Frontiers in Molecular Biosciences

Original Research

Published on 11 Aug 2022

Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis

in Structural Biology

Alessia Ruggiero
Han-Gyu Choi
Giovanni Barra
Flavia Squeglia
Young Woo Back
Hwa-Jung Kim
Rita Berisio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.964645

2,183 views
6 citations

Original Research

Published on 05 Aug 2022

It started with a Cys: Spontaneous cysteine modification during cryo-EM grid preparation

in Structural Biology

David P. Klebl
Yiheng Wang
Frank Sobott
Rebecca F. Thompson
Stephen P. Muench

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.945772

4,925 views
8 citations

Original Research

Published on 22 Jul 2022

Large-Scale Conformational Changes of FhaC Provide Insights Into the Two-Partner Secretion Mechanism

in Structural Biology

Giuseppe Sicoli
Albert Konijnenberg
Jérémy Guérin
Steve Hessmann
Elise Del Nero
Oscar Hernandez-Alba
Sophie Lecher
Guillaume Rouaut
Linn Müggenburg
Hervé Vezin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.950871

2,378 views
3 citations

Original Research

Published on 22 Jul 2022

The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16

in Structural Biology

Xiaolu Cheng
George Khelashvili
Harel Weinstein

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.903972

2,060 views
7 citations

Review

Published on 22 Jul 2022

Redesigning Enzymes for Biocatalysis: Exploiting Structural Understanding for Improved Selectivity

in Structural Biology

Yaoyu Ding
Gustavo Perez-Ortiz
Jessica Peate
Sarah M. Barry

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.908285

7,724 views
20 citations

Original Research

Published on 18 Jul 2022

Integrative Conformational Ensembles of Sic1 Using Different Initial Pools and Optimization Methods

in Structural Biology

Gregory-Neal W. Gomes
Ashley Namini
Claudiu C. Gradinaru

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.910956

3,189 views
12 citations

Editorial

Published on 14 Jul 2022

Editorial: Tailored Modulation of Interactions Between Biomolecules: Fundamentals and Applications

in Structural Biology

Matteo Ardini
Paola Baiocco
Adele Di Matteo
Giorgio Giardina
Adriana Erica Miele

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.961452

1,465 views
1 citation

Mini Review

Published on 14 Jul 2022

An Extended C-Terminus, the Possible Culprit for Differential Regulation of 5-Aminolevulinate Synthase Isoforms

in Structural Biology

Gregory A. Hunter
Gloria C. Ferreira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.920668

2,758 views
6 citations

Original Research

Published on 14 Jul 2022

The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli

in Structural Biology

Simen Hermansen
David Ryoo
Marcella Orwick-Rydmark
Athanasios Saragliadis
James C. Gumbart
Dirk Linke

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.918480

3,369 views
6 citations

Editorial

Published on 13 Jul 2022

Editorial: Nucleic Acid Polymerases: The Two-Metal-Ion Mechanism and Beyond

in Structural Biology

Janice D. Pata
Y. Whitney Yin
Indrajit Lahiri

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.948326

1,728 views

Review

Published on 13 Jul 2022

Developing Graphene Grids for Cryoelectron Microscopy

in Structural Biology

Hongcheng Fan
Fei Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.937253

11,023 views
11 citations

Review

Published on 12 Jul 2022

Structural Requirements and Plasticity of Receptor-Binding Domain in Human Coronavirus Spike

in Structural Biology

Yajuan Li
Peiyi Zheng
Tingting Liu
Cuixiao Shi
Bo Wang
Yuanhong Xu
Tengchuan Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.930931

4,569 views
6 citations

Original Research

Published on 11 Jul 2022

Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C

in Structural Biology

Maxime Killer
Giada Finocchio
Haydyn D. T. Mertens
Dmitri I. Svergun
Els Pardon
Jan Steyaert
Christian Löw

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.917725

3,930 views
8 citations

Original Research

Published on 07 Jul 2022

Impact of Bioconjugation on Structure and Function of Antibodies for Use in Immunoassay by Hydrogen-Deuterium Exchange Mass Spectrometry

in Structural Biology

Luise Luckau
Kate Groves
Chris Blencowe
Sam Scrimshaw
Alastair Dent
Milena Quaglia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.866843

3,038 views
1 citation

Review

Published on 06 Jul 2022

Quantitative Cryo-Electron Tomography

in Structural Biology

Paula P. Navarro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.934465

12,024 views
16 citations

Methods

Published on 06 Jul 2022

Accelerated 2D Classification With ISAC Using GPUs

in Structural Biology

Fabian Schöenfeld
Markus Stabrin
Tanvir R. Shaikh
Thorsten Wagner
Stefan Raunser

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.919994

3,592 views
7 citations