Frontiers in Molecular Neuroscience | Pain Mechanisms and Modulators

Original Research

Published on 03 Sep 2024

Reward system neurodynamics during menstrual pain modulated by COMT Val158Met polymorphisms

in Pain Mechanisms and Modulators

Pei-Shan Hsu
Ching-Hsiung Liu
Ching-Ju Yang
Lin-Chien Lee
Wei-Chi Li
Hsiang-Tai Chao
Ming-Wei Lin
Li-Fen Chen
Jen-Chuen Hsieh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1457602

2,116 views

Original Research

Published on 30 Aug 2024

Dock4 contributes to neuropathic pain by regulating spinal synaptic plasticity in mice

in Pain Mechanisms and Modulators

Qiaochu Fu
Hongyi Li
Zhuanxu Zhu
Wencui Li
Zhihua Ruan
Ruijie Chang
Huixia Wei
Xueqin Xu
Xunliang Xu
Yanqiong Wu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1417567

1,911 views

Original Research

Published on 06 Aug 2024

Coordination between midcingulate cortex and retrosplenial cortex in pain regulation

in Pain Mechanisms and Modulators

Yunya Qiu
Yan-Na Lian
Cheng Wu
Li Liu
Chen Zhang
Xiang-Yao Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1405532

1,596 views
2 citations

Original Research

Published on 17 Jul 2024

Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels

in Pain Mechanisms and Modulators

Gerald Z. Zhuang
William F. Goins
Munal B. Kandel
Marco Marzulli
Mingdi Zhang
Joseph C. Glorioso
Yuan Kang
Alexandra E. Levitt
Konstantinos D. Sarantopoulos
Roy C. Levitt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1416148

2,642 views
2 citations

Mini Review

Published on 26 Jun 2024

Treadmill running on neuropathic pain: via modulation of neuroinflammation

in Pain Mechanisms and Modulators

Wei-Chun He
Shuang-Long Hou
Kai-Bin Wang
Ning Xu
Ke Li
Ting Xiong
Jing Luo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1345864

2,716 views
1 citation

Original Research

Published on 24 Jun 2024

Methods for negating the impact of zinc contamination to allow characterization of positive allosteric modulators of glycine receptors

in Pain Mechanisms and Modulators

Casey I. Gallagher
David P. Bishop
Thomas E. Lockwood
Tristan Rawling
Robert J. Vandenberg

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1392715

1,238 views
1 citation

Original Research

Published on 22 May 2024

SIRT1-regulated ROS generation activates NMDAR2B phosphorylation to promote central sensitization and allodynia in a male chronic migraine rat model

in Pain Mechanisms and Modulators

Xiaoyan Zhang
Wei Zhang
Yanyun Wang
Yun Zhang
Dunke Zhang
Guangcheng Qin
Jiying Zhou
Lixue Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1387481

2,281 views
3 citations

Original Research

Published on 09 May 2024

rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels

in Pain Mechanisms and Modulators

Munal B. Kandel
Gerald Z. Zhuang
William F. Goins
Marco Marzulli
Mingdi Zhang
Joseph C. Glorioso
Yuan Kang
Alexandra E. Levitt
Wai-Meng Kwok
Roy C. Levitt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398839

2,928 views
5 citations

Original Research

Published on 09 May 2024

GnRH peripherally modulates nociceptor functions, exacerbating mechanical pain

in Pain Mechanisms and Modulators

Haiyan Zheng
Minseok Kim
Chaeun Kim
Yerin Kim
Pyung Sun Cho
Ji Yeon Lim
Hojin Lee
Hye-In Yun
Jungmin Choi
Sun Wook Hwang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1160435

1,983 views

Original Research

Published on 01 May 2024

Behavioral and pharmacological characterization of planarian nociception

in Pain Mechanisms and Modulators

Guillaume Reho
Yannick Menger
Yannick Goumon
Vincent Lelièvre
Hervé Cadiou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1368009

3,514 views
3 citations

Review

Published on 26 Mar 2024

Acupuncture for radicular pain: a review of analgesic mechanism

in Pain Mechanisms and Modulators

Hong-Lin Li
Yi Zhang
Jian-Wei Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1332876

7,895 views
6 citations

Review

Published on 28 Feb 2024

Advances in understanding migraine pathophysiology: a bench to bedside review of research insights and therapeutics

in Pain Mechanisms and Modulators

Kofi Frimpong-Manson
Yuma T. Ortiz
Lance R. McMahon
Jenny L. Wilkerson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1355281

16,639 views
10 citations

Original Research

Published on 21 Feb 2024

Machine learning-based evaluation of spontaneous pain and analgesics from cellular calcium signals in the mouse primary somatosensory cortex using explainable features

in Pain Mechanisms and Modulators

Myeong Seong Bak
Haney Park
Heera Yoon
Geehoon Chung
Hyunjin Shin
Soonho Shin
Tai Wan Kim
Kyungjoon Lee
U. Valentin Nägerl
Sang Jeong Kim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1356453

4,081 views

Original Research

Published on 14 Feb 2024

Tetrandrine alleviates oxaliplatin-induced mechanical allodynia via modulation of inflammation-related genes

in Pain Mechanisms and Modulators

Zhi-Ling Zhang
Zi-Yang Wu
Feng-Yu Liu
Hang-YuChen
Suo-Di Zhai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1333842

5,198 views
3 citations

Original Research

Published on 06 Feb 2024

Exploring gene signatures and regulatory networks in a rat model of sciatica: implications and validation in neuropathic pain

in Pain Mechanisms and Modulators

Mu Xu
Zhijian Wang
Gang Xu
Mengye Zhu
Daying Zhang
Yi Yan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1261217

2,047 views

Mini Review

Published on 30 Jan 2024

Mechanisms of transcranial direct current stimulation (tDCS) for pain in patients with fibromyalgia syndrome

in Pain Mechanisms and Modulators

Shan Wang
Shu-Hao Du
Xue-Qiang Wang
Jun-Yan Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1269636

6,211 views
2 citations