Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 29 Jan 2024

Human iPSC-derived neurons reveal NMDAR-independent dysfunction following HIV-associated insults

in Brain Disease Mechanisms

Alexander Starr
Emily Nickoloff-Bybel
Razan Abedalthaqafi
Naela Albloushi
Kelly L. Jordan-Sciutto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1353562

3,696 views
1 citation

Mini Review

Published on 22 Jan 2024

Role of C9orf72 hexanucleotide repeat expansions in ALS/FTD pathogenesis

in Brain Disease Mechanisms

Yanyan Geng
Qixu Cai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1322720

8,791 views
15 citations

Original Research

Published on 17 Jan 2024

Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer’s disease by capillary western blotting

in Brain Disease Mechanisms

Luke T. Milham
Gary P. Morris
Lyndsey M. Konen
Peggy Rentsch
Nesli Avgan
Bryce Vissel

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1338065

5,821 views
3 citations

Original Research

Published on 16 Jan 2024

A novel hydro-pneumatic fluid percussion device for inducing traumatic brain injury: assessment of sensory, motor, cognitive, molecular, and morphological outcomes in rodents

in Brain Disease Mechanisms

Alberto Morales-Villagrán
Juan C. Salazar-Sánchez
Gustavo A. Chiprés-Tinajero
Laura Medina-Ceja
Jorge Ortega-Ibarra

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1208954

2,326 views
3 citations

Original Research

Published on 16 Jan 2024

Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3

in Brain Disease Mechanisms

Patrizia Ratano
Germana Cocozza
Cecilia Pinchera
Ludovica Maria Busdraghi
Iva Cantando
Katiuscia Martinello
Mariarosaria Scioli
Maria Rosito
Paola Bezzi
Sergio Fucile

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1333745

4,170 views
4 citations

Original Research

Published on 12 Jan 2024

ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration

in Brain Disease Mechanisms

Jerome Clasadonte
Tania Deprez
Gabriel S. Stephens
Georges Mairet-Coello
Pierre-Yves Cortin
Maxime Boutier
Aurore Frey
Jeannie Chin
Marek Rajman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1324922

5,124 views
4 citations

Review

Published on 08 Jan 2024

Molecular pathways underlying sympathetic autonomic overshooting leading to fear and traumatic memories: looking for alternative therapeutic options for post-traumatic stress disorder

in Brain Disease Mechanisms

Márcia Azevedo
Raquel Martinho
Ana Oliveira
Paulo Correia-de-Sá
Mónica Moreira-Rodrigues

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1332348

6,382 views
8 citations

Original Research

Published on 08 Jan 2024

Differential diagnosis of mild cognitive impairment of Alzheimer’s disease by Simoa p-tau181 measurements with matching plasma and CSF

in Brain Disease Mechanisms

Ling Wu
Stephanie Arvai
Shih-Hsiu J. Wang
Andy J. Liu
Bin Xu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1288930

5,687 views
2 citations

Original Research

Published on 08 Jan 2024

The role of the brainstem in sleep disturbances and chronic pain of Gulf War and Iraq/Afghanistan veterans

in Brain Disease Mechanisms

Yu Zhang
Matthew Moore
Jennifer S. Jennings
J. David Clark
Peter J. Bayley
J. Wesson Ashford
Ansgar J. Furst

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1266408

4,428 views
3 citations

Review

Published on 05 Jan 2024

The function of previously unappreciated exerkines secreted by muscle in regulation of neurodegenerative diseases

in Brain Disease Mechanisms

Xuepeng Bian
Qian Wang
Yibing Wang
Shujie Lou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1305208

6,458 views
15 citations

Original Research

Published on 05 Jan 2024

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

in Brain Disease Mechanisms

Sandra M. Díaz-Rodríguez
M. Javier Herrero-Turrión
Carlos García-Peral
Ricardo Gómez-Nieto

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1322750

4,295 views
5 citations

Original Research

Published on 05 Jan 2024

DLG3 variants caused X-linked epilepsy with/without neurodevelopmental disorders and the genotype-phenotype correlation

in Brain Disease Mechanisms

Yun-Yan He
Sheng Luo
Liang Jin
Peng-Yu Wang
Jie Xu
Hong-Liang Jiao
Hong-Jun Yan
Yao Wang
Qiong-Xiang Zhai
Jing-Jing Ji

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1290919

5,763 views
15 citations

Mini Review

Published on 05 Jan 2024

Emerging perspectives of synaptic biomarkers in ALS and FTD

in Brain Disease Mechanisms

Karrthik Krishnamurthy
Raj Kumar Pradhan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1279999

9,356 views
9 citations

Original Research

Published on 04 Jan 2024

Blocking of microglia-astrocyte proinflammatory signaling is beneficial following stroke

in Brain Disease Mechanisms

Kimberly Prescott
Alexandra E. Münch
Evan Brahms
Maya K. Weigel
Kenya Inoue
Marion S. Buckwalter
Shane A. Liddelow
Todd C. Peterson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1305949

6,950 views
11 citations

Review

Published on 21 Dec 2023

Emerging diagnostic markers and therapeutic targets in post-stroke hemorrhagic transformation and brain edema

in Brain Disease Mechanisms

Ying Yao
Fei Liu
Zhaowen Gu
Jingyu Wang
Lintao Xu
Yue Yu
Jing Cai
Reng Ren

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1286351

10,089 views
9 citations

Original Research

Published on 20 Dec 2023

The profiles and clinical significance of extraocular muscle-expressed lncRNAs and mRNAs in oculomotor nerve palsy

in Brain Disease Mechanisms

Lianqun Wu
Mingsu Shi
Yu Liang
Jiaqiu Huang
Weiyi Xia
Hewei Bian
Qiao Zhuo
Chen Zhao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1293344

5,366 views
1 citation

Original Research

Published on 18 Dec 2023

Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation

in Brain Disease Mechanisms

Ali Tawbeh
Quentin Raas
Mounia Tahri-Joutey
Céline Keime
Romain Kaiser
Doriane Trompier
Boubker Nasser
Emma Bellanger
Marie Dessard
Yannick Hamon

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1299314

11,318 views
11 citations

Brief Research Report

Published on 18 Dec 2023

Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo

in Brain Disease Mechanisms

Pranav Vemula
Kathleen M. Schoch
Timothy M. Miller

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1320182

6,245 views
1 citation

Original Research

Published on 13 Dec 2023

Biomarkers for predicting the severity of spinal cord injury by proteomic analysis

in Brain Disease Mechanisms

Liangfeng Wei
Yubei Huang
Yehuang Chen
Jianwu Wu
Kaiqin Chen
Zhaocong Zheng
Shousen Wang
Liang Xue

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1153230

4,000 views
7 citations

Editorial

Published on 12 Dec 2023

Editorial: Neuropsychiatric and neurodegenerative aspects of acute and long COVID

in Brain Disease Mechanisms

Abbas F. Almulla
Hussein K. Al-Hakeim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1343930

2,004 views
2 citations

Original Research

Published on 11 Dec 2023

Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures

in Brain Disease Mechanisms

Hubert Monnerie
Micah Romer
Lindsay M. Roth
Caela Long
John S. Millar
Kelly L. Jordan-Sciutto
Judith B. Grinspan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1323431

4,453 views
2 citations

Original Research

Published on 05 Dec 2023

Differential expression of PSMC4, SKP1, and HSPA8 in Parkinson’s disease: insights from a Mexican mestizo population

in Brain Disease Mechanisms

Alma C. Salas-Leal
Sergio M. Salas-Pacheco
Erik I. Hernández-Cosaín
Lilia M. Vélez-Vélez
Elizabeth I. Antuna-Salcido
Francisco X. Castellanos-Juárez
Edna M. Méndez-Hernández
Osmel La Llave-León
Gerardo Quiñones-Canales
Oscar Arias-Carrión

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1298560

3,086 views
8 citations

Editorial

Published on 05 Dec 2023

Editorial: RNA binding proteins in neuroscience

in Brain Disease Mechanisms

Anca F. Savulescu
Epaminondas Doxakis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1340721

2,370 views

Review

Published on 05 Dec 2023

It’s a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease

in Brain Disease Mechanisms

Jane Dudley-Fraser
Katrin Rittinger

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1287257

4,734 views
11 citations

1,099 articles

articles

Human iPSC-derived neurons reveal NMDAR-independent dysfunction following HIV-associated insults

Role of C9orf72 hexanucleotide repeat expansions in ALS/FTD pathogenesis

Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer’s disease by capillary western blotting

A novel hydro-pneumatic fluid percussion device for inducing traumatic brain injury: assessment of sensory, motor, cognitive, molecular, and morphological outcomes in rodents

Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3

ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration

Molecular pathways underlying sympathetic autonomic overshooting leading to fear and traumatic memories: looking for alternative therapeutic options for post-traumatic stress disorder

Differential diagnosis of mild cognitive impairment of Alzheimer’s disease by Simoa p-tau181 measurements with matching plasma and CSF

The role of the brainstem in sleep disturbances and chronic pain of Gulf War and Iraq/Afghanistan veterans

The function of previously unappreciated exerkines secreted by muscle in regulation of neurodegenerative diseases

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

DLG3 variants caused X-linked epilepsy with/without neurodevelopmental disorders and the genotype-phenotype correlation

Emerging perspectives of synaptic biomarkers in ALS and FTD

Blocking of microglia-astrocyte proinflammatory signaling is beneficial following stroke

Emerging diagnostic markers and therapeutic targets in post-stroke hemorrhagic transformation and brain edema

The profiles and clinical significance of extraocular muscle-expressed lncRNAs and mRNAs in oculomotor nerve palsy

Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation

Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo

Biomarkers for predicting the severity of spinal cord injury by proteomic analysis

Editorial: Neuropsychiatric and neurodegenerative aspects of acute and long COVID

Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures

Differential expression of PSMC4, SKP1, and HSPA8 in Parkinson’s disease: insights from a Mexican mestizo population

Editorial: RNA binding proteins in neuroscience

It’s a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease