Frontiers in Molecular Biosciences

Editorial

Published on 07 Oct 2025

Editorial: The role of cell metabolism in development, drug resistance, and survival assessment in cancer

in Metabolomics

Kishor Pant
Ashok Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1685924

1,695 views

Brief Research Report

Published on 01 Oct 2025

Paediatric CSF acylcarnitine reference ranges

in Metabolomics

Ontefetse Neo Plaatjie
A. Marceline Tutu Van Furth
Regan Solomons
Martijn Van Der Kuip
Shayne Mason

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643667

2,079 views

Brief Research Report

Published on 26 Sep 2025

Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry

in Metabolomics

Janine F. M. Otto
Georg Pohnert
Thomas Wichard
Michael Bauer
Anne Busch
Nico Ueberschaar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1681568

2,773 views

Original Research

Published on 26 Sep 2025

Lipidomic profiling reveals systemic serum lipid remodeling induced by dexamethasone in mice

in Metabolomics

Aiping Zhang
Zhao Wang
Jianjian Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644637

1,893 views

Original Research

Published on 04 Sep 2025

Comprehensive lipoprotein and glycoprotein characterization in rheumatoid arthritis plasma and association with clinical markers

in Metabolomics

Konstantina Ismini Tsezou
Mohan Ghorasaini
Aswin Verhoeven
Aikaterini Iliou
Dimitra Benaki
Panayiotis G. Vlachoyiannopoulos
Martin Giera
Emmanuel Mikros

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1627273

2,440 views

Original Research

Published on 29 Aug 2025

LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition

in Metabolomics

Cristina Olivaro
Nerea Núñez
Patricia Basile
América Mederos
Rafael Reyno
Javier Saurina
Oscar Núñez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1646758

1,911 views

Original Research

Published on 29 Aug 2025

Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol

in Metabolomics

Jiali Liu
Xiaowen Song
Xinni Song
Xinyue Fu
Shufang Niu
Hong Chang
Songli Shi
Meiqing Yang
Ruiqi Zhao
Peng Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607103

3,330 views

Original Research

Published on 29 Aug 2025

Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics

in Metabolomics

Yan-Song Liu
Yu-Yan Long
Jie Liu
Yu-Chen Liu
Shuang Zhang
Yi-Jia Xu
Shu-Yue Fu
Hua Li
Wang-Hua Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1609227

2,654 views

Original Research

Published on 22 Aug 2025

Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach

in Metabolomics

Christian Ayala-Ortiz
Moira Hough
Elizabeth K. Eder
David W. Hoyt
Rosalie K. Chu
Jason Toyoda
Steven J. Blazewicz
Patrick M. Crill
Ruth Varner
Scott R. Saleska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621357

2,641 views
1 citation

Original Research

Published on 22 Aug 2025

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

in Metabolomics

Siyin Li
Juan Shi
Xiaofang Shu
Xuemin Jian
Jinmei Zou
Jing Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1632244

2,447 views

Original Research

Published on 11 Aug 2025

Targeted urinary metabolomics combined with machine learning to identify biomarkers related to central carbon metabolism for IBD

in Metabolomics

Miao-Lin Lei
Guan-Wei Bi
Xiao-Lin Yin
Yue Wang
Zi-Ru Sun
Xin-rui Guo
Hui-peng Zhang
Xiao-han Zhao
Feng Li
Yan-Bo Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615047

2,544 views

Original Research

Published on 08 Aug 2025

Effects of swimming training on cecum microorganisms and metabolites in rats with high fat diet

in Metabolomics

Chuan Dong
Ling Chen
Dengpan Li
Xuefeng Zhang
Yulong Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1569239

1,553 views

Editorial

Published on 08 Aug 2025

Editorial: Multi-scale systems: ecological approaches to investigate the role of the microbiota in different niches

in Metabolomics

Padhmanand Sudhakar
Kristel Van Steen
Amirul Islam Mallick
Kaline Arnauts

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1665390

1,550 views

Review

Published on 30 Jul 2025

Tools to study microbial iron homeostasis and oxidative stress: current techniques and methodological gaps

in Metabolomics

Patryk Strzelecki
Dariusz Nowicki

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1628725

4,581 views
4 citations

Original Research

Published on 14 Jul 2025

Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures

in Metabolomics

Rongyue Ma
Huangruici Zhang
Weijie Wang
Changping Yu
Guohang Xiong
Qing Li
Yan Wang
Li Zhou
Yu Zhang
Min Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567064

2,403 views

Original Research

Published on 11 Jul 2025

Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery

in Metabolomics

William A. Fountain
Stefano Donega
Nirad Banskota
Ruin Moaddel
Mona Patel
Linda Zukley
Sarah Church
Katie Bustin
Josephine M. Egan
Jeremy Walston

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1613238

2,491 views
1 citation

Review

Published on 09 Jul 2025

Functional metabolomics: unlocking the role of small molecular metabolites

in Metabolomics

Hetao Chen
Jiao Kong
Peipei Du
Qian Wang
Tao Jiang
Xixi Hou
Tingting Feng
Jiajia Duan
Chuanxin Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542100

3,227 views
2 citations

Original Research

Published on 09 Jul 2025

A comprehensive characterization of metabolic signatures—hypoxia, glycolysis, and lactylation—in non-healing diabetic foot ulcers

in Metabolomics

Bo Hu
Xuan Li
Yunfeng Li
Shengnan Chai
Mei Jin
Long Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593390

4,852 views
5 citations

Original Research

Published on 08 Jul 2025

Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics

in Metabolomics

Ji-Peng Liu
Long-Teng Tu
Ke-Zhen Yang
Yin-Yin Li
Yu Gong
Bing-Xuan Han
Chuan Liu
Tian-Qi Xia
Yu Liu
Xiao-Min Hao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1619356

2,697 views

Original Research

Published on 30 Jun 2025

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

in Metabolomics

Shengsheng Li
Shenglan Qi
Rongsheng Li
Fangming Yang
Zhenyi Niu
Wei Liu
Suping Ma
Zhun Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614341

3,420 views
1 citation

Original Research

Published on 18 Jun 2025

Global trends and emerging insights in ocular tumor-associated metabolites: a bibliometric and visualization analysis

in Metabolomics

Subo Cai
Wuping Xu
Dongyi Yu
Yimin Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1572710

2,239 views

Original Research

Published on 18 Jun 2025

Comprehensive clinical and metabolomics profiling of COVID-19 Mexican patients across three epidemiological waves

in Metabolomics

David Alejandro García-López
Joel Monárrez-Espino
Juan Carlos Borrego-Moreno
Jiamin Zheng
Rupasri Mandal
Claudia Torres-Calzada
Juan José Oropeza-Valdez
Alanne Tenório Nunes
Sergio Hugo Sánchez Rodríguez
Jesús Adrián López

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607583

3,283 views

Brief Research Report

Published on 17 Jun 2025

Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry

in Metabolomics

Adrian Bartoszek
Ewa Paszkowska
Anna Kozub-Pędrak
Agata Sumara
Emilia Fornal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549993

2,192 views

Original Research

Published on 17 Jun 2025

Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry

in Metabolomics

Serena Correnti
Giuseppina Fanelli
Mariaimmacolata Preianò
Veronica Lelli
Mariagrazia Tarantino
Annalisa Fregola
Massimo Bitonti
Emanuela Chiarella
Anna Maria Timperio
Sara Rinalducci

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578998

2,446 views

449 articles

articles

Editorial: The role of cell metabolism in development, drug resistance, and survival assessment in cancer

Paediatric CSF acylcarnitine reference ranges

Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry

Lipidomic profiling reveals systemic serum lipid remodeling induced by dexamethasone in mice

Comprehensive lipoprotein and glycoprotein characterization in rheumatoid arthritis plasma and association with clinical markers

LC-HRMS fingerprinting and chemometrics for the characterization and classification of Lotus cultivars from Uruguay: a study on phenolic composition

Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol

Toxicological analysis of metabolites in ischemic stroke based on salivary metabolomics

Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach

Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease

Targeted urinary metabolomics combined with machine learning to identify biomarkers related to central carbon metabolism for IBD

Effects of swimming training on cecum microorganisms and metabolites in rats with high fat diet

Editorial: Multi-scale systems: ecological approaches to investigate the role of the microbiota in different niches

Tools to study microbial iron homeostasis and oxidative stress: current techniques and methodological gaps

Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures

Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery

Functional metabolomics: unlocking the role of small molecular metabolites

A comprehensive characterization of metabolic signatures—hypoxia, glycolysis, and lactylation—in non-healing diabetic foot ulcers

Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

Global trends and emerging insights in ocular tumor-associated metabolites: a bibliometric and visualization analysis

Comprehensive clinical and metabolomics profiling of COVID-19 Mexican patients across three epidemiological waves

Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry

Untargeted metabolomics fingerprints in seminal plasma of patients with abnormal sperm morphology using high-performance liquid chromatography and mass spectrometry