Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Editorial

Published on 17 Nov 2023

Editorial: The molecular mechanisms and potential drug targets for remyelination and neuroregeneration

in Brain Disease Mechanisms

Aleksandra Rutkowska
Maria Velasco-Estevez
Sinead A. O'Sullivan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1332594

2,390 views

Original Research

Published on 14 Nov 2023

Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

in Brain Disease Mechanisms

Nicole D. Schartz
Alisha Aroor
Yibo Li
Nicole Pinzón-Hoyos
Amy L. Brewster

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1265944

5,509 views
12 citations

Original Research

Published on 13 Nov 2023

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

in Brain Disease Mechanisms

Erika Kropf
Arman Shekari
Sama Jaberi
Anish Puri
Chengbiao Wu
Margaret Fahnestock

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1241420

3,963 views
4 citations

Original Research

Published on 09 Nov 2023

The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy

in Brain Disease Mechanisms

Nikhil S. Rao
Marson Putra
Christina Meyer
Aida Almanza
Thimmasettappa Thippeswamy

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1294514

4,461 views
10 citations

Original Research

Published on 09 Nov 2023

Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome

in Brain Disease Mechanisms

Magdalena Chojnacka
Anna Beroun
Marta Magnowska
Aleksandra Stawikowska
Dominik Cysewski
Jacek Milek
Magdalena Dziembowska
Bozena Kuzniewska

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1258615

3,608 views
10 citations

Original Research

Published on 06 Nov 2023

Prominent elevation of extracellular matrix molecules in intracerebral hemorrhage

in Brain Disease Mechanisms

Hongmin Li
Samira Ghorbani
Ruiyi Zhang
Vincent Ebacher
Erin L. Stephenson
Michael B. Keough
V. Wee Yong
Mengzhou Xue

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1251432

5,927 views
10 citations

Original Research

Published on 02 Nov 2023

Increased pituitary adenylate cyclase-activating peptide genes expression in the prefrontal cortex in schizophrenia in relation to suicide

in Brain Disease Mechanisms

Zala Slabe
Rawien A. Balesar
Ronald W. H. Verwer
Gorazd Drevenšek
Dick F. Swaab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1277958

4,031 views
5 citations

Original Research

Published on 30 Oct 2023

Identification ferroptosis-related hub genes and diagnostic model in Alzheimer’s disease

in Brain Disease Mechanisms

Huabin Zhao
Jiawei Wang
Zhongzheng Li
Shenghui Wang
Guoying Yu
Lan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1280639

7,241 views
16 citations

Original Research

Published on 30 Oct 2023

Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice

in Brain Disease Mechanisms

Xiaoxia Li
Yuan Gao
Baoying Li
Wenqian Zhao
Qian Cai
Wenbin Yin
Shudong Zeng
Xiaoli Li
Haiqing Gao
Mei Cheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1251513

4,805 views
1 citation

Original Research

Published on 27 Oct 2023

Plasma D-dimer levels are a biomarker for in-hospital complications and long-term mortality in patients with traumatic brain injury

in Brain Disease Mechanisms

Xinli Chen
Xiaohua Wang
Yingchao Liu
Xiumei Guo
Fan Wu
Yushen Yang
Weipeng Hu
Feng Zheng
Hefan He

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1276726

3,608 views
12 citations

Original Research

Published on 25 Oct 2023

ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes

in Brain Disease Mechanisms

Cali M. McEntee
Alyssa N. Cavalier
Thomas J. LaRocca

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1263369

5,334 views
10 citations

Original Research

Published on 25 Oct 2023

Whole exome sequencing of patients with varicella-zoster virus and herpes simplex virus induced acute retinal necrosis reveals rare disease-associated genetic variants

in Brain Disease Mechanisms

Johanna L. Heinz
Sigrid M. A. Swagemakers
Joanna von Hofsten
Marie Helleberg
Michelle M. Thomsen
Kerstin De Keukeleere
Joke H. de Boer
Tomas Ilginis
Georges M. G. M. Verjans
Peter M. van Hagen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1253040

5,461 views
7 citations

Original Research

Published on 24 Oct 2023

Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus

in Brain Disease Mechanisms

Fabio Cesar Tescarollo
Daniel Valdivia
Spencer Chen
Hai Sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1268311

5,141 views
4 citations

Mini Review

Published on 16 Oct 2023

Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

in Brain Disease Mechanisms

Gunnar Nordvall
Johan Lundkvist
Johan Sandin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1279740

13,703 views
28 citations

Original Research

Published on 16 Oct 2023

High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder

in Brain Disease Mechanisms

Areej Mesleh
Hanan Ehtewish
Katie Lennard
Houari B. Abdesselem
Fouad Al-Shaban
Julie Decock
Nehad M. Alajez
Abdelilah Arredouani
Mohamed M. Emara
Omar Albagha

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1222506

6,598 views
5 citations

Original Research

Published on 16 Oct 2023

The application of weighted gene co-expression network analysis and support vector machine learning in the screening of Parkinson’s disease biomarkers and construction of diagnostic models

in Brain Disease Mechanisms

Lijun Cai
Shuang Tang
Yin Liu
Yingwan Zhang
Qin Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1274268

5,325 views
6 citations

Original Research

Published on 13 Oct 2023

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75NTR signaling in the p75exonIII-KO mice

in Brain Disease Mechanisms

Raquel Comaposada-Baró
Andrea Benito-Martínez
Juan Julian Escribano-Saiz
María Luisa Franco
Lorenzo Ceccarelli
Isabel Calatayud-Baselga
Helena Mira
Marçal Vilar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1237458

5,774 views
8 citations

Original Research

Published on 12 Oct 2023

Deleterious and protective effects of epothilone-D alone and in the context of amyloid β- and tau-induced alterations

in Brain Disease Mechanisms

Ángel Abdiel Robles-Gómez
Benito Ordaz
Jonathan-Julio Lorea-Hernández
Fernando Peña-Ortega

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1198299

3,677 views
5 citations

Original Research

Published on 10 Oct 2023

Circulating microRNAs correlate with structural and functional MRI parameters in patients with multiple sclerosis

in Brain Disease Mechanisms

Lili Geiger
Gergely Orsi
Tamás Cseh
Katalin Gombos
Zsolt Illés
Boldizsár Czéh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1173212

4,221 views
10 citations

Original Research

Published on 28 Sep 2023

Unraveling the functional consequences of a novel germline missense mutation (R38C) in the yeast model of succinate dehydrogenase subunit B: insights into neurodegenerative disorders

in Brain Disease Mechanisms

Jiatong Zheng
Siru Liu
Dongdong Wang
Linlin Li
Surendra Sarsaiya
Hua Zhou
Heng Cai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1246842

4,180 views
3 citations

Original Research

Published on 28 Sep 2023

A quest for the stereo-electronic requirements for selective agonism for the neurotrophin receptors TrkA and TrkB in 17-spirocyclic-dehydroepiandrosterone derivatives

in Brain Disease Mechanisms

Daniele Narducci
Despoina Charou
Thanasis Rogdakis
Ioanna Zota
Vivi Bafiti
Maria Zervou
Theodora Katsila
Achille Gravanis
Kyriakos C. Prousis
Ioannis Charalampopoulos

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1244133

4,974 views
5 citations

Correction

Published on 27 Sep 2023

Corrigendum: Interferon-induced transmembrane protein 3 in the hippocampus: a potential novel target for the therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy

in Brain Disease Mechanisms

Nan Li
Rui-Hang Ma
Er-Fei Zhang
Feng Ge
De-Yu Fang
Jing Zhang
Yan-Ning Zhang
Yan Gao
Li-Chao Hou
Hong-Xu Jin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1294087

3,425 views

Original Research

Published on 22 Sep 2023

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy

in Brain Disease Mechanisms

Elizabeth Brindley
Mona Heiland
Catherine Mooney
Mairead Diviney
Omar Mamad
Thomas D. M. Hill
Yan Yan
Morten T. Venø
Cristina R. Reschke
Aasia Batool

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1230942

6,049 views
16 citations

Original Research

Published on 18 Sep 2023

The miRNA transcriptome of cerebrospinal fluid in preterm infants reveals the signaling pathways that promote reactive gliosis following cerebral hemorrhage

in Brain Disease Mechanisms

Andriana Gialeli
Robert Spaull
Torsten Plösch
James Uney
Oscar Cordero Llana
Axel Heep

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1211373

3,770 views
3 citations

1,115 articles

articles

Editorial: The molecular mechanisms and potential drug targets for remyelination and neuroregeneration

Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75NTR

The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy

Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome

Prominent elevation of extracellular matrix molecules in intracerebral hemorrhage

Increased pituitary adenylate cyclase-activating peptide genes expression in the prefrontal cortex in schizophrenia in relation to suicide

Identification ferroptosis-related hub genes and diagnostic model in Alzheimer’s disease

Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice

Plasma D-dimer levels are a biomarker for in-hospital complications and long-term mortality in patients with traumatic brain injury

ADAR1 suppression causes interferon signaling and transposable element transcript accumulation in human astrocytes

Whole exome sequencing of patients with varicella-zoster virus and herpes simplex virus induced acute retinal necrosis reveals rare disease-associated genetic variants

Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus

Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder

The application of weighted gene co-expression network analysis and support vector machine learning in the screening of Parkinson’s disease biomarkers and construction of diagnostic models

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75NTR signaling in the p75exonIII-KO mice

Deleterious and protective effects of epothilone-D alone and in the context of amyloid β- and tau-induced alterations

Circulating microRNAs correlate with structural and functional MRI parameters in patients with multiple sclerosis

Unraveling the functional consequences of a novel germline missense mutation (R38C) in the yeast model of succinate dehydrogenase subunit B: insights into neurodegenerative disorders

A quest for the stereo-electronic requirements for selective agonism for the neurotrophin receptors TrkA and TrkB in 17-spirocyclic-dehydroepiandrosterone derivatives

Corrigendum: Interferon-induced transmembrane protein 3 in the hippocampus: a potential novel target for the therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy

The miRNA transcriptome of cerebrospinal fluid in preterm infants reveals the signaling pathways that promote reactive gliosis following cerebral hemorrhage