Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 19 Dec 2024

Development of 6-amido-4-aminoisoindolyn-1,3-diones as p70S6K1 inhibitors and potential breast cancer therapeutics

in Molecular Diagnostics and Therapeutics

Adrian Thornton
Rajesh Komati
Hogyoung Kim
Jamiah Myers
Kymmia Petty
Rion Sam
Elijah Johnson-Henderson
Keshunna Reese
Linh Tran
Vaniyambadi Sridhar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1481912

1,687 views

Original Research

Published on 11 Dec 2024

Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Li-Wei Zhang
Ji Yang
Hua-Wei Jiang
Xiu-Qiang Yang
Ya-Nan Chen
Wei-Dang Ying
Ying-Liang Deng
Min-hui Zhang
Hai Liu
Hong-Lei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524517

3,149 views
5 citations

Original Research

Published on 11 Dec 2024

Integrated multi-omics analysis describes immune profiles in ischemic heart failure and identifies PTN as a novel biomarker

in Molecular Diagnostics and Therapeutics

Ting Xiong
Quhuan Li
Yifan Wang
Ying Kong
Hailin Li
Jie Liu
Yueheng Wu
Fengxia Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524827

1,923 views

Original Research

Published on 09 Dec 2024

Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics

in Molecular Diagnostics and Therapeutics

Andong Guo
Chenrui Wu
Jishuang Cao
Kejia Zhu
Sentai Ding

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1521889

2,315 views

Review

Published on 09 Dec 2024

Development of anti-cancer drugs for tumor-associated macrophages: a comprehensive review and mechanistic insights

in Molecular Diagnostics and Therapeutics

Bingjun Bai
Shangzhi Xie
Ya Wang
Fei Wu
Yao Chen
Jia Bian
Xing Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1463061

2,896 views
4 citations

Original Research

Published on 06 Dec 2024

Identification of genetic associations between acute myocardial infarction and non-small cell lung cancer

in Molecular Diagnostics and Therapeutics

Hao Zheng
Jie Wang
Yijia Zheng
Xiaofan Hong
Luxi Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1502509

3,077 views
2 citations

Editorial

Published on 06 Dec 2024

Editorial: 14-3-3 proteins: possible importance in neurodegenerative diseases

in Molecular Diagnostics and Therapeutics

Dwijendra K. Gupta
Alan M. Tartakoff
Manish Dwivedi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1525126

3,098 views
1 citation

Original Research

Published on 05 Dec 2024

NUF2 is associated with cancer stem cell characteristics and a potential drug target for prostate cancer

in Molecular Diagnostics and Therapeutics

Dongxu Zhang
Pu Liang
Qi Wang
Bowen Xia
Liqian Yu
Xiaopeng Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1481375

3,809 views
4 citations

Original Research

Published on 04 Dec 2024

CircMIB1 inhibits glioma development and progression through a competing endogenous RNA interaction network

in Molecular Diagnostics and Therapeutics

Simin Chen
Longping Li
Wei Xu
Nanjiao Xie
Huiting Xu
Yongjun Zhou
Ying Zou
Kai Yi
Zuping Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1513919

2,001 views
1 citation

Editorial

Published on 04 Dec 2024

Editorial: LncRNA and their role on epigenome in cancer

in Molecular Diagnostics and Therapeutics

Qi Su
Francesca Maria Orlandella
Giovanni Smaldone
Yitao Qi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1533057

1,289 views

Original Research

Published on 03 Dec 2024

Investigation of the correlation between AGRN expression and perineural invasion in colon cancer

in Molecular Diagnostics and Therapeutics

Lei Chen
Haijia Zhang
Kaiyue Gao
Fanqi Meng
Funing Yang
Jiannan Li
Lijie Wang
Jiandong Tai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510478

3,242 views
1 citation

Review

Published on 27 Nov 2024

MMP9: Link between neuropathy and colorectal cancer?

in Molecular Diagnostics and Therapeutics

Cynthia Rosa Regalado
Mihály Balogh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1451611

4,591 views
7 citations

Original Research

Published on 25 Nov 2024

A novel necroptosis-related genes signature to predict prognosis and treatment response in bladder cancer

in Molecular Diagnostics and Therapeutics

Dongnuan Yao
Weitao Yu
Xueming Ma
Junqiang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1493411

2,643 views
2 citations

Review

Published on 22 Nov 2024

Precision-engineered PROTACs minimize off-tissue effects in cancer therapy

in Molecular Diagnostics and Therapeutics

Jianghua Shi
Luo Wang
Xuanwei Zeng
Chengzhi Xie
Zhaowei Meng
Anahit Campbell
Lulu Wang
Heli Fan
Huabing Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1505255

5,597 views
12 citations

Original Research

Published on 21 Nov 2024

Extended range proteomic analysis of blood plasma from schizophrenia patients

in Molecular Diagnostics and Therapeutics

Denis V. Petrovskiy
Tatiana V. Butkova
Kirill S. Nikolsky
Arthur T. Kopylov
Valeriya I. Nakhod
Liudmila I. Kulikova
Kristina A. Malsagova
Nikolai D. Kibrik
Vladimir R. Rudnev
Alexander A. Izotov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1483933

2,444 views

Review

Published on 21 Nov 2024

Bacteriophage RNA polymerases: catalysts for mRNA vaccines and therapeutics

in Molecular Diagnostics and Therapeutics

Adithya Nair
Zoltán Kis

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504876

6,905 views
7 citations

Brief Research Report

Published on 21 Nov 2024

Circulating GLAST+ EVs are increased in amyotrophic lateral sclerosis

in Molecular Diagnostics and Therapeutics

Davide Raineri
Fabiola De Marchi
Beatrice Vilardo
Camilla Barbero Mazzucca
Lorenza Scotti
Natasa Kustrimovic
Letizia Mazzini
Giuseppe Cappellano
Annalisa Chiocchetti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1507498

2,829 views
1 citation

Original Research

Published on 20 Nov 2024

Serum beta2-microglobulin and peripheral blood eosinophils for the assessment of severity and prognosis with omicron variant COVID-19 infection

in Molecular Diagnostics and Therapeutics

Jie Tan
Hanxi Fang
Xiao Hu
Ming Yue
Junling Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1476080

1,675 views
1 citation

Original Research

Published on 20 Nov 2024

Identification of key genes to predict response to chemoradiotherapy and prognosis in esophageal squamous cell carcinoma

in Molecular Diagnostics and Therapeutics

Yingying Cui
Jing Wen
Jianhua Fu
Changsen Leng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1512715

2,411 views
1 citation

Editorial

Published on 13 Nov 2024

Editorial: Machine learning approaches for differential diagnosis, prognosis, prevention, and treatment of digestive system disorders

in Molecular Diagnostics and Therapeutics

Xinyan Wu
Xiaomei Zheng
Gang Ye

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1521170

1,128 views

Review

Published on 12 Nov 2024

Esophageal adenocarcinoma models: a closer look

in Molecular Diagnostics and Therapeutics

Nadeem Bhat
Marwah Al-Mathkour
Selma Maacha
Heng Lu
Wael El-Rifai
Farah Ballout

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1440670

3,469 views
2 citations

Original Research

Published on 11 Nov 2024

Proteomics analysis of extracellular vesicles for biomarkers of autism spectrum disorder

in Molecular Diagnostics and Therapeutics

Houda Yasmine Ali Moussa
Kyung Chul Shin
Alberto de la Fuente
Ilham Bensmail
Houari B. Abdesselem
Janarthanan Ponraj
Said Mansour
Fouad A. Al-Shaban
Lawrence W. Stanton
Sara A. Abdulla

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1467398

4,163 views
4 citations

Original Research

Published on 01 Nov 2024

Differential expression of ferroptosis-related proteins in urinary exosomes: potential indicators for monitoring acute gout attack

in Molecular Diagnostics and Therapeutics

Jitu Wang
Yubin Lin
Na Liu
Mei Hu
Man Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1476631

2,495 views
2 citations

Original Research

Published on 30 Oct 2024

Development of a prognostic model for early-stage gastric cancer-related DNA methylation-driven genes and analysis of immune landscape

in Molecular Diagnostics and Therapeutics

Chen Su
Zeyang Lin
Zhijian Ye
Jing Liang
Rong Yu
Zheng Wan
Jingjing Hou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1455890

2,356 views
4 citations

2,096 articles

articles

Development of 6-amido-4-aminoisoindolyn-1,3-diones as p70S6K1 inhibitors and potential breast cancer therapeutics

Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning

Integrated multi-omics analysis describes immune profiles in ischemic heart failure and identifies PTN as a novel biomarker

Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics

Development of anti-cancer drugs for tumor-associated macrophages: a comprehensive review and mechanistic insights

Identification of genetic associations between acute myocardial infarction and non-small cell lung cancer

Editorial: 14-3-3 proteins: possible importance in neurodegenerative diseases

NUF2 is associated with cancer stem cell characteristics and a potential drug target for prostate cancer

CircMIB1 inhibits glioma development and progression through a competing endogenous RNA interaction network

Editorial: LncRNA and their role on epigenome in cancer

Investigation of the correlation between AGRN expression and perineural invasion in colon cancer

MMP9: Link between neuropathy and colorectal cancer?

A novel necroptosis-related genes signature to predict prognosis and treatment response in bladder cancer

Precision-engineered PROTACs minimize off-tissue effects in cancer therapy

Extended range proteomic analysis of blood plasma from schizophrenia patients

Bacteriophage RNA polymerases: catalysts for mRNA vaccines and therapeutics

Circulating GLAST+ EVs are increased in amyotrophic lateral sclerosis

Serum beta2-microglobulin and peripheral blood eosinophils for the assessment of severity and prognosis with omicron variant COVID-19 infection

Identification of key genes to predict response to chemoradiotherapy and prognosis in esophageal squamous cell carcinoma

Editorial: Machine learning approaches for differential diagnosis, prognosis, prevention, and treatment of digestive system disorders

Esophageal adenocarcinoma models: a closer look

Proteomics analysis of extracellular vesicles for biomarkers of autism spectrum disorder

Differential expression of ferroptosis-related proteins in urinary exosomes: potential indicators for monitoring acute gout attack

Development of a prognostic model for early-stage gastric cancer-related DNA methylation-driven genes and analysis of immune landscape