Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 11 Jun 2025

Loss of endothelial TRPC1 aggravates metabolic dysfunction in obesity via disrupting adipose tissue homeostasis

in Molecular Diagnostics and Therapeutics

Yihui Lan
Shiquan Wang
Yuan Chu
Yizhi Zhang
Yuan Liu
Fan Yu
Lei Feng
Yifei Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1619559

877 views

Editorial

Published on 10 Jun 2025

Editorial: The role of natural and synthetic antioxidants in the therapeutic targeting of oxidative stress

in Molecular Diagnostics and Therapeutics

Alessia Remigante
Sara Spinelli
Rossana Morabito
Valentina Mittova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1630095

818 views

Editorial

Published on 10 Jun 2025

Editorial: Exploring molecular recognition: integrating experimental and computational approaches

in Molecular Diagnostics and Therapeutics

Teresa Matamá
António Rego
Junmei Wang
Tarsila G. Castro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1637793

873 views

Editorial

Published on 06 Jun 2025

Editorial: Cancer biomarkers: molecular insights into diagnosis, prognosis, and risk prediction

in Molecular Diagnostics and Therapeutics

Matteo Becatti
Shaoquan Zheng
Giuseppe Bronte

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1636721

945 views

Original Research

Published on 06 Jun 2025

Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus

in Molecular Diagnostics and Therapeutics

Guanfei Zhao
Haolong Li
Yutong Miao
Linlin Cheng
Yuying Chen
Yuan Huang
Hongyun Zhao
Yongmei Liu
Yipei Jing
Shasha Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585847

1,112 views

Original Research

Published on 05 Jun 2025

Peripheral myelin protein 2 is underexpressed in early-onset colorectal cancer and inhibits metastasis

in Molecular Diagnostics and Therapeutics

Zhiyu Yu
Sen Wang
Peng Xu
Cheng Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1610003

673 views

Original Research

Published on 30 May 2025

An immune-related seven-gene signature for predicting lymph node metastasis in breast cancer

in Molecular Diagnostics and Therapeutics

Yun Hu
Lanqiao Sun
Jinhua Wang
Yuan Ji
Lili Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615524

1,067 views

Original Research

Published on 27 May 2025

Enhanced prognostic and immunomodulatory effects of novel cuproptosis-related long noncoding RNAs in wilms tumor

in Molecular Diagnostics and Therapeutics

Yadong Li
Mingjie Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1566551

876 views

Review

Published on 26 May 2025

Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus

in Molecular Diagnostics and Therapeutics

Alberto J. Nuñez-Selles
Rodolfo A. Nuñez-Musa
Rafael A. Guillen-Marmolejos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1611842

1,996 views

Original Research

Published on 26 May 2025

A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer

in Molecular Diagnostics and Therapeutics

Yinmeng Zhang
Jiawei Fan
Jiahui Zhao
He Zhu
Yan Xia
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615533

1,491 views

Review

Published on 26 May 2025

Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

in Molecular Diagnostics and Therapeutics

Chandra Kanta Bhusal
Shweta Sinha
Davinder Kaur
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573618

1,302 views

Review

Published on 22 May 2025

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

in Molecular Diagnostics and Therapeutics

Almohanad A. Alkayyal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615393

1,022 views

Editorial

Published on 22 May 2025

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

in Molecular Diagnostics and Therapeutics

Lin Zhang
Weiye Qian
Qingyu Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620512

873 views

Review

Published on 21 May 2025

A comprehensive review of diagnostic approaches for hepatitis D

in Molecular Diagnostics and Therapeutics

Wen-Hui Liu
Jia-Yue Cui
Miao Yu
Xiao-Dong Shi
Yi-Lin Che
Chu-Yan Wang
Xiu-Mei Chi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598784

1,257 views

Original Research

Published on 19 May 2025

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

in Molecular Diagnostics and Therapeutics

Etianne Martini Sasso
Natalie Eaton-Fitch
Peter Smith
Katsuhiko Muraki
Sonya Marshall-Gradisnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1582967

16,180 views

Brief Research Report

Published on 16 May 2025

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

in Molecular Diagnostics and Therapeutics

Hao Chen
Yang Zhong
Rongjie Feng
Xingyu Zhu
Kang Xu
Mingjie Kuang
Wei Chong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556736

1,358 views