Frontiers in Molecular Biosciences

Review

Published on 23 Oct 2025

Biophysical insights into the molecular mechanisms of beta amyloid aggregation and its toxic effects in Alzheimer’s disease

Soghra Bagheri
Luciano Saso

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1704653

2,786 views

Original Research

Published on 22 Oct 2025

Identification of mitochondrial related gene characteristics and potential molecular mechanism of acute otitis media

Dingjing Zi
Xiaoyong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1642269

1,521 views

Original Research

Published on 22 Oct 2025

Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma

Xin Wang
Haixiang Zhang
Jinping Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1654064

1,145 views

Original Research

Published on 21 Oct 2025

Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution

Toru Ishibashi
Enjuro Harunari
Genki Ishihara
Tetsushi Niiyama
Mami Noda-Urata
Nobuaki Komori

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1680812

2,143 views

Original Research

Published on 21 Oct 2025

Unraveling metabolic reprogramming in ΔhnoxParacoccus denitrificans: a time-resolved metabolomics and AI-Powered proteome modeling approach

Md Shariful Islam
Aishat Alatishe
William Bahureksa
Erik Yukl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1679650

2,055 views

Review

Published on 21 Oct 2025

Phenolic acids in fermented foods: microbial biotransformation, antioxidant mechanisms, and functional health implications

Anand Kumar
S. Saranyadevi
Selva Kumar Thirumalaisamy
Tharindu Trishan Dapana Durage
Swapnil Ganesh Jaiswal
Digambar Kavitake
Shuai Wei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1678673

4,331 views
6 citations

Original Research

Published on 21 Oct 2025

Untargeted metabolomics unveils metabolic biomarkers in HFpEF

Dongqin Duan
Muyashaer Abudurexiti
Refukaiti Abuduhalike
Salamaiti Aimaier
Ailiman Mahemuti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1673430

2,498 views
1 citation

Review

Published on 21 Oct 2025

Mechanosensitive channel Piezo1 in calcium dynamics: structure, function, and emerging therapeutic strategies

Yu Liu
Yu-Qiu Xu
Yu-Yin Long
Hui Xiao
Yu-Ying Ma
Yong-Wang Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1693456

6,209 views
4 citations

Original Research

Published on 20 Oct 2025

Specificity of mRNA binding to proteins within the NMD machinery is influenced in cancer

Umesh Kalathiya
Monikaben Padariya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1606190

8,558 views

Review

Published on 17 Oct 2025

The janus-faced biology of GPNMB: from tissue homeostasis to cancer pathogenesis

Cheng Long
Li Qin Yun
Ma Dai Yuan
Imad Ibrahim Ali Al-Sultan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1664764

2,864 views
1 citation

Review

Published on 17 Oct 2025

Recent research advances in RNA m5C methylation modification in liver diseases

Wenjuan Chen
Lifan Zhang
Xinyu Gu
Yafeng Liu
Shujun Zhang
Xinjun Hu
Penghui Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1657502

1,974 views

Original Research

Published on 16 Oct 2025

Impact of endurance training on mitochondrial H2O2 production and NRF2 levels in different rat organs

Lukasz Galganski
Krzysztof Wojcicki
Wieslawa Jarmuszkiewicz
Jerzy A. Zoladz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1653162

1,862 views
1 citation

Review

Published on 15 Oct 2025

Advances of nanopore direct sequencing technology and bioinformatics analysis for cell-free DNA detection and its clinical applications in cancer liquid biopsy

Jiaxin Tan
Zetong Wu
Yunya Zhu
Biyuan Miao
Daofeng Xu
Jia Gu
Maohong Hu
Pingping Xu
Shaogui Wan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1662587

3,224 views
1 citation

Original Research

Published on 15 Oct 2025

Mapping of chromatin architecture and enhancer-promoter interactions in the cochlea

Tuba Ege
Celia R. Bloom
Mi Zhou
Huizhan Liu
Litao Tao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683964

2,807 views
1 citation

Original Research

Published on 15 Oct 2025

Comprehensive analyses of single-cell and bulk RNA-seq reveal the biological and prognostic roles of BMP4 in pancreatic adenocarcinoma

Ao Wang
Xinglong Shen
Shan Lu
Chao Bi
Yang Cao
Yunfeng Liu
Meng Li
Yun Zhao
Huaizhang Jin
Xiaopeng Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1686938

1,488 views

Review

Published on 15 Oct 2025

Mechanistic insights into cisplatin-induced ototoxicity: the central role of transient receptor potential channels

Man Yu
Juanjuan Li
Xianhai Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1694131

1,371 views

Review

Published on 15 Oct 2025

Animal models in tuberculosis metabolomics: a systematic review of current evidence and the road to translational relevance

Rochelle Caudron
Ilse Du Preez
Laneke Luies
Monique Opperman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1688882

2,132 views

Original Research

Published on 14 Oct 2025

Construction of a diagnostic model and identification of effect genes for diabetic kidney disease with concurrent vascular calcification based on bioinformatics and multiple machine learning approaches

Lili Huang
Wenjing Wu
Shenhui Lv
Danfang Deng
Xiaoqin Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1609307

2,739 views
2 citations

Original Research

Published on 14 Oct 2025

ITRAQ and PRM-based quantitative saliva proteomics in gastric cancer: biomarker discovery

Zhanyan Liu
Jieren Liu
Zaid Chachar
Jimao Mo
Haoran Chi
Runtao Wen
Kaixin Luo
Lei Huang
Guanlin Li
Chenhao Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1640508

2,105 views
2 citations

Original Research

Published on 13 Oct 2025

Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system

Josiah T. Wagner
John T. Welle
Isabelle A. Lucas Beckett
Kate R. Emery
Benjamin A. Cosgrove
Krzysztof Olszewski
Nick Wagner
Tucker C. Bower
Li Chi Yuan
Eric M. Shull

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1669085

2,427 views

Original Research

Published on 13 Oct 2025

Exploring molecular characteristics and interactions of blood stasis syndrome in ischemic heart failure by integrated multi-omics

Aolong Wang
Jingjing Wei
Lijie Qiao
Xingyuan Li
Ming Li
Xinfeng Zhu
Yilin Zhang
Qifei Zhao
Rui Yu
Bin Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1627849

2,156 views

Original Research

Published on 13 Oct 2025

Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design

Douglas Lin
Michael Martin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595363

2,306 views
1 citation

Review

Published on 13 Oct 2025

ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs

Rachel E. Turn
Joel Bryan Dacks
Eric M. Rosenberg
Olivier Soubias
John K. Northup
Paul A. Randazzo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1668286

2,132 views

Original Research

Published on 13 Oct 2025

Distinct effects of progesterone and cholesterol on lipid membranes: insights from biophysical experiments and molecular dynamics simulations

Anna Lągowska
Emilia Krok
Maria Domanska
Piotr Setny
Lukasz Piatkowski
Hanna Orlikowska-Rzeznik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1662811

2,162 views

5,866 Publications

volumes

Volume 12 - 2025

Biophysical insights into the molecular mechanisms of beta amyloid aggregation and its toxic effects in Alzheimer’s disease

Identification of mitochondrial related gene characteristics and potential molecular mechanism of acute otitis media

Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma

Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution

Unraveling metabolic reprogramming in ΔhnoxParacoccus denitrificans: a time-resolved metabolomics and AI-Powered proteome modeling approach

Phenolic acids in fermented foods: microbial biotransformation, antioxidant mechanisms, and functional health implications

Untargeted metabolomics unveils metabolic biomarkers in HFpEF

Mechanosensitive channel Piezo1 in calcium dynamics: structure, function, and emerging therapeutic strategies

Specificity of mRNA binding to proteins within the NMD machinery is influenced in cancer

The janus-faced biology of GPNMB: from tissue homeostasis to cancer pathogenesis

Recent research advances in RNA m5C methylation modification in liver diseases

Impact of endurance training on mitochondrial H2O2 production and NRF2 levels in different rat organs

Advances of nanopore direct sequencing technology and bioinformatics analysis for cell-free DNA detection and its clinical applications in cancer liquid biopsy

Mapping of chromatin architecture and enhancer-promoter interactions in the cochlea

Comprehensive analyses of single-cell and bulk RNA-seq reveal the biological and prognostic roles of BMP4 in pancreatic adenocarcinoma

Mechanistic insights into cisplatin-induced ototoxicity: the central role of transient receptor potential channels

Animal models in tuberculosis metabolomics: a systematic review of current evidence and the road to translational relevance

Construction of a diagnostic model and identification of effect genes for diabetic kidney disease with concurrent vascular calcification based on bioinformatics and multiple machine learning approaches

ITRAQ and PRM-based quantitative saliva proteomics in gastric cancer: biomarker discovery

Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system

Exploring molecular characteristics and interactions of blood stasis syndrome in ischemic heart failure by integrated multi-omics

Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design

ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs

Distinct effects of progesterone and cholesterol on lipid membranes: insights from biophysical experiments and molecular dynamics simulations