Frontiers in Molecular Biosciences

Original Research

Published on 12 May 2025

Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data

in Genome Organization and Dynamics

Lian Duan
Mahshad Hashemi
Alioune Ngom
Luis Rueda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547231

1,336 views

Original Research

Published on 12 May 2025

New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics

in Molecular Diagnostics and Therapeutics

Xue Fan
Ying Li
Yuehao Xu
Jianqing Lin
Xin Guo
Jinwen Liao
Mingguo Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597412

1,072 views

Review

Published on 12 May 2025

The significance of calcium ions in cerebral ischemia-reperfusion injury: mechanisms and intervention strategies

in Molecular Diagnostics and Therapeutics

Yong-Wang Li
Yu Liu
Sheng-Zhen Luo
Xiao-Juan Huang
Yan Shen
Wei-Si Wang
Zhi-Chen Lang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585758

880 views

Review

Published on 09 May 2025

Heat shock proteins in hypothermia: a review

in Cellular Biochemistry

Shang-Jin Song
Guo-Cheng Wu
Li Yi
Xin Liu
Ming-Min Jiang
Xiao-Chen Zhang
Zi-Fei Yin
Wei Gu
Yi Ruan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1564364

1,152 views

Original Research

Published on 09 May 2025

Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study

in Metabolomics

Carlos A. R. Sánchez
Daniel Pardo-Rodriguez
Erica Mancera-Soto
Lizeth León
Dailson Paulucio
Angelo D’Alessandro
Caleb G. M. Santos
Edgar Cristancho
Gustavo Monnerat
Diana M. Ramos-Caballero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1571103

1,484 views

Correction

Published on 09 May 2025

Corrigendum: Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats

in Cellular Biochemistry

Maha Abdullah Alwaili
Amal S. Abu-Almakarem
Salwa Aljohani
Sahar Abdulrahman Alkhodair
Maha M. Al-Bazi
Thamir M. Eid
Jehan Alamri
Maysa A. Mobasher
Norah K. Algarzae
Arwa Ishaq A. Khayyat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1601841

686 views

Review

Published on 09 May 2025

Engineered exosomes: a promising drug delivery platform with therapeutic potential

in Molecular Diagnostics and Therapeutics

Genevieve Schwarz
Xuechen Ren
Wen Xie
Haitao Guo
Yong Jiang
Jinyu Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583992

1,906 views
1 citation

Original Research

Published on 08 May 2025

Identification of biomarkers and immune microenvironment associated with heart failure through bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Jingyun Jin
Shuyan Qin
Qiang Fu
Changzhi Yu
Hongjin Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580880

1,987 views

Original Research

Published on 08 May 2025

Untargeted metabolomics for acute intra-abdominal infection diagnosis in serum and urine using UHPLC-TripleTOF MS

in Metabolomics

Zhenhua Dong
Shaopeng Zhang
Hongwei Zhang
Dingliang Zhao
Ziwen Pan
Daguang Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1534102

1,081 views

Review

Published on 08 May 2025

Role of miRNA in adult ocular tumorigenesis

in RNA Networks and Biology

Arianna Romani
Elisabetta Melloni
Giada Lodi
Francesca Bompan
Rebecca Foschi
Enrico Zauli
Elena Pozza
Paola Secchiero
Giorgio Zauli
Maurizio Previati

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1459761

1,058 views

Original Research

Published on 06 May 2025

Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis

in Molecular Diagnostics and Therapeutics

Zhenwei Xie
Cheng Feng
Yude Hong
Libo Chen
Mingyong Li
Weiming Deng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1587196

1,361 views

Original Research

Published on 06 May 2025

Exploring focal adhesion data: dynamic parameter extraction from FRAP and FLAP experiments using chemical master equation

in Biological Modeling and Simulation

Luciana Renata de Oliveira
Matheus Gimenez Fernandes
José Salvatore Leister Patane
Jean-Marc Schwartz
José Eduardo Krieger
Christoph Ballestrem
Ayumi Aurea Miyakawa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1587608

1,081 views

Review

Published on 02 May 2025

Epigenetic modifications in cardiac fibrosis: recent evidence of new pharmacological targets

in Molecular Diagnostics and Therapeutics

Marian Pérez
Mónica Gómez
Jairo Castellar-López
Patricio Araos
Evelyn Mendoza-Torres
Samir Bolívar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583446

1,287 views

Original Research

Published on 01 May 2025

Integrative multi-omics and Mendelian randomization analysis reveal SPP1+ tumor-associated macrophage-driven prognostic signature for hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Kai Lei
Yichun Lei
Zeyao Wang
Zhixin Ye
Jiawei Liu
Wenhao Chen
Caihong Zhou
Jinmei Tan
Shuxian Chen
Yifan Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1594610

2,320 views
1 citation

Original Research

Published on 01 May 2025

Predictive value of CPS combined with inflammatory markers for pathological remission of locally advanced head and neck squamous cell carcinoma after adjuvant immunochemotherapy

in Molecular Diagnostics and Therapeutics

Yudong Ning
Han Li
Yixuan Song
Yuqin He
Shaoyan Liu
Yang Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593742

1,091 views
2 citations

Review

Accepted on 30 Apr 2025

Review of Research Progress in Sepsis-Associated Acute Kidney Injury

in Molecular Diagnostics and Therapeutics

Wanning Nian
Weichen Tao
Haiyi Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1603392

252 views