Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 10 Mar 2023

High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma

in Molecular Diagnostics and Therapeutics

Neel I. Nissen
Astrid Z. Johansen
Inna M. Chen
Christina Jensen
Emilie A. Madsen
Carsten P. Hansen
Jeppe Thorlacius-Ussing
Morten Karsdal
Julia S. Johansen
Hadi M. H. Diab

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1158058

3,376 views
8 citations

Review

Published on 08 Mar 2023

Extracellular matrix stiffness—The central cue for skin fibrosis

in Molecular Diagnostics and Therapeutics

Kang Wang
Dongsheng Wen
Xuewen Xu
Rui Zhao
Feipeng Jiang
Shengqin Yuan
Yifan Zhang
Ya Gao
Qingfeng Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1132353

15,976 views
44 citations

Original Research

Published on 08 Mar 2023

RETRACTED: Deep multi-modal intermediate fusion of clinical record and time series data in mortality prediction

in Molecular Diagnostics and Therapeutics

Ke Niu
Ke Zhang
Xueping Peng
Yijie Pan
Naian Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1136071

7,602 views
22 citations

Original Research

Published on 07 Mar 2023

A novel myeloid cell marker genes related signature can indicate immune infiltration and predict prognosis of hepatocellular carcinoma: Integrated analysis of bulk and single-cell RNA sequencing

in Molecular Diagnostics and Therapeutics

Su-Su Zheng
Yan-Fang Wu
Bo-Heng Zhang
Cheng Huang
Tong-Chun Xue

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1118377

8,283 views
5 citations

Original Research

Published on 07 Mar 2023

Dithiocarbazate ligands and their Ni(II) complexes with potential biological activity: Structural, antitumor and molecular docking study

in Molecular Diagnostics and Therapeutics

Cássia de Q. O. Cavalcante
Tales H. A. da Mota
Diêgo M. de Oliveira
Érica C. M. Nascimento
João B. L. Martins
Fabio Pittella-Silva
Claudia C. Gatto

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1146820

4,113 views
9 citations

Mini Review

Published on 06 Mar 2023

A strategy for the treatment of gastrointestinal cancer: Targeting tumor senescent cells

in Molecular Diagnostics and Therapeutics

Yujing Liu
Qiang Zhang
Wenjing Ni
Guang Ji
Hanchen Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1139840

2,937 views
3 citations

Review

Published on 06 Mar 2023

Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer

in Molecular Diagnostics and Therapeutics

Tingting Li
Liang Han
Simin Ma
Weiji Lin
Xin Ba
Jiahui Yan
Ying Huang
Shenghao Tu
Kai Qin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1140325

6,494 views
21 citations

Original Research

Published on 06 Mar 2023

Characterization and role exploration of ferroptosis-related genes in osteoarthritis

in Molecular Diagnostics and Therapeutics

Xinyu Wang
Tianyi Liu
Cheng Qiu
Shunan Yu
Yanzhuo Zhang
Yueyang Sheng
Chengai Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1066885

6,897 views
15 citations

Original Research

Published on 03 Mar 2023

Assessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture model

in Molecular Diagnostics and Therapeutics

Nilu Dhungel
Reneau Youngblood
Min Chu
Jennifer Carroll
Ana-Maria Dragoi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1096326

6,046 views
7 citations

Editorial

Published on 03 Mar 2023

Editorial: Gynecological and gastrointestinal cancers: Recent advances in molecular diagnosis and targeted therapy

in Molecular Diagnostics and Therapeutics

Lan Zhang
Guan Wang
Lingjuan Zhu
Wei Wei
Jin Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1167337

2,152 views

Mini Review

Published on 02 Mar 2023

Molecular imaging of HER2 receptor: Targeting HER2 for imaging and therapy in nuclear medicine

in Molecular Diagnostics and Therapeutics

Daniela Miladinova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1144817

7,752 views
22 citations

Review

Published on 02 Mar 2023

Targeting macrophages in atherosclerosis using nanocarriers loaded with liver X receptor agonists: A narrow review

in Molecular Diagnostics and Therapeutics

Tong-Mei Yang
Miao Miao
Wen-Qian Yu
Xue Wang
Fang-Jie Xia
Yan-Jie Li
Shou-Dong Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1147699

6,023 views
21 citations

Review

Published on 28 Feb 2023

HSV: The scout and assault for digestive system tumors

in Molecular Diagnostics and Therapeutics

Sheng Li
Qingbo Li
Yi Ren
Jia Yi
Jinhe Guo
Xianbin Kong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1142498

6,791 views
4 citations

Original Research

Published on 27 Feb 2023

Exploring the active ingredients and potential mechanisms of action of sinomenium acutum in the treatment of rheumatoid arthritis based on systems biology and network pharmacology

in Molecular Diagnostics and Therapeutics

Nan Gong
Lin Wang
Lili An
YuanKun Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1065171

5,721 views
13 citations

Editorial

Published on 27 Feb 2023

Editorial: RNAs at the crossroads between effectors and targets; discovery and development of new drugs

in Molecular Diagnostics and Therapeutics

Federica Chiappori
Luca Mollica

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157440

1,479 views

Mini Review

Published on 27 Feb 2023

Protective effects of isoflavones on alcoholic liver diseases: Computational approaches to investigate the inhibition of ALDH2 with isoflavone analogues

in Molecular Diagnostics and Therapeutics

Wook Lee
Seung-Jin Kim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1147301

4,495 views
9 citations

Review

Published on 24 Feb 2023

Regulation of SUMOylation on RNA metabolism in cancers

in Molecular Diagnostics and Therapeutics

Yingting Cao
Caihu Huang
Xian Zhao
Jianxiu Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1137215

5,791 views
14 citations

Original Research

Published on 24 Feb 2023

The signature of pyroptosis-related gene prognostic and immune microenvironment in adrenocortical carcinoma

in Molecular Diagnostics and Therapeutics

Jun Gao
Dai Wang
Qingping Yang
Mengjie Tang
Jiayi Du
Leye He
Wei Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1131402

3,891 views
4 citations

Editorial

Published on 21 Feb 2023

Editorial: Cancer diagnostics in solid tumors-from pathology to precision oncology

in Molecular Diagnostics and Therapeutics

Umberto Malapelle
Pedro Borralho
Liang Wang
Fernando Schmitt

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1150641

2,429 views

Mini Review

Published on 16 Feb 2023

Metabolism-based approaches for autosomal dominant polycystic kidney disease

in Molecular Diagnostics and Therapeutics

Ivona Bakaj
Alessandro Pocai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1126055

10,380 views
9 citations

Original Research

Published on 15 Feb 2023

Soluble peptidoglycan fragments produced by Limosilactobacillus fermentum with antiproliferative activity are suitable for potential therapeutic development: A preliminary report

in Molecular Diagnostics and Therapeutics

Virginia Fuochi
Mariarita Spampinato
Alfio Distefano
Angelo Palmigiano
Domenico Garozzo
Chiara Zagni
Antonio Rescifina
Giovanni Li Volti
Pio Maria Furneri

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1082526

3,620 views
10 citations

Original Research

Published on 14 Feb 2023

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

in Molecular Diagnostics and Therapeutics

Ryia Illani Mohd Yunos
Nurul-Syakima Ab Mutalib
Jia-shiun Khoo
Sazuita Saidin
Muhiddin Ishak
Saiful Effendi Syafruddin
Francis Yew Fu Tieng
Najwa Farhah Md Yusof
Mohd Ridhwan Abd Razak
Norshahidah Mahamad Nadzir

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.997747

5,789 views
4 citations

Review

Published on 10 Feb 2023

The contradictory roles of macrophages in non-alcoholic fatty liver disease and primary liver cancer—Challenges and opportunities

in Molecular Diagnostics and Therapeutics

Marlene Sophia Kohlhepp
Hanyang Liu
Frank Tacke
Adrien Guillot

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1129831

10,450 views
22 citations

Review

Published on 09 Feb 2023

Companion diagnostic requirements for spatial biology using multiplex immunofluorescence and multispectral imaging

in Molecular Diagnostics and Therapeutics

Darren Locke
Clifford C. Hoyt

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1051491

18,488 views
28 citations

2,097 articles

articles

High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma

Extracellular matrix stiffness—The central cue for skin fibrosis

RETRACTED: Deep multi-modal intermediate fusion of clinical record and time series data in mortality prediction

A novel myeloid cell marker genes related signature can indicate immune infiltration and predict prognosis of hepatocellular carcinoma: Integrated analysis of bulk and single-cell RNA sequencing

Dithiocarbazate ligands and their Ni(II) complexes with potential biological activity: Structural, antitumor and molecular docking study

A strategy for the treatment of gastrointestinal cancer: Targeting tumor senescent cells

Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer

Characterization and role exploration of ferroptosis-related genes in osteoarthritis

Assessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture model

Editorial: Gynecological and gastrointestinal cancers: Recent advances in molecular diagnosis and targeted therapy

Molecular imaging of HER2 receptor: Targeting HER2 for imaging and therapy in nuclear medicine

Targeting macrophages in atherosclerosis using nanocarriers loaded with liver X receptor agonists: A narrow review

HSV: The scout and assault for digestive system tumors

Exploring the active ingredients and potential mechanisms of action of sinomenium acutum in the treatment of rheumatoid arthritis based on systems biology and network pharmacology

Editorial: RNAs at the crossroads between effectors and targets; discovery and development of new drugs

Protective effects of isoflavones on alcoholic liver diseases: Computational approaches to investigate the inhibition of ALDH2 with isoflavone analogues

Regulation of SUMOylation on RNA metabolism in cancers

The signature of pyroptosis-related gene prognostic and immune microenvironment in adrenocortical carcinoma

Editorial: Cancer diagnostics in solid tumors-from pathology to precision oncology

Metabolism-based approaches for autosomal dominant polycystic kidney disease

Soluble peptidoglycan fragments produced by Limosilactobacillus fermentum with antiproliferative activity are suitable for potential therapeutic development: A preliminary report

Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations

The contradictory roles of macrophages in non-alcoholic fatty liver disease and primary liver cancer—Challenges and opportunities

Companion diagnostic requirements for spatial biology using multiplex immunofluorescence and multispectral imaging