Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 02 Oct 2024

Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer

in Molecular Diagnostics and Therapeutics

Alessandro Rencinai
Eva Tollapi
Giulia Marianantoni
Jlenia Brunetti
Tania Henriquez
Alessandro Pini
Luisa Bracci
Chiara Falciani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429163

1,438 views
2 citations

Original Research

Published on 01 Oct 2024

Endoplasmic reticulum stress alters myelin associated protein expression and extracellular vesicle composition in human oligodendrocytes

in Molecular Diagnostics and Therapeutics

Ethan D. Evalt
Saranraj Govindaraj
Madison T. Jones
Nesve Ozsoy
Han Chen
Ashley E. Russell

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1432945

1,872 views
1 citation

Original Research

Published on 01 Oct 2024

Profiling genetic variants in cardiovascular disease genes among a Heterogeneous cohort of Mendelian conditions patients and electronic health records

in Molecular Diagnostics and Therapeutics

Nadia Akawi
Ghadeera Al Mansoori
Anwar Al Zaabi
Andrea Badics
Noura Al Dhaheri
Aisha Al Shamsi
Amal Al Tenaiji
Bashar Alzohily
Fatmah S. A. Almesmari
Hamad Al Hammadi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1451457

2,527 views

Editorial

Published on 30 Sep 2024

Editorial: Revisiting the challenges and opportunities in cancer drug resistance

in Molecular Diagnostics and Therapeutics

Tikam Chand Dakal
Narendra Kumar Sharma
Amit Sharma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1497754

1,209 views
1 citation

Original Research

Published on 30 Sep 2024

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

in Molecular Diagnostics and Therapeutics

Dmitry Kamashev
Nina Shaban
Galina Zakharova
Alexander Modestov
Мargarita Kamynina
Sergey Baranov
Anton Buzdin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1470496

1,723 views
1 citation

Original Research

Published on 27 Sep 2024

HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

in Molecular Diagnostics and Therapeutics

Polona Megušar
Ewen D. D. Calder
Tina Vodopivec Seravalli
Sergeja Lebar
Louise J. Walport
Rok Sekirnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1443917

2,713 views
1 citation

Original Research

Published on 23 Sep 2024

DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis

in Molecular Diagnostics and Therapeutics

Minglu Meng
Yingjiao Ma
Jianguo Xu
Gao Chen
Roshan Kumar Mahato

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1433557

1,121 views

Original Research

Published on 19 Sep 2024

Screening and identification of the hub genes in severe acute pancreatitis and sepsis

in Molecular Diagnostics and Therapeutics

Si-Jiu Yang
Yan Luo
Bao-He Chen
Ling-Hui Zhan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1425143

3,013 views
2 citations

Review

Published on 17 Sep 2024

Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges

in Molecular Diagnostics and Therapeutics

Philemon Ubanako
Sheefa Mirza
Paul Ruff
Clement Penny

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1447953

5,033 views
11 citations

Original Research

Published on 16 Sep 2024

The synergistic effects of anoikis-related genes and EMT-related genes in the prognostic prediction of Wilms tumor

in Molecular Diagnostics and Therapeutics

Kexin Meng
Zerui Zhao
Yaqing Gao
Keliang Wu
Wei Liu
Xiaoqing Wang
Yi Zheng
Wei Zhao
Bei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1469775

2,190 views

Original Research

Published on 13 Sep 2024

The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study

in Molecular Diagnostics and Therapeutics

Chao Song
Zhenkui Hu
Jinhui Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429372

1,457 views
1 citation

Original Research

Published on 13 Sep 2024

Identification and mechanistic analysis of neurovascular coupling related biomarkers for diabetic macular edema

in Molecular Diagnostics and Therapeutics

Tianpeng Chen
Shufan Sheng
Jing Chen
Xiaole Wang
Yanxing Shang
Chengwei Duan
Caixia Liang
Yu Song
Dongmei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1332842

1,735 views

Original Research

Published on 12 Sep 2024

Identification of ATRNL1 and WNT9A as novel key genes and drug candidates in hypertrophic cardiomyopathy: integrative bioinformatics and experimental validation

in Molecular Diagnostics and Therapeutics

Huabin He
Yanhui Liao
Yang Chen
Hao Qin
Longlong Hu
Shucai Xiao
Huijian Wang
Renqiang Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1458434

2,492 views
1 citation

Editorial

Published on 12 Sep 2024

Editorial: Lessons from external quality control in laboratory medicine: important implications for public health!

in Molecular Diagnostics and Therapeutics

Nathalie Weiss
Ingo Schellenberg
Klaus-Peter Hunfeld

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485193

1,080 views

Retraction

Published on 11 Sep 2024

Retraction: Identification of a novel ferroptosis inducer for gastric cancer treatment using drug repurposing strategy

in Molecular Diagnostics and Therapeutics

Frontiers Editorial Office

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1491755

881 views

Hypothesis and Theory

Published on 11 Sep 2024

Disease-related data patterns in cerebrospinal fluid diagnostics: medical quality versus analytical quantity

in Molecular Diagnostics and Therapeutics

Hansotto Reiber

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1348091

1,550 views