Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 10 Apr 2024

PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling

in Brain Disease Mechanisms

Guillermo Moya-Alvarado
Xavier Valero-Peña
Alejandro Aguirre-Soto
Fernando J. Bustos
Oscar M. Lazo
Francisca C. Bronfman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1009404

4,965 views
10 citations

Original Research

Published on 05 Apr 2024

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone

in Brain Disease Mechanisms

Shreya H. Dhume
Kayode Balogun
Ambalika Sarkar
Sebastian Acosta
Howard T. J. Mount
Lindsay S. Cahill
John G. Sled
Lena Serghides

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1376681

3,671 views
2 citations

Review

Published on 04 Apr 2024

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

in Brain Disease Mechanisms

Minqi Cai
Qian Zheng
Yiqiang Chen
Siyuan Liu
Huimin Zhu
Bing Bai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379726

4,998 views
11 citations

Correction

Published on 04 Apr 2024

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

in Brain Disease Mechanisms

Basharat Hussain
Cheng Fang
Xiaowen Huang
Ziying Feng
Yuxuan Yao
Yu Wang
Junlei Chang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379436

1,304 views

Review

Published on 03 Apr 2024

Morphogenetic theory of mental and cognitive disorders: the role of neurotrophic and guidance molecules

in Brain Disease Mechanisms

Alexandra Primak
Kirill Bozov
Kseniya Rubina
Stalik Dzhauari
Elena Neyfeld
Maria Illarionova
Ekaterina Semina
Dmitriy Sheleg
Vsevolod Tkachuk
Maxim Karagyaur

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1361764

3,777 views
2 citations

Mini Review

Published on 28 Mar 2024

Cuproptosis in stroke: focusing on pathogenesis and treatment

in Brain Disease Mechanisms

Liwei Xing
Zhifeng Wang
Zhihui Hao
Pan Pan
Aiming Yang
Jian Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1349123

5,814 views
7 citations

Editorial

Published on 26 Mar 2024

Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia

in Brain Disease Mechanisms

Josué Orlando Ramírez-Jarquín
Angeles C. Tecalco-Cruz
Violeta Gisselle Lopez-Huerta
Uri Nimrod Ramírez-Jarquín

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398127

2,342 views

Review

Published on 22 Mar 2024

Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage

in Brain Disease Mechanisms

Marguerite Jamet
Luc Dupuis
Jose-Luis Gonzalez De Aguilar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1375330

7,308 views
6 citations

Original Research

Published on 21 Mar 2024

Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation

in Brain Disease Mechanisms

Miho Watanabe
Adya Saran Sinha
Yohei Shinmyo
Atsuo Fukuda

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1373337

4,589 views

Editorial

Published on 18 Mar 2024

Editorial: Proteostasis in central nervous system disorders

in Brain Disease Mechanisms

An Zhou
Fang Bian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1394171

2,737 views

Review

Published on 13 Mar 2024

Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?

in Brain Disease Mechanisms

Antonio d’Amati
Lavinia Bargiacchi
Sabrina Rossi
Andrea Carai
Luca Bertero
Valeria Barresi
Maria Elena Errico
Anna Maria Buccoliero
Sofia Asioli
Gianluca Marucci

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1268038

25,641 views
17 citations

Original Research

Published on 13 Mar 2024

The altered TBI fecal microbiome is stable and functionally distinct

in Brain Disease Mechanisms

Richard B. Pyles
Aaron L. Miller
Randall J. Urban
Melinda Sheffield-Moore
Traver J. Wright
Carrie A. Maxwell
Kathleen M. Randolph
Christopher P. Danesi
Kristen A. McGovern
Jayson Vargas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1341808

6,310 views
14 citations

Original Research

Published on 11 Mar 2024

Activation of nucleus accumbens projections to the ventral tegmental area alters molecular signaling and neurotransmission in the reward system

in Brain Disease Mechanisms

Alaa Khayat
Rami Yaka

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1271654

6,154 views
1 citation

Review

Published on 11 Mar 2024

A recognition of exosomes as regulators of epigenetic mechanisms in central nervous system diseases

in Brain Disease Mechanisms

Shunxin Hu
Lei Feng
Zhonghong Yang
Xuechen Fan
Haozheng Gao
Tiancai Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1370449

4,726 views
9 citations

Brief Research Report

Published on 07 Mar 2024

Correlation of telomere length in brain tissue with peripheral tissues in living human subjects

in Brain Disease Mechanisms

Annemarie J. Carver
Benjamin Hing
Benjamin A. Elser
Stephanie J. Lussier
Takehiko Yamanashi
Matthew A. Howard
Hiroto Kawasaki
Gen Shinozaki
Hanna E. Stevens

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1303974

3,742 views
3 citations

Review

Published on 04 Mar 2024

New implications for prion diseases therapy and prophylaxis

in Brain Disease Mechanisms

Fangzhou Liu
Wenqi Lü
Ling Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1324702

24,344 views
12 citations

Perspective

Published on 29 Feb 2024

Brain, behavior, and physiological changes associated with predator stress–An animal model for trauma exposure in adult and neonatal rats

in Brain Disease Mechanisms

Stacey L. Kigar
Amelia Cuarenta
Carla L. Zuniga
Liza Chang
Anthony P. Auger
Vaishali P. Bakshi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1322273

3,620 views
10 citations

Brief Research Report

Published on 27 Feb 2024

Non-severe thermal burn injuries induce long-lasting downregulation of gene expression in cortical excitatory neurons and microglia

in Brain Disease Mechanisms

Rebecca C. S. Ong
Jamie L. Beros
Kathy Fuller
Fiona M. Wood
Phillip E. Melton
Jennifer Rodger
Mark W. Fear
Lucy Barrett
Andrew W. Stevenson
Alexander D. Tang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1368905

3,363 views
3 citations

Original Research

Published on 26 Feb 2024

LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons

in Brain Disease Mechanisms

Dinesh Devadoss
Juliet Akkaoui
Madhavan Nair
Madepalli K. Lakshmana

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1365752

3,815 views
1 citation

Review

Published on 14 Feb 2024

Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives

in Brain Disease Mechanisms

Hao Dong
Xin Wen
Bai-Wen Zhang
Zhe Wu
Wei Zou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1327472

6,559 views
4 citations

Original Research

Published on 08 Feb 2024

Different reactive profiles of calmodulin in the CSF samples of Chinese patients of four types of genetic prion diseases

in Brain Disease Mechanisms

Xiao-Xi Jia
Chao Hu
Cao Chen
Li-Ping Gao
Dong-Lin Liang
Wei Zhou
Run-Dong Cao
Kang Xiao
Qi Shi
Xiao-Ping Dong

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1341886

4,576 views
1 citation

Original Research

Published on 07 Feb 2024

Identification of hub genes significantly linked to temporal lobe epilepsy and apoptosis via bioinformatics analysis

in Brain Disease Mechanisms

Weiliang Wang
Yinghao Ren
Fei Xu
Xiaobin Zhang
Fengpeng Wang
Tianyu Wang
Huijuan Zhong
Xin Wang
Yi Yao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1300348

5,659 views
2 citations

Original Research

Published on 07 Feb 2024

Restoring GABAB receptor expression in the ventral tegmental area of methamphetamine addicted mice inhibits locomotor sensitization and drug seeking behavior

in Brain Disease Mechanisms

Mohammad Hleihil
Dietmar Benke

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1347228

6,123 views
7 citations

Original Research

Published on 31 Jan 2024

The coherence between PSMC6 and α-ring in the 26S proteasome is associated with Alzheimer’s disease

in Brain Disease Mechanisms

Jing Xiong
Xinping Pang
Xianghu Song
Lin Yang
Chaoyang Pang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1330853

4,209 views
6 citations

1,099 articles

articles

PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

Morphogenetic theory of mental and cognitive disorders: the role of neurotrophic and guidance molecules

Cuproptosis in stroke: focusing on pathogenesis and treatment

Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia

Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage

Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation

Editorial: Proteostasis in central nervous system disorders

Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?

The altered TBI fecal microbiome is stable and functionally distinct

Activation of nucleus accumbens projections to the ventral tegmental area alters molecular signaling and neurotransmission in the reward system

A recognition of exosomes as regulators of epigenetic mechanisms in central nervous system diseases

Correlation of telomere length in brain tissue with peripheral tissues in living human subjects

New implications for prion diseases therapy and prophylaxis

Brain, behavior, and physiological changes associated with predator stress–An animal model for trauma exposure in adult and neonatal rats

Non-severe thermal burn injuries induce long-lasting downregulation of gene expression in cortical excitatory neurons and microglia

LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons

Astrocytes in intracerebral hemorrhage: impact and therapeutic objectives

Different reactive profiles of calmodulin in the CSF samples of Chinese patients of four types of genetic prion diseases

Identification of hub genes significantly linked to temporal lobe epilepsy and apoptosis via bioinformatics analysis

Restoring GABAB receptor expression in the ventral tegmental area of methamphetamine addicted mice inhibits locomotor sensitization and drug seeking behavior

The coherence between PSMC6 and α-ring in the 26S proteasome is associated with Alzheimer’s disease