Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 16 Nov 2022

No safe renal warm ischemia time—The molecular network characteristics and pathological features of mild to severe ischemia reperfusion kidney injury

in Molecular Diagnostics and Therapeutics

Ya-Lei Chen
Huai-Kang Li
Lei Wang
Jian-Wen Chen
Xin Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1006917

4,705 views
19 citations

Mini Review

Published on 16 Nov 2022

Tetrazine bioorthogonal chemistry derived in vivo imaging

in Molecular Diagnostics and Therapeutics

Gaoxiang Zhao
Zhutie Li
Renshuai Zhang
Liman Zhou
Haibo Zhao
Hongfei Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1055823

10,610 views
21 citations

Original Research

Published on 15 Nov 2022

The presence of diabetic retinopathy closely associated with the progression of non-alcoholic fatty liver disease: A meta-analysis of observational studies

in Molecular Diagnostics and Therapeutics

Guo-heng Zhang
Tian-hao Yuan
Zhen-sheng Yue
Lin Wang
Guo-Rui Dou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1019899

3,928 views
14 citations

Correction

Published on 14 Nov 2022

Corrigendum: Systematic analysis of MCM3 in pediatric medulloblastoma via multi-omics analysis

in Molecular Diagnostics and Therapeutics

Liangliang Cao
Yang Zhao
Zhuangzhuang Liang
Jian Yang
Jiajia Wang
Shuaiwei Tian
Qinhua Wang
Baocheng Wang
Heng Zhao
Feng Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1076243

1,911 views
2 citations

Original Research

Published on 11 Nov 2022

Comprehensive analysis of the prognostic value and functions of prefoldins in hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Shanjia Ke
Shounan Lu
Chaoqun Wang
Yanan Xu
Miaoyu Bai
Hongjun Yu
Zhigang Feng
Bing Yin
Zihao Li
Jingjing Huang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.957001

4,796 views
4 citations

Original Research

Published on 11 Nov 2022

Comprehensive analyses of one-carbon metabolism related genes and their association with prognosis, tumor microenvironment, chemotherapy resistance and immunotherapy in lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Ning Zhou
Quanying Tang
Haochuan Yu
Tong Li
Fan Ren
Lingling Zu
Gang Chen
Jun Chen
Song Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1034208

4,826 views
8 citations

Review

Published on 10 Nov 2022

The application of exosomes in the treatment of triple-negative breast cancer

in Molecular Diagnostics and Therapeutics

John W. Weaver
Jinyu Zhang
Juan Rojas
Phillip R. Musich
Zhiqiang Yao
Yong Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1022725

10,584 views
24 citations

Original Research

Published on 09 Nov 2022

Identification of six hub genes and two key pathways in two rat renal fibrosis models based on bioinformatics and RNA-seq transcriptome analyses

in Molecular Diagnostics and Therapeutics

Yueqin Cai
Jingan Chen
Jingyan Liu
Keyan Zhu
Zhixing Xu
Jianan Shen
Dejun Wang
Lisheng Chu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1035772

5,249 views
7 citations

Original Research

Published on 08 Nov 2022

Identification of hub genes regulating the cell activity and function of adipose-derived stem cells under oxygen-glucose deprivation

in Molecular Diagnostics and Therapeutics

Zhenyu Yang
Wei Lu
Zuoliang Qi
Xiaonan Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1025690

2,455 views
2 citations

Review

Published on 08 Nov 2022

Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions

in Molecular Diagnostics and Therapeutics

Bethany Thurairajah
Andrew J. Hudson
Richard G. Doveston

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1043673

5,597 views
8 citations

Review

Published on 07 Nov 2022

The role of ageing and oxidative stress in intervertebral disc degeneration

in Molecular Diagnostics and Therapeutics

Pengfei Wen
Bolong Zheng
Binfei Zhang
Tao Ma
Linjie Hao
Yumin Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1052878

8,337 views
47 citations

Review

Published on 07 Nov 2022

A comprehensive survey on computational learning methods for analysis of gene expression data

in Molecular Diagnostics and Therapeutics

Nikita Bhandari
Rahee Walambe
Ketan Kotecha
Satyajeet P. Khare

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.907150

9,364 views
30 citations

Editorial

Published on 04 Nov 2022

Editorial: Bioengineered nanoparticles in cancer therapy, Volume II

in Molecular Diagnostics and Therapeutics

Payam Zarrintaj
Masoud Mozafari
Tomy J. Gutiérrez
Mohammad Reza Saeb

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1072239

1,535 views
1 citation

Correction

Published on 03 Nov 2022

Corrigendum: Transcription factors BARX1 and DLX4 contribute to progression of clear cell renal cell carcinoma via promoting proliferation and epithelial–mesenchymal transition

in Molecular Diagnostics and Therapeutics

Guoliang Sun
Yue Ge
Yangjun Zhang
Libin Yan
Xiaoliang Wu
Wei Ouyang
Zhize Wang
Beichen Ding
Yucong Zhang
Gongwei Long

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1026319

1,464 views

Correction

Published on 03 Nov 2022

Corrigendum: Exosomes: Potential biomarkers and functions in head and neck squamous cell carcinoma

in Molecular Diagnostics and Therapeutics

Ting Li
Juan Li
Haitao Wang
Jiayu Zhao
Mingze Yan
Hongjiang He
Shan Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1056179

1,272 views
6 citations

Review

Published on 03 Nov 2022

Ferroptosis and its role in skeletal muscle diseases

in Molecular Diagnostics and Therapeutics

Ying Wang
Zepeng Zhang
Weikai Jiao
Yanyan Wang
Xiuge Wang
Yunyun Zhao
Xuechun Fan
Lulu Tian
Xiangyan Li
Jia Mi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1051866

16,544 views
48 citations

Original Research

Published on 28 Oct 2022

A cutting-edge immunomodulatory interlinkage between HOTAIR and MALAT1 in tumor-associated macrophages in breast cancer: A personalized immunotherapeutic approach

in Molecular Diagnostics and Therapeutics

Hoda T. Amer
Reda A. Eissa
Hend M. El Tayebi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1032517

5,891 views
19 citations

Original Research

Published on 28 Oct 2022

Semi-supervised segmentation of metastasis lesions in bone scan images

in Molecular Diagnostics and Therapeutics

Qiang Lin
Runxia Gao
Mingyang Luo
Haijun Wang
Yongchun Cao
Zhengxing Man
Rong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.956720

4,202 views
13 citations

Review

Published on 28 Oct 2022

Inflammasomes and their roles in arthritic disease pathogenesis

in Molecular Diagnostics and Therapeutics

Gabsik Yang
Han Chang Kang
Yong-Yeon Cho
Hye Suk Lee
Joo Young Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1027917

6,579 views
17 citations

Review

Published on 28 Oct 2022

An overview of structural approaches to study therapeutic RNAs

in Molecular Diagnostics and Therapeutics

Luca Mollica
Francesca Anna Cupaioli
Grazisa Rossetti
Federica Chiappori

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1044126

8,040 views
7 citations

Mini Review

Published on 26 Oct 2022

Tissue management in precision medicine: What the pathologist needs to know in the molecular era

in Molecular Diagnostics and Therapeutics

Ricella Souza da Silva
Regina Pinto
Luis Cirnes
Fernando Schmitt

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.983102

6,653 views
11 citations

Original Research

Published on 26 Oct 2022

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

in Molecular Diagnostics and Therapeutics

Sravan Gopalkrishnashetty Sreenivasmurthy
Ashok Iyaswamy
Senthilkumar Krishnamoorthi
Rambabu N. Reddi
Ananth Kumar Kammala
Karthick Vasudevan
Sanjib Senapati
Zhou Zhu
Cheng-Fu Su
Jia Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1030534

7,194 views
33 citations

Original Research

Published on 25 Oct 2022

Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models

in Molecular Diagnostics and Therapeutics

Karthikeyan Selvarasu
Abhay Kumar Singh
Ashok Iyaswamy
Sravan Gopalkrishnashetty Sreenivasmurthy
Senthilkumar Krishnamoorthi
Amal Kanti Bera
Jian-Dong Huang
Siva Sundara Kumar Durairajan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1050768

5,823 views
29 citations

Review

Published on 25 Oct 2022

Regulation mechanism of ferroptosis and its research progress in tumor immunotherapy

in Molecular Diagnostics and Therapeutics

Jing Xu
Xiaolin Lin
Ting Han
Qingqing Zhou
Yang Su
Shuqing Jiang
Xiuying Xiao
Tengfei Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1045548

5,060 views
14 citations