Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 04 Apr 2025

Integrated multi-omics analysis reveals the functional and prognostic significance of lactylation-related gene PRDX1 in breast cancer

in Molecular Diagnostics and Therapeutics

Qinqing Wu
Heng Cao
Jiangdong Jin
Dongxu Ma
Yixiao Niu
Yanping Yu
Xiang Wang
Yiqin Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580622

7,737 views
1 citation

Editorial

Published on 03 Apr 2025

Editorial: Crosstalk between metabolism and immunity

in Molecular Diagnostics and Therapeutics

Jie Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599219

1,359 views

Brief Research Report

Published on 03 Apr 2025

Determination of sample stability for a broad panel of coagulation parameters and factor assays on the Cobas t 711 analyzer starting from fresh-never-frozen plasma

in Molecular Diagnostics and Therapeutics

Michael Hoffmann
Norbert Gottschalk
Philipp Huber
Vanessa Scheling
Nicole von Allmen
J. Kolja Hegel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1491239

1,885 views

Original Research

Published on 02 Apr 2025

LT-YOLO: long-term temporal enhanced YOLO for stenosis detection on invasive coronary angiography

in Molecular Diagnostics and Therapeutics

Jiaxin Li
Xiang Tang
Xuesong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558495

2,274 views
2 citations

Correction

Published on 01 Apr 2025

Corrigendum: Comprehensive landscape of junctional genes and their association with overall survival of patients with lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Bin Xie
Ting Wu
Duiguo Hong
Zhe Lu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583736

803 views

Review

Published on 31 Mar 2025

The role of CAFs in therapeutic resistance in triple negative breast cancer: an emerging challenge

in Molecular Diagnostics and Therapeutics

Marianna Rita Brogna
Valeria Varone
Michele DelSesto
Gerardo Ferrara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1568865

5,941 views
7 citations

Original Research

Published on 31 Mar 2025

Establishment of a nomogram-based prognostic model (LASSO-Cox regression) for predicting platelet storage lesions under different storage conditions

in Molecular Diagnostics and Therapeutics

Jun Xiao
Huimin Li
Xiaowei Li
Huifen Lei
Zhicai Li
Cuiying Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561114

1,519 views

Systematic Review

Published on 26 Mar 2025

Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001–2024)

in Molecular Diagnostics and Therapeutics

Shuai Lu
Huaishuang Shen
Minjuan Li
Yiming Luo
Hao Sun
Xian Zhao
Jianming Chen
Ruifeng Bai
Pengli Han
Yejun Zha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1545109

3,110 views

Review

Published on 25 Mar 2025

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cells

in Molecular Diagnostics and Therapeutics

Meng Ning
Donghui Lu
Dong Liang
Pei-Gen Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1513993

5,665 views
2 citations

Original Research

Published on 25 Mar 2025

Role of Ca2+/calmodulin and PI3K/AKT signaling pathways and active ingredients of BaoTaiYin in treatment of recurrent miscarriage

in Molecular Diagnostics and Therapeutics

Li Ji
Anqi Deng
Huiying Chen
Shuangyan Guo
Pingyu Wang
Ruiyi Zhang
Wenyang Chen
Taotao Fan
Lijuan Jiang
Bing Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573294

3,645 views

Original Research

Published on 24 Mar 2025

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

in Molecular Diagnostics and Therapeutics

Gaurav Shoeran
Namrata Anand
Upninder Kaur
Kapil Goyal
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567703

1,612 views
1 citation

Original Research

Published on 21 Mar 2025

Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

in Molecular Diagnostics and Therapeutics

Wenjing Zhu
Zhengjie Zhang
Xinyuan Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552360

2,329 views
1 citation

Original Research

Published on 20 Mar 2025

Empowering limited-resource countries: collaborating with expert centers for diagnosis of primary ciliary dyskinesia

in Molecular Diagnostics and Therapeutics

Mine Yuksel Kalyoncu
Rim Hjeij
Muruvvet Yanaz
Aynur Gulieva
Merve Selcuk Balcı
Şeyda Karabulut
Neval Metin Cakar
Almala Pınar Ergenekon
Ela Erdem Eralp
Yasemin Gokdemir

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547152

1,996 views
1 citation

Original Research

Published on 19 Mar 2025

Comparison of two immunotoxins against DLL3 receptor; as an inhibitor for small cell lung cancer

in Molecular Diagnostics and Therapeutics

Mohammad Hossein Ataee
Seyed Ali Mirhosseini
Reza Mirnejad
Hamideh Mahmoodzadeh Hosseini
Jafar Amani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1506768

2,260 views

Review

Published on 19 Mar 2025

Effects of aging on calcium channels in skeletal muscle

in Molecular Diagnostics and Therapeutics

Mingyi Dong
Andrés Daniel Maturana

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558456

6,147 views

Original Research

Published on 19 Mar 2025

Osteoporotic vertebral fractures and subsequent fractures: risk factors from a retrospective observational study of patients with osteoporosis

in Molecular Diagnostics and Therapeutics

Mingxing Fan
Ran Lu
Jiayuan Wu
Jie Huang
Yanming Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558052

2,670 views
3 citations

Original Research

Published on 18 Mar 2025

Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target

in Molecular Diagnostics and Therapeutics

Fan Bu
Jifa Zhong
Ruiqian Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1506961

2,026 views
1 citation

Original Research

Published on 13 Mar 2025

Investigation of sphingolipid-related genes in lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Jibin Mao
Li Li
Hui Sun
Jie Han
Jinqiao Li
Chang-Sheng Dong
Hongyu Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548655

2,090 views
1 citation

Original Research

Published on 13 Mar 2025

Network pharmacology combined with untargeted metabolomics reveals the intervention mechanism and compatibility of chenpi-rougui herb pair in nonalcoholic fatty liver disease

in Molecular Diagnostics and Therapeutics

Jinlin Xu
Sen Li
Yuehui Jin
Huiwen Yao
Xu Hu
Shan Cao
Huimin Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1553162

3,881 views

Original Research

Published on 12 Mar 2025

Expression and distribution of activin-follistatin-inhibin axis in the urinary bladder

in Molecular Diagnostics and Therapeutics

Weipu Mao
Tracy Zhang
Huan Chen
Sagar Barge
Zongwei Wang
Aria Olumi
Seth Alper
Weiqun Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1519977

2,577 views

Original Research

Published on 12 Mar 2025

Integrative multi-omics analysis and machine learning refine global histone modification features in prostate cancer

in Molecular Diagnostics and Therapeutics

XiaoFeng He
QinTao Ge
WenYang Zhao
Chao Yu
HuiMing Bai
XiaoTong Wu
Jing Tao
WenHao Xu
Yunhua Qiu
Lei Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1557843

4,578 views
1 citation

Original Research

Published on 07 Mar 2025

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

in Molecular Diagnostics and Therapeutics

Qingrong Ma
Kai Chen
Haiping Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548810

2,810 views
3 citations

Brief Research Report

Published on 27 Feb 2025

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean area

in Molecular Diagnostics and Therapeutics

Maria Cristina Mazzarella
Stefano Cristiano
Dilia Rea
Nicola Mazzarella
Martina Addeo
Silvia Iannelli
Geppino Falco
Mariarita Brancaccio
Tiziana Angrisano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536953

2,260 views

Editorial

Published on 27 Feb 2025

Editorial: Role of fibroblast in cancer

in Molecular Diagnostics and Therapeutics

Xuezhen Zeng
Man Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1574538

1,491 views
1 citation

2,096 articles

articles

Integrated multi-omics analysis reveals the functional and prognostic significance of lactylation-related gene PRDX1 in breast cancer

Editorial: Crosstalk between metabolism and immunity

Determination of sample stability for a broad panel of coagulation parameters and factor assays on the Cobas t 711 analyzer starting from fresh-never-frozen plasma

LT-YOLO: long-term temporal enhanced YOLO for stenosis detection on invasive coronary angiography

Corrigendum: Comprehensive landscape of junctional genes and their association with overall survival of patients with lung adenocarcinoma

The role of CAFs in therapeutic resistance in triple negative breast cancer: an emerging challenge

Establishment of a nomogram-based prognostic model (LASSO-Cox regression) for predicting platelet storage lesions under different storage conditions

Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001–2024)

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cells

Role of Ca2+/calmodulin and PI3K/AKT signaling pathways and active ingredients of BaoTaiYin in treatment of recurrent miscarriage

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

Empowering limited-resource countries: collaborating with expert centers for diagnosis of primary ciliary dyskinesia

Comparison of two immunotoxins against DLL3 receptor; as an inhibitor for small cell lung cancer

Effects of aging on calcium channels in skeletal muscle

Osteoporotic vertebral fractures and subsequent fractures: risk factors from a retrospective observational study of patients with osteoporosis

Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target

Investigation of sphingolipid-related genes in lung adenocarcinoma

Network pharmacology combined with untargeted metabolomics reveals the intervention mechanism and compatibility of chenpi-rougui herb pair in nonalcoholic fatty liver disease

Expression and distribution of activin-follistatin-inhibin axis in the urinary bladder

Integrative multi-omics analysis and machine learning refine global histone modification features in prostate cancer

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean area

Editorial: Role of fibroblast in cancer