Frontiers in Molecular Biosciences

Original Research

Published on 03 Jul 2018

Structural and Functional Insights Into Lysostaphin–Substrate Interaction

in Structural Biology

Helena Tossavainen
Vytas Raulinaitis
Linda Kauppinen
Ulla Pentikäinen
Hannu Maaheimo
Perttu Permi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00060

11,817 views
38 citations

Review

Published on 19 Jun 2018

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

in Structural Biology

Karim Housseini B Issa
Gilles Phan
Isabelle Broutin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00057

25,809 views
64 citations

Review

Published on 12 Jun 2018

Biochemical Properties of Human D-amino Acid Oxidase Variants and Their Potential Significance in Pathologies

in Structural Biology

Silvia Sacchi
Pamela Cappelletti
Giulia Murtas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00055

7,862 views
37 citations

Original Research

Published on 12 Jun 2018

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

in Structural Biology

Chitra Narayanan
David N. Bernard
Khushboo Bafna
Donald Gagné
Pratul K. Agarwal
Nicolas Doucet

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00054

4,996 views
26 citations

Protocols

Published on 04 Jun 2018

Benchmarking cryo-EM Single Particle Analysis Workflow

in Structural Biology

Laura Y. Kim
William J. Rice
Edward T. Eng
Mykhailo Kopylov
Anchi Cheng
Ashleigh M. Raczkowski
Kelsey D. Jordan
Daija Bobe
Clinton S. Potter
Bridget Carragher

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00050

22,500 views
44 citations

Review

Published on 25 May 2018

Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase

in Structural Biology

Andrew L. Lee
Paul J. Sapienza

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00047

4,504 views
14 citations

Review

Published on 14 May 2018

The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics

in Structural Biology

Yury S. Polikanov
Nikolay A. Aleksashin
Bertrand Beckert
Daniel N. Wilson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00048

54,545 views
119 citations

Mini Review

Published on 30 Apr 2018

Intramolecular Fuzzy Interactions Involving Intrinsically Disordered Domains

in Structural Biology

Miguel Arbesú
Guillermo Iruela
Héctor Fuentes
João M. C. Teixeira
Miquel Pons

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00039

9,258 views
80 citations

Original Research

Published on 19 Apr 2018

Stabilization of a Membrane-Associated Amyloid-β Oligomer for Its Validation in Alzheimer's Disease

in Structural Biology

Montserrat Serra-Batiste
James Tolchard
Fabrice Giusti
Manuela Zoonens
Natàlia Carulla

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00038

5,719 views
15 citations

Mini Review

Published on 11 Apr 2018

The Use of NMR to Study Transient Carbohydrate—Protein Interactions

in Structural Biology

Pedro M. Nieto

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00033

5,122 views
14 citations

Review

Published on 06 Apr 2018

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals

in Structural Biology

Anutthaman Parthasarathy
Penelope J. Cross
Renwick C. J. Dobson
Lily E. Adams
Michael A. Savka
André O. Hudson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00029

108,519 views
316 citations

Original Research

Published on 02 Mar 2018

Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes

in Structural Biology

Ava Yuan Xue
Antonella Di Pizio
Anat Levit
Tali Yarnitzky
Osnat Penn
Tal Pupko
Masha Y. Niv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00009

7,086 views
16 citations

Review

Published on 23 Feb 2018

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases

in Structural Biology

Timothy Palzkill

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00016

36,119 views
182 citations

Mini Review

Published on 13 Feb 2018

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)

in Structural Biology

Nazanin R. Kondori
Praveen Paul
Jacqueline P. Robbins
Ke Liu
John C. W. Hildyard
Dominic J. Wells
Jacqueline S. de Belleroche

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00008

10,083 views
27 citations

Original Research

Published on 13 Feb 2018

Positive Charges on the Surface of Thaumatin Are Crucial for the Multi-Point Interaction with the Sweet Receptor

in Structural Biology

Tetsuya Masuda
Satomi Kigo
Mayuko Mitsumoto
Keisuke Ohta
Mamoru Suzuki
Bunzo Mikami
Naofumi Kitabatake
Fumito Tani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00010

8,161 views
15 citations

Original Research

Published on 13 Feb 2018

Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.

in Structural Biology

Morgan E. Milton
Bradley M. Minrovic
Danni L. Harris
Brian Kang
David Jung
Caleb P. Lewis
Richele J. Thompson
Roberta J. Melander
Daina Zeng
Christian Melander

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00015

9,733 views
27 citations

Perspective

Published on 08 Feb 2018

Free Energy, Enthalpy and Entropy from Implicit Solvent End-Point Simulations

in Structural Biology

Federico Fogolari
Alessandra Corazza
Gennaro Esposito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00011

18,893 views
22 citations

Original Research

Published on 06 Feb 2018

Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation

in Structural Biology

George P. Lisi
Allen A. Currier
J. Patrick Loria

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00004

6,397 views
32 citations

Original Research

Published on 02 Feb 2018

The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX

in Structural Biology

Salvatore Adinolfi
Rita Puglisi
Jason C. Crack
Clara Iannuzzi
Fabrizio Dal Piaz
Petr V. Konarev
Dmitri I. Svergun
Stephen Martin
Nick E. Le Brun
Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2017.00097

5,604 views
30 citations

Original Research

Published on 31 Jan 2018

Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors

in Structural Biology

Antonella Di Pizio
Nitzan Shy
Maik Behrens
Wolfgang Meyerhof
Masha Y. Niv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00006

6,025 views
17 citations

Review

Published on 24 Jan 2018

D-Amino Acid Oxidase-pLG72 Interaction and D-Serine Modulation

in Structural Biology

Loredano Pollegioni
Luciano Piubelli
Gianluca Molla
Elena Rosini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2018.00003

5,412 views
15 citations

Review

Published on 22 Jan 2018

Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance

in Structural Biology

Rebecca Clemens
Julia Zaschke-Kriesche
Sakshi Khosa
Sander H. J. Smits

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2017.00091

8,402 views
44 citations

Protocols

Published on 18 Jan 2018

Assays of D-Amino Acid Oxidase Activity

in Structural Biology

Elena Rosini
Laura Caldinelli
Luciano Piubelli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2017.00102

15,823 views
44 citations

Original Research

Published on 17 Jan 2018

Improved in Vitro Folding of the Y2 G Protein-Coupled Receptor into Bicelles

in Structural Biology

Peter Schmidt
Brian J. Bender
Anette Kaiser
Khushboo Gulati
Holger A. Scheidt
Heidi E. Hamm
Jens Meiler
Annette G. Beck-Sickinger
Daniel Huster

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2017.00100

6,868 views
24 citations

500 articles

articles

Structural and Functional Insights Into Lysostaphin–Substrate Interaction

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

Biochemical Properties of Human D-amino Acid Oxidase Variants and Their Potential Significance in Pathologies

Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

Benchmarking cryo-EM Single Particle Analysis Workflow

Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase

The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics

Intramolecular Fuzzy Interactions Involving Intrinsically Disordered Domains

Stabilization of a Membrane-Associated Amyloid-β Oligomer for Its Validation in Alzheimer's Disease

The Use of NMR to Study Transient Carbohydrate—Protein Interactions

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals

Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes

Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)

Positive Charges on the Surface of Thaumatin Are Crucial for the Multi-Point Interaction with the Sweet Receptor

Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.

Free Energy, Enthalpy and Entropy from Implicit Solvent End-Point Simulations

Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation

The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX

Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors

D-Amino Acid Oxidase-pLG72 Interaction and D-Serine Modulation

Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance

Assays of D-Amino Acid Oxidase Activity

Improved in Vitro Folding of the Y2 G Protein-Coupled Receptor into Bicelles