Frontiers in Molecular Medicine

Editorial

Published on 05 May 2026

Editorial: Targeted cancer therapy through metabolic pathways

in Molecular Medicine and Cancer Treatment

Prasanna Srinivasan Ramalingam
Md Sadique Hussain
Shreyas Ramchandra Gaikwad
Sivakumar Arumugam

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1842647

510 views

Mini Review

Published on 29 Apr 2026

Mapping the future of medicine through digital twins

in Bioinformatics and Artificial Intelligence for Molecular Medicine

Frank Emmert-Streib
Shailesh Tripathi
Olli Yli-Harja

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1840371

612 views

Review

Published on 28 Apr 2026

Sirtuin 1 is a key molecular link between cellular senescence and heart failure

in Molecular Medicine for Cardiology

Jan Krekora
Jarosław Drożdż
Janusz Blasiak

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1818104

568 views

Original Research

Published on 15 Apr 2026

Molecular mechanisms underlying psoriasis and depression: an integrated analysis using mendelian randomization, transcriptomics, and single-cell sequencing

in Molecular Microbes, Disease and Mechanisms of Immune Response

Baojun De
Wenfeng Bao
Nagongbilige Hea
Jun Fang

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1770665

654 views

Original Research

Accepted on 08 Apr 2026

Blood biomarkers and atrial remodeling in patients at risk of atrial fibrillation

in Molecular Medicine for Cardiology

Filip Loncaric
Ilana Forado Benatar
Maria Mimbrero Guillamon
Loredana Nunno
Rafael Jimenez-Arjona
Laia Tirapu
Sílvia Montserrat
Laura Sanchis
Adelina Doltra
Bart Bijnens

Frontiers in Molecular Medicine

325 views

Original Research

Published on 23 Feb 2026

HIF1α reinforces PPARγ-dependent metabolic rechanneling to support lipid accumulation in adipocytes

in Molecular Microbes, Disease and Mechanisms of Immune Response

Chaonan Zhu
Meiqian Wu
Minh Duc Pham
Yue Wang
Arka Provo Das
Yijie Mao
Peter Mirtschink
Ting Yuan
Jaya Krishnan

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1716464

718 views

Original Research

Published on 12 Feb 2026

CD19 exon 2 skipping is a potential prognostic correlate of anti-CD19 CAR-T therapy relapse

in Molecular Microbes, Disease and Mechanisms of Immune Response

Søren Helweg Dam
Giorgia Moranzoni
Magnus Haraldson Høie
Signe Modvig
Karin A. W. Wadt
Bodil Als-Nielsen
Kjeld Schmiegelow
Kristoffer Vitting-Seerup
Mike Bogetofte Barnkob
Lars Rønn Olsen

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2026.1763390

764 views

Original Research

Published on 04 Dec 2025

Association of specific HLA alleles in patients with interstitial cystitis suggesting autoimmunity

in Molecular Microbes, Disease and Mechanisms of Immune Response

Inna Tabansky Stern
Jiayao Wang
Robert M. Moldwin
Jason M. Kim
Jason H. Singh
Derek C. Tran
Souhel Najjar
Melis Akinci
Alexis Howard
Joseph E. Duke-Cohan

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1712660

1,362 views

Review

Published on 03 Dec 2025

Advancing AAV vector manufacturing: challenges, innovations, and future directions for gene therapy

in Gene and Virotherapy

N. Charan S. S. Kowshik
Pushpendra Singh

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1709095

8,283 views
4 citations

Perspective

Published on 19 Nov 2025

MYC is in the CARDs: CBM complexes coordinate immune and MYC-dependent cellular function

in Molecular Pathology

Stanley B. DeVore
Gurjit K. Khurana Hershey

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1731823

1,300 views

Review

Published on 14 Oct 2025

Antibody-drug conjugates targeting the cadherin, claudin and nectin families of adhesion molecules

in Molecular Medicine and Cancer Treatment

Masuko Katoh
Yohann Loriot
Izuma Nakayama
Akinobu Hamada
Kohei Shitara
Masaru Katoh

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1661016

6,949 views
5 citations

Review

Published on 01 Oct 2025

AI-enabled resilience modeling for brain health

in Molecular Mechanisms of Neurodegeneration

Andrew Wister
Elizaveta Pinigina
Jie Liang
Igor Linkov

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1671337

2,734 views
1 citation

Review

Published on 29 Aug 2025

The role of aryl hydrocarbon receptor signalling in COVID-19 pathology and its therapeutic potential

in Molecular Pathology

Saidon Mbambara
Ndimo Modipane
Thato Serite
Mike Sathekge
Mankgopo Kgatle

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1599785

2,738 views
1 citation

Mini Review

Published on 26 Jun 2025

Potential role of N6-methyladenosine modification in circular RNA biogenesis and function in the inflammatory responses

in Molecular Microbes, Disease and Mechanisms of Immune Response

Heedoo Lee
Leo Chen
Yang Jin

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1607661

3,604 views
4 citations

Review

Published on 19 Jun 2025

Neural stem cells in adult neurogenesis and their therapeutic applications in neurodegenerative disorders: a concise review

in Molecular Mechanisms of Neurodegeneration

Teketay Bayleyegn Derso
Bemrew Admassu Mengistu
Yitayew Demessie
Melkie Dagnaw Fenta
Kalkidan Getnet

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1569717

11,159 views
8 citations

Editorial

Published on 02 Jun 2025

Editorial: Current trends in immunotherapy: from monoclonal antibodies to CAR-T cells

in Molecular Medicine and Cancer Treatment

Kishor Pant
Mark C. Glassy

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1633469

2,985 views

Editorial

Published on 16 May 2025

Editorial: Epigenetics and stem cell therapy in cancer and diseases

in Molecular Medicine and Cancer Treatment

Sonia Coni
Roberto Schirano
Camilla Manfredi
Paola Infante
Veronica Veschi

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1621093

2,448 views
1 citation

Review

Published on 20 Feb 2025

Cell surface vimentin: a natural human immune response target for immunotherapy

in Molecular Medicine and Cancer Treatment

Mark C. Glassy

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1552323

3,380 views
2 citations

Editorial

Published on 18 Feb 2025

Editorial: Tuberculosis: host immunity, diagnostics and therapeutics

in Molecular Microbes, Disease and Mechanisms of Immune Response

Anthony G. Tsolaki
Amy K. Barczak
Uday Kishore

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1568256

2,152 views

Review

Published on 13 Feb 2025

Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis

in Molecular Medicine and Cancer Treatment

D. Y. Mengistu
M. Terribili
C. Pellacani
L. Ciapponi
M. Marzullo

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1530719

6,578 views
4 citations

Editorial

Published on 11 Feb 2025

Editorial: Neuroinflammatory aspects in neurological disorders

in Molecular Mechanisms of Neurodegeneration

Pinto Alipio
Loidl C. Fabián
Goldstein Jorge

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1557546

2,222 views
1 citation

Editorial

Published on 09 Jan 2025

Editorial: Gene therapy and genome editing for metabolic liver disorders

in Gene and Virotherapy

Fanny Collaud
Giulia Bortolussi

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1543685

2,116 views
1 citation

Brief Research Report

Published on 08 Jan 2025

An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells

in Molecular Microbes, Disease and Mechanisms of Immune Response

Ashley King
Davis Noblitt
Olivia Sherron
Clara Kjerfve
Lydia Pless
Nicholas L. Truex

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1492370

4,800 views
1 citation

Original Research

Published on 06 Jan 2025

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model

in Molecular Medicine for Cardiology

Caroline Schoenherr
Stefan Pietzsch
Cristina Barca
Franziska E. Müller
Frauke S. Bahr
Martina Kasten
Andre Zeug
Sergej Erschow
Christine S. Falk
Evgeni Ponimaskin

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1487526

4,159 views
1 citation

94 articles

articles

Editorial: Targeted cancer therapy through metabolic pathways

Mapping the future of medicine through digital twins

Sirtuin 1 is a key molecular link between cellular senescence and heart failure

Molecular mechanisms underlying psoriasis and depression: an integrated analysis using mendelian randomization, transcriptomics, and single-cell sequencing

Blood biomarkers and atrial remodeling in patients at risk of atrial fibrillation

HIF1α reinforces PPARγ-dependent metabolic rechanneling to support lipid accumulation in adipocytes

CD19 exon 2 skipping is a potential prognostic correlate of anti-CD19 CAR-T therapy relapse

Association of specific HLA alleles in patients with interstitial cystitis suggesting autoimmunity

Advancing AAV vector manufacturing: challenges, innovations, and future directions for gene therapy

MYC is in the CARDs: CBM complexes coordinate immune and MYC-dependent cellular function

Antibody-drug conjugates targeting the cadherin, claudin and nectin families of adhesion molecules

AI-enabled resilience modeling for brain health

The role of aryl hydrocarbon receptor signalling in COVID-19 pathology and its therapeutic potential

Potential role of N6-methyladenosine modification in circular RNA biogenesis and function in the inflammatory responses

Neural stem cells in adult neurogenesis and their therapeutic applications in neurodegenerative disorders: a concise review

Editorial: Current trends in immunotherapy: from monoclonal antibodies to CAR-T cells

Editorial: Epigenetics and stem cell therapy in cancer and diseases

Cell surface vimentin: a natural human immune response target for immunotherapy

Editorial: Tuberculosis: host immunity, diagnostics and therapeutics

Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis

Editorial: Neuroinflammatory aspects in neurological disorders

Editorial: Gene therapy and genome editing for metabolic liver disorders

An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model