Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 09 Aug 2021

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia

in Brain Disease Mechanisms

Steven W. Bothwell
Daniel Omileke
Rebecca J. Hood
Debbie-Gai Pepperall
Sara Azarpeykan
Adjanie Patabendige
Neil J. Spratt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.712779

7,460 views
13 citations

Brief Research Report

Published on 09 Aug 2021

Miro1 Impairment in a Parkinson’s At-Risk Cohort

in Brain Disease Mechanisms

David Nguyen
Vinita Bharat
Devon M. Conradson
Pawan Nandakishore
Xinnan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.734273

7,847 views
18 citations

Review

Published on 09 Aug 2021

Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS

in Brain Disease Mechanisms

Clara Tejido
Donya Pakravan
Ludo Van Den Bosch

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.686995

11,634 views
25 citations

Mini Review

Published on 04 Aug 2021

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

in Brain Disease Mechanisms

Meng Zhang
Ping He
Zhigang Bian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.685143

10,630 views
64 citations

Original Research

Published on 27 Jul 2021

The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

in Brain Disease Mechanisms

Björn Heinrichs
Baowen Liu
Jin Zhang
Jannis E. Meents
Kim Le
Andelain Erickson
Petra Hautvast
Xiwen Zhu
Ningbo Li
Yi Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.709228

8,579 views
2 citations

Original Research

Published on 26 Jul 2021

Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy

in Brain Disease Mechanisms

Lijun Dai
Jiannan Wang
Mingyang He
Min Xiong
Ye Tian
Chaoyang Liu
Zhentao Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.682320

7,234 views
12 citations

Review

Published on 23 Jul 2021

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities

in Brain Disease Mechanisms

Joke Terryn
Catherine M. Verfaillie
Philip Van Damme

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.713031

21,592 views
46 citations

Original Research

Published on 19 Jul 2021

Expression Analysis of Ermin and Listerin E3 Ubiquitin Protein Ligase 1 Genes in Autistic Patients

in Brain Disease Mechanisms

Shadi Shiva
Jalal Gharesouran
Hani Sabaie
Mohammad Reza Asadi
Shahram Arsang-Jang
Mohammad Taheri
Maryam Rezazadeh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.701977

4,979 views
8 citations

Mini Review

Published on 16 Jul 2021

Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

in Brain Disease Mechanisms

Melanie J. Grubisha
Robert A. Sweet
Matthew L. MacDonald

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.689495

7,838 views
6 citations

Original Research

Published on 09 Jul 2021

Age-Related Transcriptional Deregulation of Genes Coding Synaptic Proteins in Alzheimer's Disease Murine Model: Potential Neuroprotective Effect of Fingolimod

in Brain Disease Mechanisms

Henryk Jęśko
Iga Wieczorek
Przemysław Leonard Wencel
Magdalena Gąssowska-Dobrowolska
Walter J. Lukiw
Robert Piotr Strosznajder

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.660104

6,990 views
26 citations

Mini Review

Published on 08 Jul 2021

Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

in Brain Disease Mechanisms

Francesca Bufalieri
Irene Basili
Lucia Di Marcotullio
Paola Infante

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.710171

5,865 views
13 citations

Original Research

Published on 06 Jul 2021

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

in Brain Disease Mechanisms

Moataz Badawi
Takuma Mori
Taiga Kurihara
Takahiro Yoshizawa
Katsuhiro Nohara
Emi Kouyama-Suzuki
Toru Yanagawa
Yoshinori Shirai
Katsuhiko Tabuchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.706494

6,738 views
21 citations

Mini Review

Published on 05 Jul 2021

The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders

in Brain Disease Mechanisms

Janelle E. Stanton
Sigita Malijauskaite
Kieran McGourty
Andreas M. Grabrucker

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.695873

8,407 views
12 citations

Review

Published on 01 Jul 2021

The Molecular Basis of Depression: Implications of Sex-Related Differences in Epigenetic Regulation

in Brain Disease Mechanisms

Ayako Kawatake-Kuno
Toshiya Murai
Shusaku Uchida

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.708004

11,821 views
21 citations

Original Research

Published on 24 Jun 2021

Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

in Brain Disease Mechanisms

Agnes Molnar-Kasza
Barbara Hinteregger
Joerg Neddens
Roland Rabl
Stefanie Flunkert
Birgit Hutter-Paier

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.681868

9,807 views
7 citations

Perspective

Published on 17 Jun 2021

Synaptic Plasticity and Oscillations in Alzheimer’s Disease: A Complex Picture of a Multifaceted Disease

in Brain Disease Mechanisms

Yuniesky Andrade-Talavera
Antonio Rodríguez-Moreno

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.696476

8,846 views
34 citations

Perspective

Published on 15 Jun 2021

Conceptual and Methodological Pitfalls in Experimental Studies: An Overview, and the Case of Alzheimer’s Disease

in Brain Disease Mechanisms

Daniela Puzzo
Fiorenzo Conti

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.684977

4,227 views
5 citations

Review

Published on 14 Jun 2021

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

in Brain Disease Mechanisms

Seiichi Nagano
Toshiyuki Araki

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.697973

14,266 views
31 citations

Mini Review

Published on 28 May 2021

Astroglial Connexins in Neurodegenerative Diseases

in Brain Disease Mechanisms

Xiaomin Huang
Yixun Su
Nan Wang
Hui Li
Zhigang Li
Guowei Yin
Hui Chen
Jianqin Niu
Chenju Yi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.657514

10,293 views
47 citations

Original Research

Published on 21 May 2021

CircRNA-ceRNA Network Revealing the Potential Regulatory Roles of CircRNA in Alzheimer’s Disease Involved the cGMP-PKG Signal Pathway

in Brain Disease Mechanisms

Yuan Zhang
Lili Qian
Yingying Liu
Ying Liu
Wanpeng Yu
Yanfang Zhao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.665788

11,478 views
43 citations

Brief Research Report

Published on 13 May 2021

Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency

in Brain Disease Mechanisms

Katarzyna Gaweda-Walerych
Dawid Walerych
Mariusz Berdyński
Emanuele Buratti
Cezary Zekanowski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.676478

5,886 views
17 citations

Mini Review

Published on 11 May 2021

Microglial Exosomes in Neurodegenerative Disease

in Brain Disease Mechanisms

Min Guo
Yining Hao
Yiwei Feng
Haiqing Li
Yiting Mao
Qiang Dong
Mei Cui

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.630808

25,014 views
88 citations

Specialty Grand Challenge

Published on 10 May 2021

Specialty Grand Challenge for Brain Disease Mechanisms

in Brain Disease Mechanisms

Detlev Boison

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.689903

3,523 views
1 citation

Original Research

Published on 29 Apr 2021

Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population

in Brain Disease Mechanisms

Sunil Q. Mehta
Supriya Behl
Patrick L. Day
Adriana M. Delgado
Nicholas B. Larson
Lindsay R. Stromback
Andrea R. Huebner
Timothy R. DeGrado
Jessica M. Davis
Paul J. Jannetto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.665686

6,503 views
22 citations

1,115 articles

articles

Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia

Miro1 Impairment in a Parkinson’s At-Risk Cohort

Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

The Potential Effect of Nav1.8 in Autism Spectrum Disorder: Evidence From a Congenital Case With Compound Heterozygous SCN10A Mutations

Lovastatin Alleviates α-Synuclein Aggregation and Phosphorylation in Cellular Models of Synucleinopathy

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities

Expression Analysis of Ermin and Listerin E3 Ubiquitin Protein Ligase 1 Genes in Autistic Patients

Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

Age-Related Transcriptional Deregulation of Genes Coding Synaptic Proteins in Alzheimer's Disease Murine Model: Potential Neuroprotective Effect of Fingolimod

Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders

The Molecular Basis of Depression: Implications of Sex-Related Differences in Epigenetic Regulation

Evaluation of Neuropathological Features in the SOD1-G93A Low Copy Number Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Synaptic Plasticity and Oscillations in Alzheimer’s Disease: A Complex Picture of a Multifaceted Disease

Conceptual and Methodological Pitfalls in Experimental Studies: An Overview, and the Case of Alzheimer’s Disease

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

Astroglial Connexins in Neurodegenerative Diseases

CircRNA-ceRNA Network Revealing the Potential Regulatory Roles of CircRNA in Alzheimer’s Disease Involved the cGMP-PKG Signal Pathway

Parkin Levels Decrease in Fibroblasts With Progranulin (PGRN) Pathogenic Variants and in a Cellular Model of PGRN Deficiency

Microglial Exosomes in Neurodegenerative Disease

Specialty Grand Challenge for Brain Disease Mechanisms

Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population