Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Hypothesis and Theory

Accepted on 31 Jan 2025

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

in Molecular Diagnostics and Therapeutics

Xiangyang Wang
Jingxiao Li
Rong Qin
Yi Yin
Jiepin Li
Sitian Lin
Xi Zou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1523494

Review

Published on 31 Jan 2025

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

in Molecular Diagnostics and Therapeutics

Rui Gao
Meilin Liu
Haoyi Yang
Yuhan Shen
Ni Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548355

123 views

Original Research

Accepted on 30 Jan 2025

Q-Der: A Next-Generation CoQ10 Analogue Supercharging Neuroprotection by Combating Oxidative Stress and Enhancing Mitochondrial Function

in Molecular Diagnostics and Therapeutics

Michela Battistelli
Matteo Micucci
Federico Gianfanti
Sabrina DONATI ZEPPA
Giosuè Annibalini
BARBARA CANONICO
fabiana fanelli
ROBERTA SALTARELLI
riham osman
mariele montanari

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1525103

Original Research

Accepted on 30 Jan 2025

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

in Molecular Diagnostics and Therapeutics

Lijun Sun
Xiaoqing Li
Li Yang
Longfei Zhu
Jingying Sun
Xu Cuixiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536477

Original Research

Published on 30 Jan 2025

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling

in Molecular Diagnostics and Therapeutics

Raquel Arantes Megid
Guilherme Gomes Ribeiro
Izabela Natalia Faria Gomes
Ana Carolina Laus
Letícia Ferro Leal
Luciane Sussuchi da Silva
Abu-Bakr Adetayo Ariwoola
Josiane Mourão Dias
Rui Manuel Reis
Renato Jose da Silva-Oliveira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537523

300 views

Original Research

Published on 29 Jan 2025

Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping

in Molecular Diagnostics and Therapeutics

Shaghayegh Soleimani
Ozgur Albayrak
Kayra Somay
Hong Yang
Buket Yigit
Burge Ulukan
Dila Atak
Murat Akyildiz
Metehan Gursoy
Elif Demirtas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1521811

322 views

Original Research

Published on 28 Jan 2025

Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology

in Molecular Diagnostics and Therapeutics

Iryna Omelianenko
Nazarii Kobyliak
Tetyana Falalyeyeva
Oleksii Seleznov
Pavlina Botsun
Lyudmila Ostapchenko
Oleksandr Korotkyi
Liudmyla Domylivska
Olena Tsyryuk
Galyna Mykhalchyshyn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542821

229 views

Mini Review

Published on 28 Jan 2025

Aging, cancer, and autophagy: connections and therapeutic perspectives

in Molecular Diagnostics and Therapeutics

Begoña Zapatería
Esperanza Arias

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1516789

194 views

Original Research

Accepted on 27 Jan 2025

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

in Molecular Diagnostics and Therapeutics

Jihye Chung
Jang Woo Ha
Yong-Beom Park
Sang-Won Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549454

Original Research

Accepted on 27 Jan 2025

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

in Molecular Diagnostics and Therapeutics

Ivana Kurelac
Manuela Sollazzo
Monica De Luise
Francesca Nanetti
Laura Lanteri
Luigi D'Angelo
Beatrice Cavina
Simona Corrà
Stefano Miglietta
Sara Milioni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537407

Review

Accepted on 27 Jan 2025

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

in Molecular Diagnostics and Therapeutics

Yu Zhang
Yanfeng Yi
Yinghao Shu
Xiaochen Ru
Shuaibing He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1528663

Original Research

Accepted on 27 Jan 2025

Calcium-Dependent Adhesion Protein CDH18, a Potential Biomarker for Prognosis in Uterine Corpus Endometrial Carcinoma

in Molecular Diagnostics and Therapeutics

Xiaoxuan Tang
Shanxing Dang
Jie Qiu
Ruilan Zhou
Jing Ling
Limei Zhang
Pengxiao Peng
Qingyun Li
Jin Liu
Wei Liao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530253

Original Research

Accepted on 23 Jan 2025

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

in Molecular Diagnostics and Therapeutics

Hongshuang Su
Xiaoxi Lin
Ayinuer Paredong
Congcong Yao
Yan Zhang
Mengke Geng
Yuqian Guan
Lichao Gong
Feng Jiang
Qi Lv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538526

Retraction

Published on 23 Jan 2025

Retraction: ZFP36 binds with PRC1 to inhibit tumor growth and increase 5-Fu chemosensitivity of hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561889

206 views

Original Research

Published on 23 Jan 2025

Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer

in Molecular Diagnostics and Therapeutics

L. S. Franco
S. Arunachalam
A. Chauhan
S. A. Kareff
P. L. Hallenbeck

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520223

312 views

Original Research

Published on 22 Jan 2025

Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study

in Molecular Diagnostics and Therapeutics

Qiuwan Wei
Yiqing Shen
Yiren Tian
Yunzhi Ling

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1522246

230 views

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Articles

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

Q-Der: A Next-Generation CoQ10 Analogue Supercharging Neuroprotection by Combating Oxidative Stress and Enhancing Mitochondrial Function

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling

Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping

Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology

Aging, cancer, and autophagy: connections and therapeutic perspectives

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

Calcium-Dependent Adhesion Protein CDH18, a Potential Biomarker for Prognosis in Uterine Corpus Endometrial Carcinoma

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

Retraction: ZFP36 binds with PRC1 to inhibit tumor growth and increase 5-Fu chemosensitivity of hepatocellular carcinoma

Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer

Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study