Frontiers in Molecular Biosciences

Mini Review

Published on 13 Jun 2022

Recent Molecular Insights into Agonist-specific Binding to the Mu-Opioid Receptor

in Structural Biology

Ferenc Zádor
Kornél Király
Nariman Essmat
Mahmoud Al-Khrasani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.900547

2,908 views
4 citations

Original Research

Published on 13 Jun 2022

AlphaFold Models of Small Proteins Rival the Accuracy of Solution NMR Structures

in Structural Biology

Roberto Tejero
Yuanpeng Janet Huang
Theresa A. Ramelot
Gaetano T. Montelione

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.877000

8,423 views
40 citations

Hypothesis and Theory

Published on 09 Jun 2022

How Honey Bee Vitellogenin Holds Lipid Cargo: A Role for the C-Terminal

in Structural Biology

Vilde Leipart
Øyvind Halskau
Gro V. Amdam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.865194

3,203 views
3 citations

Original Research

Published on 09 Jun 2022

New β-Propellers Are Continuously Amplified From Single Blades in all Major Lineages of the β-Propeller Superfamily

in Structural Biology

Joana Pereira
Andrei N. Lupas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.895496

3,470 views
6 citations

Original Research

Published on 08 Jun 2022

Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions

in Structural Biology

Takeshi Hiromoto
Teikichi Ikura
Eijiro Honjo
Michael Blaber
Ryota Kuroki
Taro Tamada

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.908394

2,522 views
3 citations

Original Research

Published on 06 Jun 2022

Characterization and Value Assignment of a Monoclonal Antibody Reference Material, NMIJ RM 6208a, AIST-MAB

in Structural Biology

Tomoya Kinumi
Kazumi Saikusa
Megumi Kato
Reiko Kojima
Chieko Igarashi
Naohiro Noda
Shinya Honda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.842041

6,338 views
7 citations

Original Research

Published on 01 Jun 2022

DEER Data Analysis Software: A Comparative Guide

in Structural Biology

Hannah Russell
Robyn Cura
Janet E. Lovett

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.915167

4,840 views
9 citations

Original Research

Published on 30 May 2022

Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design

in Structural Biology

Sherine E. Thomas
William J. McCarthy
Jamal El Bakali
Karen P. Brown
So Yeon Kim
Michal Blaszczyk
Vítor Mendes
Chris Abell
R. Andres Floto
Anthony G. Coyne

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.880432

3,569 views
7 citations

Methods

Published on 27 May 2022

Light ‘Em up: Efficient Screening of Gold Foil Grids in Cryo-EM

in Structural Biology

Wim J. H. Hagen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.912363

6,628 views
7 citations

Review

Published on 24 May 2022

Structural Details of BH3 Motifs and BH3-Mediated Interactions: an Updated Perspective

in Structural Biology

Valentina Sora
Elena Papaleo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.864874

5,634 views
16 citations

Review

Published on 23 May 2022

Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs

in Structural Biology

Toon Laeremans
Zara A. Sands
Pieter Claes
Ann De Blieck
Stephane De Cesco
Sarah Triest
Andreas Busch
David Felix
Abhinav Kumar
Veli-Pekka Jaakola

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.863099

22,718 views
32 citations

Brief Research Report

Published on 23 May 2022

Biochemical Characterization of SARS-CoV-2 Spike RBD Mutations and Their Impact on ACE2 Receptor Binding

in Structural Biology

Abdullah Hoter
Hassan Y. Naim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.893843

3,103 views
4 citations

Original Research

Published on 20 May 2022

Shape Complementarity Optimization of Antibody–Antigen Interfaces: The Application to SARS-CoV-2 Spike Protein

in Structural Biology

Alfredo De Lauro
Lorenzo Di Rienzo
Mattia Miotto
Pier Paolo Olimpieri
Edoardo Milanetti
Giancarlo Ruocco

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.874296

3,169 views
9 citations

Perspective

Published on 16 May 2022

Measuring Protein Aggregation and Stability Using High-Throughput Biophysical Approaches

in Structural Biology

Tristan O. C. Kwan
Stefan A. Kolek
Amy E. Danson
Rosana I. Reis
Ines S. Camacho
Patrick D. Shaw Stewart
Isabel Moraes

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.890862

8,821 views
14 citations

Original Research

Published on 11 May 2022

Targeting the Essential Transcription Factor HP1043 of Helicobacter pylori: A Drug Repositioning Study

in Structural Biology

Federico Antoniciello
Davide Roncarati
Annamaria Zannoni
Elena Chiti
Vincenzo Scarlato
Federica Chiappori

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.887564

3,476 views
4 citations

Original Research

Published on 09 May 2022

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels

in Structural Biology

Filip Koniuszewski
Florian D. Vogel
Konstantina Bampali
Jure Fabjan
Thomas Seidel
Petra Scholze
Philip B. Schmiedhofer
Thierry Langer
Margot Ernst

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.860246

3,806 views
10 citations