Frontiers in Molecular Biosciences

Original Research

Published on 16 Mar 2023

Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs

in Structural Biology

Phoebe A. Rice

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1113960

2,808 views

Editorial

Published on 15 Mar 2023

Editorial: Structural biology of nucleic acid replication, recombination and repair

in Structural Biology

Edward L. Bolt
Christopher D. O. Cooper
Nicholas P. Robinson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1155089

2,553 views

Editorial

Published on 09 Mar 2023

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development

in Structural Biology

Krishna M. Padmanabha Das

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165208

4,323 views
1 citation

Methods

Published on 07 Mar 2023

A simple flash and freeze system for cryogenic time-resolved electron microscopy

in Structural Biology

Biddut Bhattacharjee
Md Mahfuzur Rahman
Ryan E. Hibbs
Michael H. B. Stowell

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1129225

6,500 views
11 citations

Original Research

Published on 02 Mar 2023

Enhancing response of a protein conformational switch by using two disordered ligand binding domains

in Structural Biology

Harsimranjit Sekhon
Jeung-Hoi Ha
Stewart N. Loh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1114756

4,664 views
9 citations

Original Research

Published on 23 Feb 2023

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

in Structural Biology

Eva-Maria Zangerl-Plessl
Wei Wu
Michael C. Sanguinetti
Anna Stary-Weinzinger

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1137368

2,737 views
2 citations

Original Research

Published on 21 Feb 2023

Learned features of antibody-antigen binding affinity

in Structural Biology

Nathaniel L. Miller
Thomas Clark
Rahul Raman
Ram Sasisekharan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1112738

14,146 views
20 citations

Editorial

Published on 14 Feb 2023

Editorial: Intersection of biophysical and structural approaches in vaccine design

in Structural Biology

Christopher P. Ptak
Ching-Lin Hsieh
James A. Garnett
Rino Rappuoli
Yi-Pin Lin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1142656

2,786 views
1 citation

Mini Review

Published on 10 Feb 2023

Molecular mechanism of Rubisco activase: Dynamic assembly and Rubisco remodeling

in Structural Biology

Kazi Waheeda
Heidi Kitchel
Quan Wang
Po-Lin Chiu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1125922

19,027 views
38 citations

Original Research

Published on 09 Feb 2023

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

in Structural Biology

Miguel A. Minaya
Sidhartha Mahali
Abhirami K. Iyer
Abdallah M. Eteleeb
Rita Martinez
Guangming Huang
John Budde
Sally Temple
Alissa L. Nana
William W. Seeley

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1051494

8,565 views
29 citations

Methods

Published on 08 Feb 2023

Engineering the kinetic stability of a β-trefoil protein by tuning its topological complexity

in Structural Biology

Delaney M. Anderson
Lakshmi P. Jayanthi
Shachi Gosavi
Elizabeth M. Meiering

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1021733

3,902 views
1 citation

Editorial

Published on 06 Feb 2023

Editorial: From the hydrophobic core to the globular-disorder interface: New challenges and insights into protein design

in Structural Biology

Sankar Basu
Devlina Chakravarty
Qingzhen Hou
Vladimir N. Uversky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1151676

2,298 views
1 citation

Original Research

Published on 06 Feb 2023

Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches

in Structural Biology

Woong-Hee Shin
Keiko Kumazawa
Kenichiro Imai
Takatsugu Hirokawa
Daisuke Kihara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1110567

7,580 views
4 citations

Editorial

Published on 01 Feb 2023

Editorial: Integration of structural biology data in lead drug discovery and optimization

in Structural Biology

Pietro Roversi
Gianluca Molla
Marco Nardini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1145834

2,923 views
4 citations

Original Research

Published on 26 Jan 2023

Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems

in Structural Biology

Marcus Moldenhauer
Hsueh-Wei Tseng
Anastasia Kraskov
Neslihan N. Tavraz
Igor A. Yaroshevich
Peter Hildebrandt
Nikolai N. Sluchanko
Georg A. Hochberg
Lars-Oliver Essen
Nediljko Budisa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1072606

4,100 views
6 citations

Original Research

Published on 25 Jan 2023

Systematic analysis reveals novel insight into the molecular determinants of function, diversity and evolution of sweet taste receptors T1R2/T1R3 in primates

in Structural Biology

Congrui Wang
Yi Liu
Meng Cui
Bo Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1037966

5,718 views
7 citations

Editorial

Published on 23 Jan 2023

Editorial: Symmetry in protein architecture: Evolution, design, structure-function relationship, and applications

in Structural Biology

Michael Blaber
Suman Kundu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1140877

2,614 views
1 citation

Perspective

Published on 23 Jan 2023

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

in Structural Biology

Michael A. Hough
Filippo Prischi
Jonathan A. R. Worrall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1113762

7,870 views
11 citations

Editorial

Published on 17 Jan 2023

Editorial: Structure-function metrology of proteins

in Structural Biology

Alex R. Jones
Isabel Moraes
Milena Quaglia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1125791

2,235 views
1 citation

Original Research

Published on 13 Jan 2023

A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage

in Structural Biology

Rosanna Lucignano
Ilaria Stanzione
Giarita Ferraro
Rocco Di Girolamo
Carolina Cané
Angela Di Somma
Angela Duilio
Antonello Merlino
Delia Picone

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1008985

6,367 views
18 citations

Editorial

Published on 10 Jan 2023

Editorial: Aromatic amino acid metabolism–Volume II

in Structural Biology

Jianyong Li
David J. Merkler
Qian Han

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1122151

4,601 views
4 citations

Original Research

Published on 09 Jan 2023

Structural insights into 3Fe–4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450

in Structural Biology

Andrei Gilep
Tatsiana Varaksa
Sergey Bukhdruker
Anton Kavaleuski
Yury Ryzhykau
Sviatlana Smolskaya
Tatsiana Sushko
Kouhei Tsumoto
Irina Grabovec
Ivan Kapranov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1100032

7,238 views
13 citations

Original Research

Published on 09 Jan 2023

Regulating Shaker Kv channel clustering by hetero-oligomerization

in Structural Biology

Esraa Nsasra
Guy Peretz
Irit Orr
Ofer Yifrach

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1050942

2,022 views
1 citation

Review

Published on 09 Jan 2023

Twisting and swiveling domain motions in Cas9 to recognize target DNA duplexes, make double-strand breaks, and release cleaved duplexes

in Structural Biology

Jimin Wang
Pablo R. Arantes
Mohd Ahsan
Souvik Sinha
Gregory W. Kyro
Federica Maschietto
Brandon Allen
Erin Skeens
George P. Lisi
Victor S. Batista

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1072733

7,012 views
18 citations

501 articles

articles

Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs

Editorial: Structural biology of nucleic acid replication, recombination and repair

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development

A simple flash and freeze system for cryogenic time-resolved electron microscopy

Enhancing response of a protein conformational switch by using two disordered ligand binding domains

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

Learned features of antibody-antigen binding affinity

Editorial: Intersection of biophysical and structural approaches in vaccine design

Molecular mechanism of Rubisco activase: Dynamic assembly and Rubisco remodeling

Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling

Engineering the kinetic stability of a β-trefoil protein by tuning its topological complexity

Editorial: From the hydrophobic core to the globular-disorder interface: New challenges and insights into protein design

Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches

Editorial: Integration of structural biology data in lead drug discovery and optimization

Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems

Systematic analysis reveals novel insight into the molecular determinants of function, diversity and evolution of sweet taste receptors T1R2/T1R3 in primates

Editorial: Symmetry in protein architecture: Evolution, design, structure-function relationship, and applications

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

Editorial: Structure-function metrology of proteins

A new and efficient procedure to load bioactive molecules within the human heavy-chain ferritin nanocage

Editorial: Aromatic amino acid metabolism–Volume II

Structural insights into 3Fe–4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P450

Regulating Shaker Kv channel clustering by hetero-oligomerization

Twisting and swiveling domain motions in Cas9 to recognize target DNA duplexes, make double-strand breaks, and release cleaved duplexes