Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 01 Oct 2024

Profiling genetic variants in cardiovascular disease genes among a Heterogeneous cohort of Mendelian conditions patients and electronic health records

in Molecular Diagnostics and Therapeutics

Nadia Akawi
Ghadeera Al Mansoori
Anwar Al Zaabi
Andrea Badics
Noura Al Dhaheri
Aisha Al Shamsi
Amal Al Tenaiji
Bashar Alzohily
Fatmah S. A. Almesmari
Hamad Al Hammadi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1451457

1,071 views

Editorial

Published on 30 Sep 2024

Editorial: Revisiting the challenges and opportunities in cancer drug resistance

in Molecular Diagnostics and Therapeutics

Tikam Chand Dakal
Narendra Kumar Sharma
Amit Sharma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1497754

550 views

Original Research

Published on 30 Sep 2024

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

in Molecular Diagnostics and Therapeutics

Dmitry Kamashev
Nina Shaban
Galina Zakharova
Alexander Modestov
Мargarita Kamynina
Sergey Baranov
Anton Buzdin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1470496

970 views
1 citation

Original Research

Published on 27 Sep 2024

HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

in Molecular Diagnostics and Therapeutics

Polona Megušar
Ewen D. D. Calder
Tina Vodopivec Seravalli
Sergeja Lebar
Louise J. Walport
Rok Sekirnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1443917

1,525 views

Original Research

Published on 23 Sep 2024

DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis

in Molecular Diagnostics and Therapeutics

Minglu Meng
Yingjiao Ma
Jianguo Xu
Gao Chen
Roshan Kumar Mahato

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1433557

689 views

Original Research

Published on 19 Sep 2024

Screening and identification of the hub genes in severe acute pancreatitis and sepsis

in Molecular Diagnostics and Therapeutics

Si-Jiu Yang
Yan Luo
Bao-He Chen
Ling-Hui Zhan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1425143

1,538 views

Review

Published on 17 Sep 2024

Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges

in Molecular Diagnostics and Therapeutics

Philemon Ubanako
Sheefa Mirza
Paul Ruff
Clement Penny

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1447953

2,339 views

Original Research

Published on 16 Sep 2024

The synergistic effects of anoikis-related genes and EMT-related genes in the prognostic prediction of Wilms tumor

in Molecular Diagnostics and Therapeutics

Kexin Meng
Zerui Zhao
Yaqing Gao
Keliang Wu
Wei Liu
Xiaoqing Wang
Yi Zheng
Wei Zhao
Bei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1469775

1,164 views

Original Research

Published on 13 Sep 2024

The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study

in Molecular Diagnostics and Therapeutics

Chao Song
Zhenkui Hu
Jinhui Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1429372

800 views

Original Research

Published on 13 Sep 2024

Identification and mechanistic analysis of neurovascular coupling related biomarkers for diabetic macular edema

in Molecular Diagnostics and Therapeutics

Tianpeng Chen
Shufan Sheng
Jing Chen
Xiaole Wang
Yanxing Shang
Chengwei Duan
Caixia Liang
Yu Song
Dongmei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1332842

847 views

Original Research

Published on 12 Sep 2024

Identification of ATRNL1 and WNT9A as novel key genes and drug candidates in hypertrophic cardiomyopathy: integrative bioinformatics and experimental validation

in Molecular Diagnostics and Therapeutics

Huabin He
Yanhui Liao
Yang Chen
Hao Qin
Longlong Hu
Shucai Xiao
Huijian Wang
Renqiang Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1458434

1,542 views
1 citation

Editorial

Published on 12 Sep 2024

Editorial: Lessons from external quality control in laboratory medicine: important implications for public health!

in Molecular Diagnostics and Therapeutics

Nathalie Weiss
Ingo Schellenberg
Klaus-Peter Hunfeld

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485193

577 views

Retraction

Published on 11 Sep 2024

Retraction: Identification of a novel ferroptosis inducer for gastric cancer treatment using drug repurposing strategy

in Molecular Diagnostics and Therapeutics

Frontiers Editorial Office

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1491755

554 views

Hypothesis and Theory

Published on 11 Sep 2024

Disease-related data patterns in cerebrospinal fluid diagnostics: medical quality versus analytical quantity

in Molecular Diagnostics and Therapeutics

Hansotto Reiber

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1348091

800 views

Review

Published on 03 Sep 2024

MicroRNAs: emerging biomarkers and therapeutic targets in pancreatic cancer

in Molecular Diagnostics and Therapeutics

Jiaqian Yuan
Kaiqi Yan
Yong Guo
Yan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1457875

1,084 views

Review

Published on 02 Sep 2024

Targeting Death Receptor 5 (DR5) for the imaging and treatment of primary bone and soft tissue tumors: an update of the literature

in Molecular Diagnostics and Therapeutics

Zakareya Gamie
Anja Krippner-Heidenreich
Craig Gerrand
Kenneth Samora Rankin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1384795

4,385 views
1 citation

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Articles

Profiling genetic variants in cardiovascular disease genes among a Heterogeneous cohort of Mendelian conditions patients and electronic health records

Editorial: Revisiting the challenges and opportunities in cancer drug resistance

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA

DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis

Screening and identification of the hub genes in severe acute pancreatitis and sepsis

Exosome-mediated delivery of siRNA molecules in cancer therapy: triumphs and challenges

The synergistic effects of anoikis-related genes and EMT-related genes in the prognostic prediction of Wilms tumor

The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study

Identification and mechanistic analysis of neurovascular coupling related biomarkers for diabetic macular edema

Identification of ATRNL1 and WNT9A as novel key genes and drug candidates in hypertrophic cardiomyopathy: integrative bioinformatics and experimental validation

Editorial: Lessons from external quality control in laboratory medicine: important implications for public health!

Retraction: Identification of a novel ferroptosis inducer for gastric cancer treatment using drug repurposing strategy

Disease-related data patterns in cerebrospinal fluid diagnostics: medical quality versus analytical quantity

MicroRNAs: emerging biomarkers and therapeutic targets in pancreatic cancer

Targeting Death Receptor 5 (DR5) for the imaging and treatment of primary bone and soft tissue tumors: an update of the literature