Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 08 Mar 2024

The C-terminal selenenylsulfide of extracellular/non-reduced thioredoxin reductase endows this protein with selectivity to small-molecule electrophilic reagents under oxidative conditions

in Molecular Diagnostics and Therapeutics

Huijun Qin
Chenchen Guo
Bozhen Chen
Hui Huang
Yaping Tian
Liangwei Zhong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1274850

2,754 views
1 citation

Editorial

Published on 07 Mar 2024

Editorial: New progress in cancer biomarkers and therapy

in Molecular Diagnostics and Therapeutics

Guohui Sun
Chengwei He
Jianhua Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1388872

2,651 views

Original Research

Published on 07 Mar 2024

Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development

in Molecular Diagnostics and Therapeutics

Emma N. Welbourne
Kate A. Loveday
Adithya Nair
Ehsan Nourafkan
Jixin Qu
Ken Cook
Zoltán Kis
Mark J. Dickman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1250833

13,336 views
16 citations

Original Research

Published on 29 Feb 2024

Serum ferritin and neutrophil-to-lymphocyte ratio predict all-cause mortality in patients receiving maintenance hemodialysis: a prospective study

in Molecular Diagnostics and Therapeutics

Jiamin He
Changyan Li
Jie Ge
Zhen Li
Lingyan Cao
Wenxing Fan
Yunzhu Peng
Qiongfang Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1366753

3,664 views
4 citations

Original Research

Published on 22 Feb 2024

Circulating serum miR-362-3p and miR-6721-5p as potential biomarkers for classification patients with adult-type diffuse glioma

in Molecular Diagnostics and Therapeutics

Magdalena Niemira
Agnieszka Bielska
Karolina Chwialkowska
Justyna Raczkowska
Anna Skwarska
Anna Erol
Anna Zeller
Gabriela Sokolowska
Damian Toczydlowski
Iwona Sidorkiewicz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1368372

3,157 views
6 citations

Review

Published on 22 Feb 2024

Tumor cell stemness in gastrointestinal cancer: regulation and targeted therapy

in Molecular Diagnostics and Therapeutics

Kangqi Yang
Tuo Yi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1297611

3,318 views
2 citations

Editorial

Published on 22 Feb 2024

Editorial: Bioengineered nanoparticles in cancer therapy, Volume III

in Molecular Diagnostics and Therapeutics

Tomy J. Gutiérrez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1356081

1,216 views
2 citations

Review

Published on 22 Feb 2024

Dynamic interactions in the tumor niche: how the cross-talk between CAFs and the tumor microenvironment impacts resistance to therapy

in Molecular Diagnostics and Therapeutics

Oliwia Piwocka
Igor Piotrowski
Wiktoria M. Suchorska
Katarzyna Kulcenty

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1343523

7,585 views
39 citations

Mini Review

Published on 21 Feb 2024

Harnessing microRNA-enriched extracellular vesicles for liquid biopsy

in Molecular Diagnostics and Therapeutics

Song Yi Ko
WonJae Lee
Honami Naora

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1356780

3,401 views
11 citations

Original Research

Published on 21 Feb 2024

Gene expression in metastatic breast cancer—patterns in primary tumors and metastatic tissue with prognostic potential

in Molecular Diagnostics and Therapeutics

Julia Tutzauer
Anna-Maria Larsson
Kristina Aaltonen
Caroline Bergenfelz
Pär-Ola Bendahl
Lisa Rydén

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1343979

4,063 views
4 citations

Original Research

Published on 15 Feb 2024

Extracellular vesicles in the treatment of oxidative stress injury: global research status and trends

in Molecular Diagnostics and Therapeutics

Wenwen Zhang
Bin Gan
Tingyu Wang
Xiangjie Yang
Yuanye Xue
Yuanqing Zhong
Xintong He
Xinsheng Peng
Yanfang Zhou
Xiaoyan Cheng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1273113

4,492 views
2 citations

Original Research

Published on 09 Feb 2024

Analytical validation and clinical utilization of K-4CARE™: a comprehensive genomic profiling assay with personalized MRD detection

in Molecular Diagnostics and Therapeutics

Thien-Phuc Nguyen Hoang
Tien Anh Nguyen
Nam H. B. Tran
Van-Anh Nguyen Hoang
Hong Thuy Thi Dao
Vu-Uyen Tran
Yen Nhi Nguyen
Anh Tuan Nguyen
Cam Tu Nguyen Thi
Thanh Thuy Do Thi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1334808

4,913 views
6 citations

Brief Research Report

Published on 06 Feb 2024

The potential of N2-modified cap analogues for precise genetic manipulation through mRNA engineering

in Molecular Diagnostics and Therapeutics

Karol Kurpiejewski
Anna Stankiewicz-Drogon
Karolina Piecyk
Eliza Rajkowska
Paulina Skrzypczyk
Jingping Geng
Edward Darzynkiewicz
Renata Grzela
Marzena Jankowska-Anyszka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1269028

3,307 views
1 citation

Original Research

Published on 05 Feb 2024

Virus sequencing performance during the SARS-CoV-2 pandemic: a retrospective analysis of data from multiple rounds of external quality assessment in Austria

in Molecular Diagnostics and Therapeutics

Jeremy V. Camp
Elisabeth Puchhammer-Stöckl
Stephan W. Aberle
Christoph Buchta

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1327699

2,204 views
1 citation

Review

Published on 05 Feb 2024

14-3-3 proteins—a moonlight protein complex with therapeutic potential in neurological disorder: in-depth review with Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Gholamareza Abdi
Mukul Jain
Nil Patil
Bindiya Upadhyay
Nigam Vyas
Manish Dwivedi
Radhey Shyam Kaushal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1286536

7,985 views
14 citations

Original Research

Published on 02 Feb 2024

Circulating miR-206, miR-181b, and miR-21 as promising biomarkers in hypothyroidism and their relationship to related hyperlipidemia and hepatic steatosis

in Molecular Diagnostics and Therapeutics

Asmaa Mohammed
Olfat G. Shaker
Mahmoud A. F. Khalil
Abeer K. Abu-El-Azayem
Amira Samy
Shaimaa A. Fathy
Mohamed M. K. AbdElguaad
Fatma A. M. Mahmoud
Randa Erfan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1307512

3,593 views
2 citations

Original Research

Published on 02 Feb 2024

Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach

in Molecular Diagnostics and Therapeutics

José Vicente Gil
Alberto Miralles
Sandra de las Heras
Esperanza Such
Gayane Avetisyan
Álvaro Díaz-González
Marta Santiago
Carolina Fuentes
José María Fernández
Pilar Lloret

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1362081

5,211 views
6 citations

Editorial

Published on 31 Jan 2024

Editorial: Platelets and their multi-faceted roles in health and disease

in Molecular Diagnostics and Therapeutics

Marta Zarà
Gianni Francesco Guidetti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1375090

2,939 views
2 citations

Original Research

Published on 31 Jan 2024

Longitudinal analysis of external quality assessment of immunoassay-based steroid hormone measurement indicates potential for improvement in standardization

in Molecular Diagnostics and Therapeutics

Laura Vierbaum
Nathalie Weiss
Patricia Kaiser
Marcel Kremser
Folker Wenzel
Mario Thevis
Ingo Schellenberg
Peter B. Luppa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1345356

4,182 views
2 citations

Editorial

Published on 25 Jan 2024

Editorial: Molecular mechanisms underlying obesity and their links with other comorbidities

in Molecular Diagnostics and Therapeutics

Julio Plaza-Diaz
Ana I. Álvarez-Mercado
Bilian Yu
Rungroch Sungthong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1334024

4,259 views
4 citations

Review

Published on 24 Jan 2024

The yeast 14-3-3 proteins Bmh1 and Bmh2 regulate key signaling pathways

in Molecular Diagnostics and Therapeutics

Veronika Obsilova
Tomas Obsil

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1327014

5,996 views
2 citations

Original Research

Published on 22 Jan 2024

Integrating clinical and cross-cohort metagenomic features: a stable and non-invasive colorectal cancer and adenoma diagnostic model

in Molecular Diagnostics and Therapeutics

Dan Zhou
Youli Chen
Zehao Wang
Siran Zhu
Lei Zhang
Jun Song
Tao Bai
Xiaohua Hou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1298679

2,937 views
3 citations

Brief Research Report

Published on 22 Jan 2024

Early prognosis prediction in acute myeloid and acute lymphoid leukemia patients using cell-free DNA concentration ratios

in Molecular Diagnostics and Therapeutics

Noreen Grace George
Bhavika Rishi
Amitabh Singh
Sree Vishmaya
Rakesh Kumar
Neetu Kushwaha
Manpreet Kaur
Reena Bhardwaj
Ankur Jain
Aditi Jain

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1333943

3,746 views
4 citations

Original Research

Published on 22 Jan 2024

Potential role for vitamin D vs. intermittent fasting in controlling aquaporin-1 and aquaporin-3 expression in HFD-induced urinary bladder alterations in rats

in Molecular Diagnostics and Therapeutics

Hend M. Hassan
Randa El-Gamal
Walaa. H. E. Hamed
Ola Ali Habotta
Mervat Samy
Rasha Elmowafy
Eman Mohamed ElNashar
Mansour Abdullah Alghamdi
Rashid A. Aldahhan
Khulood Mohammed Al-Khater

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1306523

3,651 views
4 citations