Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Brief Research Report

Published on 22 Jan 2025

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression

in Molecular Diagnostics and Therapeutics

Shankar Suman
Wendy K. Nevala
Alexey A. Leontovich
James W. Jakub
Liyi Geng
Sarah A. McLaughlin
Svetomir N. Markovic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1522717

250 views

Original Research

Published on 22 Jan 2025

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

in Molecular Diagnostics and Therapeutics

Xiao Du
Hongxiu Li
Shiyi Shen
Chao Tian
Xiaohuan Cao
Xingang Xu
Nan Xu
Shuling Wang
Qingchang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531108

208 views

Editorial

Published on 21 Jan 2025

Editorial: Oncolytic virotherapy, volume II

in Molecular Diagnostics and Therapeutics

Ahmed Majeed Al-Shammari
Pier Paolo Piccaluga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552643

444 views

Original Research

Published on 21 Jan 2025

Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples

in Molecular Diagnostics and Therapeutics

Maxim Sorokin
Vladimir Lyadov
Maria Suntsova
Marat Garipov
Anna Semenova
Natalia Popova
Egor Guguchkin
Rustam Heydarov
Marianna Zolotovskaia
Xiaowen Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1448792

252 views

Original Research

Accepted on 20 Jan 2025

Defining the High-Risk Category of Patients with Cutaneous Melanoma: a Practical Tool Based on Prognostic Modeling

in Molecular Diagnostics and Therapeutics

Oleksandr Dudin
Ozar Mintser
Vitaly Gurianov
Nazarii Kobyliak
Denys Kozakov
Sofiia Livshun
Oksana Sulaieva

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1543148

Original Research

Accepted on 20 Jan 2025

An unfolded protein response (UPR)-signature regulated by NFKB-miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer

in Molecular Diagnostics and Therapeutics

Jian Zhang
Xiaosong Fan
Yu Chen
Yichao Han
Weixing Yu
Shaolin Zhang
Bicheng Yang
Junlong Zhang
Yanling Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542650

Original Research

Accepted on 20 Jan 2025

Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Jianhui Chen
Qun Li
Xiaofang Liu
Fang Lin
Yaling Jing
Jiayan Yang
Lianfang Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1529507

Original Research

Accepted on 17 Jan 2025

Establishment and Validation of a Recurrent Prediction Model for Glioma: Extrinsic Apoptotic Molecules FADD and CASP8 Are Closely Associated With Glioma Recurrence

in Molecular Diagnostics and Therapeutics

Lei Yang
Li Lanying
YanFang Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1533370

Original Research

Published on 17 Jan 2025

Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Wanru Zhou
Lijun Wang
Wei Lou
Yao Zhang
Haiying Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538743

182 views

Original Research

Published on 17 Jan 2025

Plasma proteome fingerprint in kidney diseases

in Molecular Diagnostics and Therapeutics

Kirill S. Nikolsky
Arthur T. Kopylov
Valeriya I. Nakhod
Natalia V. Potoldykova
Dmitry V. Enikeev
Tatiana V. Butkova
Liudmila I. Kulikova
Kristina A. Malsagova
Vladimir R. Rudnev
Denis V. Petrovskiy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1494779

377 views

Review

Accepted on 15 Jan 2025

The role of potential oxidative biomarkers in the Prognosis of Intracerebral Hemorrhage and the exploration antioxidants as possible Preventive and Treatment options

in Molecular Diagnostics and Therapeutics

Jiayong Yao
xiaohong dai
xueping yv
lei zheng
jia zheng
binglin kuang
wei teng
weiwei yu
mignyue li
hongtao cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1541230

Review

Accepted on 15 Jan 2025

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

in Molecular Diagnostics and Therapeutics

Xiaosi Gu
Xin Hu
Sijia Zhang
Xiaoyu Zhang
Yong Wang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1540048

Original Research

Published on 15 Jan 2025

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

in Molecular Diagnostics and Therapeutics

Alexandra Razumovskaya
Mariia Silkina
Andrey Poloznikov
Timur Kulagin
Maria Raigorodskaya
Nina Gorban
Anna Kudryavtseva
Maria Fedorova
Boris Alekseev
Alexander Tonevitsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531175

442 views

Original Research

Accepted on 13 Jan 2025

Deciphering the Role of miRNA-mRNA Interactions in Cerebral Vasospasm Post Intracranial Hemorrhage

in Molecular Diagnostics and Therapeutics

Xiang Chu
Xiyan Zhu
Honghao Xu
Wenbing Zhao
Debin Guo
Xing Chen
Jinze Wu
Lei Li
Hao Wang
Jun Fei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1492729

Original Research

Accepted on 09 Jan 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

151 views

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

454 views

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Articles

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

Editorial: Oncolytic virotherapy, volume II

Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples

Defining the High-Risk Category of Patients with Cutaneous Melanoma: a Practical Tool Based on Prognostic Modeling

An unfolded protein response (UPR)-signature regulated by NFKB-miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer

Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning

Establishment and Validation of a Recurrent Prediction Model for Glioma: Extrinsic Apoptotic Molecules FADD and CASP8 Are Closely Associated With Glioma Recurrence

Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis

Plasma proteome fingerprint in kidney diseases

The role of potential oxidative biomarkers in the Prognosis of Intracerebral Hemorrhage and the exploration antioxidants as possible Preventive and Treatment options

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

Deciphering the Role of miRNA-mRNA Interactions in Cerebral Vasospasm Post Intracranial Hemorrhage

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis