Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 26 May 2023

Prediction of prognosis and immunotherapy response in breast cancer based on neutrophil extracellular traps-related classification

in Molecular Diagnostics and Therapeutics

Jiajing Zhao
Xiaojun Xie

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165776

5,492 views
20 citations

Review

Published on 26 May 2023

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

in Molecular Diagnostics and Therapeutics

Katya Carbone
Fabio Gervasi
Latipa Kozhamzharova
Nazgul Altybaeva
Eda Sönmez Gürer
Javad Sharifi-Rad
Christophe Hano
Daniela Calina

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157558

7,222 views
20 citations

Methods

Published on 24 May 2023

Unsupervised neural network for single cell Multi-omics INTegration (UMINT): an application to health and disease

in Molecular Diagnostics and Therapeutics

Chayan Maitra
Dibyendu B. Seal
Vivek Das
Rajat K. De

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1184748

6,290 views
11 citations

Review

Published on 23 May 2023

DPP-4 inhibitors for treating T2DM - hype or hope? an analysis based on the current literature

in Molecular Diagnostics and Therapeutics

Kunika Saini
Smriti Sharma
Yousuf Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1130625

48,770 views
112 citations

Original Research

Published on 23 May 2023

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Yuanxin Shi
Peng Qiu
Kai Zhao
Xiangyu Li
Yunxiang Feng
Zhengdong Deng
Jianming Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165243

4,716 views
1 citation

Methods

Published on 22 May 2023

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

in Molecular Diagnostics and Therapeutics

Gerarda Cappuccio
Saleh M. Khalil
Sivan Osenberg
Feng Li
Mirjana Maletic-Savatic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1181965

10,568 views
15 citations

Original Research

Published on 19 May 2023

Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells

in Molecular Diagnostics and Therapeutics

Maria Carmen Rodenas
Julia Peñas-Martínez
Irene Pardo-Sánchez
David Zaragoza-Huesca
Carmen Ortega-Sabater
Jorge Peña-García
Salvador Espín
Guillermo Ricote
Sofía Montenegro
Francisco Ayala-De La Peña

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1182925

6,784 views
5 citations

Original Research

Published on 19 May 2023

FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC

in Molecular Diagnostics and Therapeutics

Hao Chi
Xinrui Gao
Zhijia Xia
Wanying Yu
Xisheng Yin
Yifan Pan
Gaoge Peng
Xinrui Mao
Alexander Tobias Teichmann
Jing Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1200335

10,099 views
53 citations

Original Research

Published on 17 May 2023

Targeted transcriptomic analysis of pancreatic adenocarcinoma in EUS-FNA samples by NanoString technology

in Molecular Diagnostics and Therapeutics

L. Pedrosa
I. K. Araujo
M. Cuatrecasas
G. Soy
S. López
J. Maurel
C. Sánchez-Montes
C. Montironi
T. Saurí
O. Sendino

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1161893

5,609 views
4 citations

Review

Published on 17 May 2023

The human neurosecretome: extracellular vesicles and particles (EVPs) of the brain for intercellular communication, therapy, and liquid-biopsy applications

in Molecular Diagnostics and Therapeutics

Taliah Soleymani
Tzu-Yi Chen
Edgar Gonzalez-Kozlova
Navneet Dogra

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1156821

8,880 views
12 citations

Original Research

Published on 15 May 2023

Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network

in Molecular Diagnostics and Therapeutics

Cuncan Deng
Juzheng Peng
Cheng Yuan
Huafu Li
Wenchao Li
Hongwu Chu
Hongfa Wei
Yulong He
Leli Zeng
Mingyu Huo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1163977

3,877 views
4 citations

Brief Research Report

Published on 15 May 2023

Construction of VSVΔ51M oncolytic virus expressing human interleukin-12

in Molecular Diagnostics and Therapeutics

Rwaa H. Abdulal
Jana S. Malki
Ezdehar Ghazal
Ahdab A. Alsaieedi
Sarah A. Almahboub
Muhammad Yasir Khan
Reem M. Alsulaiman
Mazen M. Ghaith
Turki S. Abujamel
Magdah Ganash

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1190669

7,068 views
9 citations

Original Research

Published on 12 May 2023

Toll-like receptor 4 deficiency in mice impairs venous thrombus resolution

in Molecular Diagnostics and Therapeutics

Haixin Yuan
Xiaoxi Huang
Jie Ding

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165589

3,248 views
8 citations

Original Research

Published on 11 May 2023

Innovative retargeted oncolytic herpesvirus against nectin4-positive cancers

in Molecular Diagnostics and Therapeutics

Andrea Vannini
Federico Parenti
Cristina Forghieri
Catia Barboni
Anna Zaghini
Gabriella Campadelli-Fiume
Tatiana Gianni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1149973

5,519 views
5 citations

Review

Published on 11 May 2023

Ado-tratuzumab emtansine beyond breast cancer: therapeutic role of targeting other HER2-positive cancers

in Molecular Diagnostics and Therapeutics

Yang Zheng
Jiayu Zou
Chen Sun
Fu Peng
Cheng Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165781

7,341 views
9 citations

Original Research

Published on 11 May 2023

Exploring the shared gene signatures of smoking-related osteoporosis and chronic obstructive pulmonary disease using machine learning algorithms

in Molecular Diagnostics and Therapeutics

Haotian Wang
Shaoshuo Li
Baixing Chen
Mao Wu
Heng Yin
Yang Shao
Jianwei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1204031

5,398 views
3 citations

Review

Published on 11 May 2023

Emerging field: O-GlcNAcylation in ferroptosis

in Molecular Diagnostics and Therapeutics

Hongshuo Zhang
Juan Zhang
Haojie Dong
Ying Kong
Youfei Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1203269

11,480 views
30 citations

Editorial

Published on 10 May 2023

Editorial: Recent breakthroughs in the decoding of circulating nucleic acids and their applications to human diseases

in Molecular Diagnostics and Therapeutics

Sherien M. El-Daly
Roba M. Talaat
Maria Braoudaki
Rana A. Youness
William C. Cho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1203495

2,176 views
16 citations

Original Research

Published on 10 May 2023

Self-assembling and pH-responsive protein nanoparticle as potential platform for targeted tumor therapy

in Molecular Diagnostics and Therapeutics

Zhikun Xu
Xiaozhan Zhang
Wang Dong
Huifang lv
Lijie Zuo
Lifei Zhu
Ruining Wang
Xia Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1172100

2,977 views
4 citations

Original Research

Published on 09 May 2023

A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer

in Molecular Diagnostics and Therapeutics

Kathryn E. Ware
Beatrice C. Thomas
Pelumi D. Olawuni
Maya U. Sheth
Nathan Hawkey
M. Yeshwanth
Brian C. Miller
Katherine J. Vietor
Mohit Kumar Jolly
So Young Kim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1104505

5,755 views
9 citations

Review

Published on 09 May 2023

Exploring the therapeutic and anti-tumor properties of morusin: a review of recent advances

in Molecular Diagnostics and Therapeutics

Amna Hafeez
Zeeshan Khan
Muhammad Armaghan
Khushbukhat Khan
Eda Sönmez Gürer
Ahmad Faizal Abdull Razis
Babagana Modu
Zainab M. Almarhoon
William N. Setzer
Javad Sharifi-Rad

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1168298

7,262 views
18 citations

Mini Review

Published on 05 May 2023

Pyrroloquinoline-quinone to reduce fat accumulation and ameliorate obesity progression

in Molecular Diagnostics and Therapeutics

Nur Syafiqah Mohamad Ishak
Kazuto Ikemoto

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1200025

32,005 views
21 citations

Editorial

Published on 05 May 2023

Editorial: Insights in molecular diagnostics and therapeutics: 2022

in Molecular Diagnostics and Therapeutics

Matteo Becatti
William C. Cho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1209844

3,058 views
1 citation

Original Research

Published on 04 May 2023

A biochemical, theoretical and immunohistochemical study comparing the therapeutic efficacy of curcumin and taurine on T-2 toxin induced hepatotoxicity in rats

in Molecular Diagnostics and Therapeutics

Maryam H. Al-Zahrani
Maha J. Balgoon
Nagwa M. El-Sawi
Fawzia A. Alshubaily
Ebtihaj J. Jambi
Sohair M. Khojah
Raghad S. Baljoon
Nuha A. Alkhattabi
Lina A. Baz
Asmaa A. Alharbi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1172403

5,056 views
11 citations