Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 30 Oct 2024

Development of a prognostic model for early-stage gastric cancer-related DNA methylation-driven genes and analysis of immune landscape

in Molecular Diagnostics and Therapeutics

Chen Su
Zeyang Lin
Zhijian Ye
Jing Liang
Rong Yu
Zheng Wan
Jingjing Hou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1455890

2,356 views
4 citations

Correction

Published on 28 Oct 2024

Corrigendum: Cellular heterogeneity and plasticity during NAFLD progression

in Molecular Diagnostics and Therapeutics

Hyun-Ju Park
Juyong Choi
Hyunmi Kim
Da-Yeon Yang
Tae Hyeon An
Eun-Woo Lee
Baek-Soo Han
Sang Chul Lee
Won Kon Kim
Kwang-Hee Bae

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1511947

1,305 views

Original Research

Published on 24 Oct 2024

Novel cuproptosis metabolism-related molecular clusters and diagnostic signature for Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Fang Jia
Wanhong Han
Shuangqi Gao
Jianwei Huang
Wujie Zhao
Zhenwei Lu
Wenpeng Zhao
Zhangyu Li
Zhanxiang Wang
Ying Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1478611

5,055 views
3 citations

Original Research

Published on 23 Oct 2024

Prognosis prediction of head and neck squamous cell carcinoma through the basement membrane-related lncRNA risk model

in Molecular Diagnostics and Therapeutics

Wenchao Bu
Mingguo Cao
Xinru Wu
Qiancheng Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1421335

3,015 views
1 citation

Correction

Published on 22 Oct 2024

Corrigendum: HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

in Molecular Diagnostics and Therapeutics

Polona Megušar
Ewen D. D. Calder
Tina Vodopivec Seravalli
Sergeja Lebar
Louise J. Walport
Rok Sekirnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1507191

1,173 views

Original Research

Published on 16 Oct 2024

Integrating molecular, biochemical, and immunohistochemical features as predictors of hepatocellular carcinoma drug response using machine-learning algorithms

in Molecular Diagnostics and Therapeutics

Marwa Matboli
Hiba S. Al-Amodi
Abdelrahman Khaled
Radwa Khaled
Marwa Ali
Hala F. M. Kamel
Manal S. Abd EL Hamid
Hind A. ELsawi
Eman K. Habib
Ibrahim Youssef

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1430794

3,300 views

Original Research

Published on 15 Oct 2024

Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor

in Molecular Diagnostics and Therapeutics

Fatma S. Mohamed
Deena Jalal
Youssef M. Fadel
Samir F. El-Mashtoly
Wael Z. Khaled
Ahmed A. Sayed
Mohamed A. Ghazy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1453562

2,749 views
2 citations

Review

Published on 11 Oct 2024

How lactate affects immune strategies in lymphoma

in Molecular Diagnostics and Therapeutics

Yuehan Zhou
Jinzhan Lou
Yuqin Tian
Jinlei Ding
Xiaobo Wang
Bo Tang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1480884

3,751 views
5 citations

Correction

Published on 08 Oct 2024

Corrigendum: Comprehensive analysis of the prognostic and immunological role of PAFAH1B in pan-cancer

in Molecular Diagnostics and Therapeutics

Yixiao Yuan
Xiulin Jiang
Lin Tang
Juan Wang
Lincan Duan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1497296

1,198 views

Original Research

Published on 03 Oct 2024

Investigating the effects of combined treatment of mesalazine with Lactobacillus casei in the experimental model of ulcerative colitis

in Molecular Diagnostics and Therapeutics

Shabnam Bahrami
Nahid Babaei
Hadi Esmaeili Gouvarchin Ghaleh
Jaleh Mohajeri Borazjani
Mahdieh Farzanehpour

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1456053

4,145 views
3 citations

Original Research

Published on 02 Oct 2024

Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer

in Molecular Diagnostics and Therapeutics

Alessandro Rencinai
Eva Tollapi
Giulia Marianantoni
Jlenia Brunetti
Tania Henriquez
Alessandro Pini
Luisa Bracci
Chiara Falciani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429163

2,193 views
2 citations

Original Research

Published on 01 Oct 2024

Endoplasmic reticulum stress alters myelin associated protein expression and extracellular vesicle composition in human oligodendrocytes

in Molecular Diagnostics and Therapeutics

Ethan D. Evalt
Saranraj Govindaraj
Madison T. Jones
Nesve Ozsoy
Han Chen
Ashley E. Russell

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1432945

2,831 views
2 citations

Original Research

Published on 01 Oct 2024

Profiling genetic variants in cardiovascular disease genes among a Heterogeneous cohort of Mendelian conditions patients and electronic health records

in Molecular Diagnostics and Therapeutics

Nadia Akawi
Ghadeera Al Mansoori
Anwar Al Zaabi
Andrea Badics
Noura Al Dhaheri
Aisha Al Shamsi
Amal Al Tenaiji
Bashar Alzohily
Fatmah S. A. Almesmari
Hamad Al Hammadi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1451457

4,520 views

Editorial

Published on 30 Sep 2024

Editorial: Revisiting the challenges and opportunities in cancer drug resistance

in Molecular Diagnostics and Therapeutics

Tikam Chand Dakal
Narendra Kumar Sharma
Amit Sharma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1497754

2,016 views
3 citations

Original Research

Published on 30 Sep 2024

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

in Molecular Diagnostics and Therapeutics

Dmitry Kamashev
Nina Shaban
Galina Zakharova
Alexander Modestov
Мargarita Kamynina
Sergey Baranov
Anton Buzdin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1470496

2,653 views
2 citations

Original Research

Published on 27 Sep 2024

HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

in Molecular Diagnostics and Therapeutics

Polona Megušar
Ewen D. D. Calder
Tina Vodopivec Seravalli
Sergeja Lebar
Louise J. Walport
Rok Sekirnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1443917

4,397 views
3 citations

Original Research

Published on 23 Sep 2024

DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis

in Molecular Diagnostics and Therapeutics

Minglu Meng
Yingjiao Ma
Jianguo Xu
Gao Chen
Roshan Kumar Mahato

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1433557

1,875 views
1 citation

Original Research

Published on 19 Sep 2024

Screening and identification of the hub genes in severe acute pancreatitis and sepsis

in Molecular Diagnostics and Therapeutics

Si-Jiu Yang
Yan Luo
Bao-He Chen
Ling-Hui Zhan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1425143

4,416 views
3 citations

Review

Published on 17 Sep 2024

Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges

in Molecular Diagnostics and Therapeutics

Philemon Ubanako
Sheefa Mirza
Paul Ruff
Clement Penny

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1447953

8,886 views
34 citations

Original Research

Published on 16 Sep 2024

The synergistic effects of anoikis-related genes and EMT-related genes in the prognostic prediction of Wilms tumor

in Molecular Diagnostics and Therapeutics

Kexin Meng
Zerui Zhao
Yaqing Gao
Keliang Wu
Wei Liu
Xiaoqing Wang
Yi Zheng
Wei Zhao
Bei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1469775

2,926 views
2 citations

Original Research

Published on 13 Sep 2024

The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study

in Molecular Diagnostics and Therapeutics

Chao Song
Zhenkui Hu
Jinhui Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429372

2,714 views
6 citations

Original Research

Published on 13 Sep 2024

Identification and mechanistic analysis of neurovascular coupling related biomarkers for diabetic macular edema

in Molecular Diagnostics and Therapeutics

Tianpeng Chen
Shufan Sheng
Jing Chen
Xiaole Wang
Yanxing Shang
Chengwei Duan
Caixia Liang
Yu Song
Dongmei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1332842

2,611 views
1 citation

Original Research

Published on 12 Sep 2024

Identification of ATRNL1 and WNT9A as novel key genes and drug candidates in hypertrophic cardiomyopathy: integrative bioinformatics and experimental validation

in Molecular Diagnostics and Therapeutics

Huabin He
Yanhui Liao
Yang Chen
Hao Qin
Longlong Hu
Shucai Xiao
Huijian Wang
Renqiang Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1458434

3,570 views
2 citations

Editorial

Published on 12 Sep 2024

Editorial: Lessons from external quality control in laboratory medicine: important implications for public health!

in Molecular Diagnostics and Therapeutics

Nathalie Weiss
Ingo Schellenberg
Klaus-Peter Hunfeld

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485193

1,776 views
1 citation

2,097 articles

articles

Development of a prognostic model for early-stage gastric cancer-related DNA methylation-driven genes and analysis of immune landscape

Corrigendum: Cellular heterogeneity and plasticity during NAFLD progression

Novel cuproptosis metabolism-related molecular clusters and diagnostic signature for Alzheimer’s disease

Prognosis prediction of head and neck squamous cell carcinoma through the basement membrane-related lncRNA risk model

Corrigendum: HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

Integrating molecular, biochemical, and immunohistochemical features as predictors of hepatocellular carcinoma drug response using machine-learning algorithms

Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor

How lactate affects immune strategies in lymphoma

Corrigendum: Comprehensive analysis of the prognostic and immunological role of PAFAH1B in pan-cancer

Investigating the effects of combined treatment of mesalazine with Lactobacillus casei in the experimental model of ulcerative colitis

Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer

Endoplasmic reticulum stress alters myelin associated protein expression and extracellular vesicle composition in human oligodendrocytes

Profiling genetic variants in cardiovascular disease genes among a Heterogeneous cohort of Mendelian conditions patients and electronic health records

Editorial: Revisiting the challenges and opportunities in cancer drug resistance

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis

Screening and identification of the hub genes in severe acute pancreatitis and sepsis

Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges

The synergistic effects of anoikis-related genes and EMT-related genes in the prognostic prediction of Wilms tumor

The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study

Identification and mechanistic analysis of neurovascular coupling related biomarkers for diabetic macular edema

Identification of ATRNL1 and WNT9A as novel key genes and drug candidates in hypertrophic cardiomyopathy: integrative bioinformatics and experimental validation

Editorial: Lessons from external quality control in laboratory medicine: important implications for public health!