Frontiers in Molecular Biosciences

Original Research

Published on 26 May 2025

A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer

Yinmeng Zhang
Jiawei Fan
Jiahui Zhao
He Zhu
Yan Xia
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615533

3,780 views

Review

Published on 26 May 2025

Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

Chandra Kanta Bhusal
Shweta Sinha
Davinder Kaur
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573618

5,756 views
10 citations

Review

Published on 22 May 2025

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

Almohanad A. Alkayyal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615393

2,679 views

Editorial

Published on 22 May 2025

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

Lin Zhang
Weiye Qian
Qingyu Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620512

1,636 views

Editorial

Published on 22 May 2025

Editorial: Emerging advancements in the carbonic anhydrase field

Simona Maria Monti
Vincenzo Alterio
Seppo Parkkila
Claudiu T. Supuran
Giuseppina De Simone

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1624394

2,029 views

Review

Published on 21 May 2025

A comprehensive review of diagnostic approaches for hepatitis D

Wen-Hui Liu
Jia-Yue Cui
Miao Yu
Xiao-Dong Shi
Yi-Lin Che
Chu-Yan Wang
Xiu-Mei Chi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598784

4,794 views
2 citations

Review

Published on 20 May 2025

Regulating the expression of exercise-induced micro-RNAs and long non-coding RNAs: implications for controlling cardiovascular diseases and heart failure

Guobiao Yang
Wanying Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1587124

2,971 views
4 citations

Correction

Published on 19 May 2025

Corrigendum: Computational analysis of the structural-functional dynamics of a Co-receptor proteoglycan

Francesco Tavanti
Giorgia Brancolini
Roberto Perris

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1612818

1,347 views

Original Research

Published on 19 May 2025

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

Etianne Martini Sasso
Natalie Eaton-Fitch
Peter Smith
Katsuhiko Muraki
Sonya Marshall-Gradisnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1582967

26,554 views
4 citations

Original Research

Published on 16 May 2025

Effect of antagomir-22-3p treatment on skeletal muscle growth in intrauterine growth-restricted lambs

S. K. Duckett
M. A. Greene
A. N. S. Udoka
R. R. Powell
T. F. Bruce
J. L. Klotz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547182

2,679 views
2 citations

Original Research

Published on 16 May 2025

Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

Junyan Wang
Panpan Sun
Fan Zhang
Yu Xu
Shenghu Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1592888

3,643 views

Original Research

Published on 16 May 2025

Integrating network pharmacology and experimental validation to reveal the anti-growth mechanism of panaxadiol against glioblastoma via calcium signaling

Guobin Qiu
Zhiyong Wu
Dunhui Yang
Luqiu Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598413

2,262 views

Brief Research Report

Published on 16 May 2025

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

Hao Chen
Yang Zhong
Rongjie Feng
Xingyu Zhu
Kang Xu
Mingjie Kuang
Wei Chong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556736

3,193 views
1 citation

Original Research

Published on 16 May 2025

Serotoninergic modulation in the brainstem and hypothalamus of female overnourished rats: impact on mitochondrial markers, oxidative stress and BDNF mRNA levels

Thyago de Oliveira Rodrigues
Osmar Henrique dos Santos Júnior
Maria Daniele Teixeira Beltrão de Lemos
Matheus Santos de Sousa Fernandes
Fatma Hilal Yagin
Burak Yagin
Samarjit Das
Abdullah F. Alghannam
Pablo Prieto-González
Claudia J. Lagranha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1564061

1,844 views

Original Research

Published on 15 May 2025

Broad-spectrum coronavirus inhibitors discovered by modeling viral fusion dynamics

Charles B. Reilly
Joel Moore
Shanda Lightbown
Austin Paul
Sylvie G. Bernier
Kenneth E. Carlson
Donald E. Ingber

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1575747

6,332 views
2 citations

Original Research

Published on 15 May 2025

Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning

Chenxuyu Zhang
Zheng Luo
Liang Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554304

4,359 views
1 citation

Original Research

Published on 15 May 2025

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

Yinmeng Zhang
He Zhu
Jiawei Fan
Jiahui Zhao
Yan Xia
Nan Zhang
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599141

4,145 views

Editorial

Published on 15 May 2025

Editorial: Advancements and future challenges in molecular diagnostics and therapeutics

Matteo Becatti
Masoud Mozafari
Roberta Risoluti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620909

2,050 views
1 citation

Original Research

Published on 14 May 2025

Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

Roberta Marongiu
Jimcy Platholi
Laibaik Park
Fangmin Yu
Garrett Sommer
Clara Woods
Teresa A. Milner
Michael J. Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597130

4,220 views
3 citations

Original Research

Published on 14 May 2025

A LODDS-based nomogram for overall and cancer-specific survival in stage III-IV gastric signet ring cell carcinoma

Cenzhu Wang
Ying Fang
Yuhan Zhang
Shuhan Feng
Rui Hou
Hanfang Fan
Zeyu Wang
Lei Liu
Junli Ding
Junying Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1600626

2,492 views
1 citation

Methods

Published on 13 May 2025

Thioflavin T in-gel staining for ex vivo analysis of cardiac amyloid

Joseph Oldam
Irina Tchernyshyov
Jennifer Van Eyk
Juan Troncoso
Charles G. Glabe
Giulio Agnetti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1505250

2,509 views

Review

Published on 13 May 2025

Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities

Ziling Pang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578693

2,625 views
3 citations

Original Research

Published on 12 May 2025

Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head

Ming-gang Guo
Chen-fei Yang
Fa Yuan
Tao Yang
Ping-yuan Luo
Yu-bai He
Shuan Yang
Feng Chen
Wei Li
Zhi-wei Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578755

3,845 views

Original Research

Published on 12 May 2025

Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data

Lian Duan
Mahshad Hashemi
Alioune Ngom
Luis Rueda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547231

3,226 views
2 citations

5,873 Publications

volumes

Volume 12 - 2025

A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer

Unravelling drug resistance in leishmaniasis: genomic adaptations and emerging therapies

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

Editorial: Emerging advancements in the carbonic anhydrase field

A comprehensive review of diagnostic approaches for hepatitis D

Regulating the expression of exercise-induced micro-RNAs and long non-coding RNAs: implications for controlling cardiovascular diseases and heart failure

Corrigendum: Computational analysis of the structural-functional dynamics of a Co-receptor proteoglycan

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

Effect of antagomir-22-3p treatment on skeletal muscle growth in intrauterine growth-restricted lambs

Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

Integrating network pharmacology and experimental validation to reveal the anti-growth mechanism of panaxadiol against glioblastoma via calcium signaling

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

Serotoninergic modulation in the brainstem and hypothalamus of female overnourished rats: impact on mitochondrial markers, oxidative stress and BDNF mRNA levels

Broad-spectrum coronavirus inhibitors discovered by modeling viral fusion dynamics

Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

Editorial: Advancements and future challenges in molecular diagnostics and therapeutics

Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

A LODDS-based nomogram for overall and cancer-specific survival in stage III-IV gastric signet ring cell carcinoma

Thioflavin T in-gel staining for ex vivo analysis of cardiac amyloid

Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities

Bioinformatics and experimental validation of ferroptosis-related genes in steroid-induced osteonecrosis of the femoral head

Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data