Frontiers in Molecular Biosciences

Original Research

Published on 09 Jul 2025

Raider of the lost N-glycans – Localizing rare and frequently overlooked IgG N-glycans with sulfation or bisecting LacNAc

Robert Burock
Léa Chuzel
Thilo Kähne
Udo Reichl
Erdmann Rapp
René Hennig

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593708

3,438 views
1 citation

Original Research

Published on 08 Jul 2025

Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics

Ji-Peng Liu
Long-Teng Tu
Ke-Zhen Yang
Yin-Yin Li
Yu Gong
Bing-Xuan Han
Chuan Liu
Tian-Qi Xia
Yu Liu
Xiao-Min Hao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1619356

2,382 views

Original Research

Published on 07 Jul 2025

Gene expression profiling of human umbilical vein endothelial cells overexpressing CELF2 as diagnostic targets in diabetes-induced erectile dysfunction

Daniyaer Nuerdebieke
Lizhong Yao
Lange Guo
Jiuzhi Li
Hongliang Jia
Yukui Nan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1596534

1,446 views

Original Research

Published on 07 Jul 2025

Sustainable synthesis of zinc oxide nanoparticles from Persicaria lapathifolia: versatile anticancer and antibacterial applications

Essam Nageh Sholkamy
Mohamed A. A. Abdelhamid
Hadjer Rebai
Ananth Sivapunniyam
Mi-Ran Ki
Seung Pil Pack
Hazim O. Khalifa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1601811

2,009 views
1 citation

Original Research

Published on 04 Jul 2025

Exploring potential therapeutic targets for colorectal tumors based on whole genome sequencing of colorectal tumors and paracancerous tissues

Yufan Sheng
Sen Niu
Da Li
Chunyuan Meng
Tong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1605117

2,041 views

Original Research

Published on 03 Jul 2025

A nomogram model based on tumor necrosis factor-like ligand 1A(TL1A) and death receptor-3(DR3) promoter methylation for predicting 90-day prognosis in patients with HBV-associated acute-on-chronic liver failure

Xue-Fei Wei
Feng Zhang
Han-Xu Zhu
Zhe-Zhe Tian
Miao-Miao Xu
Yu-Chen Fan
Kai Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614311

2,078 views

Hypothesis and Theory

Published on 02 Jul 2025

Dinucleotide codon substitutions as a signature of diversifying selection in Mycobacterium tuberculosis

Danila Zimenkov
Anastasia Ushtanit

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1511372

2,348 views

Original Research

Published on 01 Jul 2025

Clinicopathologic and proteomic characteristics of low-grade undifferentiated spindle cell sarcoma

Yani Wei
Hongjun Li
Shujin He
Min Li
Yongyu Chen
Huijuan Shi
Anjia Han

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1591644

2,043 views

Mini Review

Published on 30 Jun 2025

Estrogen, menopause, and Alzheimer’s disease: understanding the link to cognitive decline in women

Nicholas Mervosh
Gayatri Devi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1634302

11,027 views
7 citations

Original Research

Published on 30 Jun 2025

Patient-derived gastric cancer organoids model heterogeneity and stroma-mediated chemoresistance in poorly cohesive carcinoma

Yi Yin
Shuhong Zeng
Hui Zhang
Shuangshuang Wang
Fei Ke
Qiang Rui
Jinyong Zhou
Yuwen Zhuang
Weixing Shen
Jun Qian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1631168

3,132 views
1 citation

Review

Published on 30 Jun 2025

Emerging biomarkers in amyotrophic lateral sclerosis: from pathogenesis to clinical applications

Farah Anjum
Maha Bakhuraysah
Abdulaziz Alsharif
Taj Mohammad
Anas Shamsi
Md. Imtaiyaz Hassan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1608853

7,010 views

Original Research

Published on 30 Jun 2025

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

Shengsheng Li
Shenglan Qi
Rongsheng Li
Fangming Yang
Zhenyi Niu
Wei Liu
Suping Ma
Zhun Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614341

2,994 views
1 citation

Original Research

Published on 27 Jun 2025

Recognition of pivotal immune genes NR1H4 and IL4R as diagnostic biomarkers in distinguishing ovarian clear cell cancer from high-grade serous cancer

Yumin Ke
Meili Liang
Zhimei Zhou
Yajing Xie
Li Huang
Liying Sheng
Yueli Wang
Xinyan Zhou
Zhuna Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1600808

1,656 views

Original Research

Published on 27 Jun 2025

Inhibition of USP11 attenuates sepsis-associated acute kidney injury by downregulating TGFBR2/Smad3 signaling

Lu Wang
Wen Tang
Long Jiang
Daquan Zhang
Zhigao Wang
Rennan Guo
Jingjing Wang
Dong Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1571593

1,704 views

Original Research

Published on 26 Jun 2025

Identification of diagnostic hub genes related to energy metabolism in idiopathic pulmonary fibrosis

S. Zhao
B. C. Sun
N. Liu
R. Huo
L. S. Liu
J. P. Wang
C. Y. Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1596364

3,337 views
1 citation

Original Research

Published on 26 Jun 2025

Exploring the association between circadian rhythms and osteoporosis: new diagnostic and therapeutic targets identified via machine learning

Jian Du
Tian Zhou
Ran Meng
Wei Zhang
Jin Zhou
Wei Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614221

3,207 views

Review

Published on 26 Jun 2025

Hormonal modulation, mitochondria and Alzheimer’s prevention: the role of GLP-1 agonists and estrogens

Fernando Lizcano
Daniela Sanabria
Eliana Aviles

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1622186

4,336 views
2 citations

Mini Review

Published on 25 Jun 2025

Kinase-dependent regulation of ciliary protein transport and its implications for therapy

Taro Chaya
Yuri Ayano
Takahisa Furukawa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1638737

2,697 views

Editorial

Published on 24 Jun 2025

Editorial: Methodological advancements and improvements in structural biology

Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1625111

1,694 views

Mini Review

Published on 24 Jun 2025

Protective role of dietary zinc on DNA damage, oxidative stress, and metal toxicity

Carmen P. Wong
Laura M. Beaver
Emily Ho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1618318

2,884 views
2 citations

Original Research

Published on 24 Jun 2025

Identification of hub genes in myocardial infarction by bioinformatics and machine learning: insights into inflammation and immune regulation

Juan Yang
Xiang Li
Li Ma
Jun Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607096

2,920 views
2 citations

Original Research

Published on 23 Jun 2025

Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer

Jian Zhang
Xiaosong Fan
Xu Xu
Yichao Han
Weixing Yu
Bicheng Yang
Yanling Chen
Shaolin Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1602700

2,697 views

Original Research

Published on 20 Jun 2025

Developing a molecular diagnostic model for heatstroke-induced coagulopathy: a proteomics and metabolomics approach

Qingbo Zeng
Qingwei Lin
Longping He
Lincui Zhong
Ye Zhou
Xingping Deng
Nianqing Zhang
Qing Song
Jingchun Song

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1616073

2,355 views

Original Research

Published on 19 Jun 2025

Comprehensive analysis of phagocytosis regulatory genes in bladder cancer: implications for prognosis and immunotherapy

Xueming Ma
Dongnuan Yao
Weitao Yu
Gongping Wu
Chengwei Fan
Junqiang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1608519

1,993 views

547 Publications

volumes

Raider of the lost N-glycans – Localizing rare and frequently overlooked IgG N-glycans with sulfation or bisecting LacNAc

Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics

Gene expression profiling of human umbilical vein endothelial cells overexpressing CELF2 as diagnostic targets in diabetes-induced erectile dysfunction

Sustainable synthesis of zinc oxide nanoparticles from Persicaria lapathifolia: versatile anticancer and antibacterial applications

Exploring potential therapeutic targets for colorectal tumors based on whole genome sequencing of colorectal tumors and paracancerous tissues

A nomogram model based on tumor necrosis factor-like ligand 1A(TL1A) and death receptor-3(DR3) promoter methylation for predicting 90-day prognosis in patients with HBV-associated acute-on-chronic liver failure

Dinucleotide codon substitutions as a signature of diversifying selection in Mycobacterium tuberculosis

Clinicopathologic and proteomic characteristics of low-grade undifferentiated spindle cell sarcoma

Estrogen, menopause, and Alzheimer’s disease: understanding the link to cognitive decline in women

Patient-derived gastric cancer organoids model heterogeneity and stroma-mediated chemoresistance in poorly cohesive carcinoma

Emerging biomarkers in amyotrophic lateral sclerosis: from pathogenesis to clinical applications

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

Recognition of pivotal immune genes NR1H4 and IL4R as diagnostic biomarkers in distinguishing ovarian clear cell cancer from high-grade serous cancer

Inhibition of USP11 attenuates sepsis-associated acute kidney injury by downregulating TGFBR2/Smad3 signaling

Identification of diagnostic hub genes related to energy metabolism in idiopathic pulmonary fibrosis

Exploring the association between circadian rhythms and osteoporosis: new diagnostic and therapeutic targets identified via machine learning

Hormonal modulation, mitochondria and Alzheimer’s prevention: the role of GLP-1 agonists and estrogens

Kinase-dependent regulation of ciliary protein transport and its implications for therapy

Editorial: Methodological advancements and improvements in structural biology

Protective role of dietary zinc on DNA damage, oxidative stress, and metal toxicity

Identification of hub genes in myocardial infarction by bioinformatics and machine learning: insights into inflammation and immune regulation

Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer

Developing a molecular diagnostic model for heatstroke-induced coagulopathy: a proteomics and metabolomics approach

Comprehensive analysis of phagocytosis regulatory genes in bladder cancer: implications for prognosis and immunotherapy