Frontiers in Molecular Biosciences

Original Research

Published on 16 May 2025

Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

in Metabolomics

Junyan Wang
Panpan Sun
Fan Zhang
Yu Xu
Shenghu Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1592888

1,423 views

Original Research

Published on 09 May 2025

Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study

in Metabolomics

Carlos A. R. Sánchez
Daniel Pardo-Rodriguez
Erica Mancera-Soto
Lizeth León
Dailson Paulucio
Angelo D’Alessandro
Caleb G. M. Santos
Edgar Cristancho
Gustavo Monnerat
Diana M. Ramos-Caballero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1571103

1,448 views

Original Research

Published on 08 May 2025

Untargeted metabolomics for acute intra-abdominal infection diagnosis in serum and urine using UHPLC-TripleTOF MS

in Metabolomics

Zhenhua Dong
Shaopeng Zhang
Hongwei Zhang
Dingliang Zhao
Ziwen Pan
Daguang Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1534102

1,071 views

Original Research

Published on 30 Apr 2025

Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice

in Metabolomics

Ying Xie
Zhaoxiang Zeng
Jinrong Zhang
Qiangqiang Han
Chengwu Song
Shuna Jin
Min Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595602

1,476 views

Original Research

Published on 28 Apr 2025

MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma

in Metabolomics

Yan Jiang
Zhengyu Shu
Lei Cheng
Haowei Wang
Taiping He
Liwen Fu
Chao Zhao
Xuefei Li
Weicheng Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1591446

1,658 views

Original Research

Published on 25 Apr 2025

Early potential metabolic biomarkers of T1 stage lung adenocarcinoma based on serum metabolomics

in Metabolomics

Bin Wu
Min Zheng
Qingkui Guo
Ning Wang
Chen Zhu
Wen Zhao
Ye Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1544774

1,304 views

Original Research

Published on 16 Apr 2025

Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry

in Metabolomics

Jia-Hao Li
Jia-Li Liu
Jian-Wen Song
Wei-Liang Deng
Xin-Zhi Cao
Zhong-Wen Wu
Ding-Hao Chen
Hui Wang
Song Yu
Qi Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1563642

1,125 views

Original Research

Published on 09 Apr 2025

High-throughput metabolomics exploring the pharmacological effects and mechanism of icariin on rheumatoid arthritis rat based on ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

in Metabolomics

Peng Zhou
Xixi Liu
Yushi Tian
Shouze Ren
Hua Liang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1514882

1,095 views

Original Research

Published on 09 Apr 2025

Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome

in Metabolomics

Jiaqi Liu
Aiwei Wang
Feng Qi
Xiaoyan Liu
Zhengguang Guo
Haidan Sun
Mindi Zhao
Tingmiao Li
Fei Xue
Hai Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547476

1,177 views

Editorial

Published on 08 Apr 2025

Editorial: Metabolomics in personalized cancer medicine

in Metabolomics

Joana Pinto
Jacopo Troisi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593877

906 views

Original Research

Published on 07 Apr 2025

Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy

in Metabolomics

Ilona Dudka
João Figueira
Pernilla Wikström
Anders Bergh
Gerhard Gröbner

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1426949

1,349 views

Editorial

Published on 28 Mar 2025

Editorial: Metabolomics in human and animal ophthalmic research

in Metabolomics

Diana Anna Dmuchowska
Muhaiyo Bartolo Khodjayeva
Michal Ciborowski

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1594647

814 views

Brief Research Report

Published on 26 Mar 2025

Urinary marker of oxidative stress in children correlates with molecules in exhaled breath

in Metabolomics

Amanda Gisler
Kapil Dev Singh
Andrea Marten
Fabienne Decrue
Urs Frey
Pablo Sinues
Jakob Usemann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1511119

1,088 views

Original Research

Published on 25 Mar 2025

Mass spectrometry-based metabolomics reveal the effects and potential mechanism of isochlorogenic acid A in MC3T3-E1 cells

in Metabolomics

Lian Zhu
Liu Xie
Ziming Wang
Kai-Lin Li
Wei Cai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1518873

1,072 views

Original Research

Published on 20 Mar 2025

A multi-omics reciprocal analysis for characterization of bacterial metabolism

in Metabolomics

Gabriel Santos Arini
Tiago Cabral Borelli
Elthon Góis Ferreira
Rafael de Felício
Paula Rezende-Teixeira
Matheus Pedrino
Franciene Rabiço
Guilherme Marcelino Viana de Siqueira
Luiz Gabriel Mencucini
Henrique Tsuji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1515276

2,140 views

Original Research

Published on 17 Mar 2025

Serum metabolic profiling of patients with diabetic kidney disease based on gas chromatography-mass spectrometry

in Metabolomics

Xueyan Bian
Chenwen Wang
Majie Wang
Ailing Yin
Jiayan Xu
Mijia Liu
Hui Wang
Yating Cao
Xin Huang
Chenxue Qin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1541440

1,057 views