Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Review

Published on 02 May 2025

Epigenetic modifications in cardiac fibrosis: recent evidence of new pharmacological targets

in Molecular Diagnostics and Therapeutics

Marian Pérez
Mónica Gómez
Jairo Castellar-López
Patricio Araos
Evelyn Mendoza-Torres
Samir Bolívar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583446

1,253 views

Original Research

Published on 01 May 2025

Integrative multi-omics and Mendelian randomization analysis reveal SPP1+ tumor-associated macrophage-driven prognostic signature for hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Kai Lei
Yichun Lei
Zeyao Wang
Zhixin Ye
Jiawei Liu
Wenhao Chen
Caihong Zhou
Jinmei Tan
Shuxian Chen
Yifan Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1594610

2,221 views
1 citation

Original Research

Published on 01 May 2025

Predictive value of CPS combined with inflammatory markers for pathological remission of locally advanced head and neck squamous cell carcinoma after adjuvant immunochemotherapy

in Molecular Diagnostics and Therapeutics

Yudong Ning
Han Li
Yixuan Song
Yuqin He
Shaoyan Liu
Yang Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593742

1,060 views
2 citations

Review

Accepted on 30 Apr 2025

Review of Research Progress in Sepsis-Associated Acute Kidney Injury

in Molecular Diagnostics and Therapeutics

Wanning Nian
Weichen Tao
Haiyi Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1603392

246 views

Original Research

Published on 30 Apr 2025

Unraveling the role of histone acetylation in sepsis biomarker discovery

in Molecular Diagnostics and Therapeutics

Feng Cheng
Juxin Deng
Zhaoyang Du
Lei Li
Zhaolei Qiu
Min Zhu
Hongchang Zhao
Zhenjie Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1582181

1,532 views

Original Research

Published on 28 Apr 2025

MRI-based deep learning with clinical and imaging features to differentiate medulloblastoma and ependymoma in children

in Molecular Diagnostics and Therapeutics

Yasen Yimit
Parhat Yasin
Yue Hao
Abudouresuli Tuersun
Chencui Huang
Xiaoguang Zou
Ya Qiu
Yunling Wang
Mayidili Nijiati

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1570860

978 views

Review

Published on 28 Apr 2025

APOBEC in breast cancer: a dual player in tumor evolution and therapeutic response

in Molecular Diagnostics and Therapeutics

Haiqi Lu
Zelin Lu
Yufei Wang
Miaoqin Chen
Guangliang Li
Xian Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1604313

1,757 views

Original Research

Published on 25 Apr 2025

Mechanism study on the treatment of ulcerative colitis by Gegen Qinlian nano-preparation through promoting M2 macrophage polarization

in Molecular Diagnostics and Therapeutics

Jilei Li
Jiarui Cao
Zhenyu Zhang
Sizhe Wang
Meng Zhu
Lili Yang
Wenhui Ouyang
Chunzheng Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580874

1,749 views

Original Research

Published on 25 Apr 2025

Risk factors of colorectal cancer in middle-aged and elder adults in China: findings from the China health and retirement longitudinal study

in Molecular Diagnostics and Therapeutics

Lin Zhang
Yuyan Zhang
Yujia Huo
Yang Zhao
Aimin Xu
Zhining Liu
Qiaojun Hong
Huiming Tu
Junjie Huang
Li Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1333834

2,063 views

Original Research

Published on 24 Apr 2025

TNFAIP8L3 regulation of the TGF-β signaling pathway affects the proportion of macrophages during tumor antigen presentation and affects the prognosis of ovarian cancer

in Molecular Diagnostics and Therapeutics

Chaomin Yue
Xiao Zheng
Yuqing Ye
Danyang Li
Yanhong Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1566363

1,522 views

Review

Published on 24 Apr 2025

The oxidative-stress-senescence axis in keratoconus: new insights into corneal degeneration

in Molecular Diagnostics and Therapeutics

Maria Laura Passaro
Michele Rinaldi
Valentina Morgera
Antonia Feola
Vito Romano
Mario Troisi
Diego Strianese
Raffaele Piscopo
Samantha Messina
Antonella Romano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1539542

1,580 views

Original Research

Published on 23 Apr 2025

Systematic use of protein free energy changes for classifying variants of uncertain significance: the case of IFT140 in Mainzer-Saldino Syndrome

in Molecular Diagnostics and Therapeutics

Macarena Gajardo
José Luis Guerrero
Bárbara Poblete
Esperanza Bayyad
Ignacio Castro
Jorge Maturana
Jaime Tobar
Víctor Faúndes
Paola Krall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561380

1,245 views

Original Research

Published on 16 Apr 2025

Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia

in Molecular Diagnostics and Therapeutics

Wei Gong
Yan Wang
Qun Li
Yating Gao
Jie Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1557218

1,426 views

Correction

Published on 16 Apr 2025

Corrigendum: CircMIB1 inhibits glioma development and progression through a competing endogenous RNA interaction network

in Molecular Diagnostics and Therapeutics

Simin Chen
Longping Li
Wei Xu
Nanjiao Xie
Huiting Xu
Yongjun Zhou
Ying Zou
Kai Yi
Zuping Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599157

687 views

Correction

Published on 15 Apr 2025

Corrigendum: The high-throughput solid-phase extraction of cis-cyclo(L-Leu-L-Pro) and cis-cyclo(L-Phe-L-Pro) from Lactobacillus plantarum demonstrates efficacy against multidrug-resistant bacteria and influenza A (H3N2) virus

in Molecular Diagnostics and Therapeutics

Jaeyoung Son
Yeonju Hong
Hyeri Seong
Yoon Sin Oh
Min-Kyu Kwak

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1605848

739 views

Review

Published on 14 Apr 2025

Extracellular vesicles in triple-negative breast cancer: current updates, challenges and future prospects

in Molecular Diagnostics and Therapeutics

Prashant Kumar Tiwari
Anis Ahmad Chaudhary
Saurabh Gupta
Mandeep Chouhan
Himanshu Narayan Singh
Sarvesh Rustagi
Salah-Ud-Din Khan
Sanjay Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561464

1,796 views