Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Editorial

Published on 10 Jun 2025

Editorial: Exploring molecular recognition: integrating experimental and computational approaches

in Molecular Diagnostics and Therapeutics

Teresa Matamá
António Rego
Junmei Wang
Tarsila G. Castro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1637793

1,903 views

Editorial

Published on 06 Jun 2025

Editorial: Cancer biomarkers: molecular insights into diagnosis, prognosis, and risk prediction

in Molecular Diagnostics and Therapeutics

Matteo Becatti
Shaoquan Zheng
Giuseppe Bronte

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1636721

2,582 views

Original Research

Published on 06 Jun 2025

Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus

in Molecular Diagnostics and Therapeutics

Guanfei Zhao
Haolong Li
Yutong Miao
Linlin Cheng
Yuying Chen
Yuan Huang
Hongyun Zhao
Yongmei Liu
Yipei Jing
Shasha Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585847

2,356 views
1 citation

Original Research

Published on 05 Jun 2025

Peripheral myelin protein 2 is underexpressed in early-onset colorectal cancer and inhibits metastasis

in Molecular Diagnostics and Therapeutics

Zhiyu Yu
Sen Wang
Peng Xu
Cheng Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1610003

1,655 views

Original Research

Published on 30 May 2025

An immune-related seven-gene signature for predicting lymph node metastasis in breast cancer

in Molecular Diagnostics and Therapeutics

Yun Hu
Lanqiao Sun
Jinhua Wang
Yuan Ji
Lili Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615524

2,422 views

Original Research

Published on 27 May 2025

Enhanced prognostic and immunomodulatory effects of novel cuproptosis-related long noncoding RNAs in wilms tumor

in Molecular Diagnostics and Therapeutics

Yadong Li
Mingjie Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1566551

1,508 views

Review

Published on 26 May 2025

Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus

in Molecular Diagnostics and Therapeutics

Alberto J. Nuñez-Selles
Rodolfo A. Nuñez-Musa
Rafael A. Guillen-Marmolejos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1611842

7,875 views
8 citations

Original Research

Published on 26 May 2025

A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer

in Molecular Diagnostics and Therapeutics

Yinmeng Zhang
Jiawei Fan
Jiahui Zhao
He Zhu
Yan Xia
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615533

3,412 views

Review

Published on 26 May 2025

Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

in Molecular Diagnostics and Therapeutics

Chandra Kanta Bhusal
Shweta Sinha
Davinder Kaur
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573618

4,850 views
8 citations

Review

Published on 22 May 2025

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

in Molecular Diagnostics and Therapeutics

Almohanad A. Alkayyal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615393

2,380 views

Editorial

Published on 22 May 2025

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

in Molecular Diagnostics and Therapeutics

Lin Zhang
Weiye Qian
Qingyu Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620512

1,509 views

Review

Published on 21 May 2025

A comprehensive review of diagnostic approaches for hepatitis D

in Molecular Diagnostics and Therapeutics

Wen-Hui Liu
Jia-Yue Cui
Miao Yu
Xiao-Dong Shi
Yi-Lin Che
Chu-Yan Wang
Xiu-Mei Chi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598784

4,101 views
1 citation

Original Research

Published on 19 May 2025

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

in Molecular Diagnostics and Therapeutics

Etianne Martini Sasso
Natalie Eaton-Fitch
Peter Smith
Katsuhiko Muraki
Sonya Marshall-Gradisnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1582967

24,701 views
3 citations

Original Research

Published on 16 May 2025

Integrating network pharmacology and experimental validation to reveal the anti-growth mechanism of panaxadiol against glioblastoma via calcium signaling

in Molecular Diagnostics and Therapeutics

Guobin Qiu
Zhiyong Wu
Dunhui Yang
Luqiu Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598413

1,981 views

Brief Research Report

Published on 16 May 2025

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

in Molecular Diagnostics and Therapeutics

Hao Chen
Yang Zhong
Rongjie Feng
Xingyu Zhu
Kang Xu
Mingjie Kuang
Wei Chong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556736

2,834 views
1 citation

Original Research

Published on 15 May 2025

Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Chenxuyu Zhang
Zheng Luo
Liang Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554304

3,907 views
1 citation

Original Research

Published on 15 May 2025

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

in Molecular Diagnostics and Therapeutics

Yinmeng Zhang
He Zhu
Jiawei Fan
Jiahui Zhao
Yan Xia
Nan Zhang
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599141

3,756 views

Editorial

Published on 15 May 2025

Editorial: Advancements and future challenges in molecular diagnostics and therapeutics

in Molecular Diagnostics and Therapeutics

Matteo Becatti
Masoud Mozafari
Roberta Risoluti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620909

1,848 views
1 citation

Original Research

Published on 14 May 2025

Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Roberta Marongiu
Jimcy Platholi
Laibaik Park
Fangmin Yu
Garrett Sommer
Clara Woods
Teresa A. Milner
Michael J. Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597130

3,823 views
2 citations

Original Research

Published on 14 May 2025

A LODDS-based nomogram for overall and cancer-specific survival in stage III-IV gastric signet ring cell carcinoma

in Molecular Diagnostics and Therapeutics

Cenzhu Wang
Ying Fang
Yuhan Zhang
Shuhan Feng
Rui Hou
Hanfang Fan
Zeyu Wang
Lei Liu
Junli Ding
Junying Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1600626

2,266 views
1 citation

Review

Published on 13 May 2025

Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities

in Molecular Diagnostics and Therapeutics

Ziling Pang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578693

2,317 views
3 citations

Original Research

Published on 12 May 2025

Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head

in Molecular Diagnostics and Therapeutics

Ming-gang Guo
Chen-fei Yang
Fa Yuan
Tao Yang
Ping-yuan Luo
Yu-bai He
Shuan Yang
Feng Chen
Wei Li
Zhi-wei Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578755

3,339 views

Review

Published on 12 May 2025

The significance of calcium ions in cerebral ischemia-reperfusion injury: mechanisms and intervention strategies

in Molecular Diagnostics and Therapeutics

Yong-Wang Li
Yu Liu
Sheng-Zhen Luo
Xiao-Juan Huang
Yan Shen
Wei-Si Wang
Zhi-Chen Lang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585758

3,805 views
4 citations

Original Research

Published on 12 May 2025

New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics

in Molecular Diagnostics and Therapeutics

Xue Fan
Ying Li
Yuehao Xu
Jianqing Lin
Xin Guo
Jinwen Liao
Mingguo Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597412

2,468 views

2,097 articles

articles

Editorial: Exploring molecular recognition: integrating experimental and computational approaches

Editorial: Cancer biomarkers: molecular insights into diagnosis, prognosis, and risk prediction

Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus

Peripheral myelin protein 2 is underexpressed in early-onset colorectal cancer and inhibits metastasis

An immune-related seven-gene signature for predicting lymph node metastasis in breast cancer

Enhanced prognostic and immunomodulatory effects of novel cuproptosis-related long noncoding RNAs in wilms tumor

Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus

A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer

Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

A comprehensive review of diagnostic approaches for hepatitis D

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

Integrating network pharmacology and experimental validation to reveal the anti-growth mechanism of panaxadiol against glioblastoma via calcium signaling

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

Editorial: Advancements and future challenges in molecular diagnostics and therapeutics

Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

A LODDS-based nomogram for overall and cancer-specific survival in stage III-IV gastric signet ring cell carcinoma

Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities

Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head

The significance of calcium ions in cerebral ischemia-reperfusion injury: mechanisms and intervention strategies

New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics