Frontiers in Molecular Neuroscience

Original Research

Published on 13 Feb 2025

Deciphering motor dysfunction and microglial activation in mThy1-α-synuclein mice: a comprehensive study of behavioral, gene expression, and methylation changes

Brett A. McGregor
Md. Obayed Raihan
Afrina Brishti
Junguk Hur
James E. Porter

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1544971

113 views

Review

Published on 13 Feb 2025

Extrinsic and intrinsic control of striatal cholinergic interneuron activity

Desh Deepak Ratna
Tanner Chase Francis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1528419

142 views

Review

Published on 11 Feb 2025

The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders

Sean D. Fraser
Robert J. Harvey

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1550863

196 views

Editorial

Published on 07 Feb 2025

Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics

Tomohisa Hosokawa
Yoshiyuki Kubota
Tetsuya Takano

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564028

141 views

Original Research

Accepted on 06 Feb 2025

Impaired Cerebrospinal Fluid Circulation and Cerebral Lymphatic Drainage in a Rat Model of Chronic Hydrocephalus

Dong Bin Back
Bo-Ryoung Choi
Kyoung Ja Kwon
Dong-Hee Choi
Chan Young Shin
Jongmin Lee
Hahn Young Kim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1516265

Editorial

Published on 06 Feb 2025

Editorial: Latest advances in neuroscience at the 9th Croatian Neuroscience Congress

Kristina Mlinac-Jerkovic
Marija Heffer
Svjetlana Kalanj-Bognar
Senka Blažetić

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563899

238 views

Original Research

Accepted on 05 Feb 2025

Hippocampal RNA-Seq in a F2 Cross of bHR/bLR rats 1 Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in an Animal Model of Temperament

Elaine K Hebda-Bauer
Megan Hastings Hagenauer
Daniel Munro
Peter Blandino
Fan Meng
Keiko Arakawa
Apurva S Chitre
Ayse Bilge Ozel
Pejman Mohammadi
Stanley J Watson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1469467

Mini Review

Published on 05 Feb 2025

GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism

Tian Qiu
Ou Fu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1536577

335 views

Original Research

Published on 05 Feb 2025

The effect of AKT inhibition in α-synuclein-dependent neurodegeneration

Bedri Ranxhi
Zoya R. Bangash
Zachary M. Chbihi
Sokol V. Todi
Peter A. LeWitt
Wei-Ling Tsou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1524044

290 views

Original Research

Published on 05 Feb 2025

Ectopic expression of the cation-chloride cotransporter KCC2 in blood exosomes as a biomarker for functional rehabilitation

L. Caccialupi Da Prato
A. Rezzag Lebza
A. Consumi
M. Tessier
A. Srinivasan
C. Rivera
J. Laurin
C. Pellegrino

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1522571

218 views

Editorial

Published on 04 Feb 2025

Editorial: Nervous regeneration and functional recovery in the central and peripheral nervous systems: diagnostic methods, gene/cell therapies, and interventions

Dipa Natarajan
Ryo Hotta
Naho Fujiwara
Silvia Perin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1555390

178 views

Original Research

Published on 03 Feb 2025

Clinicopathological and molecular characterization of astrocytoma

Xiaoyan Wu
Wenfeng Peng
Xu Zhang
Tao Tang
Ling Deng
Yuxia Xu
Xiaoyun Liu
Fang Wang
Wujian Peng
Jianrong Huang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1483833

144 views

Original Research

Accepted on 30 Jan 2025

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

Melissa Alldred
Kyrillos W. Ibrahim
Harshitha Pidikiti
Sanghan Lee
Adriana Heguy
Gabriela Chiosis
Elliott Jay Mufson
Beth Stutzmann
Stephen D Ginsberg

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1546375

Original Research

Published on 30 Jan 2025

Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes

Ali Tawbeh
Catherine Gondcaille
Fatima-Ezzahra Saih
Quentin Raas
Damien Loichot
Yannick Hamon
Céline Keime
Alexandre Benani
Francesca Di Cara
Mustapha Cherkaoui-Malki

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1542938

536 views

Editorial

Accepted on 29 Jan 2025

Editorial: Neuroplasticity and Development

Giovanni Cirillo
Michele Papa

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1558715

135 views

Original Research

Accepted on 29 Jan 2025

Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegeneration in spastic ataxia type 5

Menekse Öztürk
Diran Herebian
Kale Dipali
Andreas Hentschel
Nina Rademacher
Florian Kraft
Rita Horvath
Felix Distelmaier
Sven Guenther Meuth
Tobias Ruck

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1548255

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Volumes

Volume 18 - 2025

Deciphering motor dysfunction and microglial activation in mThy1-α-synuclein mice: a comprehensive study of behavioral, gene expression, and methylation changes

Extrinsic and intrinsic control of striatal cholinergic interneuron activity

The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders

Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics

Impaired Cerebrospinal Fluid Circulation and Cerebral Lymphatic Drainage in a Rat Model of Chronic Hydrocephalus

Editorial: Latest advances in neuroscience at the 9th Croatian Neuroscience Congress

Hippocampal RNA-Seq in a F2 Cross of bHR/bLR rats 1 Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in an Animal Model of Temperament

GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism

The effect of AKT inhibition in α-synuclein-dependent neurodegeneration

Ectopic expression of the cation-chloride cotransporter KCC2 in blood exosomes as a biomarker for functional rehabilitation

Editorial: Nervous regeneration and functional recovery in the central and peripheral nervous systems: diagnostic methods, gene/cell therapies, and interventions

Clinicopathological and molecular characterization of astrocytoma

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes

Editorial: Neuroplasticity and Development

Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegeneration in spastic ataxia type 5