Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 17 Apr 2024

Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

in Molecular Diagnostics and Therapeutics

Yanting Chen
Xiaohan Lu
Raeann L. Whitney
Yu Li
Matthew J. Robson
Randy D. Blakely
Jen-Tsan Chi
Steven D. Crowley
Jamie R. Privratsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1366259

4,443 views
6 citations

Original Research

Published on 17 Apr 2024

Gasdermin B (GSDMB) in psoriatic patients–a preliminary comprehensive study on human serum, urine and skin

in Molecular Diagnostics and Therapeutics

Julia Nowowiejska
Anna Baran
Anna Pryczynicz
Justyna Magdalena Hermanowicz
Beata Sieklucka
Dariusz Pawlak
Iwona Flisiak

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1382069

2,443 views
4 citations

Review

Published on 16 Apr 2024

Current strategies for early epithelial ovarian cancer detection using miRNA as a potential tool

in Molecular Diagnostics and Therapeutics

Mridula Bhadra
Manisha Sachan
Seema Nara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1361601

4,520 views
9 citations

Review

Published on 16 Apr 2024

Mesenchymal stem cells in craniofacial reconstruction: a comprehensive review

in Molecular Diagnostics and Therapeutics

Zizhuo Zheng
Hanghang Liu
Shibo Liu
En Luo
Xian Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1362338

4,857 views
10 citations

Original Research

Published on 10 Apr 2024

Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set

in Molecular Diagnostics and Therapeutics

Xuefeng Gu
Zhongxian Yu
Tianwei Qian
Yiqi Jin
Guoxiong Xu
Jiang Li
Jianfeng Gu
Ming Li
Ke Tao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1365447

4,047 views
3 citations

Review

Published on 04 Apr 2024

Schwann cells in the normal and pathological lung microenvironment

in Molecular Diagnostics and Therapeutics

Michael R. Shurin
Sarah E. Wheeler
Galina V. Shurin
Hua Zhong
Yan Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1365760

5,308 views
9 citations

Original Research

Published on 04 Apr 2024

An IL-17A-centric response to Epstein-Barr virus DNA mediated by dendritic Cell-T cell interactions

in Molecular Diagnostics and Therapeutics

Marwa Shehab
Hadi Hussein
Sukayna Fadlallah
Elias A. Rahal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1243366

2,189 views
1 citation

Original Research

Published on 04 Apr 2024

Characterization of four peptides from milk fermented with kombucha cultures and their metal complexes—in search of new biotherapeutics

in Molecular Diagnostics and Therapeutics

Justyna Kamińska
Aleksandra Hecel
Joanna Słowik
Agnieszka Rombel-Bryzek
Magdalena Rowińska-Żyrek
Danuta Witkowska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1366588

2,639 views
4 citations

Original Research

Published on 03 Apr 2024

SIRT1/P53 in retinal pigment epithelial cells in diabetic retinopathy: a gene co-expression analysis and He-Ying-Qing-Re formula treatment

in Molecular Diagnostics and Therapeutics

Shuyan Zhang
Jiajun Wu
Leilei Wang
Lin Mu
Xiaoyu Xu
Jiahui Li
Guoyi Tang
Guang Chen
Cheng Zhang
Yinjian Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1366020

4,005 views
10 citations

Original Research

Published on 03 Apr 2024

TGF-β mRNA levels in circulating extracellular vesicles are associated with response to anti-PD1 treatment in metastatic melanoma

in Molecular Diagnostics and Therapeutics

Stefania Crucitta
Federico Cucchiara
Riccardo Marconcini
Alessandra Bulleri
Simona Manacorda
Annalisa Capuano
Dania Cioni
Amedeo Nuzzo
Evert de Jonge
Ron H. J. Mathjissen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1288677

2,527 views
2 citations

Original Research

Published on 28 Mar 2024

Effects of saponins Rb1 and Re in American ginseng combined intervention on immune system of aging model

in Molecular Diagnostics and Therapeutics

Mao Shi
Jie Ma
Shan Jin
Tienan Wang
Yuhan Sui
Lina Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1392868

3,738 views
8 citations

Original Research

Published on 28 Mar 2024

GEO dataset mining analysis reveals novel Staphylococcus aureus virulence gene regulatory networks and diagnostic targets in mice

in Molecular Diagnostics and Therapeutics

Guangyu Xu
Yue Yang
Yan Lin
Yu Bai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1381334

2,967 views

Original Research

Published on 27 Mar 2024

Longitudinal analysis of 20 Years of external quality assurance schemes for PCR/NAAT-based bacterial genome detection in diagnostic testing

in Molecular Diagnostics and Therapeutics

Marcel Kremser
Nathalie Weiss
Anne Kaufmann-Stoeck
Laura Vierbaum
Silke Kappler
Ingo Schellenberg
Andreas Hiergeist
Volker Fingerle
Michael Baier
Udo Reischl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1373114

2,598 views

Review

Published on 26 Mar 2024

Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma

in Molecular Diagnostics and Therapeutics

Ming Zeng
Can Liu
Haoli Gong
Zhongwen Tang
Jie Wen
Sisi Wang
Sheng Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1367331

3,470 views
6 citations

Editorial

Published on 25 Mar 2024

Editorial: Advanced functional nanomaterials for diagnosis, bioimaging, drug delivery and therapeutics

in Molecular Diagnostics and Therapeutics

Eudald Casals
Shunbo Li
Zhiyu Jia
Gregori Casals
Muling Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1399695

1,618 views
1 citation

Original Research

Published on 22 Mar 2024

Prostate fibroblasts and prostate cancer associated fibroblasts exhibit different metabolic, matrix degradation and PD-L1 expression responses to hypoxia

in Molecular Diagnostics and Therapeutics

Jesus Pacheco-Torres
Raj Kumar Sharma
Yelena Mironchik
Flonne Wildes
W. Nathaniel Brennen
Dmitri Artemov
Balaji Krishnamachary
Zaver M. Bhujwalla

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1354076

3,554 views
2 citations

Original Research

Published on 22 Mar 2024

Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation

in Molecular Diagnostics and Therapeutics

Yueqing Gong
Yaxin Lou
Xiurui Han
Keyan Chen
Yang Zhao
Hejun Zhang
Jing Zhang
Ying Xiong
Weiwei Fu
Shigang Ding

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1252058

4,014 views
4 citations

Original Research

Published on 20 Mar 2024

Quality assessment of glucose measurement with regard to epidemiology and clinical management of diabetes mellitus in Germany

in Molecular Diagnostics and Therapeutics

Peter B. Luppa
Michael Zeller
Marija Pieper
Patricia Kaiser
Nathalie Weiss
Laura Vierbaum
Guido Freckmann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1371426

3,128 views
1 citation

Original Research

Published on 19 Mar 2024

Deep learning-based identification of esophageal cancer subtypes through analysis of high-resolution histopathology images

in Molecular Diagnostics and Therapeutics

Syed Wajid Aalam
Abdul Basit Ahanger
Tariq A. Masoodi
Ajaz A. Bhat
Ammira S. Al-Shabeeb Akil
Meraj Alam Khan
Assif Assad
Muzafar A. Macha
Muzafar Rasool Bhat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1346242

5,809 views
9 citations

Review

Published on 18 Mar 2024

Cancer-associated fibroblasts: protagonists of the tumor microenvironment in gastric cancer

in Molecular Diagnostics and Therapeutics

Ece Ozmen
Tevriz Dilan Demir
Gulnihal Ozcan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1340124

10,171 views
30 citations

Editorial

Published on 13 Mar 2024

Editorial: Medical big data in cancer research

in Molecular Diagnostics and Therapeutics

Jingxin Mao
Ke Zheng
Xiong Weng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1395607

1,941 views
2 citations

Original Research

Published on 13 Mar 2024

An in vitro analysis of an innovative standardized phospholipid carrier-based Melissa officinalis L. extract as a potential neuromodulator for emotional distress and related conditions

in Molecular Diagnostics and Therapeutics

Mehtap Kara
Sumeyye Sahin
Fazle Rabbani
Ezgi Oztas
Gozde Hasbal-Celikok
Ebru Kanımdan
Abdurrahim Kocyigit
Ayesha Kanwal
Ursula Wade
Anastasia Yakunina

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1359177

4,993 views
6 citations

Editorial

Published on 12 Mar 2024

Editorial: AI and multi-omics for rare diseases: challenges, advances and perspectives, Volume III

in Molecular Diagnostics and Therapeutics

Frank Emmert-Streib
Silvia Bottini
Leonardo Franco

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1392943

2,196 views

Review

Published on 08 Mar 2024

Illumination of understudied ciliary kinases

in Molecular Diagnostics and Therapeutics

Raymond G. Flax
Peter Rosston
Cecilia Rocha
Brian Anderson
Jacob L. Capener
Thomas M. Durcan
David H. Drewry
Panagiotis Prinos
Alison D. Axtman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1352781

5,136 views
6 citations

2,097 articles

articles

Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI

Gasdermin B (GSDMB) in psoriatic patients–a preliminary comprehensive study on human serum, urine and skin

Current strategies for early epithelial ovarian cancer detection using miRNA as a potential tool

Mesenchymal stem cells in craniofacial reconstruction: a comprehensive review

Transcriptomic analysis identifies the shared diagnostic biomarkers and immune relationship between Atherosclerosis and abdominal aortic aneurysm based on fatty acid metabolism gene set

Schwann cells in the normal and pathological lung microenvironment

An IL-17A-centric response to Epstein-Barr virus DNA mediated by dendritic Cell-T cell interactions

Characterization of four peptides from milk fermented with kombucha cultures and their metal complexes—in search of new biotherapeutics

SIRT1/P53 in retinal pigment epithelial cells in diabetic retinopathy: a gene co-expression analysis and He-Ying-Qing-Re formula treatment

TGF-β mRNA levels in circulating extracellular vesicles are associated with response to anti-PD1 treatment in metastatic melanoma

Effects of saponins Rb1 and Re in American ginseng combined intervention on immune system of aging model

GEO dataset mining analysis reveals novel Staphylococcus aureus virulence gene regulatory networks and diagnostic targets in mice

Longitudinal analysis of 20 Years of external quality assurance schemes for PCR/NAAT-based bacterial genome detection in diagnostic testing

Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma

Editorial: Advanced functional nanomaterials for diagnosis, bioimaging, drug delivery and therapeutics

Prostate fibroblasts and prostate cancer associated fibroblasts exhibit different metabolic, matrix degradation and PD-L1 expression responses to hypoxia

Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation

Quality assessment of glucose measurement with regard to epidemiology and clinical management of diabetes mellitus in Germany

Deep learning-based identification of esophageal cancer subtypes through analysis of high-resolution histopathology images

Cancer-associated fibroblasts: protagonists of the tumor microenvironment in gastric cancer

Editorial: Medical big data in cancer research

An in vitro analysis of an innovative standardized phospholipid carrier-based Melissa officinalis L. extract as a potential neuromodulator for emotional distress and related conditions

Editorial: AI and multi-omics for rare diseases: challenges, advances and perspectives, Volume III

Illumination of understudied ciliary kinases