Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 19 Mar 2025

Osteoporotic vertebral fractures and subsequent fractures: risk factors from a retrospective observational study of patients with osteoporosis

in Molecular Diagnostics and Therapeutics

Mingxing Fan
Ran Lu
Jiayuan Wu
Jie Huang
Yanming Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558052

617 views

Original Research

Published on 18 Mar 2025

Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target

in Molecular Diagnostics and Therapeutics

Fan Bu
Jifa Zhong
Ruiqian Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1506961

553 views

Original Research

Published on 13 Mar 2025

Investigation of sphingolipid-related genes in lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Jibin Mao
Li Li
Hui Sun
Jie Han
Jinqiao Li
Chang-Sheng Dong
Hongyu Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548655

760 views

Original Research

Published on 13 Mar 2025

Network pharmacology combined with untargeted metabolomics reveals the intervention mechanism and compatibility of chenpi-rougui herb pair in nonalcoholic fatty liver disease

in Molecular Diagnostics and Therapeutics

Jinlin Xu
Sen Li
Yuehui Jin
Huiwen Yao
Xu Hu
Shan Cao
Huimin Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1553162

1,022 views

Original Research

Published on 12 Mar 2025

Expression and distribution of activin-follistatin-inhibin axis in the urinary bladder

in Molecular Diagnostics and Therapeutics

Weipu Mao
Tracy Zhang
Huan Chen
Sagar Barge
Zongwei Wang
Aria Olumi
Seth Alper
Weiqun Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1519977

918 views

Original Research

Published on 12 Mar 2025

Integrative multi-omics analysis and machine learning refine global histone modification features in prostate cancer

in Molecular Diagnostics and Therapeutics

XiaoFeng He
QinTao Ge
WenYang Zhao
Chao Yu
HuiMing Bai
XiaoTong Wu
Jing Tao
WenHao Xu
Yunhua Qiu
Lei Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1557843

1,755 views

Original Research

Published on 07 Mar 2025

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

in Molecular Diagnostics and Therapeutics

Qingrong Ma
Kai Chen
Haiping Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548810

978 views

Brief Research Report

Published on 27 Feb 2025

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean area

in Molecular Diagnostics and Therapeutics

Maria Cristina Mazzarella
Stefano Cristiano
Dilia Rea
Nicola Mazzarella
Martina Addeo
Silvia Iannelli
Geppino Falco
Mariarita Brancaccio
Tiziana Angrisano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536953

1,095 views

Editorial

Published on 27 Feb 2025

Editorial: Role of fibroblast in cancer

in Molecular Diagnostics and Therapeutics

Xuezhen Zeng
Man Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1574538

594 views

Original Research

Published on 27 Feb 2025

Multitargeted biological actions of polydatin in preventing pseudogout acute attack

in Molecular Diagnostics and Therapeutics

Chiara Baggio
Paola Galozzi
Amelia Damasco
Vanni Lazzarin
Giampietro Ravagnan
Paolo Sfriso
Roberta Ramonda
Leonardo Punzi
Gianmaria Pennelli
Andrea Doria

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1553912

755 views

Review

Published on 26 Feb 2025

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

in Molecular Diagnostics and Therapeutics

Yu Zhang
Yanfeng Yi
Yinghao Shu
Xiaochen Ru
Shuaibing He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1528663

801 views

Original Research

Published on 26 Feb 2025

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

in Molecular Diagnostics and Therapeutics

Xiaoqing Li
Li Yang
Longfei Zhu
Jingying Sun
Cuixiang Xu
Lijun Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536477

917 views

Original Research

Published on 25 Feb 2025

Development of an enzyme-linked immunosorbent assay (ELISA) for determining neutrophil elastase (NE) – a potential useful marker of multi-organ damage observed in COVID-19 and post-Covid-19 (PCS)

in Molecular Diagnostics and Therapeutics

Joanna Adamiec-Mroczek
Joanna Kluz
Sandra Chwałek
Maciej Rabczyński
Kinga Gostomska-Pampuch
Łukasz Lewandowski
Marta Misiuk-Hojło
Beata Ponikowska
Goutam Chourasia
Ilias Dumas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542898

1,113 views

Original Research

Published on 25 Feb 2025

Q-Der: a next-generation CoQ10 analogue supercharging neuroprotection by combating oxidative stress and enhancing mitochondrial function

in Molecular Diagnostics and Therapeutics

Matteo Micucci
Federico Gianfanti
Sabrina Donati Zeppa
Giosuè Annibalini
Barbara Canonico
Fabiana Fanelli
Roberta Saltarelli
Riham Osman
Mariele Montanari
Daniele Lopez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1525103

708 views

Hypothesis and Theory

Published on 25 Feb 2025

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

in Molecular Diagnostics and Therapeutics

Xiangyang Wang
Jingxiao Li
Rong Qin
Yi Yin
Jiepin Li
Sitian Lin
Xi Zou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1523494

1,462 views

Correction

Published on 25 Feb 2025

Corrigendum: Role of ARRB1 in prognosis and immunotherapy: a pan-cancer analysis

in Molecular Diagnostics and Therapeutics

Yingquan Ye
Haili Jiang
Yue Wu
Gaoxiang Wang
Yi Huang
Weijie Sun
Mei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1577764

406 views