Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 27 Sep 2023

Comparative assessment of Alzheimer’s disease-related biomarkers in plasma and neuron-derived extracellular vesicles: a nested case-control study

in Molecular Diagnostics and Therapeutics

Apostolos Manolopoulos
Francheska Delgado-Peraza
Maja Mustapic
Krishna Ananthu Pucha
Carlos Nogueras-Ortiz
Alexander Daskalopoulos
De’Larrian DeAnté Knight
Jeannie-Marie Leoutsakos
Esther S. Oh
Constantine G. Lyketsos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1254834

4,316 views
12 citations

Review

Published on 26 Sep 2023

Recent progress in the effect of ferroptosis of HSCs on the development of liver fibrosis

in Molecular Diagnostics and Therapeutics

Rui Tang
Jing Luo
Xiaoxia Zhu
Pengyu Miao
Hong Tang
Yue Jian
Sibei Ruan
Feng Ling
Mingxi Tang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1258870

4,547 views
8 citations

Original Research

Published on 22 Sep 2023

Uncovering the immune microenvironment and molecular subtypes of hepatitis B-related liver cirrhosis and developing stable a diagnostic differential model by machine learning and artificial neural networks

in Molecular Diagnostics and Therapeutics

Shengke Zhang
Chenglu Jiang
Lai Jiang
Haiqing Chen
Jinbang Huang
Jieying Zhang
Rui Wang
Hao Chi
Guanhu Yang
Gang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1275897

5,311 views
19 citations

Review

Published on 21 Sep 2023

Anti-nucleolin aptamer AS1411: an advancing therapeutic

in Molecular Diagnostics and Therapeutics

Alexander Van den Avont
Neelam Sharma-Walia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1217769

12,601 views
43 citations

Review

Published on 21 Sep 2023

Advances in the application of CRISPR-Cas technology in rapid detection of pathogen nucleic acid

in Molecular Diagnostics and Therapeutics

Xiaoping Li
Jiaye Zhong
Haoyu Li
Yinbiao Qiao
Xiaolei Mao
Huayan Fan
Yiwu Zhong
Saber Imani
Shusen Zheng
Jianhui Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1260883

5,985 views
12 citations

Original Research

Published on 19 Sep 2023

ARPC1B is a novel prognostic biomarker for kidney renal clear cell carcinoma and correlates with immune infiltration

in Molecular Diagnostics and Therapeutics

Yong-Fei Tang
Bin Qiao
Ya-Bing Huang
Ming Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1202524

3,216 views
3 citations

Review

Published on 15 Sep 2023

Theranostic in GLP-1R molecular imaging: challenges and emerging opportunities

in Molecular Diagnostics and Therapeutics

Yang Xie
Yudi Wang
Wenjie Pei
Yue Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1210347

3,096 views
2 citations

Review

Published on 12 Sep 2023

Biosafety and biohazard considerations of HSV-1–based oncolytic viral immunotherapy

in Molecular Diagnostics and Therapeutics

Elizabeth Robilotti
Nathalie C. Zeitouni
Marlana Orloff

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1178382

6,304 views
3 citations

Review

Published on 11 Sep 2023

A promising nucleic acid therapy drug: DNAzymes and its delivery system

in Molecular Diagnostics and Therapeutics

Lang Xiao
Yan Zhao
Meng Yang
Guangxin Luan
Ting Du
Shanshan Deng
Xu Jia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1270101

6,964 views
12 citations

Mini Review

Published on 11 Sep 2023

SARS-CoV-2 infection as a potential risk factor for the development of cancer

in Molecular Diagnostics and Therapeutics

Natalia Ogarek
Paulina Oboza
Magdalena Olszanecka-Glinianowicz
Piotr Kocelak

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1260776

19,603 views
11 citations

Mini Review

Published on 11 Sep 2023

Real-time monitoring strategies for optimization of in vitro transcription and quality control of RNA

in Molecular Diagnostics and Therapeutics

Kyung Hyun Lee
Jaehwi Song
Seongcheol Kim
Seung Ryul Han
Seong-Wook Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1229246

4,916 views
4 citations

Original Research

Published on 08 Sep 2023

A curated census of pathogenic and likely pathogenic UTR variants and evaluation of deep learning models for variant effect prediction

in Molecular Diagnostics and Therapeutics

Emma Bohn
Tammy T. Y. Lau
Omar Wagih
Tehmina Masud
Daniele Merico

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1257550

5,316 views
3 citations

Original Research

Published on 06 Sep 2023

Uniformly shaped harmonization combines human transcriptomic data from different platforms while retaining their biological properties and differential gene expression patterns

in Molecular Diagnostics and Therapeutics

Nicolas Borisov
Victor Tkachev
Alexander Simonov
Maxim Sorokin
Ella Kim
Denis Kuzmin
Betul Karademir-Yilmaz
Anton Buzdin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1237129

2,933 views
9 citations

Original Research

Published on 01 Sep 2023

Combining docking, molecular dynamics simulations, AD-MET pharmacokinetics properties, and MMGBSA calculations to create specialized protocols for running effective virtual screening campaigns on the autoimmune disorder and SARS-CoV-2 main protease

in Molecular Diagnostics and Therapeutics

Emmanuel Israel Edache
Adamu Uzairu
Paul Andrew Mamza
Gideon Adamu Shallangwa
Fatma Hilal Yagin
Nagwan Abdel Samee
Noha F. Mahmoud

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1254230

6,229 views
10 citations

Original Research

Published on 01 Sep 2023

Endotrophin as a risk marker of mortality and kidney complications in a type 1 diabetes cohort

in Molecular Diagnostics and Therapeutics

Alexandra Louise Møller
Ninna Hahn Tougaard
Daniel Guldager Kring Rasmussen
Federica Genovese
Pernille Falberg Rønn
Tine Willum Hansen
Morten Asser Karsdal
Peter Rossing

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1229579

3,105 views
1 citation

Editorial

Published on 31 Aug 2023

Editorial: Molecular genetics of cutaneous melanoma: current status and future direction-volume II

in Molecular Diagnostics and Therapeutics

Zaida Garcia-Casado
Cristina Pellegrini
William C. Cho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1273849

1,078 views