Frontiers in Molecular Biosciences

Review

Published on 30 Sep 2022

Prediction of protein-protein interaction sites in intrinsically disordered proteins

in Structural Biology

Ranran Chen
Xinlu Li
Yaqing Yang
Xixi Song
Cheng Wang
Dongdong Qiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.985022

8,194 views
16 citations

Original Research

Published on 28 Sep 2022

Improvement of native structure-based peptides as efficient inhibitors of protein-protein interactions of SARS-CoV-2 spike protein and human ACE2

in Structural Biology

Norbert Odolczyk
Joanna Klim
Małgorzata Podsiadła-Białoskórska
Maria Winiewska-Szajewska
Ewa Szolajska
Urszula Zielenkiewicz
Jarosław Poznański
Piotr Zielenkiewicz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.983014

3,497 views
6 citations

Original Research

Published on 21 Sep 2022

Rational design of photosynthetic reaction center protein maquettes

in Structural Biology

Nathan M. Ennist
Steven E. Stayrook
P. Leslie Dutton
Christopher C. Moser

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.997295

14,405 views
18 citations

Editorial

Published on 20 Sep 2022

Editorial: Oligomerization and fibrillation of amyloid peptides: Mechanism, toxicity and inhibition

in Structural Biology

Zhenyu Qian
Nabanita Saikia
Yunxiang Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1023047

1,745 views
5 citations

Review

Published on 16 Sep 2022

Structural insights into the functional roles of 14-3-3 proteins

in Structural Biology

Veronika Obsilova
Tomas Obsil

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1016071

22,751 views
106 citations

Methods

Published on 15 Sep 2022

Practices for running a research-oriented shared cryo-EM facility

in Structural Biology

Richard M. Walsh
Megan L. Mayer
Christopher H. Sun
Shaun Rawson
Remya Nair
Sarah M. Sterling
Zongli Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.960940

4,974 views
7 citations

Review

Published on 14 Sep 2022

Systemic tryptophan homeostasis

in Structural Biology

Simon Klaessens
Vincent Stroobant
Etienne De Plaen
Benoit J. Van den Eynde

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.897929

22,705 views
84 citations

Original Research

Published on 14 Sep 2022

In-silico investigation of systematic missense mutations of middle east respiratory coronavirus spike protein

in Structural Biology

Raina Rhoades
Adebiyi Sobitan
Vidhyanand Mahase
Brhan Gebremedhin
Qiyi Tang
Danda Rawat
Hongbao Cao
Shaolei Teng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.933553

3,536 views
3 citations

Review

Published on 12 Sep 2022

Allosteric regulation of substrate channeling: Salmonella typhimurium tryptophan synthase

in Structural Biology

Rittik K. Ghosh
Eduardo Hilario
Chia-en A. Chang
Leonard J. Mueller
Michael F. Dunn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.923042

5,198 views
11 citations

Original Research

Published on 08 Sep 2022

DeepHEMNMA: ResNet-based hybrid analysis of continuous conformational heterogeneity in cryo-EM single particle images

in Structural Biology

Ilyes Hamitouche
Slavica Jonic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.965645

5,155 views
33 citations

Original Research

Published on 07 Sep 2022

The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes

in Structural Biology

Giuliana Fusco
Francesco Bemporad
Fabrizio Chiti
Christopher M. Dobson
Alfonso De Simone

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.981312

4,310 views
11 citations

Original Research

Published on 26 Aug 2022

Some useful ideas for multistate protein design: Effect of amino acid substitutions on the multistate proteins stability and the rate of protein structure formation

in Structural Biology

M. A. Majorina
T. N. Melnik
A. S. Glukhov
B. S. Melnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.983009

3,346 views
4 citations

Original Research

Published on 25 Aug 2022

A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes

in Structural Biology

Luigi Scietti
Elisabetta Moroni
Daiana Mattoteia
Marco Fumagalli
Matteo De Marco
Lisa Negro
Antonella Chiapparino
Stefano A. Serapian
Francesca De Giorgi
Silvia Faravelli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.876352

5,731 views
6 citations

Original Research

Published on 19 Aug 2022

The intriguing dose-dependent effect of selected amphiphilic compounds on insulin amyloid aggregation: Focus on a cholesterol-based detergent, Chobimalt

in Structural Biology

Katarina Siposova
Viktor I. Petrenko
Ivana Garcarova
Dagmar Sedlakova
László Almásy
Olena A. Kyzyma
Manfred Kriechbaum
Andrey Musatov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.955282

2,574 views
7 citations

Brief Research Report

Published on 18 Aug 2022

Grid batch-dependent tuning of glow discharge parameters

in Structural Biology

Ramy Kazan
Gabrielle Bourgeois
Dominique Carisetti
Ileana Florea
Eric Larquet
Jean-Luc Maurice
Yves Mechulam
François Ozanam
Emmanuelle Schmitt
Pierre-Damien Coureux

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.910218

7,736 views
3 citations

Editorial

Published on 17 Aug 2022

Editorial: Molecular evolution: You learn from your mistakes

in Structural Biology

Marco Fantini
Edoardo Sarti
Gian Gaetano Tartaglia
Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.985289

1,848 views

Original Research

Published on 17 Aug 2022

Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation

in Structural Biology

Mohammed Bhogadia
Beth Stone
Rafael Del Villar Guerra
Frederick W. Muskett
Sudipta Ghosh
Andrea Taladriz-Sender
Glenn A. Burley
Ian C. Eperon
Andrew J. Hudson
Cyril Dominguez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.943105

7,804 views
1 citation

Original Research

Published on 16 Aug 2022

Developing methods to study conformational changes in RNA crystals using a photocaged ligand

in Structural Biology

Hyun Kyung Lee
Chelsie E. Conrad
Valentin Magidson
William F. Heinz
Gary Pauly
Ping Yu
Saminathan Ramakrishnan
Jason R. Stagno
Yun-Xing Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.964595

2,675 views
1 citation

Original Research

Published on 11 Aug 2022

Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis

in Structural Biology

Alessia Ruggiero
Han-Gyu Choi
Giovanni Barra
Flavia Squeglia
Young Woo Back
Hwa-Jung Kim
Rita Berisio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.964645

3,326 views
8 citations

Original Research

Published on 05 Aug 2022

It started with a Cys: Spontaneous cysteine modification during cryo-EM grid preparation

in Structural Biology

David P. Klebl
Yiheng Wang
Frank Sobott
Rebecca F. Thompson
Stephen P. Muench

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.945772

6,210 views
10 citations

Original Research

Published on 22 Jul 2022

The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16

in Structural Biology

Xiaolu Cheng
George Khelashvili
Harel Weinstein

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.903972

2,744 views
11 citations

Original Research

Published on 22 Jul 2022

Large-Scale Conformational Changes of FhaC Provide Insights Into the Two-Partner Secretion Mechanism

in Structural Biology

Giuseppe Sicoli
Albert Konijnenberg
Jérémy Guérin
Steve Hessmann
Elise Del Nero
Oscar Hernandez-Alba
Sophie Lecher
Guillaume Rouaut
Linn Müggenburg
Hervé Vezin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.950871

3,728 views
3 citations

Review

Published on 22 Jul 2022

Redesigning Enzymes for Biocatalysis: Exploiting Structural Understanding for Improved Selectivity

in Structural Biology

Yaoyu Ding
Gustavo Perez-Ortiz
Jessica Peate
Sarah M. Barry

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.908285

11,846 views
32 citations

Original Research

Published on 18 Jul 2022

Integrative Conformational Ensembles of Sic1 Using Different Initial Pools and Optimization Methods

in Structural Biology

Gregory-Neal W. Gomes
Ashley Namini
Claudiu C. Gradinaru

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.910956

4,061 views
12 citations

501 articles

articles

Prediction of protein-protein interaction sites in intrinsically disordered proteins

Improvement of native structure-based peptides as efficient inhibitors of protein-protein interactions of SARS-CoV-2 spike protein and human ACE2

Rational design of photosynthetic reaction center protein maquettes

Editorial: Oligomerization and fibrillation of amyloid peptides: Mechanism, toxicity and inhibition

Structural insights into the functional roles of 14-3-3 proteins

Practices for running a research-oriented shared cryo-EM facility

Systemic tryptophan homeostasis

In-silico investigation of systematic missense mutations of middle east respiratory coronavirus spike protein

Allosteric regulation of substrate channeling: Salmonella typhimurium tryptophan synthase

DeepHEMNMA: ResNet-based hybrid analysis of continuous conformational heterogeneity in cryo-EM single particle images

The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes

Some useful ideas for multistate protein design: Effect of amino acid substitutions on the multistate proteins stability and the rate of protein structure formation

A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes

The intriguing dose-dependent effect of selected amphiphilic compounds on insulin amyloid aggregation: Focus on a cholesterol-based detergent, Chobimalt

Grid batch-dependent tuning of glow discharge parameters

Editorial: Molecular evolution: You learn from your mistakes

Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation

Developing methods to study conformational changes in RNA crystals using a photocaged ligand

Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis

It started with a Cys: Spontaneous cysteine modification during cryo-EM grid preparation

The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16

Large-Scale Conformational Changes of FhaC Provide Insights Into the Two-Partner Secretion Mechanism

Redesigning Enzymes for Biocatalysis: Exploiting Structural Understanding for Improved Selectivity

Integrative Conformational Ensembles of Sic1 Using Different Initial Pools and Optimization Methods