Frontiers in Molecular Biosciences

Editorial

Published on 14 Jul 2022

Editorial: Tailored Modulation of Interactions Between Biomolecules: Fundamentals and Applications

in Structural Biology

Matteo Ardini
Paola Baiocco
Adele Di Matteo
Giorgio Giardina
Adriana Erica Miele

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.961452

2,019 views
2 citations

Mini Review

Published on 14 Jul 2022

An Extended C-Terminus, the Possible Culprit for Differential Regulation of 5-Aminolevulinate Synthase Isoforms

in Structural Biology

Gregory A. Hunter
Gloria C. Ferreira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.920668

3,904 views
8 citations

Original Research

Published on 14 Jul 2022

The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli

in Structural Biology

Simen Hermansen
David Ryoo
Marcella Orwick-Rydmark
Athanasios Saragliadis
James C. Gumbart
Dirk Linke

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.918480

4,811 views
10 citations

Editorial

Published on 13 Jul 2022

Editorial: Nucleic Acid Polymerases: The Two-Metal-Ion Mechanism and Beyond

in Structural Biology

Janice D. Pata
Y. Whitney Yin
Indrajit Lahiri

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.948326

3,064 views
1 citation

Review

Published on 13 Jul 2022

Developing Graphene Grids for Cryoelectron Microscopy

in Structural Biology

Hongcheng Fan
Fei Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.937253

13,370 views
15 citations

Review

Published on 12 Jul 2022

Structural Requirements and Plasticity of Receptor-Binding Domain in Human Coronavirus Spike

in Structural Biology

Yajuan Li
Peiyi Zheng
Tingting Liu
Cuixiao Shi
Bo Wang
Yuanhong Xu
Tengchuan Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.930931

6,064 views
8 citations

Original Research

Published on 11 Jul 2022

Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C

in Structural Biology

Maxime Killer
Giada Finocchio
Haydyn D. T. Mertens
Dmitri I. Svergun
Els Pardon
Jan Steyaert
Christian Löw

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.917725

5,630 views
10 citations

Original Research

Published on 07 Jul 2022

Impact of Bioconjugation on Structure and Function of Antibodies for Use in Immunoassay by Hydrogen-Deuterium Exchange Mass Spectrometry

in Structural Biology

Luise Luckau
Kate Groves
Chris Blencowe
Sam Scrimshaw
Alastair Dent
Milena Quaglia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.866843

4,359 views
3 citations

Review

Published on 06 Jul 2022

Quantitative Cryo-Electron Tomography

in Structural Biology

Paula P. Navarro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.934465

15,158 views
21 citations

Methods

Published on 06 Jul 2022

Accelerated 2D Classification With ISAC Using GPUs

in Structural Biology

Fabian Schöenfeld
Markus Stabrin
Tanvir R. Shaikh
Thorsten Wagner
Stefan Raunser

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.919994

5,080 views
7 citations

Original Research

Published on 04 Jul 2022

Impact of Formulation Choices on the Freeze-Drying of an Interleukin-6 Reference Material

in Structural Biology

Paul Matejtschuk
Christopher Bird
Ernest Ezeajughi
Kirsty MacLellan-Gibson
Meenu Wadhwa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.868460

6,142 views
2 citations

Original Research

Published on 04 Jul 2022

Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design

in Structural Biology

Annarita Fiorillo
Gianni Colotti
Cécile Exertier
Anastasia Liuzzi
Francesca Seghetti
Alessandra Salerno
Jessica Caciolla
Andrea Ilari

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.900882

4,985 views
12 citations

Original Research

Published on 28 Jun 2022

Photoactivation of a Mechanosensitive Channel

in Structural Biology

Fucsia Crea
Antreas Vorkas
Aoife Redlich
Rubén Cruz
Chaowei Shi
Dirk Trauner
Adam Lange
Ramona Schlesinger
Joachim Heberle

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.905306

6,098 views
15 citations

Original Research

Published on 28 Jun 2022

Wild-Type α-Synuclein and Variants Occur in Different Disordered Dimers and Pre-Fibrillar Conformations in Early Stage of Aggregation

in Structural Biology

Adrien Guzzo
Patrice Delarue
Ana Rojas
Adrien Nicolaï
Gia G. Maisuradze
Patrick Senet

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.910104

5,229 views
14 citations

Original Research

Published on 28 Jun 2022

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7

in Structural Biology

Baptiste Colcombet-Cazenave
Florence Cordier
Yanlei Zhu
Guillaume Bouvier
Eleni Litsardaki
Louise Laserre
Marie S. Prevost
Bertrand Raynal
Célia Caillet-Saguy
Nicolas Wolff

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.923740

4,792 views
5 citations

Brief Research Report

Published on 27 Jun 2022

Human Claudin-7 cis-Interactions Are Not Crucial for Membrane-Membrane (Trans-) Interactions

in Structural Biology

Lena Ahlswede
Carmen Siebenaller
Benedikt Junglas
Nadja Hellmann
Dirk Schneider

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.908383

2,948 views

Mini Review

Published on 27 Jun 2022

A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies

in Structural Biology

Clive Metcalfe

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.886417

8,991 views
11 citations

Editorial

Published on 27 Jun 2022

Editorial: Integrative Structural Biology of Proteins and Macromolecular Assemblies: Bridging Experiments and Simulations

in Structural Biology

Paulo Ricardo Batista
Mario Oliveira Neto
David Perahia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.947582

1,604 views
3 citations

Review

Published on 24 Jun 2022

Recent Technical Advances in Sample Preparation for Single-Particle Cryo-EM

in Structural Biology

Yixin Xu
Shangyu Dang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.892459

18,140 views
35 citations

Methods

Published on 23 Jun 2022

Biophysical Screening Pipeline for Cryo-EM Grid Preparation of Membrane Proteins

in Structural Biology

Stephan Niebling
Katharina Veith
Benjamin Vollmer
Javier Lizarrondo
Osvaldo Burastero
Janina Schiller
Angelica Struve García
Philipp Lewe
Carolin Seuring
Susanne Witt

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.882288

18,885 views
24 citations

Original Research

Published on 23 Jun 2022

Approaches to Using the Chameleon: Robust, Automated, Fast-Plunge cryoEM Specimen Preparation

in Structural Biology

Talya S. Levitz
Miriam Weckener
Ivan Fong
James H. Naismith
Catherine L. Drennan
Edward J. Brignole
Daniel K. Clare
Michele C. Darrow

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.903148

6,972 views
43 citations

Review

Published on 23 Jun 2022

OOP-ESEEM Spectroscopy: Accuracies of Distances of Spin-Correlated Radical Pairs in Biomolecules

in Structural Biology

Tarek Al Said
Stefan Weber
Erik Schleicher

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.890826

3,683 views
7 citations

Methods

Published on 17 Jun 2022

Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids

in Structural Biology

Brandon Huntington
Lingyun Zhao
Patrick Bron
Umar F. Shahul Hameed
Stefan T. Arold
Bilal M. Qureshi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.890390

6,257 views
9 citations

Original Research

Published on 15 Jun 2022

Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function

in Structural Biology

Sofia S. Mariasina
Chi-Fon Chang
Tsimafei L. Navalayeu
Anastasia A. Chugunova
Sergey V. Efimov
Viktor G. Zgoda
Vasily A. Ivlev
Olga A. Dontsova
Petr V. Sergiev
Vladimir I. Polshakov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.865743

4,024 views
6 citations

501 articles

articles

Editorial: Tailored Modulation of Interactions Between Biomolecules: Fundamentals and Applications

An Extended C-Terminus, the Possible Culprit for Differential Regulation of 5-Aminolevulinate Synthase Isoforms

The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli

Editorial: Nucleic Acid Polymerases: The Two-Metal-Ion Mechanism and Beyond

Developing Graphene Grids for Cryoelectron Microscopy

Structural Requirements and Plasticity of Receptor-Binding Domain in Human Coronavirus Spike

Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C

Impact of Bioconjugation on Structure and Function of Antibodies for Use in Immunoassay by Hydrogen-Deuterium Exchange Mass Spectrometry

Quantitative Cryo-Electron Tomography

Accelerated 2D Classification With ISAC Using GPUs

Impact of Formulation Choices on the Freeze-Drying of an Interleukin-6 Reference Material

Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design

Photoactivation of a Mechanosensitive Channel

Wild-Type α-Synuclein and Variants Occur in Different Disordered Dimers and Pre-Fibrillar Conformations in Early Stage of Aggregation

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7

Human Claudin-7 cis-Interactions Are Not Crucial for Membrane-Membrane (Trans-) Interactions

A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies

Editorial: Integrative Structural Biology of Proteins and Macromolecular Assemblies: Bridging Experiments and Simulations

Recent Technical Advances in Sample Preparation for Single-Particle Cryo-EM

Biophysical Screening Pipeline for Cryo-EM Grid Preparation of Membrane Proteins

Approaches to Using the Chameleon: Robust, Automated, Fast-Plunge cryoEM Specimen Preparation

OOP-ESEEM Spectroscopy: Accuracies of Distances of Spin-Correlated Radical Pairs in Biomolecules

Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids

Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function