Frontiers in Molecular Biosciences

Original Research

Published on 18 Jul 2025

Dynamic contrast-enhanced MRI-based radiomics model of intra-tumoral kinetic heterogeneity for predicting breast cancer molecular subtypes

Yue Cheng
Ran Ren
Yu Xu
Shaofeng Duan
Jilei Zhang
Zhongyuan Bao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1635296

1,988 views
1 citation

Review

Published on 17 Jul 2025

The role of epigenetics in pulmonary fibrosis: recent advances in mechanistic insights and therapeutic implications

Jingru Huang
Jianfeng Qin
Yuguang Zhu
Ao Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1647300

2,912 views
1 citation

Original Research

Published on 17 Jul 2025

Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics

Xi Chen
Elizabeth A. Grimm
Yong Qin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1637230

1,666 views

Original Research

Published on 17 Jul 2025

Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect

Charlotte de Ceuninck van Capelle
Leo Luo
Alexander Leitner
Stefan A. Tschanz
Philipp Latzin
Sebastian Ott
Tobias Herren
Loretta Müller
Takashi Ishikawa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593810

2,661 views
1 citation

Review

Published on 16 Jul 2025

An overview of current research on the modulation of NLRP3 inflammasome by traditional Chinese medicine to combat acute pancreatitis

Xiongjie He
Jia Xia
Qi Chen
Zhaozhao Huang
Juanjuan Lu
Yisong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1634132

2,263 views

Original Research

Published on 16 Jul 2025

Identification and validation of integrated stress-response-related genes as biomarkers for age-related macular degeneration

Jingyi Niu
Ling Jin
Yijun Hu
Yiting Wang
Xiaoning Hao
Wenwen Geng
Ruirui Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583237

1,980 views
1 citation

Brief Research Report

Published on 15 Jul 2025

An integrated approach for analyzing spatially resolved multi-omics datasets from the same tissue section

Thao Tran
Felicia Wee
Craig Ryan Joseph
Wanqiu Zhang
Jeffrey Chun Tatt Lim
Zhen Wei Neo
Li Yen Chong
Francis Hong Xin Yap
Nathan Heath Patterson
Marc Claesen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614288

6,414 views
1 citation

Original Research

Published on 15 Jul 2025

Expression and clinical significance of S100A8/9 in adults with secondary phagocytic lymphohistiocytosis

Ziwei Fang
Xin Gao
Limin Duan
Jujuan Wang
Tian Tian
Ji Xu
Yongqian Shu
Guangli Yin
Hongxia Qiu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607352

1,337 views
1 citation

Original Research

Published on 14 Jul 2025

Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures

Rongyue Ma
Huangruici Zhang
Weijie Wang
Changping Yu
Guohang Xiong
Qing Li
Yan Wang
Li Zhou
Yu Zhang
Min Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567064

2,113 views

Original Research

Published on 14 Jul 2025

Neuroprotective effect of silymarin-loaded nanoliposomes against monosodium glutamate-induced cerebellar motor deficit and Purkinje cell damage in experimental rats via PI3K/AKT pathway activation

Medhat Taha
Ahmed Alzahrani
Omer Abdelbagi
Rehab M. Bagadood
Naeem F. Qusty
Rami Obaid
Mohammad El-Nablaway
Tourki A. S. Baokbah

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621240

1,774 views
1 citation

Editorial

Published on 14 Jul 2025

Editorial: Ironome: a still untapped frontier

Gloria C. Ferreira
Vladimir N. Uversky
Zoubida Karim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1651154

2,037 views

Original Research

Published on 11 Jul 2025

Targeting USP42 induces DNA damage and inhibits cell growth in prostate cancer

Yinghao Zhou
Chenchen Chen
Yibo Meng
Jianchao Ge
Shengkui Meng
Xillong Wang
Yaozong Xu
Guowei Shi
Wandong Yu
Xuetao Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1646331

1,867 views

Original Research

Published on 11 Jul 2025

Integrated network pharmacology and in vivo experiments to reveal the anti-inflammatory mechanism of Qinghuo Rougan Formula in uveitis

Changying Jing
Yaqi Sun
Hongsheng Bi
Junguo Guo
Cong Ren
Jike Song
Beibei Wang
Qingmei Tian
Dadong Guo
Pengjuan He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1632027

2,406 views

Original Research

Published on 11 Jul 2025

Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza

Zhaoyuan Gong
Qianzi Che
Mingzhi Hu
Tian Song
Lin Chen
Haili Zhang
Ning Liang
Huizhen Li
Guozhen Zhao
Lijiao Yan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1637980

2,968 views

Original Research

Published on 11 Jul 2025

Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery

William A. Fountain
Stefano Donega
Nirad Banskota
Ruin Moaddel
Mona Patel
Linda Zukley
Sarah Church
Katie Bustin
Josephine M. Egan
Jeremy Walston

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1613238

2,203 views

Original Research

Published on 11 Jul 2025

ER stress-driven unfolded protein response fuels aging-related tumor aggressiveness in gliomas

Xiaodong Shao
Shaolei Guo
Jia Yang
Junjie Dai
Kaihua Cao
Xia Cai
Tianshi Song
Shun Yao
Umar Raza
Kun Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1640038

2,010 views

Review

Published on 11 Jul 2025

Review of research progress in sepsis-associated acute kidney injury

Wanning Nian
Weichen Tao
Haiyi Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1603392

4,808 views
2 citations

Review

Published on 10 Jul 2025

Subtle concentration changes in zinc hold the key to fibrillation of α-synuclein: an updated insight on the micronutrient’s role in prevention of neurodegenerative disorders

Samudra Prosad Banik
Debasis Bagchi
Pradipta Banerjee
Sanjoy Chakraborty
Manashi Bagchi
Chaitali Bose
Debasmita De
Sreemoyee Saha
Sudipta Chakraborty

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1603364

3,755 views
2 citations

Original Research

Published on 10 Jul 2025

An automatic laryngoscopic image segmentation system based on SAM prompt engineering: from glottis annotation to vocal fold segmentation

Yucong Zhang
Yuchen Song
Juan Liu
Ming Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1616271

1,707 views
1 citation

Original Research

Published on 10 Jul 2025

Value of the 14-gene molecular assay in efficacy assessment of neoadjuvant chemoimmunotherapy for non-small cell lung cancer

Xuyan Lan
Xiaoyu Sun
Ruiqi Chen
Lihuan Zhu
Xiaojie Pan
Tianxing Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1619139

1,763 views

Original Research

Published on 10 Jul 2025

Structural bioinformatics and gene expression analysis of maturase K from Lavandula angustifolia (lavender)

Dafeng Liu
Na Li
Daoqi Song
Zhenming Lv

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1628118

1,689 views
2 citations

Review

Published on 09 Jul 2025

Functional metabolomics: unlocking the role of small molecular metabolites

Hetao Chen
Jiao Kong
Peipei Du
Qian Wang
Tao Jiang
Xixi Hou
Tingting Feng
Jiajia Duan
Chuanxin Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542100

2,711 views
2 citations

Original Research

Published on 09 Jul 2025

A comprehensive characterization of metabolic signatures—hypoxia, glycolysis, and lactylation—in non-healing diabetic foot ulcers

Bo Hu
Xuan Li
Yunfeng Li
Shengnan Chai
Mei Jin
Long Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593390

4,215 views
2 citations

Editorial

Published on 09 Jul 2025

Editorial: Molecular chaperones and polyamines in disease

Stanley Makumire
Graham Chakafana
Xolani H. Makhoba

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1658176

1,048 views

547 Publications

volumes

Dynamic contrast-enhanced MRI-based radiomics model of intra-tumoral kinetic heterogeneity for predicting breast cancer molecular subtypes

The role of epigenetics in pulmonary fibrosis: recent advances in mechanistic insights and therapeutic implications

Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics

Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect

An overview of current research on the modulation of NLRP3 inflammasome by traditional Chinese medicine to combat acute pancreatitis

Identification and validation of integrated stress-response-related genes as biomarkers for age-related macular degeneration

An integrated approach for analyzing spatially resolved multi-omics datasets from the same tissue section

Expression and clinical significance of S100A8/9 in adults with secondary phagocytic lymphohistiocytosis

Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures

Neuroprotective effect of silymarin-loaded nanoliposomes against monosodium glutamate-induced cerebellar motor deficit and Purkinje cell damage in experimental rats via PI3K/AKT pathway activation

Editorial: Ironome: a still untapped frontier

Targeting USP42 induces DNA damage and inhibits cell growth in prostate cancer

Integrated network pharmacology and in vivo experiments to reveal the anti-inflammatory mechanism of Qinghuo Rougan Formula in uveitis

Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza

Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery

ER stress-driven unfolded protein response fuels aging-related tumor aggressiveness in gliomas

Review of research progress in sepsis-associated acute kidney injury

Subtle concentration changes in zinc hold the key to fibrillation of α-synuclein: an updated insight on the micronutrient’s role in prevention of neurodegenerative disorders

An automatic laryngoscopic image segmentation system based on SAM prompt engineering: from glottis annotation to vocal fold segmentation

Value of the 14-gene molecular assay in efficacy assessment of neoadjuvant chemoimmunotherapy for non-small cell lung cancer

Structural bioinformatics and gene expression analysis of maturase K from Lavandula angustifolia (lavender)

Functional metabolomics: unlocking the role of small molecular metabolites

A comprehensive characterization of metabolic signatures—hypoxia, glycolysis, and lactylation—in non-healing diabetic foot ulcers

Editorial: Molecular chaperones and polyamines in disease