in mouse bladder and kidney

in Cellular Biochemistry

Yucheng Shen
Shengkai Yang
Hai Zhou
Yongkun Zhu
Zhong Wang
Weimin Jiang

Frontiers in Molecular Biosciences

265 views

Editorial

Published on 19 Jan 2026

Editorial: Molecular mechanisms and precision medicine in rare diseases

in Cellular Biochemistry

Hector Rodriguez Cetina Biefer
Abdallah Elkhal
Mohamed Taha Moutaoufik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1778169

1,057 views

Original Research

Published on 16 Jan 2026

The predictive role of protease-activated receptor (PAR-1) polymorphisms and activated microplatelets on the severity of atherosclerosis – preliminary studies

in Molecular Diagnostics and Therapeutics

Urszula Jakobsche-Policht
Agnieszka Bronowicka-Szydełko
Rajmund Adamiec
Dorota Bednarska-Chabowska
Łukasz Lewandowski
Rafał Małecki
Kinga Gostomska-Pampuch
Joanna Adamiec-Mroczek
Marta Myszka-Kozłowska
Dagmara Baczyńska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1662954

867 views

Original Research

Published on 16 Jan 2026

Single-cell multi-omics sequencing reveals the immunological disturbance underlying Kawasaki disease

in Molecular Diagnostics and Therapeutics

Xue Fan
Shuang Deng
Yuehao Xu
Bin Wang
Xin Guo
Jinwen Liao
Mingguo Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1758948

910 views

Original Research

Published on 16 Jan 2026

Alterations in protein N-glycosylation confer vanadate resistance in Ogataea polymorpha mutants defective in phosphomannosylation

in Glycoscience

Maria Pakhomova
Azamat Karginov
Maria Kulakova
Polina Vladimirova
Olga Mitkevich
Michael Agaphonov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1741711

588 views

Original Research

Accepted on 15 Jan 2026

A label-free microLC-SWATH-MS methodology with immunoaffinity depletion of high abundant serum proteins for quantitative proteomic comparison of fresh-frozen human normal breast tissue and tumor clinical specimens

in Molecular Diagnostics and Therapeutics

Katarzyna Macur
Aleksandra Ewa Bogucka
Anna Fel-Tukalska
Jarosław Skokowski
Stanisław Ołdziej
Paulina Czaplewska

Frontiers in Molecular Biosciences

411 views

Original Research

Accepted on 15 Jan 2026

Sex-based antibody subclass maturation drives direct enzymatic inhibition in Fabry disease patients receiving enzyme replacement therapy

in Molecular Diagnostics and Therapeutics

Tomas Baldwin
Hibba Kurdi
Ivan Doykov
Stefania Rosmini
Sabrina Nordin
Joao Bicho Augusto
Rebecca Kozor
Julien Colomban Baruteau
James Davison
David Moreno-Martinez

Frontiers in Molecular Biosciences

239 views

Review

Published on 15 Jan 2026

Target temperature management in acute ischemic stroke

in Molecular Diagnostics and Therapeutics

Lan Gao
Ting Yang
Hong Chong
Longfei Wu
Jinming Han

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1728769

979 views

Review

Published on 15 Jan 2026

Regulatory QTLs affecting miRNA-mRNA interactions in cancer: mechanisms, methods, and clinical implications

in Cellular Biochemistry

Vivek Kumar
Rohit Shukla
Amit Chaudhary
Mansi Gautam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1749396

1,208 views

Original Research

Published on 15 Jan 2026

A novel tumor-progressing fibroblast signature derived from single-cell RNA sequencing enables prognostic stratification and reveals RNF11 as a functional regulator in bladder cancer

in Molecular Diagnostics and Therapeutics

Miaoyu Zhang
Liangbin Lin
He Xu
Xu Su
Kui Zeng
Fangyang Zhong
Xianchao Su
Jie Chen
Min Cao
Hui Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1722809

947 views

Original Research

Published on 15 Jan 2026

Exploring the risk stratification of carotid plaque hemodynamic using four-dimensional blood flow technology

in Molecular Diagnostics and Therapeutics

Si-yuan Zhang
Hong-liang Zhao
Xiao-wei Song
Jian Wu
Rui Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1685377

798 views

Brief Research Report

Published on 15 Jan 2026

CSDE1 stabilizes AGO2 in embryonic stem cells

in RNA Networks and Biology

Yuguan Jiang
Mason Waye
Pavan Kumar Kakumani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1745258

933 views

Review

Accepted on 14 Jan 2026

Catalpol: An natural multifunctional iridoid glycoside with promising therapeutic properties

in Cellular Biochemistry

Guannan He
Jing Song
Ruixuan Ma
Yixing Zhou
Yamin Xue
Fa-Rong Zhang

Frontiers in Molecular Biosciences

251 views

Review

Published on 14 Jan 2026

Origin of the clock in Neurospora crassa

in Nanobiotechnology

Ahmad Al-Omari
Cara Altimus
Jonathan Arnold
Sam Arsenault
Suchendra Bhandarkar
Shishir Bhusal
Christian Caranica
Jia Hwei Cheong
Zhaojie Deng
Arthur S. Edison

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1697003

1,552 views

Review

Accepted on 13 Jan 2026

Roles of Mitochondrial Complexes in Non-Alcoholic Fatty Liver Disease

in Mitochondria in Physiology and Disease

kai wang
li wang
jiamin ning
Dexin Li

Frontiers in Molecular Biosciences

303 views

5,864 articles

articles

S100A12 drives inflammatory and metabolic reprogramming in sepsis-associated acute kidney injury

Advances in protein dot blot: principles, technical specifics, applications, and future perspectives

Investigating circulating expression profile for H19, MEG3, and MIAT long noncoding RNAs with miR-135a and miR-29a in chronic kidney disease and renal hemodialysis patients: interrelations with serum sclerostin

Genetic Constraints on Protein Loop Evolution: Out-of-Frame Stop Codons limit Bacillus subtilis Stationary-phase mutagenesis

Deciphering Skeletal Muscle Trait Differences Between Chinese a nd Western Pig Breeds Based on 4D-label Ubiquitin-Proteomics

Quantum Chemical Profiling of Protein Mutations via Fragment-Based DFT

Heterogeneous Regulation of Fibroblast Growth Factor 23 in Acute Kidney Injury, Chronic Kidney Disease, and Polycystic Kidney Disease: Mechanisms, Diagnostic Utility, and Clinical Implications

Predicting Drug–Drug Interactions Between Ayahuasca Alkaloids and SSRIs Using Physiologically Based Pharmacokinetic Modeling

Gene expression profiling identifies ferroptosis-related genes and pathways in human colon cancers cell lines

Spinal cord injury–induced overflow incontinence reshapes the activin–follistatin–inhibin axis in mouse bladder and kidney

Editorial: Molecular mechanisms and precision medicine in rare diseases

The predictive role of protease-activated receptor (PAR-1) polymorphisms and activated microplatelets on the severity of atherosclerosis – preliminary studies

Single-cell multi-omics sequencing reveals the immunological disturbance underlying Kawasaki disease

Alterations in protein N-glycosylation confer vanadate resistance in Ogataea polymorpha mutants defective in phosphomannosylation

A label-free microLC-SWATH-MS methodology with immunoaffinity depletion of high abundant serum proteins for quantitative proteomic comparison of fresh-frozen human normal breast tissue and tumor clinical specimens

Sex-based antibody subclass maturation drives direct enzymatic inhibition in Fabry disease patients receiving enzyme replacement therapy

Target temperature management in acute ischemic stroke

Regulatory QTLs affecting miRNA-mRNA interactions in cancer: mechanisms, methods, and clinical implications

A novel tumor-progressing fibroblast signature derived from single-cell RNA sequencing enables prognostic stratification and reveals RNF11 as a functional regulator in bladder cancer

Exploring the risk stratification of carotid plaque hemodynamic using four-dimensional blood flow technology

CSDE1 stabilizes AGO2 in embryonic stem cells

Catalpol: An natural multifunctional iridoid glycoside with promising therapeutic properties

Origin of the clock in Neurospora crassa

Roles of Mitochondrial Complexes in Non-Alcoholic Fatty Liver Disease